메뉴 건너뛰기




Volumn 5, Issue 12, 2009, Pages

Is new always better than old? The development of human vaccines for anthrax

Author keywords

Anthrax; Bacillus anthracis; Immunity; Pathogenicity; Vaccine

Indexed keywords

AMOXICILLIN; ANTHRAX VACCINE; ANTITOXIN; CHLORAMPHENICOL; CIPROFLOXACIN; DNA VACCINE; DOXYCYCLINE; ERYTHROMYCIN; GENTAMICIN; MYELOID DIFFERENTIATION FACTOR 88; PENICILLIN G; RECOMBINANT F1 V; RECOMBINANT PROTECTIVE ANTIGEN; RECOMBINANT PROTECTIVE ANTIGEN 102; SPARVAX; STERNE VACCINE; TC83; TETRACYCLINE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG; ANTHRAX TOXIN; BACTERIAL ANTIGEN; BACTERIAL TOXIN; IMMUNOLOGICAL ADJUVANT; RECOMBINANT PROTEIN;

EID: 85046915570     PISSN: 15548600     EISSN: 15548619     Source Type: Journal    
DOI: 10.4161/hv.9777     Document Type: Review
Times cited : (37)

References (137)
  • 1
    • 0025868227 scopus 로고
    • Anthrax vaccines: Past, present and future
    • Turnbull PC. Anthrax vaccines: past, present and future. Vaccine 1991; 9:533-9.
    • (1991) Vaccine , vol.9 , pp. 533-539
    • Turnbull, P.C.1
  • 2
    • 75449112787 scopus 로고    scopus 로고
    • th edn ed.,), Edward Amold Ltd., London 1975; 1672-94.
    • th edn ed.,), Edward Amold Ltd., London 1975; 1672-94.
  • 3
    • 75449091987 scopus 로고    scopus 로고
    • Koch R. Beitr z Biol d. Pflanzen 1876; 2:277-310.
    • Koch R. Beitr z Biol d. Pflanzen 1876; 2:277-310.
  • 4
    • 75449116893 scopus 로고    scopus 로고
    • Pasteur L. De I'attenuation des virus el de leur retour & la virulence. CR Acad Sci Agric Bulg 1881; 92:429-35.
    • Pasteur L. De I'attenuation des virus el de leur retour & la virulence. CR Acad Sci Agric Bulg 1881; 92:429-35.
  • 5
    • 0019250483 scopus 로고    scopus 로고
    • Tigertt WD. Anthrax. William Smith Greenfield MD, F.R.C.P., Professor Superintendent, the Brown Animal Sanatory Institution (1878-81). Concerning the priority due to him for the production of the first vaccine against anthrax. J Hyg (Lond) 1980; 85:415-20.
    • Tigertt WD. Anthrax. William Smith Greenfield MD, F.R.C.P., Professor Superintendent, the Brown Animal Sanatory Institution (1878-81). Concerning the priority due to him for the production of the first vaccine against anthrax. J Hyg (Lond) 1980; 85:415-20.
  • 7
    • 0030853307 scopus 로고    scopus 로고
    • Iraq's Biological Weapons, The past as future?
    • Zilinskas RA. Iraq's Biological Weapons, The past as future? JAMA 1997; 278:418-24.
    • (1997) JAMA , vol.278 , pp. 418-424
    • Zilinskas, R.A.1
  • 9
    • 0036053928 scopus 로고    scopus 로고
    • Bioterriorism: From threat to reality
    • Atlas RM. Bioterriorism: from threat to reality. Annu Rev Microbiol 2002; 56:167-85.
    • (2002) Annu Rev Microbiol , vol.56 , pp. 167-185
    • Atlas, R.M.1
  • 11
    • 0038752613 scopus 로고    scopus 로고
    • The Genome Sequence of Bacillus anthracis Ames and Comparison to Closely Related Bacteria
    • Read TD, Peterson SN, Tourasse N, Baillie LW, Paulsen IT, Nelson KE, et al. The Genome Sequence of Bacillus anthracis Ames and Comparison to Closely Related Bacteria. Nature 2003; 423:81-6.
    • (2003) Nature , vol.423 , pp. 81-86
    • Read, T.D.1    Peterson, S.N.2    Tourasse, N.3    Baillie, L.W.4    Paulsen, I.T.5    Nelson, K.E.6
  • 12
    • 2942614873 scopus 로고    scopus 로고
    • Identification of Anthrax Toxin Genes in a Bacillus cereus Associated with an Illness Resembling Inhalation Anthrax
    • Hoffmaster AR, Ravel J, Rasko DA, Chapman GD, Chute MD, Marston CK, et al. Identification of Anthrax Toxin Genes in a Bacillus cereus Associated with an Illness Resembling Inhalation Anthrax. Proc Natl Acad Sci USA 2004; 101:8449-54.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8449-8454
    • Hoffmaster, A.R.1    Ravel, J.2    Rasko, D.A.3    Chapman, G.D.4    Chute, M.D.5    Marston, C.K.6
  • 13
    • 0032760622 scopus 로고    scopus 로고
    • Molecular pathogenesis of Bacillus anthracis infection
    • Little SF, Ivins BE. Molecular pathogenesis of Bacillus anthracis infection. Microbes Infect 1999; 2:131-9.
    • (1999) Microbes Infect , vol.2 , pp. 131-139
    • Little, S.F.1    Ivins, B.E.2
  • 14
    • 0037099343 scopus 로고    scopus 로고
    • Effect of the Lower Molecular Capsule Released from the Cell Surface of Bacillus anthracis on the Pathogenesis of Anthrax
    • Makino SI, Watarai M, Cheun H-I, Shirahata T, Uchida I. Effect of the Lower Molecular Capsule Released from the Cell Surface of Bacillus anthracis on the Pathogenesis of Anthrax. J Infect Dis 2002; 186:227-33.
    • (2002) J Infect Dis , vol.186 , pp. 227-233
    • Makino, S.I.1    Watarai, M.2    Cheun, H.-I.3    Shirahata, T.4    Uchida, I.5
  • 16
    • 4444317796 scopus 로고    scopus 로고
    • Antitoxins: Novel Strategies to Target Agents of Bioterrorism
    • Rainey GJA, Young JAT. Antitoxins: Novel Strategies to Target Agents of Bioterrorism. Nat Rev Micro 2004; 2:721-6.
    • (2004) Nat Rev Micro , vol.2 , pp. 721-726
    • Rainey, G.J.A.1    Young, J.A.T.2
  • 18
    • 0002661972 scopus 로고
    • The Anthrax Toxin Complex
    • Alouf JE, Freer JH, eds, New York: Academic Press
    • Leppla SH. The Anthrax Toxin Complex. In Alouf JE, Freer JH, eds. Sourcebook of Bacterial Protein Toxins, New York: Academic Press 1991; 277-302.
    • (1991) Sourcebook of Bacterial Protein Toxins , pp. 277-302
    • Leppla, S.H.1
  • 19
    • 20144383121 scopus 로고    scopus 로고
    • Purified Bacillus anthracis Lethal Toxin Complex Formed in Vitro and During Infection Exhibits Functional and Biological Activity
    • Panchal RG, Halverson KM, Ribot W, Lane D, Kenny T, Abshire TG, et al. Purified Bacillus anthracis Lethal Toxin Complex Formed in Vitro and During Infection Exhibits Functional and Biological Activity. J Biol Chem 2005; 280:10834-9.
