Lipopolysaccharide as trigger of platelet aggregation via eicosanoid Over-Production

Thrombosis and Haemostasis

Volumn 117, Issue 8, 2017, Pages 1558-1570

  Nocella, Cristina ^a,b   Carnevale, Roberto ^b   Bartimoccia, Simona ^b   Novo, Marta ^b   Cangemi, Roberto ^b   Pastori, Daniele ^b   Calvieri, Camilla ^b   Pignatelli, Pasquale ^b   Violi, Francesco ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Community acquired pneumonia; LPS; Oxidative stress; Platelet activation

Indexed keywords

ACETYLSALICYLIC ACID; CALCIUM; ENDOTOXIN; HYDROGEN PEROXIDE; ICOSANOID; LIPOPOLYSACCHARIDE; PROTEIN KINASE B; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SYNAPTOPHYSIN; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR; THROMBOXANE B2; TOLL LIKE RECEPTOR 4; 8-EPI-PROSTAGLANDIN F2ALPHA; CYBB PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUTROPHIL CYTOSOLIC FACTOR 1; PHOSPHOLIPASE A2 GROUP IV; PROSTAGLANDIN F2 ALPHA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TLR4 PROTEIN, HUMAN;

ADULT; AGED; APOPTOSIS; ARTICLE; CALCIUM MOBILIZATION; COMMUNITY ACQUIRED PNEUMONIA; ENZYME LINKED IMMUNOSORBENT ASSAY; EX VIVO STUDY; EXTRACTION; FEMALE; HUMAN; ICOSANOID METABOLISM; IN VIVO STUDY; MALE; MIDDLE AGED; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; BACTERIAL PNEUMONIA; BLOOD; CALCIUM SIGNALING; CASE CONTROL STUDY; COMMUNITY ACQUIRED INFECTION; DOSE RESPONSE; DRUG EFFECTS; ENZYME ACTIVATION; METABOLISM; MICROBIOLOGY; PHOSPHORYLATION; THROMBOCYTE; TIME FACTOR;

ADULT; AGED; BLOOD PLATELETS; CALCIUM SIGNALING; CASE-CONTROL STUDIES; COMMUNITY-ACQUIRED INFECTIONS; DINOPROST; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FEMALE; GROUP IV PHOSPHOLIPASES A2; HUMANS; HYDROGEN PEROXIDE; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; NADPH OXIDASE 2; NADPH OXIDASES; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLATELET AGGREGATION; PNEUMONIA, BACTERIAL; PROTO-ONCOGENE PROTEINS C-AKT; THROMBOXANE A2; TIME FACTORS; TOLL-LIKE RECEPTOR 4;

EID: 85026841482     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH16-11-0857     Document Type: Article

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