-
1
-
-
0025102704
-
The molecular basis of moisture effects on the physical and chemical stability of drugs in the solid state
-
DOI 10.1016/0378-5173(90)90221-O
-
C Ahlneck G Zografi 1990 The molecular basis of moisture effects on the physical and chemical stability of drugs in the solid state Int J Pharm 62 87 95 10.1016/0378-5173(90)90221-O 1:CAS:528:DyaK3cXlslyjurg%3D (Pubitemid 20261777)
-
(1990)
International Journal of Pharmaceutics
, vol.62
, Issue.2-3
, pp. 87-95
-
-
Ahlneck, C.1
Zografi, G.2
-
2
-
-
0031056536
-
Effects of sorbed water on the crystallization of indomethacin from the amorphous state
-
DOI 10.1021/js9602711
-
V Andronis M Yoshioka G Zografi 1997 Effects of sorbed water on the crystallization of indomethacin from the amorphous state J Pharm Sci 86 346 351 10.1021/js9602711 1:CAS:528:DyaK2sXhtVGhtrs%3D (Pubitemid 27113770)
-
(1997)
Journal of Pharmaceutical Sciences
, vol.86
, Issue.3
, pp. 346-357
-
-
Andronis, V.1
Yoshioka, M.2
Zografi, G.3
-
5
-
-
0036786457
-
Water vapour absorption into amorphous hydrophobic drug/ poly(vinylpyrrolidone) dispersions
-
10.1002/jps.10205
-
KJ Crowley G Zografi 2002 Water vapour absorption into amorphous hydrophobic drug/poly(vinylpyrrolidone) dispersions J Pharm Sci 90 2150 2165 10.1002/jps.10205
-
(2002)
J Pharm Sci
, vol.90
, pp. 2150-2165
-
-
Crowley, K.J.1
Zografi, G.2
-
6
-
-
0037381525
-
Droplet and particle size relationship and shell thickness of inhalable lactose particles during spray drying
-
DOI 10.1002/jps.10352
-
J Elversson A Millqvist-Fureby G Alderborn U Eloffson 2003 Droplet and particle size relationship and shell thickness of inhalable lactose particles during spray drying J Pharm Sci 92 900 910 10.1002/jps.10352 1:CAS:528:DC%2BD3sXislOgsLs%3D (Pubitemid 36397005)
-
(2003)
Journal of Pharmaceutical Sciences
, vol.92
, Issue.4
, pp. 900-910
-
-
Elversson, J.1
Millqvist-Fureby, A.2
Alderborn, G.3
Elofsson, U.4
-
7
-
-
42549152846
-
Drug nanocrystals for the formulation of poorly soluble drugs and its application as a potential drug delivery system
-
10.1007/s11051-008-9357-4 1:CAS:528:DC%2BD1cXkvFajsbg%3D
-
L Gao D Zhang M Chen 2008 Drug nanocrystals for the formulation of poorly soluble drugs and its application as a potential drug delivery system J Nanopart Res 10 845 862 10.1007/s11051-008-9357-4 1:CAS:528:DC%2BD1cXkvFajsbg%3D
-
(2008)
J Nanopart Res
, vol.10
, pp. 845-862
-
-
Gao, L.1
Zhang, D.2
Chen, M.3
-
8
-
-
0024155431
-
Comparison of the effects of vinpocentine, vincamine, and nicergoline on the normal and hypoxia-damaged learning process in spontaneously hypertensive rats
-
DOI 10.1002/ddr.430150108
-
D Goo E Palosi L Szporny 1988 Comparison of the effects of vinpocetine, vincamine, and nicergoline on the normal and hypoxia-damaged learning process in spontaneously hypertensive rats Drug Dev Res 15 75 85 10.1002/ddr.430150108 (Pubitemid 19159185)
-
(1988)
Drug Development Research
, vol.15
, Issue.1
, pp. 75-85
-
-
Groo, D.1
Palosi, E.2
Szporny, L.3
-
9
-
-
0032719278
-
Interaction between water and poly(vinylpyrrolidone) containing polyethylene glycol
-
DOI 10.1021/js980354c
-
T Hamaura JM Newton 1999 Interaction between water and poly(vinylpyrrolidone) containing polyethylene glycol J Pharm Sci 88 1228 1232 10.1021/js980354c 1:CAS:528:DyaK1MXmtlCksro%3D (Pubitemid 29526311)
-
(1999)
Journal of Pharmaceutical Sciences
, vol.88
, Issue.11
, pp. 1228-1233
-
-
Hamaura, T.1
Newton, J.M.2
-
10
-
-
1142303337
-
What is the true solubility advantage for amorphous pharmaceuticals?
