Mechanistic models facilitate efficient development of leucine containing microparticles for pulmonary drug delivery

International Journal of Pharmaceutics

Volumn 409, Issue 1-2, 2011, Pages 156-163

  Feng, A L ^a   Boraey, M A ^a   Gwin, M A ^a   Finlay, P R ^a   Kuehl, P J ^b   Vehring, R ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

Crystallinity; Dispersibility; Particle engineering; Powder density; Respiratory drug delivery; Spray drying

Indexed keywords

CRYSTALLIN; DRUG CARRIER; DRUG VEHICLE; EXCIPIENT; LEUCINE; MICROPARTICLE; TREHALOSE; UNCLASSIFIED DRUG;

AEROSOL; ARTICLE; BULK DENSITY; CRYSTALLIZATION; DISPERSION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; EVAPORATION; FEASIBILITY STUDY; MORPHOLOGY; PARTICLE SIZE; POWDER; PRIORITY JOURNAL; PULMONARY DRUG DELIVERY; RAMAN SPECTROMETRY; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; TIME OF FLIGHT MASS SPECTROMETRY;

AEROSOLS; CRYSTALLIZATION; DRUG DELIVERY SYSTEMS; EXCIPIENTS; LEUCINE; LUNG; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MODELS, THEORETICAL; SPECTRUM ANALYSIS, RAMAN; TIME FACTORS; TREHALOSE;

EID: 79954989284     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.02.049     Document Type: Article

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