    • (2005) J Biol Chem , vol.280 , pp. 10834-10839
    • Panchal, R.G.1    Halverson, K.M.2    Ribot, W.3    Lane, D.4    Kenny, T.5    Abshire, T.G.6
  • 20
    • 0001731185 scopus 로고
    • Observations on Experimental Anthrax; Demonstration of a Specific Lethal Factor Produced in vivo by Bacillus anthracis
    • Smith H, Keppie J. Observations on Experimental Anthrax; Demonstration of a Specific Lethal Factor Produced in vivo by Bacillus anthracis. Nature 1954; 173:869-70.
    • (1954) Nature , vol.173 , pp. 869-870
    • Smith, H.1    Keppie, J.2
  • 22
    • 0032755353 scopus 로고    scopus 로고
    • Anthrax Lethal Factor Cleaves Mkk3 in Macrophages and Inhibits the Lps/Ifn-γ- Induced Release of NO and Tnfα
    • Pellizzari R, Guidi-Rontani C, Vitale G, Mock M, Montecucco C. Anthrax Lethal Factor Cleaves Mkk3 in Macrophages and Inhibits the Lps/Ifn-γ- Induced Release of NO and Tnfα. FEBS Letters 1999; 462:199-204.
    • (1999) FEBS Letters , vol.462 , pp. 199-204
    • Pellizzari, R.1    Guidi-Rontani, C.2    Vitale, G.3    Mock, M.4    Montecucco, C.5
  • 24
    • 31744441475 scopus 로고    scopus 로고
    • Nalp1b Controls Mouse Macrophage Susceptibility to Anthrax Lethal Toxin
    • Boyden ED, Dietrich WF. Nalp1b Controls Mouse Macrophage Susceptibility to Anthrax Lethal Toxin. Nat Gen 2006; 38:240-4.
    • (2006) Nat Gen , vol.38 , pp. 240-244
    • Boyden, E.D.1    Dietrich, W.F.2
  • 26
    • 0022973265 scopus 로고
    • Anthrax toxin blocks priming of neutrophils by lipopolysaccharide and by muramyl dipeptide
    • Wright GG, Mandell GL. Anthrax toxin blocks priming of neutrophils by lipopolysaccharide and by muramyl dipeptide. J Exp Med 1986; 164:1700-9.
    • (1986) J Exp Med , vol.164 , pp. 1700-1709
    • Wright, G.G.1    Mandell, G.L.2
  • 27
    • 1242351553 scopus 로고    scopus 로고
    • The roles of anthrax toxin in pathogenesis
    • Moayeri M, Leppla SH. The roles of anthrax toxin in pathogenesis. Curr Opin Microbiol 2004; 7:19-24.
    • (2004) Curr Opin Microbiol , vol.7 , pp. 19-24
    • Moayeri, M.1    Leppla, S.H.2
  • 28
    • 33846842333 scopus 로고    scopus 로고
    • Lethal and Edema Toxins in the Pathogenesis of Bacillus anthracis Septic Shock: Implications for Therapy
    • Sherer K, Li Y, Cui X, Eichacker PQ. Lethal and Edema Toxins in the Pathogenesis of Bacillus anthracis Septic Shock: Implications for Therapy. Am J Respir Crit Care Med 2007; 175:211-21.
    • (2007) Am J Respir Crit Care Med , vol.175 , pp. 211-221
    • Sherer, K.1    Li, Y.2    Cui, X.3    Eichacker, P.Q.4
  • 29
    • 0000883006 scopus 로고
    • Chemische und immunologische studien uber den mechanismus der milzbrandinfecktion und immunitat die chemische struktur der kapselsubstanz des milzbrandbazillus und der serolisch identischen spezifichen substanz des bacillus mesentericus. Z Immunitaetsforsch
    • Ivanovics G, Bruckner V. Chemische und immunologische studien uber den mechanismus der milzbrandinfecktion und immunitat die chemische struktur der kapselsubstanz des milzbrandbazillus und der serolisch identischen spezifichen substanz des bacillus mesentericus. Z Immunitaetsforsch. Experimental Therapeutics 1937; 90:304.
    • (1937) Experimental Therapeutics , vol.90 , pp. 304
    • Ivanovics, G.1    Bruckner, V.2
  • 30
    • 0032858381 scopus 로고    scopus 로고
    • Control of virulence gene expression in Bacillus anthracis
    • Hoffmaster AR, Koehler TM. Control of virulence gene expression in Bacillus anthracis. J Appl Microbiol 1999; 87:279-81.
    • (1999) J Appl Microbiol , vol.87 , pp. 279-281
    • Hoffmaster, A.R.1    Koehler, T.M.2
  • 31
    • 0035147581 scopus 로고    scopus 로고
    • Bacillus anthracis, a bug with attitude!
    • Baillie L, Read TD. Bacillus anthracis, a bug with attitude! Curr Opin Microbiol 2001; 4:78-81.
    • (2001) Curr Opin Microbiol , vol.4 , pp. 78-81
    • Baillie, L.1    Read, T.D.2
  • 32
    • 0035724284 scopus 로고    scopus 로고
    • The Incompatibility between the PlcR- and Atxa-Controlled Regulons May Have Selected a Nonsense Mutation in Bacillus anthracis
    • Mignot T, Mock M, Robichon D, Landier A, Lereclus D, Fouet A. The Incompatibility between the PlcR- and Atxa-Controlled Regulons May Have Selected a Nonsense Mutation in Bacillus anthracis. Mol Microbiol 2001; 42:1189-98.
    • (2001) Mol Microbiol , vol.42 , pp. 1189-1198
    • Mignot, T.1    Mock, M.2    Robichon, D.3    Landier, A.4    Lereclus, D.5    Fouet, A.6
  • 33
    • 15744404676 scopus 로고    scopus 로고
    • Role of superoxide in the germination of Bacillus anthracis endospores
    • Baillie L, Hibbs S, Tsai P, Cao GL, Rosen GM. Role of superoxide in the germination of Bacillus anthracis endospores. FEMS Microbiol Lett 2005; 245:33-8.
    • (2005) FEMS Microbiol Lett , vol.245 , pp. 33-38
    • Baillie, L.1    Hibbs, S.2    Tsai, P.3    Cao, G.L.4    Rosen, G.M.5
  • 34
    • 1242318694 scopus 로고    scopus 로고
    • Identification of proteins in the exosporium of Bacillus anthracis
    • Redmond C, Baillie LW, Hibbs S, Moir AJ, Moir A. Identification of proteins in the exosporium of Bacillus anthracis. Microbiology 2004; 150:355-63.
    • (2004) Microbiology , vol.150 , pp. 355-363
    • Redmond, C.1    Baillie, L.W.2    Hibbs, S.3    Moir, A.J.4    Moir, A.5
  • 35
    • 34547634437 scopus 로고    scopus 로고
    • Protective role of Bacillus anthracis exosporium in macrophage-mediated killing by nitric oxide
    • Weaver J, Kang TJ, Raines KW, Cao GL, Hibbs S, Tsai P, et al. Protective role of Bacillus anthracis exosporium in macrophage-mediated killing by nitric oxide. Infect Immun 2007; 75:3894-901.
    • (2007) Infect Immun , vol.75 , pp. 3894-3901
    • Weaver, J.1    Kang, T.J.2    Raines, K.W.3    Cao, G.L.4    Hibbs, S.5    Tsai, P.6
  • 36
    • 33645504807 scopus 로고    scopus 로고
    • Importance of nitric oxide synthase in the control of infection by Bacillus anthracis
    • Raines KW, Kang TJ, Hibbs S, Cao GL, Weaver J, Tsai P, et al. Importance of nitric oxide synthase in the control of infection by Bacillus anthracis. Infect Immun 2006; 74:2268-76.
