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Volumn 122, Issue 2, 2018, Pages 337-351

Circulating platelets as mediators of immunity, inflammation, and thrombosis

Author keywords

Blood platelets; Communication; Hemostasis; Immunity; Infection; Thrombosis

Indexed keywords

ADENOSINE DIPHOSPHATE; CD40 ANTIGEN; CD40 LIGAND; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; INTERLEUKIN 1BETA; MICRORNA; PADGEM PROTEIN; RANTES; SEROTONIN; THROMBOCYTE RECEPTOR; THROMBOXANE A2; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TRANSFORMING GROWTH FACTOR BETA; ANTITHROMBOCYTIC AGENT;

EID: 85044381414     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.117.310795     Document Type: Review
Times cited : (671)

References (136)
  • 1
    • 85013768269 scopus 로고    scopus 로고
    • London, United Kingdom Academic Press
    • Michelson AD. Platelets. London, United Kingdom: Academic Press; 2013.
    • (2013) Platelets
    • Michelson, A.D.1
  • 2
    • 84898853313 scopus 로고    scopus 로고
    • Overview of platelet physiology: Its hemostatic and nonhemostatic role in disease pathogenesis
    • Ghoshal K, Bhattacharyya M. Overview of platelet physiology: its hemostatic and nonhemostatic role in disease pathogenesis. Sci World J. 2014;2014:781857. doi: 10.1155/2014/781857.
    • (2014) Sci World J , vol.2014 , pp. 781857
    • Ghoshal, K.1    Bhattacharyya, M.2
  • 4
    • 84903209129 scopus 로고    scopus 로고
    • Emerging roles for platelets as immune and inflammatory cells
    • Morrell CN, Aggrey AA, Chapman LM, Modjeski KL. Emerging roles for platelets as immune and inflammatory cells. Blood. 2014;123:2759-2767. doi: 10.1182/blood-2013-11-462432.
    • (2014) Blood , vol.123 , pp. 2759-2767
    • Morrell, C.N.1    Aggrey, A.A.2    Chapman, L.M.3    Modjeski, K.L.4
  • 8
    • 25444437966 scopus 로고    scopus 로고
    • Platelets: Physiology and biochemistry
    • Jurk K, Kehrel BE. Platelets: physiology and biochemistry. Semin Thromb Hemost. 2005;31:381-392. doi: 10.1055/s-2005-916671.
    • (2005) Semin Thromb Hemost , vol.31 , pp. 381-392
    • Jurk, K.1    Kehrel, B.E.2
  • 9
    • 84871505285 scopus 로고    scopus 로고
    • Thrombosis as an intravascular effector of innate immunity
    • Engelmann B, Massberg S. Thrombosis as an intravascular effector of innate immunity. Nat Rev Immunol. 2013;13:34-45. doi: 10.1038/nri3345.
    • (2013) Nat Rev Immunol , vol.13 , pp. 34-45
    • Engelmann, B.1    Massberg, S.2
  • 11
    • 45949101608 scopus 로고    scopus 로고
    • The vessel wall and its interactions
    • Wagner DD, Frenette PS. The vessel wall and its interactions. Blood. 2008;111:5271-5281. doi: 10.1182/blood-2008-01-078204.
    • (2008) Blood , vol.111 , pp. 5271-5281
    • Wagner, D.D.1    Frenette, P.S.2
  • 13
    • 33644973012 scopus 로고    scopus 로고
    • Platelet-lymphocyte conjugation differs between lymphocyte subpopulations
    • Li N, Ji Q, Hjemdahl P. Platelet-lymphocyte conjugation differs between lymphocyte subpopulations. J Thromb Haemost. 2006;4:874-881. doi: 10.1111/j.1538-7836.2006.01817.x.
    • (2006) J Thromb Haemost , vol.4 , pp. 874-881
    • Li, N.1    Ji, Q.2    Hjemdahl, P.3
  • 14
    • 33645052482 scopus 로고    scopus 로고
    • Fibronectin-binding proteins of Staphylococcus aureus mediate activation of human platelets via fibrinogen and fibronectin bridges to integrin GPIIb/IIIa and IgG binding to the FcgammaRIIa receptor
    • Fitzgerald JR, Loughman A, Keane F, Brennan M, Knobel M, Higgins J, Visai L, Speziale P, Cox D, Foster TJ. Fibronectin-binding proteins of Staphylococcus aureus mediate activation of human platelets via fibrinogen and fibronectin bridges to integrin GPIIb/IIIa and IgG binding to the FcgammaRIIa receptor. Mol Microbiol. 2006;59:212-230. doi: 10.1111/j.1365-2958.2005.04922.x.
    • (2006) Mol Microbiol , vol.59 , pp. 212-230
    • Fitzgerald, J.R.1    Loughman, A.2    Keane, F.3    Brennan, M.4    Knobel, M.5    Higgins, J.6    Visai, L.7    Speziale, P.8    Cox, D.9    Foster, T.J.10
  • 15
    • 84903175342 scopus 로고    scopus 로고
    • Influenza virus H1N1 activates platelets through FcyRIIA signaling and thrombin generation
    • Boilard E, Paré G, Rousseau M, Cloutier N, Dubuc I, Lévesque T, Borgeat P, Flamand L. Influenza virus H1N1 activates platelets through FcyRIIA signaling and thrombin generation. Blood. 2014;123:2854-2863. doi: 10.1182/blood-2013-07-515536.
    • (2014) Blood , vol.123 , pp. 2854-2863
    • Boilard, E.1    Paré, G.2    Rousseau, M.3    Cloutier, N.4    Dubuc, I.5    Lévesque, T.6    Borgeat, P.7    Flamand, L.8
  • 18
    • 84868091620 scopus 로고    scopus 로고
    • Platelet factor 4 binding to lipid A of Gram-negative bacteria exposes PF4/heparin-like epitopes
    • Krauel K, Weber C, Brandt S, Zähringer U, Mamat U, Greinacher A, Hammerschmidt S. Platelet factor 4 binding to lipid A of Gram-negative bacteria exposes PF4/heparin-like epitopes. Blood. 2012;120:3345-3352. doi: 10.1182/blood-2012-06-434985.
