-
1
-
-
84892414754
-
Functional promoter polymorphisms of NFKB1 influence susceptibility to the diffuse type of gastric cancer
-
Arisawa, T., Tahara, T., Shiroeda, H., Yamada, K., Nomura, T., Yamada, H., Hayashi, R., Matsunaga, K., Otsuka, T., Nakamura, M., Shimasaki, T., Toshikuni, N., Kawada, N., Shibata, T., Functional promoter polymorphisms of NFKB1 influence susceptibility to the diffuse type of gastric cancer. Oncol Rep. 30 (2013), 3013–3019.
-
(2013)
Oncol Rep.
, vol.30
, pp. 3013-3019
-
-
Arisawa, T.1
Tahara, T.2
Shiroeda, H.3
Yamada, K.4
Nomura, T.5
Yamada, H.6
Hayashi, R.7
Matsunaga, K.8
Otsuka, T.9
Nakamura, M.10
Shimasaki, T.11
Toshikuni, N.12
Kawada, N.13
Shibata, T.14
-
2
-
-
84924621296
-
An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo
-
Aubrey, B.J., Kelly, G.L., Kueh, A.J., Brennan, M.S., O'Connor, L., Milla, L., Wilcox, S., Tai, L., Strasser, A., Herold, M.J., An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo. Cell Rep. 10 (2015), 1422–1432.
-
(2015)
Cell Rep.
, vol.10
, pp. 1422-1432
-
-
Aubrey, B.J.1
Kelly, G.L.2
Kueh, A.J.3
Brennan, M.S.4
O'Connor, L.5
Milla, L.6
Wilcox, S.7
Tai, L.8
Strasser, A.9
Herold, M.J.10
-
3
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer, J.R., Tykodi, S.S., Chow, L.Q., Hwu, W.J., Topalian, S.L., Hwu, P., Drake, C.G., Camacho, L.H., Kauh, J., Odunsi, K., et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N. Engl. J. Med. 366 (2012), 2455–2465.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
Drake, C.G.7
Camacho, L.H.8
Kauh, J.9
Odunsi, K.10
-
4
-
-
84907270779
-
Comprehensive molecular characterization of gastric adenocarcinoma
-
Cancer Genome Atlas Research Network. Comprehensive molecular characterization of gastric adenocarcinoma. Nature 513 (2014), 202–209.
-
(2014)
Nature
, vol.513
, pp. 202-209
-
-
-
5
-
-
33748756806
-
NF-kappaB1 (p50) homodimers differentially regulate pro- and anti-inflammatory cytokines in macrophages
-
Cao, S., Zhang, X., Edwards, J.P., Mosser, D.M., NF-kappaB1 (p50) homodimers differentially regulate pro- and anti-inflammatory cytokines in macrophages. J. Biol. Chem. 281 (2006), 26041–26050.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 26041-26050
-
-
Cao, S.1
Zhang, X.2
Edwards, J.P.3
Mosser, D.M.4
-
6
-
-
84898921083
-
STAT3 Target Genes Relevant to Human Cancers
-
Carpenter, R.L., Lo, H.W., STAT3 Target Genes Relevant to Human Cancers. Cancers (Basel) 6 (2014), 897–925.
-
(2014)
Cancers (Basel)
, vol.6
, pp. 897-925
-
-
Carpenter, R.L.1
Lo, H.W.2
-
7
-
-
84923865928
-
The NFKB1 polymorphism (rs4648068) is associated with the cell proliferation and motility in gastric cancer
-
Chen, Y., Lu, R., Zheng, H., Xiao, R., Feng, J., Wang, H., Gao, X., Guo, L., The NFKB1 polymorphism (rs4648068) is associated with the cell proliferation and motility in gastric cancer. BMC Gastroenterol., 15, 2015, 21.
-
(2015)
BMC Gastroenterol.
, vol.15
, pp. 21
-
-
Chen, Y.1
Lu, R.2
Zheng, H.3
Xiao, R.4
Feng, J.5
Wang, H.6
Gao, X.7
Guo, L.8
-
8
-
-
79952173562
-
The specificity of innate immune responses is enforced by repression of interferon response elements by NF-κB p50
-
Cheng, C.S., Feldman, K.E., Lee, J., Verma, S., Huang, D.B., Huynh, K., Chang, M., Ponomarenko, J.V., Sun, S.C., Benedict, C.A., et al. The specificity of innate immune responses is enforced by repression of interferon response elements by NF-κB p50. Sci. Signal., 4, 2011, ra11.
-
(2011)
Sci. Signal.
, vol.4
, pp. ra11
-
-
Cheng, C.S.1
Feldman, K.E.2
Lee, J.3
Verma, S.4
Huang, D.B.5
Huynh, K.6
Chang, M.7
Ponomarenko, J.V.8
Sun, S.C.9
Benedict, C.A.10
-
9
-
-
0027065034
-
Human gastric carcinogenesis: a multistep and multifactorial process–First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention
-
Correa, P., Human gastric carcinogenesis: a multistep and multifactorial process–First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res. 52 (1992), 6735–6740.
-
(1992)
Cancer Res.