    • (2006) Infect Immun , vol.74 , pp. 2268-2276
    • Raines, K.W.1    Kang, T.J.2    Hibbs, S.3    Cao, G.L.4    Weaver, J.5    Tsai, P.6
  • 38
    • 0002913857 scopus 로고    scopus 로고
    • Bacillus anthracis
    • Batt CA, Robinson RK, Patel PD, Eds. London: Academic Press
    • Baillie LWJ. Bacillus anthracis. In Encyclopaedia of Food Microbiology. Batt CA, Robinson RK, Patel PD, Eds. London: Academic Press 2000; 1:129-35.
    • (2000) Encyclopaedia of Food Microbiology , vol.1 , pp. 129-135
    • Baillie, L.W.J.1
  • 39
    • 33747114937 scopus 로고    scopus 로고
    • Past, imminent and future human medical countermeasures for anthrax
    • Baillie LW. Past, imminent and future human medical countermeasures for anthrax. J Appl Microbiol 2006; 101:594-606.
    • (2006) J Appl Microbiol , vol.101 , pp. 594-606
    • Baillie, L.W.1
  • 43
    • 0034785965 scopus 로고    scopus 로고
    • The development of new vaccines against Bacillus anthracis
    • Baillie L. The development of new vaccines against Bacillus anthracis. J Appl Microbiol 2001; 91:609-13.
    • (2001) J Appl Microbiol , vol.91 , pp. 609-613
    • Baillie, L.1
  • 44
    • 0036277812 scopus 로고    scopus 로고
    • Sequence analysis of the genes encoding for the major virulence factors of Bacillus anthracis vaccine strain 'Carbosap'
    • Adone R, Pasquali P, La Rosa G, Marianelli C, Muscillo M, Fasanella A, et al. Sequence analysis of the genes encoding for the major virulence factors of Bacillus anthracis vaccine strain 'Carbosap'. J Appl Microbiol 2002; 93:117-21.
    • (2002) J Appl Microbiol , vol.93 , pp. 117-121
    • Adone, R.1    Pasquali, P.2    La Rosa, G.3    Marianelli, C.4    Muscillo, M.5    Fasanella, A.6
  • 45
    • 0002753999 scopus 로고
    • The use of saponin spore vaccine for inoculation against anthrax in South Africa
    • Sterne M, Robinson EM, Nicol J. The use of saponin spore vaccine for inoculation against anthrax in South Africa. Onderstepoort J Vet Sci An Ind 1939; 12:279-302.
    • (1939) Onderstepoort J Vet Sci An Ind , vol.12 , pp. 279-302
    • Sterne, M.1    Robinson, E.M.2    Nicol, J.3
  • 46
    • 0021205725 scopus 로고
    • Anthrax: The disease in relation to vaccines
    • Hambleton P, Carman JA, Melling J. Anthrax: the disease in relation to vaccines. Vaccine 1984; 2:125-32.
    • (1984) Vaccine , vol.2 , pp. 125-132
    • Hambleton, P.1    Carman, J.A.2    Melling, J.3
  • 47
    • 0030927399 scopus 로고    scopus 로고
    • A recombinant Bacillus anthracis strain producing the Clostridium perfringens Ib component induces protection against iota toxins
    • Sirard JC, Weber M, Duflot E, Popoff MR, Mock M. A recombinant Bacillus anthracis strain producing the Clostridium perfringens Ib component induces protection against iota toxins. Infect Immun 1999; 65:2029-33.
    • (1999) Infect Immun , vol.65 , pp. 2029-2033
    • Sirard, J.C.1    Weber, M.2    Duflot, E.3    Popoff, M.R.4    Mock, M.5
  • 48
    • 0028175130 scopus 로고
    • Human live anthrax vaccine in the former USSR
    • Shlyakhov N, Rubinstein E. Human live anthrax vaccine in the former USSR. Vaccine 1994; 12:727-30.
    • (1994) Vaccine , vol.12 , pp. 727-730
    • Shlyakhov, N.1    Rubinstein, E.2
  • 49
    • 0037203927 scopus 로고    scopus 로고
    • Anthrax vaccine: Immunogenicity and safety of a dose-reduction, routechange comparison study in humans
    • Pittman PR, Kim-Ahn G, Pifat DY, Coonan K, Gibbs P, Little S, et al. Anthrax vaccine: immunogenicity and safety of a dose-reduction, routechange comparison study in humans. Vaccine 2002; 20:1412-20.
    • (2002) Vaccine , vol.20 , pp. 1412-1420
    • Pittman, P.R.1    Kim-Ahn, G.2    Pifat, D.Y.3    Coonan, K.4    Gibbs, P.5    Little, S.6
  • 50
    • 54849158900 scopus 로고    scopus 로고
    • Effects of a reduced dose schedule and intramuscular administration of anthrax vaccine adsorbed on immunogenicity and safety at 7 months: A randomized trial
    • Marano N, Plikaytis BD, Martin SW, Rose C, Semenova VA, Martin SK, et al. Effects of a reduced dose schedule and intramuscular administration of anthrax vaccine adsorbed on immunogenicity and safety at 7 months: a randomized trial. JAMA 2008; 300:1532-43.
    • (2008) JAMA , vol.300 , pp. 1532-1543
    • Marano, N.1    Plikaytis, B.D.2    Martin, S.W.3    Rose, C.4    Semenova, V.A.5    Martin, S.K.6
  • 51
    • 33845654330 scopus 로고    scopus 로고
    • Klinman DM, Xie H, Ivins BE. CpG Oligonucleotides Improve the Protective Immune Response Induced by the Licensed Anthrax Vaccine. Ann NY Acad Sci 2006; 1082:137-50.
    • Klinman DM, Xie H, Ivins BE. CpG Oligonucleotides Improve the Protective Immune Response Induced by the Licensed Anthrax Vaccine. Ann NY Acad Sci 2006; 1082:137-50.
  • 52
    • 77049158990 scopus 로고
    • Studies on a protective antigen produced in vitro from Bacillus anthracis: Medium and methods of production
    • Belton FC, Strange RE. Studies on a protective antigen produced in vitro from Bacillus anthracis: medium and methods of production. Brit J Exp Path 1954; 35:144-52.
    • (1954) Brit J Exp Path , vol.35 , pp. 144-152
    • Belton, F.C.1    Strange, R.E.2
  • 53
    • 75449114014 scopus 로고    scopus 로고
    • Broster MG, Hibbs SE. Protective Efficacy of Anthrax Vaccines against aerosol challenge. In Proceedings of the International Workshop on Anthrax, 11-12 April, 1989, Winchester UK. Salisbury Medical Bulletin 1990; 68:91-2.
    • Broster MG, Hibbs SE. Protective Efficacy of Anthrax Vaccines against aerosol challenge. In Proceedings of the International Workshop on Anthrax, 11-12 April, 1989, Winchester UK. Salisbury Medical Bulletin 1990; 68:91-2.
  • 55
    • 0000624090 scopus 로고
    • The use of anthrax antigen to immunise man and monkey
    • Darlow HM, Belton FC, Henderson DW. The use of anthrax antigen to immunise man and monkey. Lancet 1956; 11:476-9.
    • (1956) Lancet , vol.11 , pp. 476-479
    • Darlow, H.M.1    Belton, F.C.2    Henderson, D.W.3
  • 56
    • 34447525273 scopus 로고    scopus 로고
    • Immune response to two different dosing schedules of the anthrax vaccine precipitated (AVP) vaccine
    • Hepburn MJ, Dyson EH, Simpson AJH, Brenneman KE, Bailey N, Wilkinson L, et al. Immune response to two different dosing schedules of the anthrax vaccine precipitated (AVP) vaccine. Vaccine 2007; 25:6089-97.
