-
1
-
-
0003472502
-
-
5th edn. Arlington, VA: American Psychiatric Association, xliv
-
American Psychiatric Association. Diagnostic and statistical manual of mental disorders: DSM-5. 5th edn. Arlington, VA: American Psychiatric Association; 2013., xliv, p. 947.
-
(2013)
Diagnostic and Statistical Manual of Mental Disorders: DSM-5
, pp. 947
-
-
-
2
-
-
85062050627
-
-
Studien uber Vererbung und entstehung geistiger Storungen. I. Zur vererbung und neuentstehung der Dementia praecox, Monographien aus dem Gesamtgebiet der Neurologie und Psychiatrie, Number 12. Berlin, Springer
-
Rudin E. Studien uber Vererbung und entstehung geistiger Storungen. I. Zur vererbung und neuentstehung der Dementia praecox (Studies on the inheritance and origin of mental illness. I. The problem of the inheritance and primary origin of dementia praecox). Monographien aus dem Gesamtgebiet der Neurologie und Psychiatrie, Number 12. Berlin: Springer; 1916.
-
(1916)
Studies on the Inheritance and Origin of Mental Illness. I. the Problem of the Inheritance and Primary Origin of Dementia Praecox
-
-
Rudin, E.1
-
3
-
-
52449136362
-
Vorlaufiger Bericht uder psychiatrische Serienuntersuchungen und Zwillingen
-
Luxenburger H. Vorlaufiger Bericht uder psychiatrische Serienuntersuchungen und Zwillingen. Z Gesamt Neurol Psychiatr. 1928;116:297–326.
-
(1928)
Z Gesamt Neurol Psychiatr
, vol.116
, pp. 297-326
-
-
Luxenburger, H.1
-
4
-
-
0013937338
-
Psychiatric disorder in foster home reared children of schizophrenic mothers
-
COI: 1:STN:280:DyaF2s7mslWisA%3D%3D, PID: 5966555
-
Heston LL. Psychiatric disorder in foster home reared children of schizophrenic mothers. Br J Psychiatry. 1966;112:819–25.
-
(1966)
Br J Psychiatry
, vol.112
, pp. 819-825
-
-
Heston, L.L.1
-
5
-
-
33645955013
-
-
Arlington, VA, American Psychiatric Publishing, Inc
-
Kendler KS, Eaves LJ. Psychiatric genetics, review of psychiatry, Vol 24. Arlington, VA: American Psychiatric Publishing, Inc.; 2005.
-
(2005)
Psychiatric Genetics, Review of Psychiatry, Vol 24
-
-
Kendler, K.S.1
Eaves, L.J.2
-
6
-
-
0035168444
-
Twin studies of psychiatric illness: an update
-
COI: 1:STN:280:DC%2BD38%2FivVGktw%3D%3D, PID: 11695946
-
Kendler KS. Twin studies of psychiatric illness: an update. Arch Gen Psychiatry. 2001;58:1005–14.
-
(2001)
Arch Gen Psychiatry
, vol.58
, pp. 1005-1014
-
-
Kendler, K.S.1
-
7
-
-
0141567810
-
The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women
-
PID: 12963675
-
Kendler KS, Prescott CA, Myers J, Neale MC. The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Arch Gen Psychiatry. 2003;60:929–37.
-
(2003)
Arch Gen Psychiatry
, vol.60
, pp. 929-937
-
-
Kendler, K.S.1
Prescott, C.A.2
Myers, J.3
Neale, M.C.4
-
8
-
-
0023514436
-
The significance of genetic factors in the etiology of schizophrenia: results from the national study of adoptees in Denmark
-
COI: 1:STN:280:DyaL1c7lsFCmug%3D%3D, PID: 3440955
-
Kety SS. The significance of genetic factors in the etiology of schizophrenia: results from the national study of adoptees in Denmark. J Psychiatr Res. 1987;21:423–9.
-
(1987)
J Psychiatr Res
, vol.21
, pp. 423-429
-
-
Kety, S.S.1
-
9
-
-
0033793503
-
Adoptive and biological families of children and adolescents with ADHD
-
COI: 1:STN:280:DC%2BD3crhtFKntg%3D%3D, PID: 11068899
-
Sprich S, Biederman J, Crawford MH, Mundy E, Faraone SV. Adoptive and biological families of children and adolescents with ADHD. J Am Acad Child Adolesc Psychiatry. 2000;39:1432–7.