, vol.52
, pp. 6735-6740
-
-
Correa, P.1
-
10
-
-
85015622116
-
NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells
-
de Valle, E., Grigoriadis, G., O'Reilly, L.A., Willis, S.N., Maxwell, M.J., Corcoran, L.M., Tsantikos, E., Cornish, J.K., Fairfax, K.A., Vasanthakumar, A., et al. NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells. J. Exp. Med. 213 (2016), 621–641.
-
(2016)
J. Exp. Med.
, vol.213
, pp. 621-641
-
-
de Valle, E.1
Grigoriadis, G.2
O'Reilly, L.A.3
Willis, S.N.4
Maxwell, M.J.5
Corcoran, L.M.6
Tsantikos, E.7
Cornish, J.K.8
Fairfax, K.A.9
Vasanthakumar, A.10
-
11
-
-
17744371331
-
TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway
-
Dumitru, C.D., Ceci, J.D., Tsatsanis, C., Kontoyiannis, D., Stamatakis, K., Lin, J.H., Patriotis, C., Jenkins, N.A., Copeland, N.G., Kollias, G., Tsichlis, P.N., TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway. Cell 103 (2000), 1071–1083.
-
(2000)
Cell
, vol.103
, pp. 1071-1083
-
-
Dumitru, C.D.1
Ceci, J.D.2
Tsatsanis, C.3
Kontoyiannis, D.4
Stamatakis, K.5
Lin, J.H.6
Patriotis, C.7
Jenkins, N.A.8
Copeland, N.G.9
Kollias, G.10
Tsichlis, P.N.11
-
12
-
-
77955850955
-
The NF-kappaB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes
-
Elsharkawy, A.M., Oakley, F., Lin, F., Packham, G., Mann, D.A., Mann, J., The NF-kappaB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes. J. Hepatol. 53 (2010), 519–527.
-
(2010)
J. Hepatol.
, vol.53
, pp. 519-527
-
-
Elsharkawy, A.M.1
Oakley, F.2
Lin, F.3
Packham, G.4
Mann, D.A.5
Mann, J.6
-
13
-
-
0033935241
-
Outbred mice with long-term Helicobacter felis infection develop both gastric lymphoid tissue and glandular hyperplastic lesions
-
Ferrero, R.L., Avé P., Radcliff, F.J., Labigne, A., Huerre, M.R., Outbred mice with long-term Helicobacter felis infection develop both gastric lymphoid tissue and glandular hyperplastic lesions. J. Pathol. 191 (2000), 333–340.
-
(2000)
J. Pathol.
, vol.191
, pp. 333-340
-
-
Ferrero, R.L.1
Avé, P.2
Radcliff, F.J.3
Labigne, A.4
Huerre, M.R.5
-
14
-
-
85026806356
-
KEYNOTE-059 cohort 1: Efficacy and safety of pembrolizumab (pembro) monotherapy in patients with previously treated advanced gastric cancer
-
4003–4003
-
Fuchs, C.S., Doi, T., Jang, R.W.J., Muro, K., Satoh, T., Machado, M., et al. KEYNOTE-059 cohort 1: Efficacy and safety of pembrolizumab (pembro) monotherapy in patients with previously treated advanced gastric cancer. J. Clin. Oncol., 35, 2017 4003–4003.
-
(2017)
J. Clin. Oncol.
, vol.35
-
-
Fuchs, C.S.1
Doi, T.2
Jang, R.W.J.3
Muro, K.4
Satoh, T.5
Machado, M.6
-
15
-
-
84876234459
-
TPL2 kinase is a suppressor of lung carcinogenesis
-
Gkirtzimanaki, K., Gkouskou, K.K., Oleksiewicz, U., Nikolaidis, G., Vyrla, D., Liontos, M., Pelekanou, V., Kanellis, D.C., Evangelou, K., Stathopoulos, E.N., et al. TPL2 kinase is a suppressor of lung carcinogenesis. Proc. Natl. Acad. Sci. USA 110 (2013), E1470–E1479.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. E1470-E1479
-
-
Gkirtzimanaki, K.1
Gkouskou, K.K.2
Oleksiewicz, U.3
Nikolaidis, G.4
Vyrla, D.5
Liontos, M.6
Pelekanou, V.7
Kanellis, D.C.8
Evangelou, K.9
Stathopoulos, E.N.10
-
16
-
-
0031899363
-
Proteins encoded by the cag pathogenicity island of Helicobacter pylori are required for NF-kappaB activation
-
Glocker, E., Lange, C., Covacci, A., Bereswill, S., Kist, M., Pahl, H.L., Proteins encoded by the cag pathogenicity island of Helicobacter pylori are required for NF-kappaB activation. Infect. Immun. 66 (1998), 2346–2348.
-
(1998)
Infect. Immun.
, vol.66
, pp. 2346-2348
-
-
Glocker, E.1
Lange, C.2
Covacci, A.3
Bereswill, S.4
Kist, M.5
Pahl, H.L.6
-
17
-
-
0028154853
-
The subunit composition of NF-kappa B complexes changes during B-cell development
-
Grumont, R.J., Gerondakis, S., The subunit composition of NF-kappa B complexes changes during B-cell development. Cell Growth Differ. 5 (1994), 1321–1331.
-
(1994)
Cell Growth Differ.
