Combinative effect of sardine peptides and quercetin alleviates hypertension through inhibition of angiotensin I converting enzyme activity and inflammation

Food Research International

Volumn 100, Issue , 2017, Pages 579-585

  Luo, Jianming ^a,b   Zhang, Cheng ^b   Liu, Qianyue ^b   Ou, Shiyi ^b   Zhang, Lili ^b   Peng, Xichun ^b  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b JINAN UNIVERSITY   (China)

Author keywords

Angiotensin I converting enzyme; Anti hypertension; Inflammation; Quercetin; Sardine peptides

Indexed keywords

BLOOD PRESSURE; ENZYME ACTIVITY; ENZYMES; FLAVONOIDS; MIXTURES; PATHOLOGY; PEPTIDES; PHENOLS; PROTEINS;

ACE-INHIBITORY ACTIVITY; ANGIOTENSIN I-CONVERTING ENZYME; ANTI-HYPERTENSION; ANTIHYPERTENSIVE EFFECT; INFLAMMATION; QUERCETIN; SYSTOLIC BLOOD PRESSURE; TUMOR NECROSIS FACTOR ALPHA;

ENZYME INHIBITION;

ANTIHYPERTENSIVE AGENT; CYTOKINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FISH PROTEIN; PEPTIDE; QUERCETIN;

ANIMAL; BODY WEIGHT; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; INFLAMMATION; MALE; METABOLISM; MOUSE; RAT; RAW 264.7 CELL LINE; SPONTANEOUSLY HYPERTENSIVE RAT; WISTAR KYOTO RAT;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BODY WEIGHT; CELL SURVIVAL; CYTOKINES; FISH PROTEINS; INFLAMMATION; MALE; MICE; PEPTIDES; QUERCETIN; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RAW 264.7 CELLS;

EID: 85026449429     PISSN: 09639969     EISSN: 18737145     Source Type: Journal    
DOI: 10.1016/j.foodres.2017.07.019     Document Type: Article

References (45)