    • (2012) Blood , vol.120 , pp. 3345-3352
    • Krauel, K.1    Weber, C.2    Brandt, S.3    Zähringer, U.4    Mamat, U.5    Greinacher, A.6    Hammerschmidt, S.7
  • 19
    • 79251583424 scopus 로고    scopus 로고
    • Platelet factor 4 binds to bacteria, [corrected] inducing antibodies cross-reacting with the major antigen in heparin-induced thrombocytopenia
    • Krauel K, Pötschke C, Weber C, Kessler W, Förll B, Ittermann T, Maier S, Hammerschmidt S, Bröker BM, Greinacher A. Platelet factor 4 binds to bacteria, [corrected] inducing antibodies cross-reacting with the major antigen in heparin-induced thrombocytopenia. Blood. 2011;117:1370-1378. doi: 10.1182/blood-2010-08-301424.
    • (2011) Blood , vol.117 , pp. 1370-1378
    • Krauel, K.1    Pötschke, C.2    Weber, C.3    Kessler, W.4    Förll, B.5    Ittermann, T.6    Maier, S.7    Hammerschmidt, S.8    Bröker, B.M.9    Greinacher, A.10
  • 22
    • 84876794338 scopus 로고    scopus 로고
    • Platelet induction of the acute-phase response is protective in murine experimental cerebral malaria
    • Aggrey AA, Srivastava K, Ture S, Field DJ, Morrell CN. Platelet induction of the acute-phase response is protective in murine experimental cerebral malaria. J Immunol. 2013;190:4685-4691. doi: 10.4049/jimmunol.1202672.
    • (2013) J Immunol , vol.190 , pp. 4685-4691
    • Aggrey, A.A.1    Srivastava, K.2    Ture, S.3    Field, D.J.4    Morrell, C.N.5
  • 23
    • 79960937640 scopus 로고    scopus 로고
    • A role for the chemokine RANTES in regulating CD8 T cell responses during chronic viral infection
    • Crawford A, Angelosanto JM, Nadwodny KL, Blackburn SD, Wherry EJ. A role for the chemokine RANTES in regulating CD8 T cell responses during chronic viral infection. PLoS Pathog. 2011;7:e1002098. doi: 10.1371/journal.ppat.1002098.
    • (2011) PLoS Pathog , vol.7 , pp. e1002098
    • Crawford, A.1    Angelosanto, J.M.2    Nadwodny, K.L.3    Blackburn, S.D.4    Wherry, E.J.5
  • 24
    • 84954431664 scopus 로고    scopus 로고
    • Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5
    • Alard JE, Ortega-Gomez A, Wichapong K, et al. Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5. Sci Transl Med. 2015;7:317ra196. doi: 10.1126/scitranslmed. aad5330.
    • (2015) Sci Transl Med , vol.7 , pp. 317ra196
    • Alard, J.E.1    Ortega-Gomez, A.2    Wichapong, K.3
  • 25
    • 70350244537 scopus 로고    scopus 로고
    • Platelet-derived transforming growth factor-beta down-regulates NKG2D thereby inhibiting natural killer cell antitumor reactivity
    • Kopp HG, Placke T, Salih HR. Platelet-derived transforming growth factor-beta down-regulates NKG2D thereby inhibiting natural killer cell antitumor reactivity. Cancer Res. 2009;69:7775-7783. doi: 10.1158/0008-5472.CAN-09-2123.
    • (2009) Cancer Res , vol.69 , pp. 7775-7783
    • Kopp, H.G.1    Placke, T.2    Salih, H.R.3
  • 26
    • 84905014848 scopus 로고    scopus 로고
    • Platelets guide the formation of early metastatic niches
    • Labelle M, Begum S, Hynes RO. Platelets guide the formation of early metastatic niches. Proc Natl Acad Sci USA. 2014;111:E3053-E3061. doi: 10.1073/pnas.1411082111.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. E3053-E3061
    • Labelle, M.1    Begum, S.2    Hynes, R.O.3
  • 27
    • 81255205399 scopus 로고    scopus 로고
    • Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis
    • Labelle M, Begum S, Hynes RO. Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis. Cancer Cell. 2011;20:576-590. doi: 10.1016/j.ccr.2011.09.009.
    • (2011) Cancer Cell , vol.20 , pp. 576-590
    • Labelle, M.1    Begum, S.2    Hynes, R.O.3
  • 29
    • 34147125008 scopus 로고    scopus 로고
    • Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor
    • León-Ponte M, Ahern GP, O'Connell PJ. Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor. Blood. 2007;109:3139-3146. doi: 10.1182/blood-2006-10-052787.
    • (2007) Blood , vol.109 , pp. 3139-3146
    • León-Ponte, M.1    Ahern, G.P.2    O'Connell, P.J.3
  • 30
    • 31544457592 scopus 로고    scopus 로고
    • A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells
    • O'Connell PJ, Wang X, Leon-Ponte M, Griffiths C, Pingle SC, Ahern GP. A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells. Blood. 2006;107:1010-1017. doi: 10.1182/blood-2005-07-2903.
    • (2006) Blood , vol.107 , pp. 1010-1017
    • O'Connell, P.J.1    Wang, X.2    Leon-Ponte, M.3    Griffiths, C.4    Pingle, S.C.5    Ahern, G.P.6
  • 31
    • 1542601104 scopus 로고    scopus 로고
    • Differential involvement of the P2Y1 and P2Y12 receptors in platelet procoagulant activity
    • Leon C, Ravanat C, Freund M, Cazenave JP, Gachet C. Differential involvement of the P2Y1 and P2Y12 receptors in platelet procoagulant activity. Arterioscler Thromb Vasc Biol. 2003;23:1941-1947. doi: 10.1161/01. ATV.0000092127.16125.E6.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1941-1947
    • Leon, C.1    Ravanat, C.2    Freund, M.3    Cazenave, J.P.4    Gachet, C.5
  • 32
    • 34249301744 scopus 로고    scopus 로고
    • Platelets recruit human dendritic cells via Mac-1/JAM-C interaction and modulate dendritic cell function in vitro
    • Langer HF, Daub K, Braun G, et al. Platelets recruit human dendritic cells via Mac-1/JAM-C interaction and modulate dendritic cell function in vitro. Arterioscler Thromb Vasc Biol. 2007;27:1463-1470. doi: 10.1161/ATVBAHA.107.141515.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1463-1470
    • Langer, H.F.1    Daub, K.2    Braun, G.3
  • 33
    • 0027071674 scopus 로고
    • Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis
    • Mueller BM, Reisfeld RA, Edgington TS, Ruf W. Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis. Proc Natl Acad Sci USA. 1992;89:11832-11836.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11832-11836
    • Mueller, B.M.1    Reisfeld, R.A.2    Edgington, T.S.3    Ruf, W.4
  • 34
    • 84905116699 scopus 로고    scopus 로고
    • Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis
    • Koupenova M, Vitseva O, MacKay CR, Beaulieu LM, Benjamin EJ, Mick E, Kurt-Jones EA, Ravid K, Freedman JE. Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis. Blood. 2014;124:791-802. doi: 10.1182/blood-2013-11-536003.