, vol.5
, pp. 1321-1331
-
-
Grumont, R.J.1
Gerondakis, S.2
-
18
-
-
0027669329
-
Rel/NF-kB nuclear complexes that bind kB sites in the murine C-Rel promoter are required for constitutive C-Rel transcription in B-cells
-
Grumont, R.J., Richardson, I.B., Gaff, C., Gerondakis, S., Rel/NF-kB nuclear complexes that bind kB sites in the murine C-Rel promoter are required for constitutive C-Rel transcription in B-cells. Cell Growth Differ. 4 (1993), 731–743.
-
(1993)
Cell Growth Differ.
, vol.4
, pp. 731-743
-
-
Grumont, R.J.1
Richardson, I.B.2
Gaff, C.3
Gerondakis, S.4
-
19
-
-
0026592340
-
A novel complex between the p65 subunit of NF-kappa B and c-Rel binds to a DNA element involved in the phorbol ester induction of the human urokinase gene
-
Hansen, S.K., Nerlov, C., Zabel, U., Verde, P., Johnsen, M., Baeuerle, P.A., Blasi, F., A novel complex between the p65 subunit of NF-kappa B and c-Rel binds to a DNA element involved in the phorbol ester induction of the human urokinase gene. EMBO J. 11 (1992), 205–213.
-
(1992)
EMBO J.
, vol.11
, pp. 205-213
-
-
Hansen, S.K.1
Nerlov, C.2
Zabel, U.3
Verde, P.4
Johnsen, M.5
Baeuerle, P.A.6
Blasi, F.7
-
20
-
-
78650859531
-
NF-κB and STAT3 - key players in liver inflammation and cancer
-
He, G., Karin, M., NF-κB and STAT3 - key players in liver inflammation and cancer. Cell Res. 21 (2011), 159–168.
-
(2011)
Cell Res.
, vol.21
, pp. 159-168
-
-
He, G.1
Karin, M.2
-
21
-
-
57449112781
-
Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats
-
Herold, M.J., van den Brandt, J., Seibler, J., Reichardt, H.M., Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats. Proc. Natl. Acad. Sci. USA 105 (2008), 18507–18512.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18507-18512
-
-
Herold, M.J.1
van den Brandt, J.2
Seibler, J.3
Reichardt, H.M.4
-
22
-
-
84920188244
-
Nuclear factor-kappa B1 is associated with gastric cancer in a Chinese population
-
Hua, T., Qinsheng, W., Xuxia, W., Shuguang, Z., Ming, Q., Zhenxiong, L., Jingjie, W., Nuclear factor-kappa B1 is associated with gastric cancer in a Chinese population. Medicine., 93, 2014, e279.
-
(2014)
Medicine.
, vol.93
, pp. e279
-
-
Hua, T.1
Qinsheng, W.2
Xuxia, W.3
Shuguang, Z.4
Ming, Q.5
Zhenxiong, L.6
Jingjie, W.7
-
23
-
-
23844445451
-
Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling
-
Jenkins, B.J., Grail, D., Nheu, T., Najdovska, M., Wang, B., Waring, P., Inglese, M., McLoughlin, R.M., Jones, S.A., Topley, N., et al. Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling. Nat. Med. 11 (2005), 845–852.
-
(2005)
Nat. Med.
, vol.11
, pp. 845-852
-
-
Jenkins, B.J.1
Grail, D.2
Nheu, T.3
Najdovska, M.4
Wang, B.5
Waring, P.6
Inglese, M.7
McLoughlin, R.M.8
Jones, S.A.9
Topley, N.10
-
24
-
-
0029901047
-
Dietary salt, nitrate and stomach cancer mortality in 24 countries
-
Joossens, J.V., Hill, M.J., Elliott, P., Stamler, R., Lesaffre, E., Dyer, A., Nichols, R., Kesteloot, H., European Cancer Prevention (ECP) and the INTERSALT Cooperative Research Group. Dietary salt, nitrate and stomach cancer mortality in 24 countries. Int. J. Epidemiol. 25 (1996), 494–504.
-
(1996)
Int. J. Epidemiol.
, vol.25
, pp. 494-504
-
-
Joossens, J.V.1
Hill, M.J.2
Elliott, P.3
Stamler, R.4
Lesaffre, E.5
Dyer, A.6
Nichols, R.7
Kesteloot, H.8
-
25
-
-
84903485542
-
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice
-
Jurk, D., Wilson, C., Passos, J.F., Oakley, F., Correia-Melo, C., Greaves, L., Saretzki, G., Fox, C., Lawless, C., Anderson, R., et al. Chronic inflammation induces telomere dysfunction and accelerates ageing in mice. Nat. Commun., 2, 2014, 4172.
-
(2014)
Nat. Commun.