    • (2007) Vaccine , vol.25 , pp. 6089-6097
    • Hepburn, M.J.1    Dyson, E.H.2    Simpson, A.J.H.3    Brenneman, K.E.4    Bailey, N.5    Wilkinson, L.6
  • 58
    • 15744404676 scopus 로고    scopus 로고
    • Role of superoxide in the germination of Bacillus anthracis endospores
    • Baillie L, Hibbs S, Tsai P, Cao GL, Rosen GM. Role of superoxide in the germination of Bacillus anthracis endospores. FEMS Microbiol Lett 2005; 245:33-8.
    • (2005) FEMS Microbiol Lett , vol.245 , pp. 33-38
    • Baillie, L.1    Hibbs, S.2    Tsai, P.3    Cao, G.L.4    Rosen, G.M.5
  • 61
    • 4544375374 scopus 로고    scopus 로고
    • A cationic lipid-formulated plasmid DNA vaccine confers sustained antibody-mediated protection against aerosolized anthrax spores
    • Hermanson G, Whitlow V, Parker S, Tonsky K, Rusalov D, Ferrari M, et al. A cationic lipid-formulated plasmid DNA vaccine confers sustained antibody-mediated protection against aerosolized anthrax spores. Proc Natl Acad Sci USA 2004; 101:13601-6.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 13601-13606
    • Hermanson, G.1    Whitlow, V.2    Parker, S.3    Tonsky, K.4    Rusalov, D.5    Ferrari, M.6
  • 63
    • 0037471407 scopus 로고    scopus 로고
    • Adverse medical events in British service personnel following anthrax vaccination
    • Enstone JE, Wale MC, Nguyen-Van-Tam JS, Pearson JC. Adverse medical events in British service personnel following anthrax vaccination. Vaccine 2003; 28:1348-5.
    • (2003) Vaccine , vol.28 , pp. 1348-1355
    • Enstone, J.E.1    Wale, M.C.2    Nguyen-Van-Tam, J.S.3    Pearson, J.C.4
  • 64
    • 0033537873 scopus 로고    scopus 로고
    • Subcutaneous versus intramuscular injection for booster DT vaccination of adolescents
    • Anders M, Carlsson RM, Granstroem M. Subcutaneous versus intramuscular injection for booster DT vaccination of adolescents. Vaccine 1999; 17:2067-72.
    • (1999) Vaccine , vol.17 , pp. 2067-2072
    • Anders, M.1    Carlsson, R.M.2    Granstroem, M.3
  • 65
    • 75449090233 scopus 로고    scopus 로고
    • Food and Drug Administration. New drug and biological drug products; evidence needed to demonstrate effectiveness of new drugs when human efficacy studies are not ethical or feasible. 21CFR 314 and 601. U.S. Food and Drug Administration. Rockville, MD: Department of Health and Human Services. 2002.
    • Food and Drug Administration. New drug and biological drug products; evidence needed to demonstrate effectiveness of new drugs when human efficacy studies are not ethical or feasible. 21CFR 314 and 601. U.S. Food and Drug Administration. Rockville, MD: Department of Health and Human Services. 2002.
  • 66
    • 0035859977 scopus 로고    scopus 로고
    • Passive transfer of protection against Bacillus anthracis infection in a murine model
    • Beedham RJ, Turnbull PC, Williamson ED. Passive transfer of protection against Bacillus anthracis infection in a murine model. Vaccine 2001; 19:4409-16.
    • (2001) Vaccine , vol.19 , pp. 4409-4416
    • Beedham, R.J.1    Turnbull, P.C.2    Williamson, E.D.3
  • 67
    • 0345096575 scopus 로고    scopus 로고
    • Defining a serological correlate of protection in rabbits for a recombinant anthrax vaccine
    • Little SF, Ivins BE, Fellows PF, Pitt ML, Norris SL, Andrews GP. Defining a serological correlate of protection in rabbits for a recombinant anthrax vaccine. Vaccine 2004; 22:422-30.
    • (2004) Vaccine , vol.22 , pp. 422-430
    • Little, S.F.1    Ivins, B.E.2    Fellows, P.F.3    Pitt, M.L.4    Norris, S.L.5    Andrews, G.P.6
  • 68
    • 55049095801 scopus 로고    scopus 로고
    • Towards a human oral vaccine for anthrax: The utility of a Salmonella typhi Ty21a-based prime-boost immunization strategy
    • Baillie LWJ, Rodriguez AL, Moore S, Atkins HS, Feng C, Nataro JP, Pasetti MF. Towards a human oral vaccine for anthrax: The utility of a Salmonella typhi Ty21a-based prime-boost immunization strategy. Vaccine 2008; 26:6083-91.
    • (2008) Vaccine , vol.26 , pp. 6083-6091
    • Baillie, L.W.J.1    Rodriguez, A.L.2    Moore, S.3    Atkins, H.S.4    Feng, C.5    Nataro, J.P.6    Pasetti, M.F.7
  • 69
    • 65449144795 scopus 로고    scopus 로고
    • Frequency and domain specificity of toxin-neutralizing paratopes in the human antibody response to anthrax vaccine adsorbed
    • Reason D, Liberato J, Sun J, Keitel W, Zhou J. Frequency and domain specificity of toxin-neutralizing paratopes in the human antibody response to anthrax vaccine adsorbed. Infect Immun 2009; 77:2030-5.
    • (2009) Infect Immun , vol.77 , pp. 2030-2035
    • Reason, D.1    Liberato, J.2    Sun, J.3    Keitel, W.4    Zhou, J.5
  • 70
    • 0036127006 scopus 로고    scopus 로고
    • Mucosal or parenteral administration of microsphere-associated Bacillus anthracis protective antigen protects against anthrax infection in mice
    • Flick-Smith HC, Eyles JE, Hebdon R, Waters EL, Beedham RJ, Stagg TJ, et al. Mucosal or parenteral administration of microsphere-associated Bacillus anthracis protective antigen protects against anthrax infection in mice. Infect Immun 2002; 70:2022-8.
    • (2002) Infect Immun , vol.70 , pp. 2022-2028
    • Flick-Smith, H.C.1    Eyles, J.E.2    Hebdon, R.3    Waters, E.L.4    Beedham, R.J.5    Stagg, T.J.6
  • 71
    • 34147139426 scopus 로고    scopus 로고
    • Oral administration of a Salmonella enterica-based vaccine expressing Bacillus anthracis protective antigen confers protection against aerosolized B. anthracis
    • Stokes MG, Titball RW, Neeson BN, Galen JE, Walker NJ, Stagg AJ, et al. Oral administration of a Salmonella enterica-based vaccine expressing Bacillus anthracis protective antigen confers protection against aerosolized B. anthracis. Infect Immunity 2007; 75:1827-34.
    • (2007) Infect Immunity , vol.75 , pp. 1827-1834
    • Stokes, M.G.1    Titball, R.W.2    Neeson, B.N.3    Galen, J.E.4    Walker, N.J.5    Stagg, A.J.6
  • 73
    • 0042232277 scopus 로고    scopus 로고
    • Alanine-scanning mutations in domain 4 of anthrax toxin protective antigen reveal residues important for binding to the cellular receptor and to a neutralizing monoclonal antibody
    • Rosovitz MJ, Schuck P, Varughese M, Chopra AP, Mehra V, Singh Y, et al. Alanine-scanning mutations in domain 4 of anthrax toxin protective antigen reveal residues important for binding to the cellular receptor and to a neutralizing monoclonal antibody. J Biol Chem 2003; 278:30936-44.