-
DOI 10.1023/A:1007516718048
-
BC Hancock M Parks 2000 What is the true solubility advantage for amorphous pharmaceuticals? Pharm Res 17 397 403 10.1023/A:1007516718048 1:CAS:528:DC%2BD3cXktFalsb0%3D (Pubitemid 30395293)
-
(2000)
Pharmaceutical Research
, vol.17
, Issue.4
, pp. 397-404
-
-
Hancock, B.C.1
Parks, M.2
-
11
-
-
0022455325
-
α-Adrenoceptor antagonistic and calcium antagonistic effects of nicergoline in the rat isolated aorta
-
C Heitz JJ Descombes RC Miller JC Stoclet 1986 α-Adrenoceptor antagonistic and calcium antagonistic effects of nicergoline in the rat isolated aorta Eur J Pharmacol 123 279 285 10.1016/0014-2999(86)90669-2 1:CAS:528:DyaL28XktFyht7c%3D (Pubitemid 16055461)
-
(1986)
European Journal of Pharmacology
, vol.123
, Issue.2
, pp. 279-285
-
-
Heitz, C.1
Descombes, J.-J.2
Miller, R.C.3
Stoclet, J.-C.4
-
12
-
-
84865702548
-
Stability testing of new drug substances and products. Note for guidance on stability testing: Stability testing of new drug substances and products. (CPMP/ICH/2736/99)
-
ICH Topic Q 1 A (R2) London
-
ICH Topic Q 1 A (R2) (2003) Stability testing of new drug substances and products. Note for guidance on stability testing: stability testing of new drug substances and products. (CPMP/ICH/2736/99). EMEA, London, pp 1-20
-
(2003)
EMEA
, pp. 1-20
-
-
-
13
-
-
69749103682
-
Nanocrystal technology, drug delivery and clinical applications
-
1:CAS:528:DC%2BD1cXhtlems7jF
-
JAH Junghanns RH Müller 2008 Nanocrystal technology, drug delivery and clinical applications Int J Nanomed 3 295 309 1:CAS:528:DC%2BD1cXhtlems7jF
-
(2008)
Int J Nanomed
, vol.3
, pp. 295-309
-
-
Junghanns, J.A.H.1
Müller, R.H.2
-
15
-
-
0033043629
-
Protein inhalation powders: Spray drying vs spray freeze drying
-
YF Maa PA Nguyen T Sweeney SJ Shire CC Hsu 1999 Protein inhalation powders: spray drying vs spray freeze drying Pharm Res 16 249 254 10.1023/A:1018828425184 1:CAS:528:DyaK1MXhvFyltr4%3D (Pubitemid 29135129)
-
(1999)
Pharmaceutical Research
, vol.16
, Issue.2
, pp. 249-254
-
-
Maa, Y.-F.1
Nguyen, P.-A.2
Sweeney, T.3
Shire, S.J.4
Hsu, C.5
-
16
-
-
79955636924
-
Characterization of nicergoline polymorphs crystallized in several organic solvents
-
10.1002/jps.22477 1:CAS:528:DC%2BC3MXlslCgs7o%3D
-
L Malaj R Censi D Capsoni L Pellegrino M Bini S Ferrari R Gobetto V Massarotti P Di Martino 2011 Characterization of nicergoline polymorphs crystallized in several organic solvents J Pharm Sci 100 2610 2622 10.1002/jps.22477 1:CAS:528:DC%2BC3MXlslCgs7o%3D
-
(2011)
J Pharm Sci
, vol.100
, pp. 2610-2622
-
-
Malaj, L.1
Censi, R.2
Capsoni, D.3
Pellegrino, L.4
Bini, M.5
Ferrari, S.6
Gobetto, R.7
Massarotti, V.8
Di Martino, P.9
-
17