, vol.2
, pp. 4172
-
-
Jurk, D.1
Wilson, C.2
Passos, J.F.3
Oakley, F.4
Correia-Melo, C.5
Greaves, L.6
Saretzki, G.7
Fox, C.8
Lawless, C.9
Anderson, R.10
-
26
-
-
0347917295
-
Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis
-
Karban, A.S., Okazaki, T., Panhuysen, C.I., Gallegos, T., Potter, J.J., Bailey-Wilson, J.E., Silverberg, M.S., Duerr, R.H., Cho, J.H., Gregersen, P.K., et al. Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis. Hum. Mol. Genet. 13 (2004), 35–45.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 35-45
-
-
Karban, A.S.1
Okazaki, T.2
Panhuysen, C.I.3
Gallegos, T.4
Potter, J.J.5
Bailey-Wilson, J.E.6
Silverberg, M.S.7
Duerr, R.H.8
Cho, J.H.9
Gregersen, P.K.10
-
27
-
-
77953859606
-
NF-kappaB as a critical link between inflammation and cancer
-
Karin, M., NF-kappaB as a critical link between inflammation and cancer. Cold Spring Harb. Perspect. Biol., 1, 2009, a000141.
-
(2009)
Cold Spring Harb. Perspect. Biol.
, vol.1
, pp. a000141
-
-
Karin, M.1
-
28
-
-
84868628410
-
Tpl2 regulates intestinal myofibroblast HGF release to suppress colitis-associated tumorigenesis
-
Koliaraki, V., Roulis, M., Kollias, G., Tpl2 regulates intestinal myofibroblast HGF release to suppress colitis-associated tumorigenesis. J. Clin. Invest. 122 (2012), 4231–4242.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 4231-4242
-
-
Koliaraki, V.1
Roulis, M.2
Kollias, G.3
-
29
-
-
84896735766
-
Voom: precision weights unlock linear model analysis tools for RNA-seq read counts
-
Law, C.W., Chen, Y., Shi, W., Smyth, G.K., Voom: precision weights unlock linear model analysis tools for RNA-seq read counts. Genome Biol., 15(2), 2014, R29.
-
(2014)
Genome Biol.
, vol.15
, Issue.2
, pp. R29
-
-
Law, C.W.1
Chen, Y.2
Shi, W.3
Smyth, G.K.4
-
30
-
-
35148860766
-
Polymorphism in the promoter region of the NFKB1 gene increases the risk of sporadic colorectal cancer in Swedish but not in Chinese populations
-
Lewander, A., Butchi, A.K., Gao, J., He, L.J., Lindblom, A., Arbman, G., Carstensen, J., Zhang, Z.Y., Sun, X.F., Swedish Low-Risk Colorectal Cancer Study Group. Polymorphism in the promoter region of the NFKB1 gene increases the risk of sporadic colorectal cancer in Swedish but not in Chinese populations. Scand. J. Gastroenterol. 42 (2007), 1332–1338.
-
(2007)
Scand. J. Gastroenterol.
, vol.42
, pp. 1332-1338
-
-
Lewander, A.1
Butchi, A.K.2
Gao, J.3
He, L.J.4
Lindblom, A.5
Arbman, G.6
Carstensen, J.7
Zhang, Z.Y.8
Sun, X.F.9
-
31
-
-
85026329568
-
Association of NFKB1 and NFKBIA gene polymorphisms with susceptibility of gastric cancer
-
1010428317717107
-
Li, D., Wu, C., Cai, Y., Liu, B., Association of NFKB1 and NFKBIA gene polymorphisms with susceptibility of gastric cancer. Tumour Biol., 39(7), 2017 1010428317717107.
-
(2017)
Tumour Biol.
, vol.39
, Issue.7
-
-
Li, D.1
Wu, C.2
Cai, Y.3
Liu, B.4
-
32
-
-
84882670973
-
Functional Promoter −94 ins/del ATTG Polymorphism in NFKB1 Gene Is Associated with Bladder Cancer Risk in a Chinese Population
-
Li, P., Gu, J., Yang, X., Cai, H., Tao, J., Yang, X., et al. Functional Promoter −94 ins/del ATTG Polymorphism in NFKB1 Gene Is Associated with Bladder Cancer Risk in a Chinese Population. PLoS ONE, 8, 2013, e71604.
-
(2013)
PLoS ONE
, vol.8
, pp. e71604
-
-
Li, P.1
Gu, J.2
Yang, X.3
Cai, H.4
Tao, J.5
Yang, X.6
-
33
-
-
84897397058
-
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
-
Liao, Y., Smyth, G.K., Shi, W., featureCounts: an efficient general purpose program for assigning sequence reads to genomic features. Bioinformatics 30 (2014), 923–930.
-
(2014)
Bioinformatics
, vol.30
, pp. 923-930
-
-
Liao, Y.1
Smyth, G.K.2
Shi, W.3
-
34
-
-
84863577513
-
Association of an NFKB1 intron SNP (rs4648068) with gastric cancer patients in the Han Chinese population
-
Lu, R., Gao, X., Chen, Y., Ni, J., Yu, Y., Li, S., Guo, L., Association of an NFKB1 intron SNP (rs4648068) with gastric cancer patients in the Han Chinese population. BMC Gastroenterol., 12, 2012, 87.
-
(2012)
BMC Gastroenterol.
, vol.12
, pp. 87
-
-
Lu, R.1
Gao, X.2
Chen, Y.3
Ni, J.4
Yu, Y.5
Li, S.6
Guo, L.7
-
35
-
-
21244472975
-
IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
-
Maeda, S., Kamata, H., Luo, J.L., Leffert, H., Karin, M., IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 121 (2005), 977–990.