    • (2003) J Biol Chem , vol.278 , pp. 30936-30944
    • Rosovitz, M.J.1    Schuck, P.2    Varughese, M.3    Chopra, A.P.4    Mehra, V.5    Singh, Y.6
  • 74
    • 19544373976 scopus 로고    scopus 로고
    • The detection of protective antigen (PA) associated with spores of Bacillus anthracis and the effects of anti-PA antibodies on spore germination and macrophage interactions
    • Cote CK, Rossi CA, Kang AS, Morrow PR, Lee JS, Welkos SL. The detection of protective antigen (PA) associated with spores of Bacillus anthracis and the effects of anti-PA antibodies on spore germination and macrophage interactions. Microb Pathog 2005; 38:209-25.
    • (2005) Microb Pathog , vol.38 , pp. 209-225
    • Cote, C.K.1    Rossi, C.A.2    Kang, A.S.3    Morrow, P.R.4    Lee, J.S.5    Welkos, S.L.6
  • 77
    • 0030784575 scopus 로고    scopus 로고
    • Expression of cereolysine AB genes in Bacillus anthracis vaccine strain ensures protection against experimental hemolytic anthrax infection
    • Pomerantsev AP, Staritsin NA, Mockov YuV, Marinin LI. Expression of cereolysine AB genes in Bacillus anthracis vaccine strain ensures protection against experimental hemolytic anthrax infection. Vaccine 1997; 15:1846-50.
    • (1997) Vaccine , vol.15 , pp. 1846-1850
    • Pomerantsev, A.P.1    Staritsin, N.A.2    YuV, M.3    Marinin, L.I.4
  • 79
    • 54049105664 scopus 로고    scopus 로고
    • Effect of CpG Oligonucleotides on Vaccine-Induced B Cell Memory
    • Tross D, Klinman DM. Effect of CpG Oligonucleotides on Vaccine-Induced B Cell Memory J Immunol 2008; 181:5785-90.
    • (2008) J Immunol , vol.181 , pp. 5785-5790
    • Tross, D.1    Klinman, D.M.2
  • 80
    • 4644263749 scopus 로고    scopus 로고
    • Immune responses to Bacillus anthracis protective antigen in patients with bioterrorism-related cutaneous or inhalation anthrax
    • Quinn CP, Dull PM, Semenova V, Li H, Crotty S, Taylor TH, et al. Immune responses to Bacillus anthracis protective antigen in patients with bioterrorism-related cutaneous or inhalation anthrax. J Infect Dis 2004; 190:1228-36.
    • (2004) J Infect Dis , vol.190 , pp. 1228-1236
    • Quinn, C.P.1    Dull, P.M.2    Semenova, V.3    Li, H.4    Crotty, S.5    Taylor, T.H.6
  • 81
    • 33847203580 scopus 로고    scopus 로고
    • Cutting Edge: IFN-Producing CD4 T Lymphocytes Mediate Spore-Induced Immunity to Capsulated Bacillus anthracis
    • Glomski IJ, Corre JP, Mock M, Goossens PL. Cutting Edge: IFN-Producing CD4 T Lymphocytes Mediate Spore-Induced Immunity to Capsulated Bacillus anthracis. J Immunol 2007; 178:2646-50.
    • (2007) J Immunol , vol.178 , pp. 2646-2650
    • Glomski, I.J.1    Corre, J.P.2    Mock, M.3    Goossens, P.L.4
  • 83
    • 33745857009 scopus 로고    scopus 로고
    • Modulation of cytokine production and enhancement of cell viability by TLR7 and TLR9 ligands during anthrax infection of macrophages
    • Sabet M, Cottam HB, Guiney DG. Modulation of cytokine production and enhancement of cell viability by TLR7 and TLR9 ligands during anthrax infection of macrophages. FEMS Immunol Med Microbiol 2006; 47:369-79.
    • (2006) FEMS Immunol Med Microbiol , vol.47 , pp. 369-379
    • Sabet, M.1    Cottam, H.B.2    Guiney, D.G.3
  • 84
    • 27744603987 scopus 로고    scopus 로고
    • MyD88-dependent signaling contributes to protection following Bacillus anthracis spore challenge of mice: Implications for Toll-like receptor signaling
    • Hughes MA, Green CS, Lowchyj L, Lee GM, Grippe VK, Smith MF Jr, et al. MyD88-dependent signaling contributes to protection following Bacillus anthracis spore challenge of mice: implications for Toll-like receptor signaling. Infect Immun 2005; 73:7535-40.
    • (2005) Infect Immun , vol.73 , pp. 7535-7540
    • Hughes, M.A.1    Green, C.S.2    Lowchyj, L.3    Lee, G.M.4    Grippe, V.K.5    Smith Jr, M.F.6
  • 86
    • 33746058634 scopus 로고    scopus 로고
    • Immunogenicity and tolerance of ascending doses of a recombinant protective antigen (rPA102) anthrax vaccine: A randomized, double-blinded, controlled, multicenter trial
    • Gorse GJ, Keitel W, Keyserling H, Taylor DN, Lock M, Alves K, et al. Immunogenicity and tolerance of ascending doses of a recombinant protective antigen (rPA102) anthrax vaccine: a randomized, double-blinded, controlled, multicenter trial. Vaccine 2006; 24:5950-9.
    • (2006) Vaccine , vol.24 , pp. 5950-5959
    • Gorse, G.J.1    Keitel, W.2    Keyserling, H.3    Taylor, D.N.4    Lock, M.5    Alves, K.6
  • 87
    • 23944467589 scopus 로고    scopus 로고
    • Immunogenicity of recombinant protective antigen and efficacy against aerosol challenge with anthrax
    • Williamson ED, Hodgson I, Walker NJ, Topping AW, Duchars MG, Mott JM, et al. Immunogenicity of recombinant protective antigen and efficacy against aerosol challenge with anthrax. Infect Immun 2005; 73:5978-87.
    • (2005) Infect Immun , vol.73 , pp. 5978-5987
    • Williamson, E.D.1    Hodgson, I.2    Walker, N.J.3    Topping, A.W.4    Duchars, M.G.5    Mott, J.M.6
  • 88
    • 23944494081 scopus 로고    scopus 로고
    • Typhoid and paratyphoid fever
    • Bhan MK, Bahl R, Bhatnagar S. Typhoid and paratyphoid fever. Lancet 2005; 366:749-62.
    • (2005) Lancet , vol.366 , pp. 749-762
    • Bhan, M.K.1    Bahl, R.2    Bhatnagar, S.3
  • 90
    • 20044364761 scopus 로고    scopus 로고
    • Human-derived, plant-produced monoclonal antibody for the treatment of anthrax
    • Hull AK, Criscuolo CJ, Mett V, Groen H, Steeman W, Westra H, et al. Human-derived, plant-produced monoclonal antibody for the treatment of anthrax. Vaccine 2005; 23:2082-6.
    • (2005) Vaccine , vol.23 , pp. 2082-2086
    • Hull, A.K.1    Criscuolo, C.J.2    Mett, V.3    Groen, H.4    Steeman, W.5    Westra, H.6
  • 91
    • 28444439874 scopus 로고    scopus 로고
    • Plant-based vaccine: Mice immunized with chloroplastderived anthrax protective antigen survive anthrax lethal toxin challenge
    • Koya V, Moayeri M, Leppla SH, Daniell H. Plant-based vaccine: mice immunized with chloroplastderived anthrax protective antigen survive anthrax lethal toxin challenge. Infect Immun 2005; 73:8266-74.
