Nanocapsules formation by nano spray drying

Nanoencapsulation Technologies for the Food and Nutraceutical Industries

Volumn , Issue , 2017, Pages 346-401

  Arpagaus, Cordin ^a   John, Philipp ^b   Collenberg, Andreas ^b   Rütti, David ^b  

^a Landscape Architecture   (Switzerland)

^b BüCHI Labortechnik AG   (Switzerland)

Author keywords

Electrostatic precipitator; Encapsulation; Nano spray drying; Nanocapsule; Nanoparticle; Particle morphology; Particle size; Process optimization; Spray drying; Vibrating mesh technology

Indexed keywords

CONTROLLED DRUG DELIVERY; DRYERS (EQUIPMENT); ELECTROSTATIC PRECIPITATORS; ENCAPSULATION; LABORATORIES; MORPHOLOGY; NANOCAPSULES; NANOPARTICLES; OPTIMIZATION; PARTICLE SIZE; PRECIPITATION (CHEMICAL);

CONTROLLABLE MORPHOLOGY; ENCAPSULATION EFFICIENCY; LABORATORY EQUIPMENTS; MARKET INTRODUCTION; PARTICLE MORPHOLOGIES; SPRAY DRYING PROCESS; SPRAY DRYING TECHNIQUE; SUB-MICRON PARTICLES;

SPRAY DRYING;

EID: 85043500668     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-809436-5.00010-0     Document Type: Chapter

References (136)

1. Ahmad M.I., Ungphaiboon S., Srichana T. The development of dimple-shaped chitosan carrier for ethambutol dihydrochloride dry powder inhaler. Drug Dev. Ind. Pharm. 2014, 41:791-800.
2. Anandharamakrishnan C. Drying techniques for nanoencapsulation. Techniques for Nanoencapsulation of Food Ingredients 2014, 51-60. Springer, New York.
3. Anandharamakrishnan C., Padma Ishwarya S. Spray drying for nanoencapsulation of food components. Spray Drying Techniques for Food Ingredient Encapsulation 2015, 180-197. John Wiley & Sons, Ltd., Chichester, UK, (Chapter 8).
4. Aquino R.P., Stigliani M., Del Gaudio P., Mencherini T., Sansone F., Russo P. Nanospray drying as a novel technique for the manufacturing of inhalable NSAID powders. Hindawi Publ. Corp. Sci. World J. 2014, 1-7.
5. Arpagaus, C., 2010. Spray Drying R and D Solutions-BüCHI's Nano Spray Dryer: A world novelty in laboratory scale. ONdrugDelivery, pp. 30-31. Available from: . http://www.ondrugdelivery.com/.
6. Arpagaus, C., 2011. Nano Spray Dryer B-90: Literature review and applications, bestatbuchi Information Bulletin, Number 63/2011.
7. Arpagaus C. A novel laboratory-scale spray dryer to produce nanoparticles. Dry. Technol. 2012, 30:1113-1121.
8. Arpagaus C., Meuri M. Laboratory scale spray drying of inhalable particles: a review. Respir. Drug Deliv. 2010, 2:469-476.
9. Arpagaus, C., Schafroth, N., 2007. Spray Dried Biodegradable Polymers as target material for Controlled Drug Delivery, bestatbuchi Information Bulletin, Number 46/2007.
10. Arpagaus, C., Schwartzbach, H., 2008. Scale-up from the Büchi Mini Spray Dryer B-290 to the Niro MOBILE MINOR, bestatbuchi Information Bulletin, Number 52/2008.
11. Arpagaus C., Schafroth N. Laboratory scale spray drying of biodegradable polymers. Respir. Drug Deliv. Eur. 2009, 2:269-274.
12. Arpagaus, C., Schafroth, N., Meuri, M., 2010a. Laboratory scale spray drying of lactose: a review, bestatbuchi Information Bulletin, Number 57/2010.
13. Arpagaus, C., Schafroth, N., Meuri, M., 2010b. Laboratory scale spray drying of inhalable drugs: a review, bestatbuchi Information Bulletin, Number 59/2010.