-
(2005)
Cell
, vol.121
, pp. 977-990
-
-
Maeda, S.1
Kamata, H.2
Luo, J.L.3
Leffert, H.4
Karin, M.5
-
36
-
-
84949681428
-
The good and the bad faces of STAT1 in solid tumours
-
Meissl, K., Macho-Maschler, S., Müller, M., Strobl, B., The good and the bad faces of STAT1 in solid tumours. Cytokine 89 (2017), 12–20.
-
(2017)
Cytokine
, vol.89
, pp. 12-20
-
-
Meissl, K.1
Macho-Maschler, S.2
Müller, M.3
Strobl, B.4
-
37
-
-
43749098070
-
NF-kappaB and cancer-identifying targets and mechanisms
-
Naugler, W.E., Karin, M., NF-kappaB and cancer-identifying targets and mechanisms. Curr. Opin. Genet. Dev. 18 (2008), 19–26.
-
(2008)
Curr. Opin. Genet. Dev.
, vol.18
, pp. 19-26
-
-
Naugler, W.E.1
Karin, M.2
-
38
-
-
77953496625
-
The NF-kappaB family of transcription factors and its regulation
-
Oeckinghaus, A., Ghosh, S., The NF-kappaB family of transcription factors and its regulation. Cold Spring Harb. Perspect. Biol., 1, 2009, a000034.
-
(2009)
Cold Spring Harb. Perspect. Biol.
, vol.1
, pp. a000034
-
-
Oeckinghaus, A.1
Ghosh, S.2
-
39
-
-
84893965118
-
Immune modulation in cancer with antibodies
-
Page, D.B., Postow, M.A., Callahan, M.K., Allison, J.P., Wolchok, J.D., Immune modulation in cancer with antibodies. Annu. Rev. Med. 65 (2014), 185–202.
-
(2014)
Annu. Rev. Med.
, vol.65
, pp. 185-202
-
-
Page, D.B.1
Postow, M.A.2
Callahan, M.K.3
Allison, J.P.4
Wolchok, J.D.5
-
40
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll, D.M., The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer 12 (2012), 252–264.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
41
-
-
70350513270
-
Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases
-
Pasparakis, M., Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases. Nat. Rev. Immunol. 9 (2009), 778–788.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 778-788
-
-
Pasparakis, M.1
-
42
-
-
84979917177
-
Robust Hyperparameter Estimation Protects against Hypervariable Genes and Improves Power to Detect Differential Expression
-
Phipson, B., Lee, S., Majewski, I.J., Alexander, W.S., Smyth, G.K., Robust Hyperparameter Estimation Protects against Hypervariable Genes and Improves Power to Detect Differential Expression. Ann. Appl. Stat. 10 (2016), 946–963.
-
(2016)
Ann. Appl. Stat.
, vol.10
, pp. 946-963
-
-
Phipson, B.1
Lee, S.2
Majewski, I.J.3
Alexander, W.S.4
Smyth, G.K.5
-
43
-
-
84881534116
-
Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically
-
Putoczki, T.L., Thiem, S., Loving, A., Busuttil, R.A., Wilson, N.J., Ziegler, P.K., Nguyen, P.M., Preaudet, A., Farid, R., Edwards, K.M., et al. Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically. Cancer Cell 24 (2013), 257–271.
-
(2013)
Cancer Cell
, vol.24
, pp. 257-271
-
-
Putoczki, T.L.1
Thiem, S.2
Loving, A.3
Busuttil, R.A.4
Wilson, N.J.5
Ziegler, P.K.6
Nguyen, P.M.7
Preaudet, A.8
Farid, R.9
Edwards, K.M.10
-
44
-
-
84923094572
-
Upregulation of PD-L1 and APE1 is associated with tumorigenesis and poor prognosis of gastric cancer
-
Qing, Y., Li, Q., Ren, T., Xia, W., Peng, Y., Liu, G.L., Luo, H., Yang, Y.X., Dai, X.Y., Zhou, S.F., Wang, D., Upregulation of PD-L1 and APE1 is associated with tumorigenesis and poor prognosis of gastric cancer. Drug Des. Devel. Ther. 9 (2015), 901–909.
-
(2015)
Drug Des. Devel. Ther.
, vol.9
, pp. 901-909
-
-
Qing, Y.1
Li, Q.2
Ren, T.3
Xia, W.4
Peng, Y.5
Liu, G.L.6
Luo, H.7
Yang, Y.X.8
Dai, X.Y.9
Zhou, S.F.10
Wang, D.11
-
45
-
-
33748865331
-
Empirical array quality weights in the analysis of microarray data
-
Ritchie, M.E., Diyagama, D., Neilson, J., van Laar, R., Dobrovic, A., Holloway, A., Smyth, G.K., Empirical array quality weights in the analysis of microarray data. BMC Bioinformatics, 7, 2006, 261.
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 261
-
-
Ritchie, M.E.1
Diyagama, D.2
Neilson, J.3
van Laar, R.4
Dobrovic, A.5
Holloway, A.6
Smyth, G.K.7
-
46
-
-
84926507971
-
Limma powers differential expression analyses for RNA-sequencing and microarray studies
-
Ritchie, M.E., Phipson, B., Wu, D., Hu, Y., Law, C.W., Shi, W., Smyth, G.K., Limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res., 43, 2015, e47.