    • (2014) Blood , vol.124 , pp. 791-802
    • Koupenova, M.1    Vitseva, O.2    MacKay, C.R.3    Beaulieu, L.M.4    Benjamin, E.J.5    Mick, E.6    Kurt-Jones, E.A.7    Ravid, K.8    Freedman, J.E.9
  • 36
    • 26244438021 scopus 로고    scopus 로고
    • Endothelial cell activation by IL-1beta in the presence of fibrinogen requires alphavbeta3
    • Sahni A, Sahni SK, Francis CW. Endothelial cell activation by IL-1beta in the presence of fibrinogen requires alphavbeta3. Arterioscler Thromb Vasc Biol. 2005;25:2222-2227. doi: 10.1161/01.ATV.0000183605.27125.6f.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2222-2227
    • Sahni, A.1    Sahni, S.K.2    Francis, C.W.3
  • 37
    • 84860541893 scopus 로고    scopus 로고
    • Infections and inflammatory diseases as risk factors for venous thrombosis. A systematic review
    • Tichelaar YI, Kluin-Nelemans HJ, Meijer K. Infections and inflammatory diseases as risk factors for venous thrombosis. A systematic review. Thromb Haemost. 2012;107:827-837. doi: 10.1160/TH11-09-0611.
    • (2012) Thromb Haemost , vol.107 , pp. 827-837
    • Tichelaar, Y.I.1    Kluin-Nelemans, H.J.2    Meijer, K.3
  • 39
    • 84938079247 scopus 로고    scopus 로고
    • Infection and atherosclerosis development
    • Campbell LA, Rosenfeld ME. Infection and atherosclerosis development. Arch Med Res. 2015;46:339-350. doi: 10.1016/j.arcmed.2015.05.006.
    • (2015) Arch Med Res , vol.46 , pp. 339-350
    • Campbell, L.A.1    Rosenfeld, M.E.2
  • 40
    • 84876542457 scopus 로고    scopus 로고
    • Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network
    • Stalker TJ, Traxler EA, Wu J, Wannemacher KM, Cermignano SL, Voronov R, Diamond SL, Brass LF. Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network. Blood. 2013;121:1875-1885. doi: 10.1182/blood-2012-09-457739.
    • (2013) Blood , vol.121 , pp. 1875-1885
    • Stalker, T.J.1    Traxler, E.A.2    Wu, J.3    Wannemacher, K.M.4    Cermignano, S.L.5    Voronov, R.6    Diamond, S.L.7    Brass, L.F.8
  • 41
    • 84997428906 scopus 로고    scopus 로고
    • Regulation of platelet activation and coagulation and its role in vascular injury and arterial thrombosis
    • Tomaiuolo M, Brass LF, Stalker TJ. Regulation of platelet activation and coagulation and its role in vascular injury and arterial thrombosis. Interv Cardiol Clin. 2017;6:1-12. doi: 10.1016/j.iccl.2016.08.001.
    • (2017) Interv Cardiol Clin , vol.6 , pp. 1-12
    • Tomaiuolo, M.1    Brass, L.F.2    Stalker, T.J.3
  • 43
    • 84925690223 scopus 로고    scopus 로고
    • Glycobiology of platelet-endothelial cell interactions
    • Etulain J, Schattner M. Glycobiology of platelet-endothelial cell interactions. Glycobiology. 2014;24:1252-1259. doi: 10.1093/glycob/cwu056.
    • (2014) Glycobiology , vol.24 , pp. 1252-1259
    • Etulain, J.1    Schattner, M.2
  • 44
    • 0036139099 scopus 로고    scopus 로고
    • Fimbria-dependent activation of cell adhesion molecule expression in Porphyromonas gingivalis-infected endothelial cells
    • Khlgatian M, Nassar H, Chou HH, Gibson FC III, Genco CA. Fimbria-dependent activation of cell adhesion molecule expression in Porphyromonas gingivalis-infected endothelial cells. Infect Immun. 2002;70:257-267.
    • (2002) Infect Immun , vol.70 , pp. 257-267
    • Khlgatian, M.1    Nassar, H.2    Chou, H.H.3    Gibson, F.C.4    Genco, C.A.5
  • 45
    • 34848894877 scopus 로고    scopus 로고
    • Platelet-derived nitric oxide signaling and regulation
    • Gkaliagkousi E, Ritter J, Ferro A. Platelet-derived nitric oxide signaling and regulation. Circ Res. 2007;101:654-662. doi: 10.1161/CIRCRESAHA.107.158410.
    • (2007) Circ Res , vol.101 , pp. 654-662
    • Gkaliagkousi, E.1    Ritter, J.2    Ferro, A.3
  • 46
    • 23744515307 scopus 로고    scopus 로고
    • Escaping the nuclear confines: Signal-dependent pre-mRNA splicing in anucleate platelets
    • Denis MM, Tolley ND, Bunting M, et al. Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets. Cell. 2005;122:379-391. doi: 10.1016/j.cell.2005.06.015.