14. Arpagaus C., Rütti D., Meuri M. Enhanced solubility of poorly soluble drugs via spray drying. Drug Delivery Strategies for Poorly Water-Soluble Drugs 2013, 551-585. John Wiley & Sons, Ltd. D. Douroumis, A. Fahr (Eds.).
15. Assadpour E., Jafari S.M., Maghsoudlou Y. Evaluation of folic acid release from spray dried powder particles of pectin-whey protein nano-capsules. International J. Biol. Macromol. 2017, 95:238-247.
16. Assadpour E., Jafari S.M. Spray drying of folic acid within nano-emulsions; optimization by taguchi approach. Drying Technol. 2017, doi:10.1080/07373937.2016.1242016.
17. Baba K., Nishida K. Calpain inhibitor nanocrystals prepared using Nano Spray Dryer B-90. Nanoscale Res. Lett. 2012, 7:1-9.
18. Baba K., Nishida K. Steroid nanocrystals prepared using the nano spray dryer B-90. Pharmaceutics 2013, 5:107-114.
19. Beber T.C., Andrade D.F., Kann B., Fontana M.C., Coradini K., Windbergs M., Beck R.C.R. Submicron polymeric particles prepared by vibrational spray-drying: semisolid formulation and skin penetration/permeation studies. Eur. J. Pharm. Biopharm. 2014, 88:602-613.
20. Beck-Broichsitter M., Schweiger C., Schmehl T., Gessler T., Seeger W., Kissel T. Characterization of novel spray-dried polymeric particles for controlled pulmonary drug delivery. J. Control. Release 2012, 158:329-335.
21. Beck-Broichsitter M., Paulus I.E., Greiner A., Kissel T. Modified vibrating-mesh nozzles for advanced spray-drying applications. Eur. J. Pharm. Biopharm. 2015, 92:96-101.
22. Beck-Broichsitter M., Strehlow B., Kissel T. Direct fractionation of spray-dried polymeric microparticles by inertial impaction. Powder Technol. 2015, 286:311-317.
23. Bege N., Renette T., Endres T., Beck-Broichsitter M., Hänggi D., Kissel T. In situ forming nimodipine depot system based on microparticles for the treatment of posthemorrhagic cerebral vasospasm. Eur. J. Pharm. Biopharm. 2013, 84:99-105.
24. Behara S.R.B., Farkas D.R., Hindle M., Longest P.W. Development of a high efficiency dry powder inhaler: effects of capsule chamber design and inhaler surface modifications. Pharm. Res. 2014, 31:360-372.
25. Behara S.R.B., Longest P.W., Farkas D.R., Hindle M. Development and comparison of new high-efficiency dry powder inhalers for carrier-free formulations. J. Pharm. Sci. 2014, 103:465-477.
26. Blasi, P., Schoubben, A., Giovagnoli, S., Rossi, C., Ricci, M., 2010. Alginate micro- and nanoparticle production by spray drying. Proc. Meet. Lact. as a Carr. Inhal. Prod. Parma, Italy, Sept. 26-28, 2010, pp. 137-138.
27. Bowen M., Turok R., Maa Y.-F. Spray drying of monoclonal antibodies: investigating powder-based biologic drug substance bulk storage. Dry. Technol. 2013, 31:1441-1450.
28. Brandenberger, H., 2003. Development of a novel high-performacne cyclone to increase the yield in a Mini Spray Dryer, bestatbuchi Information Bulletin, Number 27/2003.
29. Brinkmann-Trettenes U., Barnert S., Bauer-Brandl A. Single step bottom-up process to generate solid phospholipid nano-particles. Pharm. Dev. Technol. 2014, 19:326-332.
30. Büchi Labortechnik, AG, 2010. Nano Spray Dryer B-90 Brochure, Flawil, Switzerland, 11592236 en 1012. Available from: . http://www.buchi.com/.
31. Büchi Labortechnik, AG, 2013. Nano Spray Dryer B-90 Technical data sheet, en 1311 A. Available from: . http://static2.buchi.com/sites/default/files/technical-data-pdf/B-90_Data_Sheet_en_A_0.pdf.