-
(2000)
J Am Acad Child Adolesc Psychiatry
, vol.39
, pp. 1432-1437
-
-
Sprich, S.1
Biederman, J.2
Crawford, M.H.3
Mundy, E.4
Faraone, S.V.5
-
10
-
-
84924650670
-
The heritability of alcohol use disorders: a meta-analysis of twin and adoption studies
-
COI: 1:STN:280:DC%2BC2M%2Fmt1Olsg%3D%3D
-
Verhulst B, Neale MC, Kendler KS. The heritability of alcohol use disorders: a meta-analysis of twin and adoption studies. Psychol Med. 2015;45:1061–72.
-
(2015)
Psychol Med
, vol.45
, pp. 1061-1072
-
-
Verhulst, B.1
Neale, M.C.2
Kendler, K.S.3
-
11
-
-
78349235232
-
The structure of genetic and environmental risk factors for syndromal and subsyndromal common DSM-IV axis I and all axis II disorders
-
Kendler KS, Aggen SH, Knudsen GP, Roysamb E, Neale MC, Reichborn-Kjennerud T. The structure of genetic and environmental risk factors for syndromal and subsyndromal common DSM-IV axis I and all axis II disorders. Am J Psychiatry. 2011;168:29–39.
-
(2011)
Am J Psychiatry
, vol.168
, pp. 29-39
-
-
Kendler, K.S.1
Aggen, S.H.2
Knudsen, G.P.3
Roysamb, E.4
Neale, M.C.5
Reichborn-Kjennerud, T.6
-
12
-
-
68449086236
-
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
-
COI: 1:CAS:528:DC%2BD1MXotVSgtLg%3D
-
Purcell SM, Wray NR, Stone JL, Visscher PM, O’Donovan MC, et al. International Schizophrenia Consortium Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature. 2009;460:748–52.
-
(2009)
Nature
, vol.460
, pp. 748-752
-
-
Purcell, S.M.1
Wray, N.R.2
Stone, J.L.3
Visscher, P.M.4
O’Donovan, M.C.5
-
13
-
-
68449090594
-
Common variants conferring risk of schizophrenia
-
COI: 1:CAS:528:DC%2BD1MXotVSns74%3D, PID: 3077530
-
Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, et al. Common variants conferring risk of schizophrenia. Nature. 2009;460:744–7.
-
(2009)
Nature
, vol.460
, pp. 744-747
-
-
Stefansson, H.1
Ophoff, R.A.2
Steinberg, S.3
Andreassen, O.A.4
Cichon, S.5
Rujescu, D.6
-
14
-
-
49949085933
-
Large recurrent microdeletions associated with schizophrenia
-
COI: 1:CAS:528:DC%2BD1cXhtV2qtL%2FL, PID: 2687075
-
Stefansson H, Rujescu D, Cichon S, Pietilainen OP, Ingason A, Steinberg S, et al. Large recurrent microdeletions associated with schizophrenia. Nature. 2008;455:232–6.
-
(2008)
Nature
, vol.455
, pp. 232-236
-
-
Stefansson, H.1
Rujescu, D.2
Cichon, S.3
Pietilainen, O.P.4
Ingason, A.5
Steinberg, S.6
-
15
-
-
51649107017
-
Rare chromosomal deletions and duplications increase risk of schizophrenia
-
International Schizophrenia Consortium. Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature. 2008;455:237–41.
-
(2008)
Nature
, vol.455
, pp. 237-241
-
-
-
16
-
-
66149185456
-
Genomewide association studies: history, rationale, and prospects for psychiatric disorders
-
Psychiatric GWAS Consortium Coordinating Committee. Genomewide association studies: history, rationale, and prospects for psychiatric disorders. Am J Psychiatry. 2009;166:540–56.
-
(2009)
Am J Psychiatry
, vol.166
, pp. 540-556
-
-
-
17
-
-
85026709756
-
10 Years of GWAS Discovery: biology, function, and translation
-
COI: 1:CAS:528:DC%2BC2sXhtFChu7rI, PID: 5501872
-
Visscher PM, Wray NR, Zhang Q, Sklar P, McCarthy MI, Brown MA, et al. 10 Years of GWAS Discovery: biology, function, and translation. Am J Hum Genet. 2017;101:5–22.
