Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis

Blood

Volumn 124, Issue 5, 2014, Pages 791-802

  Koupenova, Milka ^a,b   Vitseva, Olga ^a   MacKay, Christopher R ^a   Beaulieu, Lea M ^a   Benjamin, Emelia J ^b,c   Mick, Eric ^a   Kurt Jones, Evelyn A ^a   Ravid, Katya ^b   Freedman, Jane E ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BOSTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN RECEPTOR; PADGEM PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD; CELL SURFACE; CONTROLLED STUDY; ENCEPHALOMYOCARDITIS VIRUS; ENCEPHALOMYOCARDITIS VIRUS INFECTION; FEMALE; FLOW CYTOMETRY; GRANULOCYTE; HOST; HUMAN; IMMUNE RESPONSE; INTERNALIZATION; LEUKOCYTE ADHERENCE; LYMPHOCYTE SUBPOPULATION; MAJOR CLINICAL STUDY; MALE; MICROSCOPY; MONOCYTE; MORTALITY; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA VIRUS; SCANNING ELECTRON MICROSCOPY; SURVIVAL; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTOPENIA; THROMBOSIS; TRANSMISSION ELECTRON MICROSCOPY; VIRUS INFECTION; VIRUS PARTICLE;

ANIMALS; ANTIGENS, CD14; BLOOD PLATELETS; CARDIOVIRUS INFECTIONS; CELL DEGRANULATION; ENCEPHALOMYOCARDITIS VIRUS; FEMALE; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; NEUTROPHILS; PLATELET COUNT; SECRETORY VESICLES; THROMBOSIS; TOLL-LIKE RECEPTOR 7;

EID: 84905116699     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-11-536003     Document Type: Article

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