32. Büchi Labortechnik, AG, 2015. Spray Drying & Encapsulation Solutions-Particle formation for lab scale. Brochure, No. 11592837 en 15/09 E 24 pp.
33. Bürki K., Jeon I., Arpagaus C., Betz G. New insights into respirable protein powder preparation using a nano spray dryer. Int. J. Pharm. 2011, 408:248-256.
34. Celli G.B., Ghanem A., Brooks M.S.-L. Bioactive encapsulated powders for functional foods-a review of methods and current limitations. Food Bioproc. Technol. 2015, 8:1825-1837.
35. Cerchiara T., Abruzzo A., di Cagno M., Bigucci F., Bauer-Brandl A., Parolin C., Vitali B., Gallucci M.C., Luppi B. Chitosan based micro- and nanoparticles for colon-targeted delivery of vancomycin prepared by alternative processing methods. Eur. J. Pharm. Biopharm. 2015, 92:112-119.
36. Chan H.-K., Kwok P.C.L. Production methods for nanodrug particles using the bottom-up approach. Adv. Drug Deliv. Rev. 2011, 63:406-416.
37. Couvreur P., Dubernet C., Puisieux F. Controlled drug delivery with nanoparticles-current possibilities and future trends. Eur. J. Pharm. Biopharm. 1995, 41:2-13.
38. Dahili L.A., Feczkó T. Cross-linking of horseradish peroxidase enzyme to fine particles generated by Nano Spray Dryer B-90. Period. Polytech. Chem. Eng. 2015, 59:209-214.
39. Dahili L.A., Kelemen-Horváth I., Feczkó T. 2,4-Dichlorophenol removal by purified horseradish peroxidase enzyme and crude extract from horseradish immobilized to nano spray dried ethyl cellulose particles. Process Biochem. 2015, 50:1835-1842.
40. De Cicco F., Porta A., Sansone F., Aquino R.P., Del Gaudio P. Nanospray technology for an in situ gelling nanoparticulate powder as a wound dressing. Int. J. Pharm. 2014, 473:30-37.
41. Dhand R. Nebulizer that use a vibrating mesh or plate with multiple apertures to generate aerosol. Respir. Care 2002, 47(12):1406-1418.
42. Dhillon G.S., Kaur S., Brar S.K. Facile fabrication and characterization of chitosan-based zinc oxide nanoparticles and evaluation of their antimicrobial and antibiofilm activity. Int. Nano Lett. 2014, 4:107.
43. Dimer F., de Souza Carvalho-Wodarz C., Haupenthal J., Hartmann R., Lehr C.-M. Inhalable clarithromycin microparticles for treatment of respiratory infections. Pharm. Res. 2015, 32:3850-3861.
44. Dimer F., Ortiz M., Pohlmann A.R., Guterres S.S. Inhalable resveratrol microparticles produced by vibrational atomization spray drying for treating pulmonary arterial hypertension. J. Drug Deliv. Sci. Technol. 2015, 29:152-158.
45. Draheim C., de Crécy F., Hansen S., Collnot E.-M., Lehr C.-M. A design of experiment study of nanoprecipitation and nano spray drying as processes to prepare plga nano- and microparticles with defined sizes and size distributions. Pharm. Res. 2015, 32:2609-2624.
46. Durli T.L., Dimer F.A., Fontana M.C., Pohlmann A.R., Beck R.C.R., Guterres S.S. Innovative approach to produce submicron drug particles by vibrational atomization spray drying: influence of the type of solvent and surfactant. Drug Dev. Ind. Pharm. 2014, 40:1011-1020.
47. Esfanjani A.F., Jafari S.M., Assadpoor E., Mohammadi A. Nano-encapsulation of saffron extract through double-layered multiple emulsions of pectin and whey protein concentrate. J. Food Eng. 2015, 165:149-155.
48. Estevinho B.N., Rocha F., Santos L., Alves A. Microencapsulation with chitosan by spray drying for industry applications-a review. Trends Food Sci. Technol. 2013, 31:138-155.
49. Ezhilarasi P.N., Karthik P., Chhanwal N., Anandharamakrishnan C. Nanoencapsulation techniques for food bioactive components: a review. Food Bioproc. Technol. 2013, 6:628-647.