-
(2017)
Am J Hum Genet
, vol.101
, pp. 5-22
-
-
Visscher, P.M.1
Wray, N.R.2
Zhang, Q.3
Sklar, P.4
McCarthy, M.I.5
Brown, M.A.6
-
18
-
-
84904804929
-
Biological insights from 108 schizophrenia-associated genetic loci
-
Schizophrenia Working Group of the Psychiatric Genomics C. Biological insights from 108 schizophrenia-associated genetic loci. Nature. 2014;511:421–7.
-
(2014)
Nature
, vol.511
, pp. 421-427
-
-
-
19
-
-
84908121749
-
Research review: Polygenic methods and their application to psychiatric traits
-
Wray NR, Lee SH, Mehta D, Vinkhuyzen AA, Dudbridge F, Middeldorp CM. Research review: Polygenic methods and their application to psychiatric traits. J Child Psychol Psychiatry. 2014;55:1068–87.
-
(2014)
J Child Psychol Psychiatry
, vol.55
, pp. 1068-1087
-
-
Wray, N.R.1
Lee, S.H.2
Mehta, D.3
Vinkhuyzen, A.A.4
Dudbridge, F.5
Middeldorp, C.M.6
-
20
-
-
84954550234
-
Meta-analysis of genome-wide association studies of anxiety disorders
-
COI: 1:STN:280:DC%2BC28novVSntQ%3D%3D
-
Otowa T, Hek K, Lee M, Byrne EM, Mirza SS, Nivard MG, et al. Meta-analysis of genome-wide association studies of anxiety disorders. Mol Psychiatry. 2016;21:1485.
-
(2016)
Mol Psychiatry
, vol.21
, pp. 1485
-
-
Otowa, T.1
Hek, K.2
Lee, M.3
Byrne, E.M.4
Mirza, S.S.5
Nivard, M.G.6
-
21
-
-
85032568947
-
Largest GWAS of PTSD (N = 20 070) yields genetic overlap with schizophrenia and sex differences in heritability
-
[Epub ahead of print]
-
Duncan LE, Ratanatharathorn A, Aiello AE, Almli LM, Amstadter AB, Ashley-Koch AE et al. Largest GWAS of PTSD (N = 20 070) yields genetic overlap with schizophrenia and sex differences in heritability. Mol Psychiatry. 2017 Apr 25. doi:10.1038/mp.2017.77. [Epub ahead of print].
-
(2017)
Mol Psychiatry
-
-
Duncan, L.E.1
Ratanatharathorn, A.2
Aiello, A.E.3
Almli, L.M.4
Amstadter, A.B.5
Ashley-Koch, A.E.6
-
22
-
-
84883465830
-
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
-
Cross-Disorder Group of the Psychiatric Genomics C, Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet. 2013;45:984–94.
-
(2013)
Nat Genet
, vol.45
, pp. 984-994
-
-
Lee, S.H.1
Ripke, S.2
Neale, B.M.3
Faraone, S.V.4
Purcell, S.M.5
-
23
-
-
85020912677
-
Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder
-
COI: 1:CAS:528:DC%2BC2sXnvVSktg%3D%3D, PID: 5545718
-
Charney AW, Ruderfer DM, Stahl EA, Moran JL, Chambert K, Belliveau RA, et al. Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder. Transl Psychiatry. 2017;7:e993.
-
(2017)
Transl Psychiatry
, vol.7
-
-
Charney, A.W.1
Ruderfer, D.M.2
Stahl, E.A.3
Moran, J.L.4
Chambert, K.5
Belliveau, R.A.6
-
24
-
-
84997770295
-
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
-
CNV Schizophrenia Working Groups of the Psychiatric Genomics Consortium. Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nat Genet. 2017;49:27–35.
-
(2017)
Nat Genet
, vol.49
, pp. 27-35
-
-
-
25
-
-
84989926166
-
Increased burden of ultra-rare protein-altering variants among 4877 individuals with schizophrenia
-
COI: 1:CAS:528:DC%2BC28Xhs1SltLrF, PID: 5104192
-
Genovese G, Fromer M, Stahl EA, Ruderfer DM, Chambert K, Landen M, et al. Increased burden of ultra-rare protein-altering variants among 4877 individuals with schizophrenia. Nat Neurosci. 2016;19:1433–41.
-
(2016)
Nat Neurosci
, vol.19
, pp. 1433-1441
-
-
Genovese, G.1
Fromer, M.2
Stahl, E.A.3
Ruderfer, D.M.4
Chambert, K.5
Landen, M.6
-
26
-
-
85015375341
-
Prevalence and architecture of de novo mutations in developmental disorders
-
Deciphering Developmental Disorders S. Prevalence and architecture of de novo mutations in developmental disorders. Nature. 2017;542:433–8.
