Characterization of the Polyspecific Transferase of Murine Type i Fatty Acid Synthase (FAS) and Implications for Polyketide Synthase (PKS) Engineering

ACS Chemical Biology

Volumn 13, Issue 3, 2018, Pages 723-732

  Rittner, Alexander ^a   Paithankar, Karthik S ^a   Huu, Khanh Vu ^a   Grininger, Martin ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A; ARGININE; FATTY ACID; FATTY ACID SYNTHASE; MALONIC ACID; MALONYL COENZYME A; POLYKETIDE; POLYKETIDE SYNTHASE; ACYLTRANSFERASE; TRANSFERASE;

ACYLATION; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME ENGINEERING; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME SUBSTRATE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; ANIMAL; CHEMISTRY; DRUG DEVELOPMENT; METABOLISM; MOUSE; PROCEDURES; PROTEIN ENGINEERING; SYNTHESIS;

ACYLATION; ACYLTRANSFERASES; ANIMALS; DRUG DISCOVERY; FATTY ACID SYNTHASE, TYPE I; MALONYL COENZYME A; MICE; POLYKETIDE SYNTHASES; POLYKETIDES; PROTEIN ENGINEERING; TRANSFERASES;

EID: 85044022614     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/acschembio.7b00718     Document Type: Article

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