    • (2005) Infect Immun , vol.73 , pp. 8266-8274
    • Koya, V.1    Moayeri, M.2    Leppla, S.H.3    Daniell, H.4
  • 93
    • 0033964153 scopus 로고    scopus 로고
    • Phase 2 clinical trial of attenuated Salmonella enterica serovar typhi oral live vector vaccine CVD 908-htrA in U.S. volunteers
    • Tacket CO, Sztein MB, Wasserman SS, Losonsky G, Kotloff KL, Wyant TL, et al. Phase 2 clinical trial of attenuated Salmonella enterica serovar typhi oral live vector vaccine CVD 908-htrA in U.S. volunteers. Infect Immun 2000; 68:1196-201.
    • (2000) Infect Immun , vol.68 , pp. 1196-1201
    • Tacket, C.O.1    Sztein, M.B.2    Wasserman, S.S.3    Losonsky, G.4    Kotloff, K.L.5    Wyant, T.L.6
  • 94
    • 21544474979 scopus 로고    scopus 로고
    • Oral spore vaccine based on live attenuated nontoxinogenic Bacillus anthracis expressing recombinant mutant protective antigen
    • Aloni-Grinstein R, Gat O, Altboum Z, Velan B, Cohen S, Shafferman A. Oral spore vaccine based on live attenuated nontoxinogenic Bacillus anthracis expressing recombinant mutant protective antigen. Infect Immun 2005; 73:4043-53.
    • (2005) Infect Immun , vol.73 , pp. 4043-4053
    • Aloni-Grinstein, R.1    Gat, O.2    Altboum, Z.3    Velan, B.4    Cohen, S.5    Shafferman, A.6
  • 95
    • 0032820970 scopus 로고    scopus 로고
    • Expression of the protective antigen of Bacillus anthracis by Lactobacillus casei: Towards the development of an oral vaccine against anthrax
    • Zegers ND, Kluter E, van Der Stap H, van Dura E, van Dalen P, Shaw M, Baillie L. Expression of the protective antigen of Bacillus anthracis by Lactobacillus casei: towards the development of an oral vaccine against anthrax. J Appl Microbiol 1999; 87:14-30.
    • (1999) J Appl Microbiol , vol.87 , pp. 14-30
    • Zegers, N.D.1    Kluter, E.2    van Der Stap, H.3    van Dura, E.4    van Dalen, P.5    Shaw, M.6    Baillie, L.7
  • 96
    • 0036842164 scopus 로고    scopus 로고
    • Salmonella vaccines for use in humans: Present and future perspectives
    • Garmory HS, Brown KA, Titball RW. Salmonella vaccines for use in humans: present and future perspectives. FEMS Microbiology Reviews 2002; 26:339-53.
    • (2002) FEMS Microbiology Reviews , vol.26 , pp. 339-353
    • Garmory, H.S.1    Brown, K.A.2    Titball, R.W.3
  • 97
    • 63149193407 scopus 로고    scopus 로고
    • Anthrax protective antigen delivered by Salmonella enterica serovar Typhi Ty21a protects mice from a lethal anthrax spore challenge
    • Osorio M, Wu Y, Singh S, Merkel TJ, Bhattacharyya S, Blake MS, Kopecko DJ. Anthrax protective antigen delivered by Salmonella enterica serovar Typhi Ty21a protects mice from a lethal anthrax spore challenge. Infect Immun 2009; 77:1475-82.
    • (2009) Infect Immun , vol.77 , pp. 1475-1482
    • Osorio, M.1    Wu, Y.2    Singh, S.3    Merkel, T.J.4    Bhattacharyya, S.5    Blake, M.S.6    Kopecko, D.J.7
  • 98
    • 58849119173 scopus 로고    scopus 로고
    • Mucosal immunization with attenuated Salmonella enterica serovar Typhi expressing protective antigen of anthrax toxin (PA83) primes monkeys for accelerated serum antibody responses to parenteral PA83 vaccine
    • Galen JE, Chinchilla M, Pasetti MF, Wang JY, Zhao L, Arciniega-Martinez I, et al. Mucosal immunization with attenuated Salmonella enterica serovar Typhi expressing protective antigen of anthrax toxin (PA83) primes monkeys for accelerated serum antibody responses to parenteral PA83 vaccine. J Infect Dis 2009; 199:326-35.
    • (2009) J Infect Dis , vol.199 , pp. 326-335
    • Galen, J.E.1    Chinchilla, M.2    Pasetti, M.F.3    Wang, J.Y.4    Zhao, L.5    Arciniega-Martinez, I.6
  • 99
    • 0842324614 scopus 로고    scopus 로고
    • Jump-starting the immune system: Prime-boosting comes of age
    • Woodland DL. Jump-starting the immune system: prime-boosting comes of age. Trends Immunol 2004; 25:98-104.
    • (2004) Trends Immunol , vol.25 , pp. 98-104
    • Woodland, D.L.1
  • 100
    • 36148931379 scopus 로고    scopus 로고
    • Heterologous prime-boost strategy to immunize very young infants against measles: Pre-clinical studies in rhesus macaques
    • Pasetti MF, Resendiz-Albor A, Ramirez K, Stout R, Papania M, Adams RJ, et al. Heterologous prime-boost strategy to immunize very young infants against measles: pre-clinical studies in rhesus macaques. Clin Pharmacol Ther 2007; 82:672-85.
    • (2007) Clin Pharmacol Ther , vol.82 , pp. 672-685
    • Pasetti, M.F.1    Resendiz-Albor, A.2    Ramirez, K.3    Stout, R.4    Papania, M.5    Adams, R.J.6
  • 101
    • 0037150485 scopus 로고    scopus 로고
    • Effect of nasal immunization with protective antigen of Bacillus anthracis on protective immune response against anthrax toxin
    • Gaur R, Gupta PK, Banerjea AC, Singh Y. Effect of nasal immunization with protective antigen of Bacillus anthracis on protective immune response against anthrax toxin. Vaccine 2002; 20:2836-9.
    • (2002) Vaccine , vol.20 , pp. 2836-2839
    • Gaur, R.1    Gupta, P.K.2    Banerjea, A.C.3    Singh, Y.4
  • 102
    • 0037514199 scopus 로고    scopus 로고
    • Effective mucosal immunity to anthrax: Neutralizing antibodies and Th cell responses following nasal immunization with protective antigen
    • Boyaka PN, Tafaro A, Fischer R, Leppla SH, Fujihashi K, McGhee JR. Effective mucosal immunity to anthrax: neutralizing antibodies and Th cell responses following nasal immunization with protective antigen. J Immunol 2003; 170:5636-43.
    • (2003) J Immunol , vol.170 , pp. 5636-5643
    • Boyaka, P.N.1    Tafaro, A.2    Fischer, R.3    Leppla, S.H.4    Fujihashi, K.5    McGhee, J.R.6
  • 103
    • 39049083470 scopus 로고    scopus 로고
    • Sloat BR, Shaker DS, Le UM, Cui Z. Nasal immunization with the mixture of PA63, LF, and a PGA conjugate induced strong antibody responses against all three antigens. FEMS Immunol Med Microbiol 2008; 52:169-79.
    • Sloat BR, Shaker DS, Le UM, Cui Z. Nasal immunization with the mixture of PA63, LF, and a PGA conjugate induced strong antibody responses against all three antigens. FEMS Immunol Med Microbiol 2008; 52:169-79.
  • 104
    • 52149108466 scopus 로고    scopus 로고
    • A single immunization with a dry powder anthrax vaccine protects rabbits against lethal aerosol challenge
    • Klas SD, Petrie CR, Warwood SJ, Williams MS, Olds CL, Stenz JP, et al. A single immunization with a dry powder anthrax vaccine protects rabbits against lethal aerosol challenge. Vaccine 2008; 26:5494-502.