-
(2017)
Nature
, vol.542
, pp. 433-438
-
-
-
27
-
-
85018748582
-
De novo coding variants are strongly associated with Tourette disorder
-
COI: 1:CAS:528:DC%2BC2sXntFelu74%3D, PID: 5769876, e489
-
Willsey AJ, Fernandez TV, Yu D, King RA, Dietrich A, Xing J, et al. De novo coding variants are strongly associated with Tourette disorder. Neuron. 2017;94:486–99. e489
-
(2017)
Neuron
, vol.94
, pp. 486-499
-
-
Willsey, A.J.1
Fernandez, T.V.2
Yu, D.3
King, R.A.4
Dietrich, A.5
Xing, J.6
-
28
-
-
85014572880
-
Autism genetics: opportunities and challenges for clinical translation
-
COI: 1:CAS:528:DC%2BC2sXktlKns7o%3D
-
Vorstman JA, Parr JR, Moreno-De-Luca D, Anney RJ, Nurnberger JI Jr., Hallmayer JF. Autism genetics: opportunities and challenges for clinical translation. Nat Rev Genet. 2017;18:362–76.
-
(2017)
Nat Rev Genet
, vol.18
, pp. 362-376
-
-
Vorstman, J.A.1
Parr, J.R.2
Moreno-De-Luca, D.3
Anney, R.J.4
Nurnberger, J.I.5
Hallmayer, J.F.6
-
29
-
-
84962890386
-
Advancing the understanding of autism disease mechanisms through genetics
-
PID: 5072455
-
de la Torre-Ubieta L, Won H, Stein JL, Geschwind DH. Advancing the understanding of autism disease mechanisms through genetics. Nat Med. 2016;22:345–61.
-
(2016)
Nat Med
, vol.22
, pp. 345-361
-
-
de la Torre-Ubieta, L.1
Won, H.2
Stein, J.L.3
Geschwind, D.H.4
-
30
-
-
84962233946
-
Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders
-
COI: 1:CAS:528:DC%2BC28XktFeqtLY%3D, PID: 26974950
-
Singh T, Kurki MI, Curtis D, Purcell SM, Crooks L, McRae J, et al. Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders. Nat Neurosci. 2016;19:571–7.
-
(2016)
Nat Neurosci
, vol.19
, pp. 571-577
-
-
Singh, T.1
Kurki, M.I.2
Curtis, D.3
Purcell, S.M.4
Crooks, L.5
McRae, J.6
-
31
-
-
84879419343
-
Pleiotropy in complex traits: challenges and strategies
-
COI: 1:CAS:528:DC%2BC3sXptV2qsr8%3D, PID: 23752797
-
Solovieff N, Cotsapas C, Lee PH, Purcell SM, Smoller JW. Pleiotropy in complex traits: challenges and strategies. Nat Rev Genet. 2013;14:483–95.
-
(2013)
Nat Rev Genet
, vol.14
, pp. 483-495
-
-
Solovieff, N.1
Cotsapas, C.2
Lee, P.H.3
Purcell, S.M.4
Smoller, J.W.5
-
32
-
-
84858434210
-
CNVs: harbingers of a rare variant revolution in psychiatric genetics
-
COI: 1:CAS:528:DC%2BC38Xkt1Gmsbg%3D, PID: 22424231
-
Malhotra D, Sebat J. CNVs: harbingers of a rare variant revolution in psychiatric genetics. Cell. 2012;148:1223–41.
-
(2012)
Cell
, vol.148
, pp. 1223-1241
-
-
Malhotra, D.1
Sebat, J.2
-
33
-
-
84927574047
-
Polygenic risk score and the psychosis continuum model
-
COI: 1:STN:280:DC%2BC2cfmt1OhsA%3D%3D, PID: 24961959
-
Tesli M, Espeseth T, Bettella F, Mattingsdal M, Aas M, Melle I, et al. Polygenic risk score and the psychosis continuum model. Acta Psychiatr Scand. 2014;130:311–7.