50. Fang Z., Bhandari B. Encapsulation techniques for food ingredient systems. Food Materials Science and Engineering 2012, 320-348. Blackwell Publishing Ltd., Oxford, UK, (Chapter 12). B. Bhandari, Y.H. Roos (Eds.).
51. Farkas D.R., Hindle M., Longest P.W. Characterization of a new high-dose dry powder inhaler (DPI) based on a fluidized bed design. Ann. Biomed. Eng. 2015, 43:2804-2815.
52. Faridi Esfanjani A.F., Jafari S.M. Biopolymer nano-particles and natural nano-carriers for nano-encapsulation of phenolic compounds. Colloids Surf. B. 2016, 146:532-543.
53. Fathi M., Martin A., McClements D.J. Nanoencapsulation of food ingredients using carbohydrate based delivery systems. Trends Food Sci. Technol. 2014, 39:18-39.
54. Faulhammer E., Wahl V., Zellnitz S., Khinast J.G., Paudel A. Carrier-based dry powder inhalation: Impact of carrier modification on capsule filling processability and in vitro aerodynamic performance. Int. J. Pharm. 2015, 491:231-242.
55. Feng A.L., Boraey M.A., Gwin M.A., Finlay P.R., Kuehl P.J., Vehring R. Mechanistic models facilitate efficient development of leucine containing microparticles for pulmonary drug delivery. Int. J. Pharm. 2011, 409:156-163.
56. Fontana M.C., Durli T.L., Pohlmann A.R., Guterres S.S., Beck R.C.R. Polymeric controlled release inhalable powder produced by vibrational spray-drying: one-step preparation and in vitro lung deposition. Powder Technol. 2014, 258:49-59.
57. Gautier S., Arpagaus C., Schafroth N., Meuri M., Deschamps A., Maquet V. Very fine chitosan microparticles with narrow & controlled size distribution using spray-drying technologies. Drug Deliv. Technol. 2010, 10:30-37.
58. Gharsallaoui A., Roudaut G., Chambin O., Voilley A., Saurel R. Applications of spray-drying in microencapsulation of food ingredients: an overview. Food Res. Int. 2007, 40:1107-1121.
59. Ghazanfari T., Elhissi A.M.A., Ding Z., Taylor K.M.G. The influence of fluid physicochemical properties on vibrating-mesh nebulization. Int. J. Pharm. 2007, 339:103-111.
60. Gu B., Linehan B., Tseng Y.-C. Optimization of the Büchi B-90 spray drying process using central composite design for preparation of solid dispersions. Int. J. Pharm. 2015, 491:208-217.
61. Haggag Y.A., Faheem A.M. Evaluation of nano spray drying as a method for drying and formulation of therapeutic peptides and proteins. Front. Pharmacol. 2015, 6:1-5.
62. Harsha S. Pharmaceutical suspension containing both immediate/sustained-release amoxicillin-loaded gelatin nanoparticles: Preparation and in vitro characterization. Drug Des. Devel. Ther. 2013, 7:1027-1033.
63. Harsha S. In vitro and in vivo evaluation of nanoparticles prepared by nano spray drying for stomach mucoadhesive drug delivery. Dry. Technol. 2015, 33:1199-1209.
64. Harsha S., Aldhubiab B.E., Alhaider I.A., Attimarad M., Nair A. Carbopol 934-P loaded with vildagliptin for diabetic delivery: in vitro and in vivo evaluation of nanoparticles. Curr. Nanosci. 2013, 9:642-647.
65. Harsha S., Attimard M., Khan T.A., Nair A.B., Aldhubiab B.E., Sangi S., Shariff A. Design and formulation of mucoadhesive microspheres of sitagliptin. J. Microencapsul. 2013, 30:257-264.
66. Harsha S., Aldhubiab B.E., Nair A.B., Alhaider I.A., Attimarad M., Venugopala K.N., Srinivasan S., Gangadhar N., Asif A.H. Nanoparticle formulation by Büchi B-90 Nano Spray Dryer for oral mucoadhesion. Drug Des. Devel. Ther. 2015, 9:273-282.