1. Actis-Goretta, L., Ottaviani, J.I., Fraga, C.G., Inhibition of angiotensin converting enzyme activity by flavanol-rich foods. Journal of Agricultural and Food Chemistry 54:1 (2006), 229–234.
2. Ademiluyi, A.O., Oboh, G., Phenolic-rich extracts from selected tropical underutilized legumes inhibit α-amylase, α-glucosidase, and angiotensin I converting enzyme in vitro. Journal of Basic and Clinical Physiology and Pharmacology 23:1 (2012), 17–25.
3. Akinyemi, A.J., Ademiluyi, A.O., Oboh, G., Aqueous extracts of two varieties of ginger (Zingiber officinale) inhibit angiotensin I-converting enzyme, iron (II), and sodium nitroprusside-induced lipid peroxidation in the rat heart in vitro. Journal of Medicinal Food 16:7 (2013), 641–646.
4. Al Shukor, N., Van Camp, J., Gonzales, G.B., Staljanssens, D., Struijs, K., Zotti, M.J., Smagghe, G., Angiotensin-converting enzyme inhibitory effects by plant phenolic compounds: A study of structure activity relationships. Journal of Agricultural and Food Chemistry 61:48 (2013), 11832–11839.
5. Baszczuk, A., Kopczyński, Z., Deręgowska, P., Pupek-Musialik, D., Cymerys, M., Kopczyński, J., Assessment of laboratory markers of inflammation in patients with primary hypertension. Nadcisnienie Tetnicze 15:4 (2011), 251–256.
6. Bautista, L.E., Vera, L.M., Arenas, I.A., Gamarra, G., Independent association between inflammatory markers (C-reactive protein, interleukin-6, and TNF-alpha) and essential hypertension. Journal of Human Hypertension 19:9 (2005), 149–154.
7. Bhagat, K., Vallance, P., Inflammatory cytokines impair endothelium-dependent dilatation in human veins in vivo. Circulation 96:9 (1997), 3042–3047.
8. Blake, G.J., Rifai, N., Buring, J.E., Ridker, P.M., Blood pressure, C-reactive protein, and risk of future cardiovascular events. Circulation 108:24 (2003), 2993–2999.
9. Boschin, G., Scigliuolo, G.M., Resta, D., Arnoldi, A., ACE-inhibitory activity of enzymatic protein hydrolysates from lupin and other legumes. Food Chemistry 145:7 (2014), 34–40.
10. Daskaya-Dikmen, C., Yucetepe, A., Karbancioglu-Guler, F., Daskaya, H., Ozcelik, B., Angiotensin-I-converting enzyme (ACE)-inhibitory peptides from plants. Nutrients, 9(4), 2017, E316.
11. de Oliveira-Sales, E.B., Nishi, E.E., Boim, M.A., Dolnikoff, M.S., Bergamaschi, C.T., Campos, R.R., Upregulation of AT1R and iNOS in the rostral ventrolateral medulla (RVLM) is essential for the sympathetic hyperactivity and hypertension in the 2K-1C Wistar rat model. American Journal of Hypertension 23:7 (2010), 708–715.
12. Dong, J., Xu, X., Liang, Y., Head, R., Bennett, L., Inhibition of angiotensin converting enzyme (ACE) activity by polyphenols from tea (Camellia sinensis) and links to processing method. Food & Function 2:6 (2011), 310–319.
13. Duarte, J., Pérez-Palencia, R., Vargas, F., Ocete, M.A., Pérez-Vizcaino, F., Zarzuelo, A., Tamargo, J., Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive rats. British Journal of Pharmacology 133:1 (2001), 117–124.
14. Guzik, T.J., Hoch, N.E., Brown, K.A., McCann, L.A., Rahman, A., Dikalov, S., Harrison, D.G., Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction. Journal of Experimental Medicine 204:10 (2007), 2449–2460.
15. Hampl, V., Bíbová, J., Banasová, A., Uhlik, J., Miková, D., Hnilicková, O., Herget, J., Pulmonary vascular iNOS induction participates in the onset of chronic hypoxic pulmonary hypertension. American Journal of Physiology - Lung Cellular and Molecular Physiology 290:1 (2006), L11–L20.
16. Hingorani, A.D., Cross, J., Kharbanda, R.K., Mullen, M.J., Bhagat, K., Taylor, M., Vallance, P., Acute systemic inflammation impairs endothelium-dependent dilatation in humans. Circulation 102:9 (2000), 994–999.
17. Huang, J., Liu, Q., Xue, B., Chen, L., Wang, Y., Ou, S., Peng, X., Angiotensin-I-converting enzyme inhibitory activities and in vivo antihypertensive effects of sardine protein hydrolysate. Journal of Food Science 81:11 (2016), H2831–H2840.
18. Huang, W.Y., Fu, L., Li, C.Y., Xu, L.P., Zhang, L.X., Zhang, W.M., Quercetin, hyperin, and chlorogenic acid improve endothelial function by antioxidant, antiinflammatory, and ACE inhibitory effects. Journal of Food Science 82:5 (2017), 1239–1246.
19. Ibrahim, H.R., Ahmed, A.S., Miyata, T., Novel angiotensin-converting enzyme inhibitory peptides from caseins and whey proteins of goat milk. Journal of Advanced Research 8:1 (2017), 63–71.
20. Irondi, E.A., Agboola, S.O., Oboh, G., Boligon, A.A., Inhibitory effect of leaves extracts of Ocimum basilicum and Ocimum gratissimum on two key enzymes involved in obesity and hypertension in vitro. Journal of Intercultural Ethnopharmacology 5:4 (2016), 396–402.
21. Irondi, E.A., Agboola, S.O., Oboh, G., Boligon, A.A., Athayde, M.L., Shode, F.O., Guava leaves polyphenolics-rich extract inhibits vital enzymes implicated in gout and hypertension in vitro. Journal of Intercultural Ethnopharmacology 5:2 (2016), 122–130.
22. Ito, H., Ohshima, A., Tsuzuki, M., Ohto, N., Takao, K., Hijii, C., Nishioka, K., Association of serum tumour necrosis factor-alpha with serum low-density lipoprotein-cholesterol and blood pressure in apparently healthy Japanese women. Clinical and Experimental Pharmacology and Physiology 28:3 (2011), 188–192.