    • (2008) Vaccine , vol.26 , pp. 5494-5502
    • Klas, S.D.1    Petrie, C.R.2    Warwood, S.J.3    Williams, M.S.4    Olds, C.L.5    Stenz, J.P.6
  • 107
    • 29644438356 scopus 로고    scopus 로고
    • Correlation between lethal toxin-neutralizing antibody titers and protection from intranasal challenge with Bacillus anthracis Ames strain spores in mice after transcutaneous immunization with recombinant anthrax protective antigen
    • Peachman KK, Rao M, Alving CR, Burge R, Leppla SH, Rao VB, et al. Correlation between lethal toxin-neutralizing antibody titers and protection from intranasal challenge with Bacillus anthracis Ames strain spores in mice after transcutaneous immunization with recombinant anthrax protective antigen. Infect Immun 2006; 74:794-7.
    • (2006) Infect Immun , vol.74 , pp. 794-797
    • Peachman, K.K.1    Rao, M.2    Alving, C.R.3    Burge, R.4    Leppla, S.H.5    Rao, V.B.6
  • 108
    • 33646943204 scopus 로고    scopus 로고
    • Topical application of Escherichia coli-vectored vaccine as a simple method for eliciting protective immunity
    • Zhang J, Shi Z, Kong FK, Jex E, Huang Z, Watt JM, et al. Topical application of Escherichia coli-vectored vaccine as a simple method for eliciting protective immunity. Infect Immun 2006; 74:3607-17.
    • (2006) Infect Immun , vol.74 , pp. 3607-3617
    • Zhang, J.1    Shi, Z.2    Kong, F.K.3    Jex, E.4    Huang, Z.5    Watt, J.M.6
  • 109
    • 19944429357 scopus 로고    scopus 로고
    • Protective immunization against inhalational anthrax: A comparison of minimally invasive delivery platforms
    • Mikszta JA, Sullivan VJ, Dean C, Waterston AM, Alarcon JB, Dekker JP, 3rd, et al. Protective immunization against inhalational anthrax: a comparison of minimally invasive delivery platforms. J Infect Dis 2005; 191:278-88.
    • (2005) J Infect Dis , vol.191 , pp. 278-288
    • Mikszta, J.A.1    Sullivan, V.J.2    Dean, C.3    Waterston, A.M.4    Alarcon, J.B.5    Dekker 3rd, J.P.6
  • 112
    • 68349143391 scopus 로고    scopus 로고
    • Keitel WA, Treanor JJ, El Sahly HM, Evans TG, Kopper S, Whitlow V. Evaluation of a plasmid DNA-based anthrax vaccine in rabbits, nonhuman primates and healthy adults. Hum Vaccine 2009; 5:Epub ahead of print.
    • Keitel WA, Treanor JJ, El Sahly HM, Evans TG, Kopper S, Whitlow V. Evaluation of a plasmid DNA-based anthrax vaccine in rabbits, nonhuman primates and healthy adults. Hum Vaccine 2009; 5:Epub ahead of print.
  • 114
    • 42949170542 scopus 로고    scopus 로고
    • Enhancement of antibody responses to Bacillus anthracis protective antigen domain IV by use of calreticulin as a chimeric molecular adjuvant
    • Park YS, Lee JH, Hung CF, Wu TC, Kim TW. Enhancement of antibody responses to Bacillus anthracis protective antigen domain IV by use of calreticulin as a chimeric molecular adjuvant. Infect Immun 2008; 76:1952-9.
    • (2008) Infect Immun , vol.76 , pp. 1952-1959
    • Park, Y.S.1    Lee, J.H.2    Hung, C.F.3    Wu, T.C.4    Kim, T.W.5
  • 115
    • 60549095969 scopus 로고    scopus 로고
    • Anthrax protective antigen administered by DNA vaccination to distinct subcellular locations potentiates humoral and cellular immune responses
    • Midha S, Bhatnagar R. Anthrax protective antigen administered by DNA vaccination to distinct subcellular locations potentiates humoral and cellular immune responses. Eur J Immunol 2009; 39:159-77.
    • (2009) Eur J Immunol , vol.39 , pp. 159-177
    • Midha, S.1    Bhatnagar, R.2
  • 116
    • 60549095969 scopus 로고    scopus 로고
    • Genetic immunization with GPI-anchored anthrax protective antigen raises combined CD1d- and MHC II-restricted antibody responses by natural killer T cell-mediated help
    • Midha S, Bhatnagar R. Genetic immunization with GPI-anchored anthrax protective antigen raises combined CD1d- and MHC II-restricted antibody responses by natural killer T cell-mediated help. Eur J Immunol 2009; 39:159-77.
    • (2009) Eur J Immunol , vol.39 , pp. 159-177
    • Midha, S.1    Bhatnagar, R.2
  • 117
    • 0344442277 scopus 로고    scopus 로고
    • Protective immunity evoked against anthrax lethal toxin after a single intramuscular administration of an adenovirus-based vaccine encoding humanized protective antigen
    • Tan YNR, Hackett NR, Boyer JL, Crystal RG. Protective immunity evoked against anthrax lethal toxin after a single intramuscular administration of an adenovirus-based vaccine encoding humanized protective antigen. Hum Gene Ther 2003; 14:1673-82.
    • (2003) Hum Gene Ther , vol.14 , pp. 1673-1682
    • Tan, Y.N.R.1    Hackett, N.R.2    Boyer, J.L.3    Crystal, R.G.4
  • 118
    • 33846207973 scopus 로고    scopus 로고
    • Multiagent vaccines vectored by Venezuelan Equine encephalitis virus replicon elicits immune responses to Marburg virus and protection against anthrax and botulinum neurotoxin in mice
    • Lee JS, Groebner JL, Hadjipanayis AG, Negley DL, Schmaljohn AL, Welkos SL, et al. Multiagent vaccines vectored by Venezuelan Equine encephalitis virus replicon elicits immune responses to Marburg virus and protection against anthrax and botulinum neurotoxin in mice. Vaccine 2006; 24:6886-92.
    • (2006) Vaccine , vol.24 , pp. 6886-6892
    • Lee, J.S.1    Groebner, J.L.2    Hadjipanayis, A.G.3    Negley, D.L.4    Schmaljohn, A.L.5    Welkos, S.L.6
  • 119
    • 36348937243 scopus 로고    scopus 로고
    • Adenovirus Toxicity and Tropism In Vivo: Not as Simple as A, B, C (or D, E, F)
    • Baker AH. Adenovirus Toxicity and Tropism In Vivo: Not as Simple as A, B, C (or D, E, F) Mol Ther 2007; 15:2061-2.
    • (2007) Mol Ther , vol.15 , pp. 2061-2062
    • Baker, A.H.1
  • 120
    • 25444443898 scopus 로고    scopus 로고
    • Induction of Protective Immunity to Anthrax Lethal Toxin with aNonhuman Primate Adenovirus-Based Vaccine in the Presence of Preexisting Anti-Human Adenovirus Immunity
    • Hashimoto M, Boyer JL, Hackett NR, Wilson JM, Crystal RG. Induction of Protective Immunity to Anthrax Lethal Toxin with aNonhuman Primate Adenovirus-Based Vaccine in the Presence of Preexisting Anti-Human Adenovirus Immunity. Infect Immun 2005; 73:6885-91.
    • (2005) Infect Immun , vol.73 , pp. 6885-6891
    • Hashimoto, M.1    Boyer, J.L.2    Hackett, N.R.3    Wilson, J.M.4    Crystal, R.G.5
  • 122
    • 0036151303 scopus 로고    scopus 로고
    • Anthrax spores make an essential contribution to vaccine efficacy
    • Brossier F, Levy M, Mock M. Anthrax spores make an essential contribution to vaccine efficacy. Infect Immun 2002; 70:661-4.