67. Harsha S., Al-Dhubiab B.E., Nair A.B., Al-Khars M., Al-Hassan M., Rajan R., Attimarad M., Venugopala K.N., Asif A.H. Novel drying technology of microsphere and its evaluation for targeted drug delivery for lungs. Dry. Technol. 2015, 33:502-512.
68. Heng D., Lee S.H., Ng W.K., Tan R.B.H. The Nano Spray Dryer B-90. Expert Opin. Drug Deliv. 2011, 8:965-972.
69. Hindle M., Kaviratna A., Yamarthi D., Longest P.W. Characterization of spray dried azithromycin dry powders for inhalation. J. Aerosol Med. Pulmonary Drug Deliv. 2015, 4:A9.
70. Jafari S.M., He Y., Bhandari B. Encapsulation of Nanoparticles of d-limonene by spray drying: role of emulsifiers and emulsifying techniques. Dry. Technol. 2007, 25:1069-1079.
71. Jafari S.M., He Y., Bhandari B. Role of powder particle size on the encapsulation efficiency of oils during spray drying. Dry. Technol. 2007, 26:1081-1089.
72. Jafari S.M., Assadpoor E., Bhandari B., He Y. Nano-particle encapsulation of fish oil by spray drying. Food Res. Int. 2008, 41:172-183.
73. Jafari S.M., Assadpoor E., He Y., Bhandari B. Encapsulation efficiency of food flavours and oils during spray drying. Dry. Technol. 2008, 26:816-835.
74. Jain, I., 2014. Crosslinking albumin for drug release from spray dried particles, Master Thesis, Electronic Thesis and Dissertations, Paper 674. University of Louisville, USA.
75. Kanogwan K., Srichana T. Nano spray-dried pyrazinamide-l-leucine dry powders, physical properties and feasibility used as dry powder aerosols. Pharm. Dev. Technol. 2016, 21(1):68-75.
76. Katouzian I., Jafari S.M. Nano-encapsulation as a promising approach for targeted delivery and controlled release of vitamins. Trends Food Sci. Technol. 2016, 53:34-48.
77. Knoch M., Keller M. The customised electronic nebuliser: a new category of liquid aerosol drug delivery systems. Expert Opin. Drug Deliv. 2005, 2:377-390.
78. Lass J.S., Sant A., Knoch M. New advances in aerosolised drug delivery: vibrating membrane nebuliser technology. Expert Opin. Drug Deliv. 2006, 3:693-702.
79. Lee S.H., Heng D., Ng W.K., Chan H.-K., Tan R.B.H. Nano spray drying: a novel method for preparing protein nanoparticles for protein therapy. Int. J. Pharm. 2011, 403:192-200.
80. Lee S.H., Teo J., Heng D., Ng W.K., Chan H.K., Tan R.B.H. Synergistic combination dry powders for inhaled antimicrobial therapy: formulation, characterization and in vitro evaluation. Eur. J. Pharm. Biopharm. 2013, 83:275-284.
81. Li X., Anton N., Arpagaus C., Belleteix F., Vandamme T.F. Nanoparticles by spray drying using innovative new technology: the Büchi Nano Spray Dryer B-90. J. Control. Release 2010, 147:304-310.
82. Li X., Anton N., Vandamme T.F. Spray-drying of nano- and microcapsules of nutraceuticals. Functional Food Ingredients and Neutraceuticals-Processing Technologies 2015, 455-480. CRC Press, Taylor & Francis Group, Boca Raton. J. Shi (Ed.).
83. Littringer E.M., Zellnitz S., Hammernik K., Adamer V., Friedl H., Urbanetz N.A. Spray drying of aqueous salbutamol sulfate solutions using the nano spray dryer b-90 - the impact of process parameters on particle size. Dry. Technol. 2013, 31:1346-1353.
84. Longest P.W., Golshahi L., Behara S.R.B., Tian G., Farkas D.R., Hindle M. Efficient nose-to-lung (N2L) aerosol delivery with a dry powder inhaler. J. Aerosol Med. Pulm. Drug Deliv. 2015, 28:189-201.