    • (2005) Cell , vol.122 , pp. 379-391
    • Denis, M.M.1    Tolley, N.D.2    Bunting, M.3
  • 48
    • 34748914299 scopus 로고    scopus 로고
    • Evolving functions of endothelial cells in inflammation
    • Pober JS, Sessa WC. Evolving functions of endothelial cells in inflammation. Nat Rev Immunol. 2007;7:803-815. doi: 10.1038/nri2171.
    • (2007) Nat Rev Immunol , vol.7 , pp. 803-815
    • Pober, J.S.1    Sessa, W.C.2
  • 49
    • 27644489137 scopus 로고    scopus 로고
    • Interleukin-1beta induced vascular permeability is dependent on induction of endothelial tissue factor (TF) activity
    • Puhlmann M, Weinreich DM, Farma JM, Carroll NM, Turner EM, Alexander HR Jr. Interleukin-1beta induced vascular permeability is dependent on induction of endothelial tissue factor (TF) activity. J Transl Med. 2005;3:37. doi: 10.1186/1479-5876-3-37.
    • (2005) J Transl Med , vol.3 , pp. 37
    • Puhlmann, M.1    Weinreich, D.M.2    Farma, J.M.3    Carroll, N.M.4    Turner, E.M.5    Alexander, H.R.6
  • 54
    • 34147188469 scopus 로고    scopus 로고
    • Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood
    • Clark SR, Ma AC, Tavener SA, et al. Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med. 2007;13:463-469. doi: 10.1038/nm1565.
    • (2007) Nat Med , vol.13 , pp. 463-469
    • Clark, S.R.1    Ma, A.C.2    Tavener, S.A.3
  • 56
    • 85030985905 scopus 로고    scopus 로고
    • TLR2 plays a key role in platelet hyperreactivity and accelerated thrombosis associated with hyperlipidemia
    • Biswas S, Zimman A, Gao D, Byzova TV, Podrez EA. TLR2 plays a key role in platelet hyperreactivity and accelerated thrombosis associated with hyperlipidemia. Circ Res. 2017;121:951-962. doi: 10.1161/CIRCRESAHA.117.311069.
    • (2017) Circ Res , vol.121 , pp. 951-962
    • Biswas, S.1    Zimman, A.2    Gao, D.3    Byzova, T.V.4    Podrez, E.A.5
  • 57
    • 61949483537 scopus 로고    scopus 로고
    • Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase
    • Blair P, Rex S, Vitseva O, Beaulieu L, Tanriverdi K, Chakrabarti S, Hayashi C, Genco CA, Iafrati M, Freedman JE. Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase. Circ Res. 2009;104:346-354. doi: 10.1161/CIRCRESAHA.108.185785.
    • (2009) Circ Res , vol.104 , pp. 346-354
    • Blair, P.1    Rex, S.2    Vitseva, O.3    Beaulieu, L.4    Tanriverdi, K.5    Chakrabarti, S.6    Hayashi, C.7    Genco, C.A.8    Iafrati, M.9    Freedman, J.E.10
  • 58
    • 84889605890 scopus 로고    scopus 로고
    • The toll-like receptor 2/1 (TLR2/1) complex initiates human platelet activation via the src/Syk/LAT/PLCy2 signalling cascade
    • F älker K, Klarström-Engström K, Bengtsson T, Lindahl TL, Grenegrd M. The toll-like receptor 2/1 (TLR2/1) complex initiates human platelet activation via the src/Syk/LAT/PLCy2 signalling cascade. Cell Signal. 2014;26:279-286. doi: 10.1016/j.cellsig.2013.11.011.
    • (2014) Cell Signal , vol.26 , pp. 279-286
    • Fälker, K.1    Klarström-Engström, K.2    Bengtsson, T.3    Lindahl, T.L.4    Grenegard, M.5
  • 59
    • 85027950667 scopus 로고    scopus 로고
    • Engagement of platelet toll-like receptor 9 by novel endogenous ligands promotes platelet hyperreactivity and thrombosis
    • Panigrahi S, Ma Y, Hong L, Gao D, West XZ, Salomon RG, Byzova TV, Podrez EA. Engagement of platelet toll-like receptor 9 by novel endogenous ligands promotes platelet hyperreactivity and thrombosis. Circ Res. 2013;112:103-112. doi: 10.1161/CIRCRESAHA.112.274241.
    • (2013) Circ Res , vol.112 , pp. 103-112
    • Panigrahi, S.1    Ma, Y.2    Hong, L.3    Gao, D.4    West, X.Z.5    Salomon, R.G.6    Byzova, T.V.7    Podrez, E.A.8
  • 61
    • 67649204120 scopus 로고    scopus 로고
    • Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway
    • Zhang G, Han J, Welch EJ, Ye RD, Voyno-Yasenetskaya TA, Malik AB, Du X, Li Z. Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway. J Immunol. 2009;182:7997-8004. doi: 10.4049/jimmunol.0802884.
    • (2009) J Immunol , vol.182 , pp. 7997-8004
    • Zhang, G.1    Han, J.2    Welch, E.J.3    Ye, R.D.4    Voyno-Yasenetskaya, T.A.5    Malik, A.B.6    Du, X.7    Li, Z.8
  • 64
    • 84873918079 scopus 로고    scopus 로고
    • Neutrophils recruited to sites of infection protect from virus challenge by releasing neutrophil extracellular traps
    • Jenne CN, Wong CH, Zemp FJ, McDonald B, Rahman MM, Forsyth PA, McFadden G, Kubes P. Neutrophils recruited to sites of infection protect from virus challenge by releasing neutrophil extracellular traps. Cell Host Microbe. 2013;13:169-180. doi: 10.1016/j.chom.2013.01.005.
    • (2013) Cell Host Microbe , vol.13 , pp. 169-180
    • Jenne, C.N.1    Wong, C.H.2    Zemp, F.J.3    McDonald, B.4    Rahman, M.M.5    Forsyth, P.A.6    McFadden, G.7    Kubes, P.8
  • 66
    • 84907693658 scopus 로고    scopus 로고
    • Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation
    • Boudreau LH, Duchez AC, Cloutier N, et al. Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation. Blood. 2014;124:2173-2183. doi: 10.1182/blood-2014-05-573543.