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. e47
-
-
Ritchie, M.E.1
Phipson, B.2
Wu, D.3
Hu, Y.4
Law, C.W.5
Shi, W.6
Smyth, G.K.7
-
47
-
-
77953176036
-
A scaling normalization method for differential expression analysis of RNA-seq data
-
Robinson, M.D., Oshlack, A., A scaling normalization method for differential expression analysis of RNA-seq data. Genome Biol., 11, 2010, R25.
-
(2010)
Genome Biol.
, vol.11
, pp. R25
-
-
Robinson, M.D.1
Oshlack, A.2
-
48
-
-
75249087100
-
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
-
Robinson, M.D., McCarthy, D.J., Smyth, G.K., edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics. 26 (2010), 139–140.
-
(2010)
Bioinformatics.
, vol.26
, pp. 139-140
-
-
Robinson, M.D.1
McCarthy, D.J.2
Smyth, G.K.3
-
49
-
-
0035542950
-
Nuclear factor-kappaB p65 (RelA) transcription factor is constitutively activated in human gastric carcinoma tissue
-
Sasaki, N., Morisaki, T., Hashizume, K., Yao, T., Tsuneyoshi, M., Noshiro, H., Nakamura, K., Yamanaka, T., Uchiyama, A., Tanaka, M., Katano, M., Nuclear factor-kappaB p65 (RelA) transcription factor is constitutively activated in human gastric carcinoma tissue. Clin. Cancer Res. 7 (2001), 4136–4142.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 4136-4142
-
-
Sasaki, N.1
Morisaki, T.2
Hashizume, K.3
Yao, T.4
Tsuneyoshi, M.5
Noshiro, H.6
Nakamura, K.7
Yamanaka, T.8
Uchiyama, A.9
Tanaka, M.10
Katano, M.11
-
50
-
-
84875663378
-
A Comprehensive Profile of ChIP-Seq-Based STAT1 Target Genes Suggests the Complexity of STAT1-Mediated Gene Regulatory Mechanisms
-
Satoh, J., Tabunoki, H., A Comprehensive Profile of ChIP-Seq-Based STAT1 Target Genes Suggests the Complexity of STAT1-Mediated Gene Regulatory Mechanisms. Gene Regul. Syst. Bio. 7 (2013), 41–56.
-
(2013)
Gene Regul. Syst. Bio.
, vol.7
, pp. 41-56
-
-
Satoh, J.1
Tabunoki, H.2
-
51
-
-
84862520770
-
Fiji: an open-source platform for biological-image analysis
-
Schindelin, J., Arganda-Carreras, I., Frise, E., Kaynig, V., Longair, M., Pietzsch, T., Preibisch, S., Rueden, C., Saalfeld, S., Schmid, B., Tinevez, J.Y., White, D.J., Hartenstein, V., Eliceiri, K., Tomancak, P., Cardona, A., Fiji: an open-source platform for biological-image analysis. Nat Methods. 9 (2012), 676–682.
-
(2012)
Nat Methods.
, vol.9
, pp. 676-682
-
-
Schindelin, J.1
Arganda-Carreras, I.2
Frise, E.3
Kaynig, V.4
Longair, M.5
Pietzsch, T.6
Preibisch, S.7
Rueden, C.8
Saalfeld, S.9
Schmid, B.10
Tinevez, J.Y.11
White, D.J.12
Hartenstein, V.13
Eliceiri, K.14
Tomancak, P.15
Cardona, A.16
-
52
-
-
0022930702
-
Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism
-
Sen, R., Baltimore, D., Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism. Cell 47 (1986), 921–928.
-
(1986)
Cell
, vol.47
, pp. 921-928
-
-
Sen, R.1
Baltimore, D.2
-
53
-
-
0028804551
-
Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses
-
Sha, W.C., Liou, H.-C., Tuomanen, E.I., Baltimore, D., Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses. Cell 80 (1995), 321–330.
-
(1995)
Cell
, vol.80
, pp. 321-330
-
-
Sha, W.C.1
Liou, H.-C.2
Tuomanen, E.I.3
Baltimore, D.4
-
54
-
-
77449146686
-
Conditional deletion of IkappaB-kinase-beta accelerates helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia
-
e1021-1010
-
Shibata, W., Takaishi, S., Muthupalani, S., Pritchard, D.M., Whary, M.T., Rogers, A.B., Fox, J.G., Betz, K.S., Kaestner, K.H., Karin, M., Wang, T.C., Conditional deletion of IkappaB-kinase-beta accelerates helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia. Gastroenterology 138 (2010), 1022–1034 e1021-1010.
-
(2010)
Gastroenterology
, vol.138
, pp. 1022-1034
-
-
Shibata, W.1
Takaishi, S.2
Muthupalani, S.3
Pritchard, D.M.4
Whary, M.T.5
Rogers, A.B.6
Fox, J.G.7
Betz, K.S.8
Kaestner, K.H.9
Karin, M.10
Wang, T.C.11
-
55
-
-
84858720808
-
Dimer-specific regulatory mechanisms within the NF-κB family of transcription factors
-
Smale, S.T., Dimer-specific regulatory mechanisms within the NF-κB family of transcription factors. Immunol. Rev. 246 (2012), 193–204.