-
-
84858078659
-
Physicochemical characterization of nicergoline and cabergoline in its amorphous state
-
doi: 10.1007/s10973-011-1954-2
-
Martena V, Censi R, Hoti E, Malaj L, Di Martino P (2011) Physicochemical characterization of nicergoline and cabergoline in its amorphous state. J Therm Anal Calorim doi: 10.1007/s10973-011-1954-2
-
(2011)
J Therm Anal Calorim
-
-
Martena, V.1
Censi, R.2
Hoti, E.3
Malaj, L.4
Di Martino, P.5
-
18
-
-
61349095957
-
Development of an oral rutin nanocrystal formulation
-
10.1016/j.ijpharm.2008.11.029 1:CAS:528:DC%2BD1MXislKisbY%3D
-
R Mauludin RH Müller CM Keck 2009 Development of an oral rutin nanocrystal formulation Int J Pharm 370 202 209 10.1016/j.ijpharm.2008.11.029 1:CAS:528:DC%2BD1MXislKisbY%3D
-
(2009)
Int J Pharm
, vol.370
, pp. 202-209
-
-
Mauludin, R.1
Müller, R.H.2
Keck, C.M.3
-
19
-
-
35748978732
-
Nanocrystals: Resolving pharmaceutical formulation issues associated with poorly water-soluble compounds
-
Marty JJ (Ed) Orlando
-
Merisko-Liversidge E (2002) Nanocrystals: resolving pharmaceutical formulation issues associated with poorly water-soluble compounds. In: Marty JJ (Ed) Particles. Marcel Dekker, Orlando
-
(2002)
Particles. Marcel Dekker
-
-
Merisko-Liversidge, E.1
-
20
-
-
33947487639
-
The rate of solution of solid substances in their own solutions
-
10.1021/ja02086a003
-
A Noyes WR Whitney 1897 The rate of solution of solid substances in their own solutions J Am Chem Soc 19 930 934 10.1021/ja02086a003
-
(1897)
J Am Chem Soc
, vol.19
, pp. 930-934
-
-
Noyes, A.1
Whitney, W.R.2
-
21
-
-
0023797398
-
Effect of hypoxia, aging and pharmacological treatment on muscular metabolites and enzyme activities
-
O Pastoris L Vercesi F Allorio M Dossena 1988 Effect of hypoxia, aging and pharmacological treatment on muscular metabolites and enzyme activities Il Farmaco Ed Sci 43 627 642 1:CAS:528:DyaL1cXmt1Ontb0%3D (Pubitemid 18261466)
-
(1988)
Farmaco, Edizione Scientifica
, vol.43
, Issue.7-8
, pp. 627-642
-
-
Pastoris, O.1
Vercesi, L.2
Allorio, F.3
Dossena, M.4
-
22
-
-
0029807935
-
Moisture-dependent crystallization of amorphous lamotrigine mesylate
-
DOI 10.1021/js9600484
-
E Schmitt CW Davis ST Long 1996 Moisture-dependent crystallization of amorphous lamotrigine mesylate J Pharm Sci 85 1215 1219 10.1021/js9600484 1:CAS:528:DyaK28XmtFKisrw%3D (Pubitemid 26372891)
-
(1996)
Journal of Pharmaceutical Sciences
, vol.85
, Issue.11
, pp. 1215-1219
-
-
Schmitt, E.1
Davis, C.W.2
Long, S.T.3
-
23
-
-
0032784693
-
The effects of absorbed water on the properties of amorphous mixtures containing sucrose
-
DOI 10.1023/A:1018960405504
-