    • (2014) Blood , vol.124 , pp. 2173-2183
    • Boudreau, L.H.1    Duchez, A.C.2    Cloutier, N.3
  • 67
    • 84923838626 scopus 로고    scopus 로고
    • Virus-induced NETs-critical component of host defense or pathogenic mediator?
    • Jenne CN, Kubes P. Virus-induced NETs-critical component of host defense or pathogenic mediator? PLoS Pathog. 2015;11:e1004546. doi: 10.1371/journal.ppat.1004546.
    • (2015) PLoS Pathog , vol.11 , pp. e1004546
    • Jenne, C.N.1    Kubes, P.2
  • 68
    • 84902104685 scopus 로고    scopus 로고
    • Thrombosis: Tangled up in NETs
    • Martinod K, Wagner DD. Thrombosis: Tangled up in NETs. Blood. 2014;123:2768-2776. doi: 10.1182/blood-2013-10-463646.
    • (2014) Blood , vol.123 , pp. 2768-2776
    • Martinod, K.1    Wagner, D.D.2
  • 69
    • 84866175158 scopus 로고    scopus 로고
    • Neutrophil extracellular traps: Double-edged swords of innate immunity
    • Kaplan MJ, Radic M. Neutrophil extracellular traps: double-edged swords of innate immunity. J Immunol. 2012;189:2689-2695. doi: 10.4049/jimmunol.1201719.
    • (2012) J Immunol , vol.189 , pp. 2689-2695
    • Kaplan, M.J.1    Radic, M.2
  • 70
    • 0035949524 scopus 로고    scopus 로고
    • Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: Studies in baboons, human coronary intervention, and human acute myocardial infarction
    • Michelson AD, Barnard MR, Krueger LA, Valeri CR, Furman MI. Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: studies in baboons, human coronary intervention, and human acute myocardial infarction. Circulation. 2001;104:1533-1537.
    • (2001) Circulation , vol.104 , pp. 1533-1537
    • Michelson, A.D.1    Barnard, M.R.2    Krueger, L.A.3    Valeri, C.R.4    Furman, M.I.5
  • 71
    • 0037035461 scopus 로고    scopus 로고
    • Increased platelet binding to circulating monocytes in acute coronary syndromes
    • Sarma J, Laan CA, Alam S, Jha A, Fox KA, Dransfield I. Increased platelet binding to circulating monocytes in acute coronary syndromes. Circulation. 2002;105:2166-2171.
    • (2002) Circulation , vol.105 , pp. 2166-2171
    • Sarma, J.1    Laan, C.A.2    Alam, S.3    Jha, A.4    Fox, K.A.5    Dransfield, I.6
  • 76
    • 14944384692 scopus 로고    scopus 로고
    • Platelet P-selectin is required for pulmonary eosinophil and lymphocyte recruitment in a murine model of allergic inflammation
    • Pitchford SC, Momi S, Giannini S, Casali L, Spina D, Page CP, Gresele P. Platelet P-selectin is required for pulmonary eosinophil and lymphocyte recruitment in a murine model of allergic inflammation. Blood. 2005;105:2074-2081. doi: 10.1182/blood-2004-06-2282.
    • (2005) Blood , vol.105 , pp. 2074-2081
    • Pitchford, S.C.1    Momi, S.2    Giannini, S.3    Casali, L.4    Spina, D.5    Page, C.P.6    Gresele, P.7
  • 77
    • 34548137713 scopus 로고    scopus 로고
    • Human platelets can activate peripheral blood B cells and increase production of immunoglobulins
    • Cognasse F, Hamzeh-Cognasse H, Lafarge S, Chavarin P, Cogné M, Richard Y, Garraud O. Human platelets can activate peripheral blood B cells and increase production of immunoglobulins. Exp Hematol. 2007;35:1376-1387. doi: 10.1016/j.exphem.2007.05.021.
    • (2007) Exp Hematol , vol.35 , pp. 1376-1387
    • Cognasse, F.1    Hamzeh-Cognasse, H.2    Lafarge, S.3    Chavarin, P.4    Cogné, M.5    Richard, Y.6    Garraud, O.7
  • 78
    • 78649752133 scopus 로고    scopus 로고
    • Platelets enhance lymphocyte adhesion and infiltration into arterial thrombus
    • Hu H, Zhu L, Huang Z, Ji Q, Chatterjee M, Zhang W, Li N. Platelets enhance lymphocyte adhesion and infiltration into arterial thrombus. Thromb Haemost. 2010;104:1184-1192. doi: 10.1160/TH10-05-0308.
    • (2010) Thromb Haemost , vol.104 , pp. 1184-1192
    • Hu, H.1    Zhu, L.2    Huang, Z.3    Ji, Q.4    Chatterjee, M.5    Zhang, W.6    Li, N.7
  • 79
    • 0033559946 scopus 로고    scopus 로고
    • Lysis of tumor cells by natural killer cells in mice is impeded by platelets
    • Nieswandt B, Hafner M, Echtenacher B, Männel DN. Lysis of tumor cells by natural killer cells in mice is impeded by platelets. Cancer Res. 1999;59:1295-1300.
    • (1999) Cancer Res , vol.59 , pp. 1295-1300
    • Nieswandt, B.1    Hafner, M.2    Echtenacher, B.3    Männel, D.N.4
  • 80
    • 11144230059 scopus 로고    scopus 로고
    • Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell-mediated elimination of tumor cells
    • Palumbo JS, Talmage KE, Massari JV, La Jeunesse CM, Flick MJ, Kombrinck KW, Jirousková M, Degen JL. Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell-mediated elimination of tumor cells. Blood. 2005;105:178-185. doi: 10.1182/blood-2004-06-2272.
    • (2005) Blood , vol.105 , pp. 178-185
    • Palumbo, J.S.1    Talmage, K.E.2    Massari, J.V.3    La Jeunesse, C.M.4    Flick, M.J.5    Kombrinck, K.W.6    Jirousková, M.7    Degen, J.L.8
  • 82
    • 0343618701 scopus 로고    scopus 로고
    • Prominent role of P-selectin in the development of advanced atherosclerosis in ApoE-deficient mice
    • Dong ZM, Brown AA, Wagner DD. Prominent role of P-selectin in the development of advanced atherosclerosis in ApoE-deficient mice. Circulation. 2000;101:2290-2295.