-
(2014)
Acta Psychiatr Scand
, vol.130
, pp. 311-317
-
-
Tesli, M.1
Espeseth, T.2
Bettella, F.3
Mattingsdal, M.4
Aas, M.5
Melle, I.6
-
34
-
-
84930925039
-
Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood
-
COI: 1:CAS:528:DC%2BC2MXhtVWgsLnE
-
Hatzimanolis A, Bhatnagar P, Moes A, Wang R, Roussos P, Bitsios P, et al. Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood. Am J Med Genet B Neuropsychiatr Genet. 2015;168:392–401.
-
(2015)
Am J Med Genet B Neuropsychiatr Genet
, vol.168
, pp. 392-401
-
-
Hatzimanolis, A.1
Bhatnagar, P.2
Moes, A.3
Wang, R.4
Roussos, P.5
Bitsios, P.6
-
35
-
-
84876936728
-
Polygenic risk for schizophrenia is associated with cognitive change between childhood and old age
-
McIntosh AM, Gow A, Luciano M, Davies G, Liewald DC, Harris SE, et al. Polygenic risk for schizophrenia is associated with cognitive change between childhood and old age. Biol Psychiatry. 2013;73:938–43.
-
(2013)
Biol Psychiatry
, vol.73
, pp. 938-943
-
-
McIntosh, A.M.1
Gow, A.2
Luciano, M.3
Davies, G.4
Liewald, D.C.5
Harris, S.E.6
-
36
-
-
84937509570
-
The relationship of common risk variants and polygenic risk for schizophrenia to sensorimotor gating
-
Roussos P, Giakoumaki SG, Zouraraki C, Fiullard JF, Karagiorga V-E, Tsapakis E-M, et al. The relationship of common risk variants and polygenic risk for schizophrenia to sensorimotor gating. Biol Psychiatry. 2016;79:988–96.
-
(2016)
Biol Psychiatry
, vol.79
, pp. 988-996
-
-
Roussos, P.1
Giakoumaki, S.G.2
Zouraraki, C.3
Fiullard, J.F.4
Karagiorga, V.E.5
Tsapakis, E.M.6
-
37
-
-
84930925715
-
Polygenic risk for schizophrenia associated with working memory-related prefrontal brain activation in patients with schizophrenia and healthy controls
-
Kauppi K, Westlye LT, Tesli M, Bettella F, Brandt CL, Mattingsdal M, et al. Polygenic risk for schizophrenia associated with working memory-related prefrontal brain activation in patients with schizophrenia and healthy controls. Schizophr Bull. 2015;41:736–43.
-
(2015)
Schizophr Bull
, vol.41
, pp. 736-743
-
-
Kauppi, K.1
Westlye, L.T.2
Tesli, M.3
Bettella, F.4
Brandt, C.L.5
Mattingsdal, M.6
-
38
-
-
85008262509
-
Schizophrenia risk alleles and neurodevelopmental outcomes in childhood: a population-based cohort study
-
Riglin L, Collishaw S, Richards A, Thapar AK, Maughan B, O’Donovan MC, et al. Schizophrenia risk alleles and neurodevelopmental outcomes in childhood: a population-based cohort study. Lancet Psychiatry. 2017;4:57–62.
-
(2017)
Lancet Psychiatry
, vol.4
, pp. 57-62
-
-
Riglin, L.1
Collishaw, S.2
Richards, A.3
Thapar, A.K.4
Maughan, B.5
O’Donovan, M.C.6
-
39
-
-
84876296688
-
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
-
Cross Disorder Group of the Psychiatric GWAS Consortium. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet. 2013;381:1371–9.
-
(2013)
Lancet
, vol.381
, pp. 1371-1379
-
-
-
40
-
-
85032033723
-
Genetic overlap between schizophrenia and developmental psychopathology: longitudinal and multivariate polygenic risk prediction of common psychiatric traits during development
-
PID: 28338919
-
Nivard MG, Gage SH, Hottenga JJ, van Beijsterveldt CE, Abdellaoui A, Bartels M, et al. Genetic overlap between schizophrenia and developmental psychopathology: longitudinal and multivariate polygenic risk prediction of common psychiatric traits during development. Schizophr Bull. 2017;43:1197–207.
-
(2017)
Schizophr Bull
, vol.43
, pp. 1197-1207
-
-
Nivard, M.G.1
Gage, S.H.2
Hottenga, J.J.3
van Beijsterveldt, C.E.4
Abdellaoui, A.5
Bartels, M.6
-
41
-
-
84962567847
-
Phenotypic manifestation of genetic risk for schizophrenia during adolescence in the general population
-
PID: 26818099
-
Jones HJ, Stergiakouli E, Tansey KE, Hubbard L, Heron J, Cannon M, et al. Phenotypic manifestation of genetic risk for schizophrenia during adolescence in the general population. JAMA Psychiatry. 2016;73:221–8.