-
(2012)
Immunol. Rev.
, vol.246
, pp. 193-204
-
-
Smale, S.T.1
-
56
-
-
34249048365
-
Helicobacter pylori evolution and phenotypic diversification in a changing host
-
Suerbaum, S., Josenhans, C., Helicobacter pylori evolution and phenotypic diversification in a changing host. Nat. Rev. Microbiol. 5 (2007), 441–452.
-
(2007)
Nat. Rev. Microbiol.
, vol.5
, pp. 441-452
-
-
Suerbaum, S.1
Josenhans, C.2
-
57
-
-
77950183851
-
Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer
-
Sugimoto, M., Yamaoka, Y., Furuta, T., Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer. World J. Gastroenterol. 16 (2010), 1188–1200.
-
(2010)
World J. Gastroenterol.
, vol.16
, pp. 1188-1200
-
-
Sugimoto, M.1
Yamaoka, Y.2
Furuta, T.3
-
58
-
-
84925334953
-
Association of variants in genes encoding for macrophage-related functions with clinical outcome in patients with locoregional gastric cancer
-
Sunakawa, Y., Stremitzer, S., Cao, S., Zhang, W., Yang, D., Wakatsuki, T., Ning, Y., Yamauchi, S., Stintzing, S., Sebio, A., El-khoueiry, R., Matsusaka, S., Parekh, A., Barzi, A., Azuma, M., Watanabe, M., Koizumi, W., Lenz, H.-J., Association of variants in genes encoding for macrophage-related functions with clinical outcome in patients with locoregional gastric cancer. Ann. Oncol. 26 (2015), 332–339.
-
(2015)
Ann. Oncol.
, vol.26
, pp. 332-339
-
-
Sunakawa, Y.1
Stremitzer, S.2
Cao, S.3
Zhang, W.4
Yang, D.5
Wakatsuki, T.6
Ning, Y.7
Yamauchi, S.8
Stintzing, S.9
Sebio, A.10
El-khoueiry, R.11
Matsusaka, S.12
Parekh, A.13
Barzi, A.14
Azuma, M.15
Watanabe, M.16
Koizumi, W.17
Lenz, H.-J.18
-
59
-
-
0033943628
-
Dominant nonresponsiveness to Helicobacter pylori infection is associated with production of interleukin 10 but not gamma interferon
-
Sutton, P., Kolesnikow, T., Danon, S., Wilson, J., Lee, A., Dominant nonresponsiveness to Helicobacter pylori infection is associated with production of interleukin 10 but not gamma interferon. Infect. Immun. 68 (2000), 4802–4804.
-
(2000)
Infect. Immun.
, vol.68
, pp. 4802-4804
-
-
Sutton, P.1
Kolesnikow, T.2
Danon, S.3
Wilson, J.4
Lee, A.5
-
60
-
-
84923352598
-
Identification of STAT1 and STAT3 specific inhibitors using comparative virtual screening and docking validation
-
Szelag, M., Czerwoniec, A., Wesoly, J., Bluyssen, H.A., Identification of STAT1 and STAT3 specific inhibitors using comparative virtual screening and docking validation. PLoS ONE, 10, 2015, e0116688.
-
(2015)
PLoS ONE
, vol.10
, pp. e0116688
-
-
Szelag, M.1
Czerwoniec, A.2
Wesoly, J.3
Bluyssen, H.A.4
-
61
-
-
0030935260
-
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
-
Takeda, K., Noguchi, K., Shi, W., Tanaka, T., Matsumoto, M., Yoshida, N., Kishimoto, T., Akira, S., Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc. Natl. Acad. Sci. USA 94 (1997), 3801–3804.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3801-3804
-
-
Takeda, K.1
Noguchi, K.2
Shi, W.3
Tanaka, T.4
Matsumoto, M.5
Yoshida, N.6
Kishimoto, T.7
Akira, S.8
-
62
-
-
0036796060
-
Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice
-
Tebbutt, N.C., Giraud, A.S., Inglese, M., Jenkins, B., Waring, P., Clay, F.J., Malki, S., Alderman, B.M., Grail, D., Hollande, F., Heath, J.K., Ernst, M., Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice. Nature Medicine 8 (2002), 1089–1097.
-
(2002)
Nature Medicine
, vol.8
, pp. 1089-1097
-
-
Tebbutt, N.C.1
Giraud, A.S.2
Inglese, M.3
Jenkins, B.4
Waring, P.5
Clay, F.J.6
Malki, S.7
Alderman, B.M.8
Grail, D.9
Hollande, F.10
Heath, J.K.11
Ernst, M.12
-
63
-
-
84924271853
-
Global cancer statistics, 2012
-
Torre, L.A., Bray, F., Siegel, R.L., Ferlay, J., Lortet-Tieulent, J., Jemal, A., Global cancer statistics, 2012. CA Cancer J. Clin. 65 (2015), 87–108.
-
(2015)
CA Cancer J. Clin.
, vol.65
, pp. 87-108
-
-
Torre, L.A.1
Bray, F.2
Siegel, R.L.3
Ferlay, J.4
Lortet-Tieulent, J.5
Jemal, A.6
-
64
-
-
85016307327
-
Mechanisms and consequences of Jak-STAT signaling in the immune system
-
Villarino, A.V., Kanno, Y., O'Shea, J.J., Mechanisms and consequences of Jak-STAT signaling in the immune system. Nat. Immunol. 18 (2017), 374–384.