23. Jimsheena, V.K., Gowda, L.R., Arachin derived peptides as selective angiotensin I-converting enzyme (ACE) inhibitors: Structure-activity relationship. Peptides 31:6 (2010), 1165–1176.
24. Lee, D.H., Kim, J.H., Park, J.S., Choi, Y.J., Lee, J.S., Isolation and characterization of a novel angiotensin I-converting enzyme inhibitory peptide derived from the edible mushroom Tricholoma giganteum. Peptides 25:4 (2004), 621–627.
25. Lee, D.L., Sturgis, L.C., Labazi, H., Osborne, J.B. Jr., Fleming, C., Pollock, J.S., Brands, M.W., Angiotensin II hypertension is attenuated in interleukin-6 knockout mice. American Journal of Physiology - Heart and Circulatory Physiology 290:3 (2006), H935–H940.
26. Lee, J.K., Hong, S., Jeon, J.K., Kim, S.K., Byun, H.G., Purification and characterization of angiotensin I converting enzyme inhibitory peptides from the rotifer, Brachionus rotundiformis. Bioresource Technology 100:21 (2009), 5255–5259.
27. Lee, S.B., Lee, W.S., Shin, J.S., Jang, D.S., Lee, K.T., Xanthotoxin suppresses LPS-induced expression of iNOS, COX-2, TNF-α, and IL-6 via AP-1, NF-κB, and JAK-STAT inactivation in RAW 264.7 macrophages. International Immunopharmacology 49 (2017), 21–29.
28. Li, Y., Wang, Y., Ding, X., Duan, B., Li, L., Wang, X., Serum levels of TNF-α and IL-6 are associated with pregnancy-induced hypertension. Reproductive Sciences 23:10 (2016), 1402–1408.
29. Lin, L., Lv, S., Li, B., Angiotensin-I-converting enzyme (ACE)-inhibitory and antihypertensive properties of squid skin gelatin hydrolysates. Food Chemistry 131:1 (2012), 225–230.
30. MacMicking, J., Xie, Q.W., Nathan, C., Nitric oxide and macrophage function. Annual Review of Immunology 15 (1997), 323–350.
31. Miguel, M., Aleixandre, A., Antihypertensive peptides derived from egg proteins. Journal of Nutrition 136:6 (2006), 1457–1460.
32. Muguruma, M., Ahhmed, A.M., Katayama, K., Kawahara, S., Maruyama, M., Nakamura, T., Identification of pro-drug type ACE inhibitory peptide sourced from porcine myosin B: Evaluation of its antihypertensive effects in vivo. Food Chemistry 114:2 (2009), 516–522.
33. Nam, J.S., Sharma, A.R., Nguyen, L.T., Chakraborty, C., Sharma, G., Lee, S.S., Application of bioactive quercetin in oncotherapy: From nutrition to nanomedicine. Molecules, 21(1), 2016, E108.
34. Okamoto, I., Abe, M., Shibata, K., Shimuzu, N., Sakata, N., Katsuragi, T., Tanaka, K., Evaluating the role of inducible nitric oxide synthase using a novel and selective inducible nitric oxide synthase inhibitor in septic lung injury produced by cecal ligation and puncture. American Journal of Respiratory and Critical Care Medicine 162:2 Pt 1 (2000), 716–722.
35. Persson, I.A., Persson, K., Andersson, R.G., Effect of Vaccinium myrtillus and its polyphenols on angiotensin-converting enzyme activity in human endothelial cells. Journal of Agricultural and Food Chemistry 57:11 (2009), 4626–4629.
36. Persson, I.A., Persson, K., Hägg, S., Andersson, R.G., Effects of cocoa extract and dark chocolate on angiotensin-converting enzyme and nitric oxide in human endothelial cells and healthy volunteers—a nutrigenomics perspective. Journal of Cardiovascular Pharmacology 57:1 (2011), 44–50.
37. Pruijm, M., Vollenweider, P., Mooser, V., Paccaud, F., Preisig, M., Waeber, G., Bochud, M., Inflammatory markers and blood pressure: Sex differences and the effect of fat mass in the CoLaus Study. Journal of Human Hypertension 27:3 (2013), 169–175.
38. Reinboth, M., Wolffram, S., Abraham, G., Ungemach, F.R., Cermak, R., Oral bioavailability of quercetin from different quercetin glycosides in dogs. British Journal of Nutrition 104:2 (2010), 198–203.
39. Robinson, L.J., Busconi, L., Michel, T., Agonist-modulated palmitoylation of endothelial nitric oxide synthase. Journal of Biological Chemistry 270:3 (1995), 995–998.
40. Song, H.Z., Lin, B., Lv, S., Lu, J., Ye, Y., Jiang, S., Lin, L., Antihypertensive effects of angiotensin-converting enzyme (ACE) inhibitory peptides from channel catfish skin gelatin. Modern Food Science and Technology 30:2 (2014), 78–83.
41. Sriramula, S., Cardinale, J.P., Francis, J., Inhibition of TNF in the brain reverses alterations in RAS components and attenuates angiotensin II-induced hypertension. PLoS One, 8(5), 2013, e63847.
42. Wang, W., Chen, W., Yang, Y., Liu, T., Yang, H., Xin, Z., New phenolic compounds from Coreopsis tinctoria Nutt. and their antioxidant and angiotensin i-converting enzyme inhibitory activities. Journal of Agricultural and Food Chemistry 63:1 (2015), 200–207.
43. Wang, X.X., Wei, Y.L., Liang, M.Q., Fish protein hydrolysates: Properties and applications (in Chinese). Acta Zoonutrimenta Sinica 24:9 (2012), 1636–1642.
44. Yang, H.Y., Erdos, E.G., Levin, Y., A dipeptidyl carboxypeptidase that converts angiotensin I and inactivates bradykinin. Biochimica et Biophysica Acta 214:2 (1970), 374–376.
45. Yang, H.Y., Erdos, E.G., Levin, Y., Characterization of a dipeptide hydrolase (kininase II: Angiotensin I converting enzyme). Journal of Pharmacology and Experimental Therapeutics 177:1 (1971), 291–300.