-
(2016)
JAMA Psychiatry
, vol.73
, pp. 221-228
-
-
Jones, H.J.1
Stergiakouli, E.2
Tansey, K.E.3
Hubbard, L.4
Heron, J.5
Cannon, M.6
-
42
-
-
85002374791
-
Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders
-
COI: 1:CAS:528:DC%2BC28XitVSrurnJ, PID: 27918536
-
Lo MT, Hinds DA, Tung JY, Franz C, Fan CC, Wang Y, et al. Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders. Nat Genet. 2017;49:152–6.
-
(2017)
Nat Genet
, vol.49
, pp. 152-156
-
-
Lo, M.T.1
Hinds, D.A.2
Tung, J.Y.3
Franz, C.4
Fan, C.C.5
Wang, Y.6
-
43
-
-
85028296791
-
LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
-
COI: 1:CAS:528:DC%2BC1cXhvVGktb%2FM, PID: 27663502
-
Zheng J, Erzurumluoglu AM, Elsworth BL, Kemp JP, Howe L, Haycock PC, et al. LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis. Bioinformatics. 2017;33:272–9.
-
(2017)
Bioinformatics
, vol.33
, pp. 272-279
-
-
Zheng, J.1
Erzurumluoglu, A.M.2
Elsworth, B.L.3
Kemp, J.P.4
Howe, L.5
Haycock, P.C.6
-
44
-
-
84923077204
-
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
-
Network and Pathway Analysis Subgroup of Psychiatric Genomics Consortium. Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat Neurosci. 2015;18:199–209.
-
(2015)
Nat Neurosci
, vol.18
, pp. 199-209
-
-
-
45
-
-
84958074030
-
Schizophrenia risk from complex variation of complement component 4
-
COI: 1:CAS:528:DC%2BC28XhsFyitb4%3D, PID: 26814963
-
Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, et al. Schizophrenia risk from complex variation of complement component 4. Nature. 2016;530:177–83.
-
(2016)
Nature
, vol.530
, pp. 177-183
-
-
Sekar, A.1
Bialas, A.R.2
de Rivera, H.3
Davis, A.4
Hammond, T.R.5
Kamitaki, N.6
-
46
-
-
85016106888
-
Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia
-
COI: 1:STN:280:DC%2BC1cvhslaqtg%3D%3D, PID: 28348379
-
Devor A, Andreassen OA, Wang Y, Maki-Marttunen T, Smeland OB, Fan CC, et al. Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia. Mol Psychiatry. 2017;22:792–801.
-
(2017)
Mol Psychiatry
, vol.22
, pp. 792-801
-
-
Devor, A.1
Andreassen, O.A.2
Wang, Y.3
Maki-Marttunen, T.4
Smeland, O.B.5
Fan, C.C.6
-
47
-
-
84994130171
-
The road to precision psychiatry: translating genetics into disease mechanisms
-
COI: 1:CAS:528:DC%2BC28XhslGgsLfJ, PID: 27786179
-
Gandal MJ, Leppa V, Won H, Parikshak NN, Geschwind DH. The road to precision psychiatry: translating genetics into disease mechanisms. Nat Neurosci. 2016;19:1397–407.
-
(2016)
Nat Neurosci
, vol.19
, pp. 1397-1407
-
-
Gandal, M.J.1
Leppa, V.2
Won, H.3
Parikshak, N.N.4
Geschwind, D.H.5
-
48
-
-
84994079504
-
Translating genome-wide association findings into new therapeutics for psychiatry
-
COI: 1:CAS:528:DC%2BC28XhslGgsLfE, PID: 27786187
-
Breen G, Li Q, Roth BL, O’Donnell P, Didriksen M, Dolmetsch R, et al. Translating genome-wide association findings into new therapeutics for psychiatry. Nat Neurosci. 2016;19:1392–6.
-
(2016)
Nat Neurosci
, vol.19
, pp. 1392-1396
-
-
Breen, G.1
Li, Q.2
Roth, B.L.3
O’Donnell, P.4
Didriksen, M.5
Dolmetsch, R.6
-
49
-
-
84928019089
-
Developing medicines that mimic the natural successes of the human genome: lessons from NPC1L1, HMGCR, PCSK9, APOC3, and CETP
-
PID: 25881938
-
Kathiresan S. Developing medicines that mimic the natural successes of the human genome: lessons from NPC1L1, HMGCR, PCSK9, APOC3, and CETP. J Am Coll Cardiol. 2015;65:1562–6.