85. Maa Y.F., Nguyen P.A., Sit K., Hsu C.C. Spray-drying performance of a bench-top spray dryer for protein aerosol powder preparation. Biotechnol. Bioeng. 1998, 60:301-309.
86. Mahdavee Khazaei K., Jafari S.M., Ghorbani M., Hemmati Kakhki A. Application of maltodextrin and gum Arabic in microencapsulation of saffron petal's anthocyanins and evaluating their storage stability and color. Carbohydr. Polym. 2014, 105(1):57-62.
87. Mahdavi S.A., Jafari S.M., Ghorbani M., Assadpoor E. Spray-drying microencapsulation of anthocyanins by natural biopolymers: a review. Dry. Technol. 2014, 32:509-518.
88. Maltesen M.J., Bjerregaard S., Hovgaard L., Havelund S., van de Weert M. Quality by design-spray drying of insulin intended for inhalation. Eur. J. Pharm. Biopharm. 2008, 70:828-838.
89. Martena V., Censi R., Hoti E., Malaj L., Di Martino P. A new nanospray drying method for the preparation of nicergoline pure nanoparticles. J. Nanoparticle Res. 2012, 14:1-10.
90. Masters K. Spray drying handbook 1991, Longman Scientific & Technical, Harlow, USA. 5th edition.
91. Merchant Z., Taylor K.M.G., Stapleton P., Razak S.A., Kunda N., Alfagih I., Sheikh K., Saleem I.Y., Somavarapu S. Engineering hydrophobically modified chitosan for enhancing the dispersion of respirable microparticles of levofloxacin. Eur. J. Pharm. Biopharm. 2014, 88:816-829.
92. Mizuno A. Electrostatic precipitation. IEEE Trans. Dielectr. Electr. Insul. 2000, 7:615-624.
93. Moncada M., Astete C., Sabliov C., Olson D., Boeneke C., Aryana K.J. Nano spray-dried sodium chloride and its effects on the microbiological and sensory characteristics of surface-salted cheese crackers. J. Dairy Sci. 2015, 98:5946-5954.
94. Murugesan R., Orsat V. Spray drying for the production of nutraceutical ingredients-a review. Food Bioproc. Technol. 2012, 5:3-14.
95. Nandiyanto A.B.D., Okuyama K. Progress in developing spray-drying methods for the production of controlled morphology particles: from the nanometer to submicrometer size ranges. Adv. Powder Technol. 2011, 22:1-19.
96. Ngan L.T.K., Wang S.-L., Hiep D.M., Luong P.M., Vui N.T., Dinh T.M., Dzung N.A. Preparation of chitosan nanoparticles by spray drying, and their antibacterial activity. Res. Chem. Intermed. 2014, 40:2165-2175.
97. Okuyama K., Abdullah M., Lenggoro I.W., Iskandar F. Preparation of functional nanostructured particles by spray drying. Adv. Powder Technol. 2006, 17:587-611.
98. Oliveira A.M., Guimarães K.L., Cerize N.N., Tunussi A.S., Poço J.G. Nano spray drying as an innovative technology for encapsulating hydrophilic active pharmaceutical ingredients (API). J. Nanomed. Nanotechnol. 2013, 4:1-6.
99. öztürk, A.A., Yenilmez, E., Yazan, Y., 2015. Preparation and Characterization of Dexketoprofen Tromethamol Loaded Kollidon-SR Nanoparticles. In: ISOPS 11th International Symposium on Pharmaceutical Sciences, June 9-12, 2015, Ankara, Turkey.
100. Panda A., Meena J., Katara R., Majumdar D.K. Formulation and characterization of clozapine and risperidone co-entrapped spray-dried PLGA nanoparticles. Pharm. Dev. Technol. 2014, 7450:1-11.
101. Patel, R., Upadhyay, J.B., 2014. Nano Spray Dryer-A Technique to Handle Specific Products Range. In: National Seminar on "Indian Dairy Industry-Opportunities and Challenges", Technical Articles. pp. 181-183.
102. Perecin, C.J., Yoshioka, S.A., De Oliveira, A.M., Chitta, V.A., Cerize, N.N.P., 2014. Nanopartículas Superparamagnéticas Encapsuladas com Polímeros Para Aplicação No Tratamento De Câncer Por Hipertermia. In: XXIV, Congresso Brasiliero de Engenharia Biomédica, CBEB, pp., 2703-2706.
