ClpS, a substrate modulator of the ClpAP machine

Molecular Cell

Volumn 9, Issue 3, 2002, Pages 673-683

  Dougan, David A ^a   Reid, Brian G ^b   Horwich, Arthur L ^b   Bukau, Bernd ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHAPERONE; LUCIFERASE; PROTEASE CLPAP; PROTEASE CLPS; PROTEINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; CYTOSOL; DNA SEQUENCE; ENZYME SPECIFICITY; ESCHERICHIA COLI; IN VITRO STUDY; NONHUMAN; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN INTERACTION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0036210995     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(02)00485-9     Document Type: Article

References (34)

1. The structures of HsIU and the ATP-dependent protease HsIU-HsIV
2. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
3. Overlapping recognition determinants within the ssrA degradation tag allow modulation of proteolysis
4. Sequential mechanism of solubilization and refolding of stable protein aggregates by a bichaperone network
5. Subunit-specific degradation of the UmuD/D′ heterodimer by the ClpXP protease: The role of trans recognition in UmuD′ stability
6. Regulation by proteolysis: Developmental switches
7. The ATP-dependent Clp protease of Escherichia coli. Sequence of clpA and identification of a Clp-specific substrate
8. ClpX, an alternative subunit for the ATP-dependent Clp protease of Escherichia coli. Sequence and in vivo activities
9. The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system
10. Substrate recognition by the ClpA chaperone component of ClpAP protease
11. Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA
12. p47 is a cofactor for p97-mediated membrane fusion
13. A specificity-enhancing factor for the ClpXP degradation machine
14. Characterization of the N-terminal repeat domain of Escherichia coli ClpA-A class I Clp/HSP100 ATPase
15. A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways
16. Identification of thermolabile Escherichia coli proteins: Prevention and reversion of aggregation by DnaK and ClpB
17. Heat-inactivated proteins are rescued by the DnaK.J-GrpE set and ClpB chaperones
18. The response regulator RssB controls stability of the sigma(S) subunit of RNA polymerase in Escherichia coli
19. Aaa+: A class of chaperone-like atpases associated with the assembly, operation, and disassembly of protein complexes
20. The response regulator SprE controls the stability of RpoS
21. ClpA mediates directional translocation of substrate proteins into the ClpP protease
22. A major conformational change in p97 AAA ATPase upon ATP binding
23. DnaK, DnaJ and GrpE form a cellular chaperone machinery capable of repairing heat-induced protein damage
24. Lon and Clp family proteases and chaperones share homologous substrate-recognition domains
25. Crystal and solution structures of an HslUV protease-chaperone complex
26. The N-end rule in bacteria
27. Biochemical characterization of a molecular switch involving the heat shock protein ClpC, which controls the activity of ComK, the competence transcription factor of Bacillus subtilis
28. Competence in Bacillus subtilis is controlled by regulated proteolysis of a transcription factor
29. The structure of ClpP at 2.3 Å resolution suggests a model for ATP-dependent proteolysis
30. Global unfolding of a substrate protein by the Hsp100 chaperone ClpA
31. A molecular chaperone, ClpA, functions like DnaK and DnaJ
32. Posttranslational quality control: Folding, refolding, and degrading proteins
33. Isolation and characterization of ClpX, a new ATP-dependent specificity component of the Clp protease of Escherichia coli
34. S for degradation by ClpXP