Engineering posttranslational proofreading to discriminate nonstandard amino acids

Proceedings of the National Academy of Sciences of the United States of America

Volumn 115, Issue 3, 2018, Pages 619-624

  Kunjapur, Aditya M ^a   Stork, Devon A ^a   Kuru, Erkin ^a   Vargas Rodriguez, Oscar ^b   Landon, Matthieu ^a   Söll, Dieter ^b   Church, George M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

Amino acids; Genetic code expansion; N end rule; Nonstandard; Protein degradation; Synthetic biology

Indexed keywords

AMINO ACID; BACTERIAL PROTEIN; BACTERIAL PROTEIN CLPS; NONSTANDARD AMINO ACID; PHENYLALANINE; TYROSINE TRANSFER RNA; TYROSINE TRANSFER RNA LIGASE; UNCLASSIFIED DRUG; AMINOBIPHENYL DERIVATIVE; ARCHAEAL PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL GROWTH; ESCHERICHIA COLI; IN VITRO STUDY; IN VIVO STUDY; METHANOCALDOCOCCUS JANNASCHII; MOLECULAR RECOGNITION; NONHUMAN; POSTTRANSLATIONAL PROOFREADING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN ENGINEERING; PROTEIN PROCESSING; QUALITY CONTROL PROCEDURES; SACCHAROMYCES CEREVISIAE; ENZYMOLOGY; GENETICS; METABOLISM; METHANOCALDOCOCCUS; PROTEIN SYNTHESIS;

AMINO ACIDS; AMINOBIPHENYL COMPOUNDS; ARCHAEAL PROTEINS; ESCHERICHIA COLI; METHANOCALDOCOCCUS; PROTEIN BIOSYNTHESIS; PROTEIN ENGINEERING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; TYROSINE-TRNA LIGASE;

EID: 85040566246     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1715137115     Document Type: Article

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