-
(2017)
Nat. Immunol.
, vol.18
, pp. 374-384
-
-
Villarino, A.V.1
Kanno, Y.2
O'Shea, J.J.3
-
65
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
Wang, H., Yang, H., Shivalila, C.S., Dawlaty, M.M., Cheng, A.W., Zhang, F., Jaenisch, R., One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153 (2013), 910–918.
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
Zhang, F.6
Jaenisch, R.7
-
66
-
-
0030988261
-
Regulation of NFKB1 proteins by the candidate oncoprotein BCL-3: generation of NF-kappaB homodimers from the cytoplasmic pool of p50-p105 and nuclear translocation
-
Watanabe, N., Iwamura, T., Shinoda, T., Fujita, T., Regulation of NFKB1 proteins by the candidate oncoprotein BCL-3: generation of NF-kappaB homodimers from the cytoplasmic pool of p50-p105 and nuclear translocation. EMBO J. 16 (1997), 3609–3620.
-
(1997)
EMBO J.
, vol.16
, pp. 3609-3620
-
-
Watanabe, N.1
Iwamura, T.2
Shinoda, T.3
Fujita, T.4
-
67
-
-
84928034618
-
NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma
-
Wilson, C.L., Jurk, D., Fullard, N., Banks, P., Page, A., Luli, S., Elsharkawy, A.M., Gieling, R.G., Chakraborty, J.B., Fox, C., et al. NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma. Nat. Commun., 6, 2015, 6818.
-
(2015)
Nat. Commun.
, vol.6
, pp. 6818
-
-
Wilson, C.L.1
Jurk, D.2
Fullard, N.3
Banks, P.4
Page, A.5
Luli, S.6
Elsharkawy, A.M.7
Gieling, R.G.8
Chakraborty, J.B.9
Fox, C.10
-
68
-
-
78049354889
-
Helicobacter pylori and gastric cancer: factors that modulate disease risk
-
Wroblewski, L.E., Peek, R.M. Jr., Wilson, K.T., Helicobacter pylori and gastric cancer: factors that modulate disease risk. Clin. Microbiol. Rev. 23 (2010), 713–739.
-
(2010)
Clin. Microbiol. Rev.
, vol.23
, pp. 713-739
-
-
Wroblewski, L.E.1
Peek, R.M.2
Wilson, K.T.3
-
69
-
-
34249775191
-
Elevated plasma osteopontin associated with gastric cancer development, invasion and survival
-
Wu, C.Y., Wu, M.S., Chiang, E.P., Wu, C.C., Chen, Y.J., Chen, C.J., Chi, N.H., Chen, G.H., Lin, J.T., Elevated plasma osteopontin associated with gastric cancer development, invasion and survival. Gut 56 (2007), 782–789.
-
(2007)
Gut
, vol.56
, pp. 782-789
-
-
Wu, C.Y.1
Wu, M.S.2
Chiang, E.P.3
Wu, C.C.4
Chen, Y.J.5
Chen, C.J.6
Chi, N.H.7
Chen, G.H.8
Lin, J.T.9
-
70
-
-
77955889132
-
ROAST: rotation gene set tests for complex microarray experiments
-
Wu, D., Lim, E., Vaillant, F., Asselin-Labat, M.L., Visvader, J.E., Smyth, G.K., ROAST: rotation gene set tests for complex microarray experiments. Bioinformatics 26 (2010), 2176–2182.
-
(2010)
Bioinformatics
, vol.26
, pp. 2176-2182
-
-
Wu, D.1
Lim, E.2
Vaillant, F.3
Asselin-Labat, M.L.4
Visvader, J.E.5
Smyth, G.K.6
-
71
-
-
79951818786
-
NF-κB1 inhibits TLR-induced IFN-β production in macrophages through TPL-2-dependent ERK activation
-
Yang, H.T., Wang, Y., Zhao, X., Demissie, E., Papoutsopoulou, S., Mambole, A., O'Garra, A., Tomczak, M.F., Erdman, S.E., Fox, J.G., et al. NF-κB1 inhibits TLR-induced IFN-β production in macrophages through TPL-2-dependent ERK activation. J. Immunol. 186 (2011), 1989–1996.
-
(2011)
J. Immunol.
, vol.186
, pp. 1989-1996
-
-
Yang, H.T.1
Wang, Y.2
Zhao, X.3
Demissie, E.4
Papoutsopoulou, S.5
Mambole, A.6
O'Garra, A.7
Tomczak, M.F.8
Erdman, S.E.9
Fox, J.G.10
-
72
-
-
79955757521
-
NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ
-
Zhi, H., Yang, L., Kuo, Y.L., Ho, Y.K., Shih, H.M., Giam, C.Z., NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ. PLoS Pathog., 7, 2011, e1002025.
-
(2011)
PLoS Pathog.
, vol.7
, pp. e1002025
-
-
Zhi, H.1
Yang, L.2
Kuo, Y.L.3
Ho, Y.K.4
Shih, H.M.5
Giam, C.Z.6
|