Optimization of CoaD Inhibitors against Gram-Negative Organisms through Targeted Metabolomics

ACS Infectious Diseases

Volumn 4, Issue 3, 2018, Pages 391-402

  Rath, Christopher M ^a   Benton, Bret M ^a   De Vicente, Javier ^a   Drumm, Joseph E ^a   Geng, Mei ^a   Li, Cindy ^a   Moreau, Robert J ^a   Shen, Xiaoyu ^a   Skepper, Colin K ^a   Steffek, Micah ^a   Takeoka, Kenneth ^a   Wang, Lisha ^a   Wei, Jun Rong ^a   Xu, Wenjian ^a   Zhang, Qiong ^a   Feng, Brian Y ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; COAD INHIBITOR; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; NUCLEOTIDYLTRANSFERASE; PANTETHEINE-PHOSPHATE ADENYLYLTRANSFERASE;

ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; GROWTH INHIBITION; KLEBSIELLA PNEUMONIAE; MASS SPECTROMETRY; METABOLOMICS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; WILD TYPE; ANTAGONISTS AND INHIBITORS; DRUG EFFECT; ENZYMOLOGY; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; PROCEDURES; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTI-BACTERIAL AGENTS; ESCHERICHIA COLI; MASS SPECTROMETRY; METABOLOMICS; MICROBIAL SENSITIVITY TESTS; NUCLEOTIDYLTRANSFERASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 85043458027     PISSN: None     EISSN: 23738227     Source Type: Journal    
DOI: 10.1021/acsinfecdis.7b00214     Document Type: Article

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