    • (2000) Circulation , vol.101 , pp. 2290-2295
    • Dong, Z.M.1    Brown, A.A.2    Wagner, D.D.3
  • 83
    • 0037769793 scopus 로고    scopus 로고
    • Platelet P-selectin facilitates atherosclerotic lesion development
    • Burger PC, Wagner DD. Platelet P-selectin facilitates atherosclerotic lesion development. Blood. 2003;101:2661-2666. doi: 10.1182/blood-2002-07-2209.
    • (2003) Blood , vol.101 , pp. 2661-2666
    • Burger, P.C.1    Wagner, D.D.2
  • 85
    • 78549272749 scopus 로고    scopus 로고
    • Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis
    • Lievens D, Zernecke A, Seijkens T, et al. Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis. Blood. 2010;116:4317-4327. doi: 10.1182/blood-2010-01-261206.
    • (2010) Blood , vol.116 , pp. 4317-4327
    • Lievens, D.1    Zernecke, A.2    Seijkens, T.3
  • 87
    • 65849360502 scopus 로고    scopus 로고
    • Platelet alpha-granules: Basic biology and clinical correlates
    • Blair P, Flaumenhaft R. Platelet alpha-granules: basic biology and clinical correlates. Blood Rev. 2009;23:177-189. doi: 10.1016/j. blre.2009.04.001.
    • (2009) Blood Rev , vol.23 , pp. 177-189
    • Blair, P.1    Flaumenhaft, R.2
  • 88
    • 0036893696 scopus 로고    scopus 로고
    • Antimicrobial peptides from human platelets
    • Tang YQ, Yeaman MR, Selsted ME. Antimicrobial peptides from human platelets. Infect Immun. 2002;70:6524-6533.
    • (2002) Infect Immun , vol.70 , pp. 6524-6533
    • Tang, Y.Q.1    Yeaman, M.R.2    Selsted, M.E.3
  • 89
    • 75649135573 scopus 로고    scopus 로고
    • Platelets in defense against bacterial pathogens
    • Yeaman MR. Platelets in defense against bacterial pathogens. Cell Mol Life Sci. 2010;67:525-544. doi: 10.1007/s00018-009-0210-4.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 525-544
    • Yeaman, M.R.1
  • 90
    • 84919774344 scopus 로고    scopus 로고
    • Platelets and infection-An emerging role of platelets in viral infection
    • Assinger A. Platelets and infection-An emerging role of platelets in viral infection. Front Immunol. 2014;5:649. doi: 10.3389/fimmu.2014.00649.
    • (2014) Front Immunol , vol.5 , pp. 649
    • Assinger, A.1
  • 91
    • 33646854563 scopus 로고    scopus 로고
    • The interaction of bacterial pathogens with platelets
    • Fitzgerald JR, Foster TJ, Cox D. The interaction of bacterial pathogens with platelets. Nat Rev Microbiol. 2006;4:445-457. doi: 10.1038/nrmicro1425.
    • (2006) Nat Rev Microbiol , vol.4 , pp. 445-457
    • Fitzgerald, J.R.1    Foster, T.J.2    Cox, D.3
  • 93
    • 22644446001 scopus 로고    scopus 로고
    • Roles for fibrinogen, immunoglobulin and complement in platelet activation promoted by Staphylococcus aureus clumping factor A
    • Loughman A, Fitzgerald JR, Brennan MP, Higgins J, Downer R, Cox D, Foster TJ. Roles for fibrinogen, immunoglobulin and complement in platelet activation promoted by Staphylococcus aureus clumping factor A. Mol Microbiol. 2005;57:804-818. doi: 10.1111/j.1365-2958.2005.04731.x.
    • (2005) Mol Microbiol , vol.57 , pp. 804-818
    • Loughman, A.1    Fitzgerald, J.R.2    Brennan, M.P.3    Higgins, J.4    Downer, R.5    Cox, D.6    Foster, T.J.7
  • 94
    • 33748881470 scopus 로고    scopus 로고
    • Deadly plague versus mild-mannered TLR4
    • Dziarski R. Deadly plague versus mild-mannered TLR4. Nat Immunol. 2006;7:1017-1019. doi: 10.1038/ni1006-1017.
    • (2006) Nat Immunol , vol.7 , pp. 1017-1019
    • Dziarski, R.1
  • 97
    • 0020957024 scopus 로고
    • Association of herpes simplex virus with platelets of experimentally infected mice
    • Forghani B, Schmidt NJ. Association of herpes simplex virus with platelets of experimentally infected mice. Arch Virol. 1983;76:269-274.
    • (1983) Arch Virol , vol.76 , pp. 269-274
    • Forghani, B.1    Schmidt, N.J.2
  • 98
    • 0020063071 scopus 로고
    • Interaction between vaccinia virus and human blood platelets
    • Bik T, Sarov I, Livne A. Interaction between vaccinia virus and human blood platelets. Blood. 1982;59:482-487.
    • (1982) Blood , vol.59 , pp. 482-487
    • Bik, T.1    Sarov, I.2    Livne, A.3
  • 99
    • 0036625057 scopus 로고    scopus 로고
    • Host defense role of platelets: Engulfment of HIV and Staphylococcus aureus occurs in a specific subcellular compartment and is enhanced by platelet activation
    • Youssefian T, Drouin A, Massé JM, Guichard J, Cramer EM. Host defense role of platelets: engulfment of HIV and Staphylococcus aureus occurs in a specific subcellular compartment and is enhanced by platelet activation. Blood. 2002;99:4021-4029. doi: 10.1182/blood-2001-12-0191.
    • (2002) Blood , vol.99 , pp. 4021-4029
    • Youssefian, T.1    Drouin, A.2    Massé, J.M.3    Guichard, J.4    Cramer, E.M.5
  • 100
    • 1642383097 scopus 로고
    • Incorporation of influenza virus in human blood platelets in vitro. Electron microscopical observation
    • Danon D, Jerushalmy Z, De vries A. Incorporation of influenza virus in human blood platelets in vitro. Electron microscopical observation. Virology. 1959;9:719-722.
