Platelets enhance lymphocyte adhesion and infiltration into arterial thrombus

Thrombosis and Haemostasis

Volumn 104, Issue 6, 2010, Pages 1184-1192

  Hu, Hu ^a   Zhu, Linjing ^a,b   Huang, Zhangsen ^a   Ji, Qiushang ^c   Chatterjee, Madhumita ^b   Zhang, Wei ^b   Li, Nailin ^a,b  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c SHANDONG UNIVERSITY   (China)

Author keywords

Arterial flow; Lymphocytes; Platelet lymphocyte conjugates; Platelets; Thrombosis

Indexed keywords

CD40 LIGAND; CELL ADHESION MOLECULE; COLLAGEN; FERROUS CHLORIDE; FIBRINOGEN RECEPTOR ANTAGONIST; PADGEM PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY BLOOD FLOW; ARTERY THROMBOSIS; ARTERY WALL; ARTICLE; B LYMPHOCYTE; BLOOD; CELL ADHESION; CELL INFILTRATION; FEMALE; HUMAN; HUMAN CELL; LAMINAR FLOW; LYMPHOCYTE; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; SHEAR RATE; T LYMPHOCYTE; THROMBOCYTE; THROMBOGENESIS;

ADULT; ANIMALS; ANTIBODIES, MONOCLONAL; ARTERIOLES; B-LYMPHOCYTES; BLOOD PLATELETS; CD40 LIGAND; CHLORIDES; COLLAGEN; DISEASE MODELS, ANIMAL; FEMALE; FERRIC COMPOUNDS; HUMANS; KILLER CELLS, NATURAL; LEUKOCYTE ROLLING; MALE; MESENTERY; MICE; MICE, INBRED C57BL; MIDDLE AGED; P-SELECTIN; PLATELET ADHESIVENESS; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; STRESS, MECHANICAL; T-LYMPHOCYTES; THROMBOSIS; TIME FACTORS; YOUNG ADULT;

EID: 78649752133     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH10-05-0308     Document Type: Article

References (29)

1. Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005; 352: 1685-1695.
2. Weber C. Platelets and chemokines in atherosclerosis: partners in crime. Circ Res 2005; 96: 612-616.
3. Davi G, Patrono C. Platelet activation and atherothrombosis. N Engl J Med 2007; 357: 2482-2494.
4. Langer HF, Gawaz M. Platelet-vessel wall interactions in atherosclerotic disease. Thromb Haemost 2008; 99: 480-486.
5. Jennings LK. Mechanisms of platelet activation: need for new strategies to protect against platelet-mediated atherothrombosis. Thromb Haemost 2009; 102: 248-257.
6. Muhlestein JB. Effect of antiplatelet therapy on inflammatory markers in atherothrombotic patients. Thromb Haemost 2010; 103: 71-82.
7. Zhou X, Nicoletti A, Elhage R, et al. Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice. Circulation 2000; 102: 2919-2922.
8. Caligiuri G, Nicoletti A, Poirier B, et al. Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice. J Clin Invest 2002; 109: 745-753.
9. Ait-Oufella H, Salomon BL, Potteaux S, et al. Natural regulatory T cells control the development of atherosclerosis in mice. Nat Med 2006; 12: 178-180. (Pubitemid 43214743)
10. Huo Y, Schober A, Forlow SB, et al. Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E. Nat Med 2003; 9: 61-67.
11. Massberg S, Brand K, Gruner S, et al. A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation. J Exp Med 2002; 196: 887-896.
12. Koenen RR, von Hundelshausen P, Nesmelova IV, et al. Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice. Nat Med 2009; 15: 97-103.
13. Li N. Platelet lymphocyte cross-talk. J Leukoc Biol 2008; 83: 1069-1078.
14. Lalor P, Nash GB. Adhesion of flowing leucocytes to immobilized platelets. Br J Haematol 1995; 89: 725-732.
15. Pitchford SC, Momi S, Giannini S, et al. Platelet P-selectin is required for pulmonary eosinophil and lymphocyte recruitment in a murine model of allergic inflammation. Blood 2005; 105: 2074-2081.
16. Rinder HM, Bonan JL, Rinder CS, et al. Dynamics of leukocyte-platelet adhesion in whole blood. Blood 1991; 78: 1730-1737.
17. Li N, Ji Q, Hjemdahl P. Platelet-lymphocyte conjugation differs between lymphocyte subpopulations. J Thromb Haemost 2006; 4: 874-881.
18. Li N, Goodall AH, Hjemdahl P. Efficient flow cytometric assay for platelet-leukocyte aggregates in whole blood using fluorescence signal triggering. Cytometry 1999; 35: 154-161.
19. Diacovo TG, Puri KD, Warnock RA, et al. Platelet-mediated lymphocyte delivery to high endothelial venules. Science 1996; 273: 252-255.
20. Elzey BD, Tian J, Jensen RJ, et al. Platelet-mediated modulation of adaptive immunity. A communication link between innate and adaptive immune compartments. Immunity 2003; 19: 9-19.
21. Gregg EO, Yarwood L, Wagstaffe MJ, et al. Immunomodulatory properties of platelet factor 4: prevention of concanavalin A suppressor-induction in vitro and augmentation of an antigen-specific delayed-type hypersensitivity response in vivo. Immunology 1990; 70: 230-234.
22. Liu CY, Battaglia M, Lee SH, et al. Platelet factor 4 differentially modulates CD4+CD25+ (regulatory) versus CD4+CD25- (nonregulatory) T cells. J Immunol 2005; 174: 2680-2686.
23. Hansson GK, Libby P, Schonbeck U, et al. Innate and adaptive immunity in the pathogenesis of atherosclerosis. Circ Res 2002; 91: 281-291.
24. Theilmeier G, Michiels C, Spaepen E, et al. Endothelial von Willebrand factor recruits platelets to atherosclerosis- prone sites in response to hypercholesterolemia. Blood 2002; 99: 4486-4493.
25. Hu H, Varon D, Hjemdahl P, et al. Platelet-leukocyte aggregation under shear stress: differential involvement of selectins and integrins. Thromb Haemost 2003; 90: 679-687.
26. Denis C, Methia N, Frenette PS, et al. A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. Proc Natl Acad Sci USA 1998; 95: 9524-9529.
27. van Gils JM, da Costa Martins PA, Mol A, et al. Transendothelial migration drives dissociation of platelet-monocyte complexes. Thromb Haemost 2008; 100: 271-279.
28. Shantsila E, Lip GY. The role of monocytes in thrombotic disorders. Insights from tissue factor, monocyte-platelet aggregates and novel mechanisms. Thromb Haemost 2009; 102: 916-924.
29. Ruggeri ZM. Old concepts and new developments in the study of platelet aggregation. J Clin Invest 2000; 105: 699-701.