103. Perecin, C.J., Yoshioka, S., Chitta, V., Gratens, X., Léo, P., De Oliveira, A., Cerize, N., 2015. Magnetite Nanoparticles Encapsulated with PCL and Poloxamer by Nano Spray Drying technique. In: XIV, Brazil, MRS (Materials Research Society) Meeting, Rio, Awarded Abstract: ASEE, Symposium B.
104. Pérez-Masiá R., López-Nicolás R., Periago M.J., Ros G., Lagaron J.M., López-Rubio A. Encapsulation of folic acid in food hydrocolloids through nanospray drying and electrospraying for nutraceutical applications. Food Chem. 2015, 168:124-133.
105. Pourashouri P., Shabanpour B., Razavi S.H., Jafari S.M., Shabani A., Aubourg S.P. Impact of wall materials on physicochemical properties of microencapsulated fish oil by spray drying. Food Bioproc. Technol. 2014, 7:2354-2365.
106. Quintanilla-Carvajal M.X., Camacho-Díaz B.H., Meraz-Torres L.S., Chanona-Pérez J.J., Alamilla-Beltrán L., Jimenéz-Aparicio A., Gutiérrez-López G.F. Nanoencapsulation: a new trend in food engineering processing. Food Eng. Rev. 2010, 2:39-50.
107. Rajabi H., Ghorbani M., Jafari S.M., Mahoonak S.A., Rajabzadeh G. Retention of saffron bioactive components by spray drying encapsulation using maltodextrin, gum Arabic and gelatin as wall materials. Food Hydrocoll. 2015, 51:327-337.
108. Riehle C. Basic and theoretical operation of electrostatic precipitators. Applied Electrostatic Precipitation 1997, Blackie Academic & Professional, An Imprint of Chapman & Hall, London, UK, (Chapter 3). K.R. Parker (Ed.).
109. Sabliov C.M., Astete C.E. Polymeric nanoparticles for food applications. Nanotechnology and Functional Foods: Effective Delivery of Bioactive Ingredients 2015, 272-296. John Wiley & Sons, Ltd., Chichester, UK, (Chapter 17). C.M. Sabliov, H. Chen, Y.R. Y. (Eds.).
110. Sarma S.J., Brar S.K., Reigner J., Le Bihan Y., Buelna G. Enriched hydrogen production by bioconversion of biodiesel waste supplemented with ferric citrate and its nano-spray dried particles. RSC Adv. 2014, 4:49588-49594.
111. Sarma S.J., Das R.K., Brar S.K., Le Bihan Y., Buelna G., Verma M., Soccol C.R. Application of magnesium sulfate and its nanoparticles for enhanced lipid production by mixotrophic cultivation of algae using biodiesel waste. Energy 2014, 78:16-22.
112. Schafroth N., Arpagaus C., Jadhav U.Y., Makne S., Douroumis D. Nano and microparticle engineering of water insoluble drugs using a novel spray-drying process. Colloids Surf. B Biointerfaces 2012, 90:8-15.
113. Schmid, K., 2011. Spray drying of protein precipitates and Evaluation of the Nano Spray Dryer B-90. PhD Thesis, Ludwig-Maximilians-University, Munich.
114. Schmid K., Arpagaus C., Friess W. Evaluation of a vibrating mesh spray dryer for preparation of submicron particles. Respir. Drug Deliv. Eur. 2009, 2:323-326.
115. Schmid K., Arpagaus C., Friess W. Evaluation of the nano spray dryer B-90 for pharmaceutical applications. Pharm. Dev. Technol. 2011, 16:287-294.
116. Schön, M., Baumgartner, R., 2009. Method for Heating and Laminating, Electrostatic Separator, Spray Drier, Separating Device and Method for Separating Particles. Patent EP 2056037 (A1), priority date: 2007-10-30.
