Microvesicle tissue factor activity and interleukin-8 levels are associated with mortality in patients with influenza A/H1N1 infection

Critical Care Medicine

Volumn 44, Issue 7, 2016, Pages e574-e578

  Rondina, Matthew T ^a,b   Tatsumi, Kohei ^c   Bastarache, Julie A ^d   Mackman, Nigel ^c  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

acute respiratory distress syndrome; influenza; interleukin 8; microvesicles; mortality; tissue factor; viral diseases

Indexed keywords

C REACTIVE PROTEIN; CD40 LIGAND; D DIMER; FIBRINOGEN; INTERLEUKIN 1; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; MICROVESICLE TISSUE FACTOR; PROCOAGULANT; THROMBIN ANTITHROMBIN COMPLEX; THROMBOPLASTIN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; CYTOKINE;

ADULT; APACHE; ARTICLE; BLOOD CLOTTING; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DISEASE SEVERITY; FEMALE; FIBRINOGEN BLOOD LEVEL; HUMAN; INFLAMMATION; INFLUENZA A (H1N1); MALE; MIDDLE AGED; MORTALITY; PILOT STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RESPIRATORY DISTRESS; SEPTIC SHOCK; BLOOD; CLINICAL TRIAL; INFLUENZA; INFLUENZA A VIRUS (H1N1); INTENSIVE CARE UNIT; METABOLISM; MICROVASCULATURE; MULTICENTER STUDY; PROGNOSIS;

ADULT; BIOMARKERS; CYTOKINES; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; INTENSIVE CARE UNITS; INTERLEUKIN-8; MICROVESSELS; PROGNOSIS; PROSPECTIVE STUDIES; THROMBOPLASTIN;

EID: 84954526000     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000001584     Document Type: Article

References (11)

1. Mulrennan S, Tempone SS, Ling IT, et al. Pandemic influenza (H1N1) 2009 pneumonia: CURB-65 score for predicting severity and nasopharyngeal sampling for diagnosis are unreliable. PLoS One 2010; 5:e12849
2. Bunce PE, High SM, Nadjafi M, et al. Pandemic H1N1 influenza infection and vascular thrombosis. Clin Infect Dis 2011; 52:e14-e17
3. Rondina MT, Brewster B, Grissom CK, et al. In vivo platelet activation in critically ill patients with primary 2009 influenza A(H1N1). Chest 2012; 141:1490-1495
4. Owens AP 3rd, Mackman N. Microparticles in hemostasis and thrombosis. Circ Res 2011; 108:1284-1297
5. Antoniak S, Mackman N. Multiple roles of the coagulation protease cascade during virus infection. Blood 2014; 123:2605-2613
6. Boilard E, Paré G, Rousseau M, et al. Influenza virus H1N1 activates platelets through Fc?RIIA signaling and thrombin generation. Blood 2014; 123:2854-2863
7. Khorana AA, Francis CW, Menzies KE, et al. Plasma tissue factor may be predictive of venous thromboembolism in pancreatic cancer. J Thromb Haemost 2008; 6:1983-1985
8. de Jong MD, Simmons CP, Thanh TT, et al. Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat Med 2006; 12:1203-1207
9. Meziani F, Delabranche X, Asfar P, et al. Bench-To-bedside review: Circulating microparticles-A new player in sepsis?. Crit Care 2010; 14:236
10. Morel O, Ohlmann P, Epailly E, et al. Endothelial cell activation contributes to the release of procoagulant microparticles during acute cardiac allograft rejection. J Heart Lung Transplant 2008; 27:38-45
11. Matsumoto H, Yamakawa K, Ogura H, et al. Enhanced expression of cell-specific surface antigens on endothelial microparticles in sepsis-induced disseminated intravascular coagulation. Shock 2015; 43:443-449