SL Shamblin G Zografi 1999 The effects of absorbed water on the properties of amorphous mixtures containing sucrose Pharm Res 16 1119 1124 10.1023/A:1018960405504 1:CAS:528:DyaK1MXltVyhsLw%3D (Pubitemid 29368163)
-
(1999)
Pharmaceutical Research
, vol.16
, Issue.7
, pp. 1119-1124
-
-
Shamblin, S.L.1
Zografi, G.2
-
24
-
-
77956882799
-
Nanocrystals: Industrially feasible multifunctional formulation technology for poorly soluble actives
-
10.1016/j.ijpharm.2010.07.044 1:CAS:528:DC%2BC3cXhtFOisbzM
-
R Shegokar RH Müller 2010 Nanocrystals: industrially feasible multifunctional formulation technology for poorly soluble actives Int J Pharm 399 129 139 10.1016/j.ijpharm.2010.07.044 1:CAS:528:DC%2BC3cXhtFOisbzM
-
(2010)
Int J Pharm
, vol.399
, pp. 129-139
-
-
Shegokar, R.1
Müller, R.H.2
-
25
-
-
0002820601
-
Poorly soluble drugs: A challenge in drug delivery
-
S. Benita B. Böhm R.H. Müller (eds). Medpharm Scientific Publishers Stuttgart
-
Speiser PP (1998) Poorly soluble drugs: a challenge in drug delivery. In: Benita S, Böhm B, Müller RH (eds) Emulsions and nanosuspensions for the formulation of poorly soluble drugs. Medpharm Scientific Publishers, Stuttgart, pp 15-28
-
(1998)
Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs.
, pp. 15-28
-
-
Speiser, P.P.1
-
26
-
-
84865802307
-
Amorphous solids
-
H.G. Brittain (eds). Informa Healthcare New York
-
Taylor LS, Shamblin SL (2009) Amorphous solids. In: Brittain HG (ed) Polymorphism. Informa Healthcare, New York, pp 594-596
-
(2009)
Polymorphism
, pp. 594-596
-
-
Taylor, L.S.1
Shamblin, S.L.2
-
27
-
-
0019847616
-
Use of nicergoline in acute myocardial infarction with diastolic hypertension
-
E Triulzi S Devizzi A Margonato 1981 Use of nicergoline in acute myocardial infarction with diastolic hypertension Il Farmaco (ed Prat) 36 449 455 1:STN:280:DyaL38%2FntlWnsA%3D%3D (Pubitemid 12179228)
-
(1981)
Farmaco, Edizione Pratica
, vol.36
, Issue.10
, pp. 449-455
-
-
Triulzi, E.1
Devizzi, S.2
Margonato, A.3
-
28
-
-
0018813337
-
Review of clinical studies with ergots in gerontology
-
M. Goldstein A. Liberman D.B. Calne M.O. Thorner (eds). Raven Press New York
-
Venn RD (1980) Review of clinical studies with ergots in gerontology. In: Goldstein M, Liberman A, Calne DB, Thorner MO (eds) Ergot compounds and brain function. Raven Press, New York, pp 363-377
-
(1980)
Ergot Compounds and Brain Function
, pp. 363-377
-
-
Venn, R.D.1
-
29
-
-
0023761049
-
States of water associated with solids
-
10.3109/03639048809151997 1:CAS:528:DyaL1cXlvFOktbk%3D
-
G Zografi 1988 States of water associated with solids Drug Dev Ind Pharm 14 1905 1926 10.3109/03639048809151997 1:CAS:528:DyaL1cXlvFOktbk%3D
-
(1988)
Drug Dev Ind Pharm
, vol.14
, pp. 1905-1926
-
-
Zografi, G.1
|