    • (1959) Virology , vol.9 , pp. 719-722
    • Danon, D.1    Jerushalmy, Z.2    De Vries, A.3
  • 103
    • 84922768348 scopus 로고    scopus 로고
    • Platelets interact with Coxsackieviruses B and have a critical role in the pathogenesis of virus-induced myocarditis
    • Negrotto S, Jaquenod de Giusti C, Rivadeneyra L, Ure AE, Mena HA, Schattner M, Gomez RM. Platelets interact with Coxsackieviruses B and have a critical role in the pathogenesis of virus-induced myocarditis. J Thromb Haemost. 2015;13:271-282. doi: 10.1111/jth.12782.
    • (2015) J Thromb Haemost , vol.13 , pp. 271-282
    • Negrotto, S.1    Jaquenod De Giusti, C.2    Rivadeneyra, L.3    Ure, A.E.4    Mena, H.A.5    Schattner, M.6    Gomez, R.M.7
  • 104
    • 0016712714 scopus 로고
    • The pathogenesis of vaccinia virus toxicity. II. An electron microscopic study
    • Sottnek HM, Campbell WG Jr, Cassel WA. The pathogenesis of vaccinia virus toxicity. II. An electron microscopic study. Lab Invest. 1975;33:522-532.
    • (1975) Lab Invest , vol.33 , pp. 522-532
    • Sottnek, H.M.1    Campbell, W.G.2    Cassel, W.A.3
  • 109
    • 84859426362 scopus 로고    scopus 로고
    • Detection of circulating platelet-monocyte complexes in persons infected with human immunodeficiency virus type-1
    • Singh MV, Davidson DC, Kiebala M, Maggirwar SB. Detection of circulating platelet-monocyte complexes in persons infected with human immunodeficiency virus type-1. J Virol Methods. 2012;181:170-176. doi: 10.1016/j.jviromet.2012.02.005.
    • (2012) J Virol Methods , vol.181 , pp. 170-176
    • Singh, M.V.1    Davidson, D.C.2    Kiebala, M.3    Maggirwar, S.B.4
  • 110
    • 80053989952 scopus 로고    scopus 로고
    • Monocyte-platelet interaction induces a pro-inflammatory phenotype in circulating monocytes
    • Passacquale G, Vamadevan P, Pereira L, Hamid C, Corrigall V, Ferro A. Monocyte-platelet interaction induces a pro-inflammatory phenotype in circulating monocytes. PLoS One. 2011;6:e25595. doi: 10.1371/journal. pone.0025595.
    • (2011) PLoS One , vol.6 , pp. e25595
    • Passacquale, G.1    Vamadevan, P.2    Pereira, L.3    Hamid, C.4    Corrigall, V.5    Ferro, A.6
  • 112
    • 84954526000 scopus 로고    scopus 로고
    • Microvesicle tissue factor activity and interleukin-8 levels are associated with mortality in patients with influenza A/H1N1 infection
    • Rondina MT, Tatsumi K, Bastarache JA, Mackman N. Microvesicle tissue factor activity and interleukin-8 levels are associated with mortality in patients with influenza A/H1N1 infection. Crit Care Med. 2016;44:e574-e578. doi: 10.1097/CCM.0000000000001584.
    • (2016) Crit Care Med , vol.44 , pp. e574-e578
    • Rondina, M.T.1    Tatsumi, K.2    Bastarache, J.A.3    Mackman, N.4
  • 115
    • 84863533856 scopus 로고    scopus 로고
    • Platelets and plateletlike particles mediate intercellular RNA transfer
    • Risitano A, Beaulieu LM, Vitseva O, Freedman JE. Platelets and plateletlike particles mediate intercellular RNA transfer. Blood. 2012;119:6288-6295. doi: 10.1182/blood-2011-12-396440.
    • (2012) Blood , vol.119 , pp. 6288-6295
    • Risitano, A.1    Beaulieu, L.M.2    Vitseva, O.3    Freedman, J.E.4
  • 117
    • 21544460952 scopus 로고    scopus 로고
    • Platelet microparticles: A transcellular delivery system for RANTES promoting monocyte recruitment on endothelium
    • Mause SF, von Hundelshausen P, Zernecke A, Koenen RR, Weber C. Platelet microparticles: A transcellular delivery system for RANTES promoting monocyte recruitment on endothelium. Arterioscler Thromb Vasc Biol. 2005;25:1512-1518. doi: 10.1161/01.ATV.0000170133.43608.37.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1512-1518
    • Mause, S.F.1    Von Hundelshausen, P.2    Zernecke, A.3    Koenen, R.R.4    Weber, C.5
  • 118
    • 77955432422 scopus 로고    scopus 로고
    • Platelet microparticles enhance the vasoregenerative potential of angiogenic early outgrowth cells after vascular injury
    • Mause SF, Ritzel E, Liehn EA, Hristov M, Bidzhekov K, Möller-Newen G, Soehnlein O, Weber C. Platelet microparticles enhance the vasoregenerative potential of angiogenic early outgrowth cells after vascular injury. Circulation. 2010;122:495-506. doi: 10.1161/CIRCULATIONAHA.109.909473.
    • (2010) Circulation , vol.122 , pp. 495-506
    • Mause, S.F.1    Ritzel, E.2    Liehn, E.A.3    Hristov, M.4    Bidzhekov, K.5    Möller-Newen, G.6    Soehnlein, O.7    Weber, C.8
  • 119
    • 84880466686 scopus 로고    scopus 로고
    • Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression
    • S1
    • Gidlöf O, van der Brug M, Ohman J, Gilje P, Olde B, Wahlestedt C, Erlinge D. Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression. Blood. 2013;121:3908, S1-3917, S1. doi: 10.1182/blood-2012-10-461798.
    • (2013) Blood , vol.121 , Issue.3908 , pp. S1-3917
    • Gidlöf, O.1    Van Der Brug, M.2    Ohman, J.3    Gilje, P.4    Olde, B.5    Wahlestedt, C.6    Erlinge, D.7
  • 121
    • 84884490899 scopus 로고    scopus 로고
    • Activated platelets can deliver mRNA regulatory Ago2 microRNA complexes to endothelial cells via microparticles
    • Laffont B, Corduan A, Plé H, Duchez AC, Cloutier N, Boilard E, Provost P. Activated platelets can deliver mRNA regulatory Ago2 microRNA complexes to endothelial cells via microparticles. Blood. 2013;122:253-261. doi: 10.1182/blood-2013-03-492801.
