Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression

Blood

Volumn 121, Issue 19, 2013, Pages 3908-3917

  Gidlöf, Olof ^a   Van Der Brug, Marcel ^b,c   Öhman, Jenny ^a   Gilje, Patrik ^a   Olde, Björn ^a   Wahlestedt, Claes ^b   Erlinge, David ^a  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; MICRORNA; MICRORNA 185; MICRORNA 22; MICRORNA 320 B; MICRORNA 423 5 P; UNCLASSIFIED DRUG; ICAM1 PROTEIN, HUMAN; MIRN320 MICRORNA, HUMAN; TRANSCRIPTOME;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; RNA SEQUENCE; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; BLOOD; CASE CONTROL STUDY; CELL CULTURE; ENDOCYTOSIS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEART INFARCTION; MALE; METABOLISM; PHYSIOLOGY; THROMBOCYTE;

BLOOD PLATELETS; CASE-CONTROL STUDIES; CELLS, CULTURED; ENDOCYTOSIS; ENDOTHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MICRORNAS; MYOCARDIAL INFARCTION; PLATELET ACTIVATION; PLATELET AGGREGATION; TRANSCRIPTOME;

MLCS; MLOWN;

EID: 84880466686     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-10-461798     Document Type: Article

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