    • (2002) Infect Immun , vol.70 , pp. 661-664
    • Brossier, F.1    Levy, M.2    Mock, M.3
  • 123
    • 35649020232 scopus 로고    scopus 로고
    • Recombinant exosporium protein BclA of Bacillus anthracis is effective as a booster for mice primed with suboptimal amounts of protective antigen
    • Brahmbhatt TN, Darnell SC, Carvalho HM, Sanz P, Kang TJ, Bull RL, et al. Recombinant exosporium protein BclA of Bacillus anthracis is effective as a booster for mice primed with suboptimal amounts of protective antigen. Infect Immun 2007; 75:5240-7.
    • (2007) Infect Immun , vol.75 , pp. 5240-5247
    • Brahmbhatt, T.N.1    Darnell, S.C.2    Carvalho, H.M.3    Sanz, P.4    Kang, T.J.5    Bull, R.L.6
  • 124
    • 50049111406 scopus 로고    scopus 로고
    • Recombinant Bacillus anthracis spore proteins enhance protection of mice primed with suboptimal amounts of protective antigen
    • Cybulski RJ Jr, Sanz P, McDaniel D, Darnell S, Bull RL, O'Brien AD. Recombinant Bacillus anthracis spore proteins enhance protection of mice primed with suboptimal amounts of protective antigen. Vaccine 2008; 26:4927-39.
    • (2008) Vaccine , vol.26 , pp. 4927-4939
    • Cybulski Jr, R.J.1    Sanz, P.2    McDaniel, D.3    Darnell, S.4    Bull, R.L.5    O'Brien, A.D.6
  • 126
    • 33745617720 scopus 로고    scopus 로고
    • Search for Bacillus anthracis potential vaccine candidates by a functional genomic-serologic screen
    • Gat O, Grosfeld H, Ariel N, Inbar I, Zaide G, Broder Y, et al. Search for Bacillus anthracis potential vaccine candidates by a functional genomic-serologic screen. Infect Immun 2006; 74:3987-4001.
    • (2006) Infect Immun , vol.74 , pp. 3987-4001
    • Gat, O.1    Grosfeld, H.2    Ariel, N.3    Inbar, I.4    Zaide, G.5    Broder, Y.6
  • 127
    • 34249886795 scopus 로고    scopus 로고
    • Identification of in vivo-expressed immunogenic proteins by serological proteome analysis of the Bacillus anthracis secretome
    • Chitlaru T, Gat O, Grosfeld H, Inbar I, Gozlan Y, Shafferman A. Identification of in vivo-expressed immunogenic proteins by serological proteome analysis of the Bacillus anthracis secretome. Infect Immun 2007; 75:2841-52.
    • (2007) Infect Immun , vol.75 , pp. 2841-2852
    • Chitlaru, T.1    Gat, O.2    Grosfeld, H.3    Inbar, I.4    Gozlan, Y.5    Shafferman, A.6
  • 128
    • 75449100488 scopus 로고    scopus 로고
    • With the exception of PA none of the proteins were shown to be protective, unpublished data Baillie lab
    • With the exception of PA none of the proteins were shown to be protective. (unpublished data Baillie lab).
  • 129
    • 34648814056 scopus 로고    scopus 로고
    • Immunisation with anthrolysin O or a genetic toxoid protects against challenge with the toxin but not against Bacillus anthracis
    • Cowan GJ, Atkins HS, Johnson LK, Titball RW, Mitchell TJ. Immunisation with anthrolysin O or a genetic toxoid protects against challenge with the toxin but not against Bacillus anthracis. Vaccine 2007; 25:7197-205.
    • (2007) Vaccine , vol.25 , pp. 7197-7205
    • Cowan, G.J.1    Atkins, H.S.2    Johnson, L.K.3    Titball, R.W.4    Mitchell, T.J.5
  • 130
    • 34247899178 scopus 로고    scopus 로고
    • Bacillus anthracis anthrolysin O and three phospholipases C are functionally redundant in a murine model of inhalation anthrax
    • Heffernan BJ, Thomason B, Herring-Palmer A, Hanna P. Bacillus anthracis anthrolysin O and three phospholipases C are functionally redundant in a murine model of inhalation anthrax. FEMS Microbiol Lett 2007; 271:98-105.
    • (2007) FEMS Microbiol Lett , vol.271 , pp. 98-105
    • Heffernan, B.J.1    Thomason, B.2    Herring-Palmer, A.3    Hanna, P.4
  • 131
    • 63149158639 scopus 로고    scopus 로고
    • Killed but metabolically active Bacillus anthracis vaccines induce broad and protective immunity against anthrax
    • Skoble J, Beaber JW, Gao Y, Lovchik JA, Sower LE, Liu W, et al. Killed but metabolically active Bacillus anthracis vaccines induce broad and protective immunity against anthrax. Infect Immun 2009; 77:1649-63.
    • (2009) Infect Immun , vol.77 , pp. 1649-1663
    • Skoble, J.1    Beaber, J.W.2    Gao, Y.3    Lovchik, J.A.4    Sower, L.E.5    Liu, W.6
  • 132
    • 13644268506 scopus 로고    scopus 로고
    • Protective efficacy of a recombinant plague vaccine when co-administered with another sub-unit or live attenuated vaccine
    • Griffin K, Bedford R, Townson K, Phillpotts R, Funnell S, Morton M, et al Protective efficacy of a recombinant plague vaccine when co-administered with another sub-unit or live attenuated vaccine. FEMS Immunol Med Microbiol 2005; 43:425-30.
    • (2005) FEMS Immunol Med Microbiol , vol.43 , pp. 425-430
    • Griffin, K.1    Bedford, R.2    Townson, K.3    Phillpotts, R.4    Funnell, S.5    Morton, M.6
  • 134
    • 10744230259 scopus 로고    scopus 로고
    • Comparison of individual and combination DNA vaccines for B. anthracis, Ebola virus, Marburg virus and Venezuelan equine encephalitis virus
    • Riemenschneider J, Garrison A, Geisbert J, Jahrling P, Hevey M, Negley D, et al. Comparison of individual and combination DNA vaccines for B. anthracis, Ebola virus, Marburg virus and Venezuelan equine encephalitis virus. Vaccine 2003; 21:4071-80.
    • (2003) Vaccine , vol.21 , pp. 4071-4080
    • Riemenschneider, J.1    Garrison, A.2    Geisbert, J.3    Jahrling, P.4    Hevey, M.5    Negley, D.6
  • 135
    • 75449117258 scopus 로고    scopus 로고
    • US Provisional Patent Salmonella based oral vaccine for anthrax Inventor: Baillie LWJ 14.11.05
    • US Provisional Patent Salmonella based oral vaccine for anthrax Inventor: Baillie LWJ 14.11.05.
  • 136
    • 0041652361 scopus 로고    scopus 로고
    • Developing subunit immunogens using B and T cell epitopes and their constructs derived from the F1 antigen of Yersinia pestis using novel delivery vehicles
    • Sabhnani L, Manocha M, Sridevi K, Shashikiran D, Rayanade R, Rao DN. Developing subunit immunogens using B and T cell epitopes and their constructs derived from the F1 antigen of Yersinia pestis using novel delivery vehicles. FEMS Immunol Med Microbiol 2003; 38:215-29.
    • (2003) FEMS Immunol Med Microbiol , vol.38 , pp. 215-229
    • Sabhnani, L.1    Manocha, M.2    Sridevi, K.3    Shashikiran, D.4    Rayanade, R.5    Rao, D.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.