    • (2013) Blood , vol.122 , pp. 253-261
    • Laffont, B.1    Corduan, A.2    Plé, H.3    Duchez, A.C.4    Cloutier, N.5    Boilard, E.6    Provost, P.7
  • 122
    • 84928739972 scopus 로고    scopus 로고
    • MicroRNA-223 delivered by platelet-derived microvesicles promotes lung cancer cell invasion via targeting tumor suppressor EPB41L3
    • Liang H, Yan X, Pan Y, Wang Y, Wang N, Li L, Liu Y, Chen X, Zhang CY, Gu H, Zen K. MicroRNA-223 delivered by platelet-derived microvesicles promotes lung cancer cell invasion via targeting tumor suppressor EPB41L3. Mol Cancer. 2015;14:58. doi: 10.1186/s12943-015-0327-z.
    • (2015) Mol Cancer , vol.14 , pp. 58
    • Liang, H.1    Yan, X.2    Pan, Y.3    Wang, Y.4    Wang, N.5    Li, L.6    Liu, Y.7    Chen, X.8    Zhang, C.Y.9    Gu, H.10    Zen, K.11
  • 123
    • 85026750320 scopus 로고    scopus 로고
    • Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth
    • Michael JV, Wurtzel JGT, Mao GF, et al. Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth. Blood. 2017;130:567-580. doi: 10.1182/blood-2016-11-751099.
    • (2017) Blood , vol.130 , pp. 567-580
    • Michael, J.V.1    Jgt, W.2    Mao, G.F.3
  • 124
    • 38949218420 scopus 로고    scopus 로고
    • Critical role for the mitochondrial permeability transition pore and cyclophilin D in platelet activation and thrombosis
    • Jobe SM, Wilson KM, Leo L, Raimondi A, Molkentin JD, Lentz SR, Di Paola J. Critical role for the mitochondrial permeability transition pore and cyclophilin D in platelet activation and thrombosis. Blood. 2008;111:1257-1265. doi: 10.1182/blood-2007-05-092684.
    • (2008) Blood , vol.111 , pp. 1257-1265
    • Jobe, S.M.1    Wilson, K.M.2    Leo, L.3    Raimondi, A.4    Molkentin, J.D.5    Lentz, S.R.6    Di Paola, J.7
  • 125
    • 84886912940 scopus 로고    scopus 로고
    • Mitochondrially mediated integrin αiIbβ3 protein inactivation limits thrombus growth
    • Liu F, Gamez G, Myers DR, Clemmons W, Lam WA, Jobe SM. Mitochondrially mediated integrin αIIbβ3 protein inactivation limits thrombus growth. J Biol Chem. 2013;288:30672-30681. doi: 10.1074/jbc.M113.472688.
    • (2013) J Biol Chem , vol.288 , pp. 30672-30681
    • Liu, F.1    Gamez, G.2    Myers, D.R.3    Clemmons, W.4    Lam, W.A.5    Jobe, S.M.6
  • 128
    • 84868203266 scopus 로고    scopus 로고
    • Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure
    • Marques PE, Amaral SS, Pires DA, et al. Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure. Hepatology. 2012;56:1971-1982. doi: 10.1002/hep.25801.
    • (2012) Hepatology , vol.56 , pp. 1971-1982
    • Marques, P.E.1    Amaral, S.S.2    Pires, D.A.3
  • 132
    • 84869811636 scopus 로고    scopus 로고
    • Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases
    • György B, Szabó TG, Turiák L, et al. Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases. PLoS One. 2012;7:e49726. doi: 10.1371/journal. pone.0049726.
    • (2012) PLoS One , vol.7 , pp. e49726
    • György, B.1    Szabó, T.G.2    Turiák, L.3
  • 133
    • 85017381640 scopus 로고    scopus 로고
    • Association of dietary patterns with risk of colorectal cancer subtypes classified by Fusobacterium nucleatum in tumor tissue
    • Mehta RS, Nishihara R, Cao Y, et al. Association of dietary patterns with risk of colorectal cancer subtypes classified by Fusobacterium nucleatum in tumor tissue. JAMA Oncol. 2017;3:921-927. doi: 10.1001/jamaoncol.2016.6374.
    • (2017) JAMA Oncol , vol.3 , pp. 921-927
    • Mehta, R.S.1    Nishihara, R.2    Cao, Y.3
  • 134
    • 84962231546 scopus 로고    scopus 로고
    • A systems approach to hemostasis: 4. How hemostatic thrombi limit the loss of plasma-borne molecules from the microvasculature
    • Welsh JD, Muthard RW, Stalker TJ, Taliaferro JP, Diamond SL, Brass LF. A systems approach to hemostasis: 4. How hemostatic thrombi limit the loss of plasma-borne molecules from the microvasculature. Blood. 2016;127:1598-1605. doi: 10.1182/blood-2015-09-672188.
    • (2016) Blood , vol.127 , pp. 1598-1605
    • Welsh, J.D.1    Muthard, R.W.2    Stalker, T.J.3    Taliaferro, J.P.4    Diamond, S.L.5    Brass, L.F.6
  • 135
    • 0036522141 scopus 로고    scopus 로고
    • Oral glycoprotein IIb/IIIa receptor inhibitors in patients with cardiovascular disease: Why were the results so unfavourable
    • Leebeek FW, Boersma E, Cannon CP, van de Werf FJ, Simoons ML. Oral glycoprotein IIb/IIIa receptor inhibitors in patients with cardiovascular disease: why were the results so unfavourable. Eur Heart J. 2002;23:444-457. doi: 10.1053/euhj.2001.2751.
    • (2002) Eur Heart J , vol.23 , pp. 444-457
    • Leebeek, F.W.1    Boersma, E.2    Cannon, C.P.3    Van De Werf, F.J.4    Simoons, M.L.5


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