117. Schoubben A., Blasi P., Marenzoni M.L., Barberini L., Giovagnoli S., Cirotto C., Ricci M. Capreomycin supergenerics for pulmonary tuberculosis treatment: preparation, in vitro, and in vivo characterization. Eur. J. Pharm. Biopharm. 2013, 83:388-395.
118. Schoubben A., Giovagnoli S., Tiralti M.C., Blasi P., Ricci M. Capreomycin inhalable powders prepared with an innovative spray-drying technique. Int. J. Pharm. 2014, 469:132-139.
119. Schoubben A., Blasi P., Giontella A., Giovagnoli S., Ricci M. Powder, capsule and device: an imperative ménage à trois for respirable dry powders. Int. J. Pharm. 2015, 494:40-48.
120. Schultz I., Vollmers F., Lühmann T., Rybak J.-C., Wittmann R., Stank K., Steckel H., Kardziev B., Schmidt M., Högger P., Meinel L. Pulmonary insulin-like growth factor I delivery from trehalose and silk-fibroin microparticles. ACS Biomater. Sci. Eng. 2015, 1:119-129.
121. Smart J., Berg E., Nerbrink O., Zuban R., Blakey D., New M., Mastersizer M. TouchSpray technology: comparison of the droplet size with cascade impaction and laser diffraction. Respir. Drug Deliv. 2002, VIII 2:525-528.
122. Son Y.-J., Longest P.W., Hindle M. Aerosolization characteristics of dry powder inhaler formulations for the excipient enhanced growth (EEG) application: effect of spray drying process conditions on aerosol performance. Int. J. Pharm. 2013, 443:137-145.
123. Son Y.-J., Longest P.W., Tian G., Hindle M. Evaluation and modification of commercial dry powder inhalers for the aerosolization of a submicrometer excipient enhanced growth (EEG) formulation. Eur. J. Pharm. Sci. 2013, 49:390-399.
124. Sosnik A., Seremeta K.P. Advantages and challenges of the spray-drying technology for the production of pure drug particles and drug-loaded polymeric carriers. Adv. Colloid Interface Sci. 2015, 223:40-54.
125. Sun Y., Song X., Wang J., Yu J. Preparation of lithium carbonate hollow spheres by spray pyrolysis. Cryst. Res. Technol. 2011, 46:173-177.
126. 4, Pt-thin-film composite electrodes for solid acid fuel cells. RSC Adv. 2014, 4:60429-60436.
127. Vecellio L. The mesh nebulizer: a recent technical innovation for aerosol delivery. Breathe 2006, 2:252-260.
128. Vehring R. Pharmaceutical particle engineering via spray drying. Pharm. Res. 2008, 25:999-1022.
129. Wang B., Zhang W., Zhang W., Mujumdar A.S., Huang L. Progress in drying technology for nanomaterials. Dry. Technol. 2005, 23:7-32.
130. Whelehan, M., 2014. Encapsulator B-390/ B-395 Pro-Laboratory Guide, Büchi Labortechnik AG, No. 11595052 en 1408 A.
131. Whelehan M., Marison I.W. Microencapsulation using vibrating technology. J. Microencapsul. 2011, 28:669-688.
132. Wong T.W., John P. Advances in spray drying technology for nanoparticle formation. Handbook of Nanoparticles 2015, 1-16. Springer International Publishing, Cham, Switzerland. M. Aliofkhazraei (Ed.).
133. Zellnitz S., Schroettner H., Urbanetz N.A. Surface modified glass beads as model carriers in dry powder inhalers-influence of drug load on the fine particle fraction. Powder Technol. 2014, 268:377-386.
134. Zellnitz S., Narygina O., Resch C., Schroettner H., Urbanetz N.A. Crystallization speed of salbutamol as a function of relative humidity and temperature. Int. J. Pharm. 2015, 489:170-176.
135. Zellnitz S., Schroettner H., Urbanetz N.A. Influence of surface characteristics of modified glass beads as model carriers in dry powder inhalers (DPIs) on the aerosolization performance. Drug Dev. Ind. Pharm. 2015, 41:1710-1717.
136. Feng S.-S., Mu L., Win K.Y., Huang G. Nanoparticles of biodegradable polymers for clinical administration of paclitaxel. Curr. Med. Chem. 2004, 11:413-424.