-
(2015)
J Am Coll Cardiol
, vol.65
, pp. 1562-1566
-
-
Kathiresan, S.1
-
50
-
-
84873913724
-
Is there a general factor of prevalent psychopathology during adulthood?
-
PID: 22845652
-
Lahey BB, Applegate B, Hakes JK, Zald DH, Hariri AR, Rathouz PJ. Is there a general factor of prevalent psychopathology during adulthood? J Abnorm Psychol. 2012;121:971–7.
-
(2012)
J Abnorm Psychol
, vol.121
, pp. 971-977
-
-
Lahey, B.B.1
Applegate, B.2
Hakes, J.K.3
Zald, D.H.4
Hariri, A.R.5
Rathouz, P.J.6
-
51
-
-
84887022573
-
ADHD, autism spectrum disorder, temperament, and character: phenotypical associations and etiology in a Swedish childhood twin study
-
PID: 23790516
-
Kerekes N, Brandstrom S, Lundstrom S, Rastam M, Nilsson T, Anckarsater H. ADHD, autism spectrum disorder, temperament, and character: phenotypical associations and etiology in a Swedish childhood twin study. Compr Psychiatry. 2013;54:1140–7.
-
(2013)
Compr Psychiatry
, vol.54
, pp. 1140-1147
-
-
Kerekes, N.1
Brandstrom, S.2
Lundstrom, S.3
Rastam, M.4
Nilsson, T.5
Anckarsater, H.6
-
52
-
-
70450223891
-
Common disorders are quantitative traits
-
COI: 1:CAS:528:DC%2BD1MXhsVaksL%2FL, PID: 19859063
-
Plomin R, Haworth CM, Davis OS. Common disorders are quantitative traits. Nat Rev Genet. 2009;10:872–8.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 872-878
-
-
Plomin, R.1
Haworth, C.M.2
Davis, O.S.3
-
53
-
-
82955203855
-
Childhood attention-deficit hyperactivity disorder as an extreme of a continuous trait: a quantitative genetic study of 8500 twin pairs
-
PID: 21923806
-
Larsson H, Anckarsater H, Rastam M, Chang Z, Lichtenstein P. Childhood attention-deficit hyperactivity disorder as an extreme of a continuous trait: a quantitative genetic study of 8500 twin pairs. J Child Psychol Psychiatry. 2012;53:73–80.
-
(2012)
J Child Psychol Psychiatry
, vol.53
, pp. 73-80
-
-
Larsson, H.1
Anckarsater, H.2
Rastam, M.3
Chang, Z.4
Lichtenstein, P.5
-
54
-
-
84958882630
-
Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population
-
PID: 25754080
-
Clarke TK, Lupton MK, Fernandez-Pujals AM, Starr J, Davies G, Cox S, et al. Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population. Mol Psychiatry. 2016;21:419–25.
-
(2016)
Mol Psychiatry
, vol.21
, pp. 419-425
-
-
Clarke, T.K.1
Lupton, M.K.2
Fernandez-Pujals, A.M.3
Starr, J.4
Davies, G.5
Cox, S.6
-
55
-
-
84907538769
-
Attention-deficit/hyperactivity disorder polygenic risk scores predict attention problems in a population-based sample of children
-
PID: 25245356, e1126
-
Groen-Blokhuis MM, Middeldorp CM, Kan KJ, Abdellaoui A, van Beijsterveldt CE, Ehli EA, et al. Attention-deficit/hyperactivity disorder polygenic risk scores predict attention problems in a population-based sample of children. J Am Acad Child Adolesc Psychiatry. 2014;53:1123–9. e1126
-
(2014)
J Am Acad Child Adolesc Psychiatry
, vol.53
, pp. 1123-1129
-
-
Groen-Blokhuis, M.M.1
Middeldorp, C.M.2
Kan, K.J.3
Abdellaoui, A.4
van Beijsterveldt, C.E.5
Ehli, E.A.6
-
56
-
-
84961392741
-
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population
-
COI: 1:CAS:528:DC%2BC28XksVyrsL0%3D, PID: 26998691
-
Robinson EB, St Pourcain B, Anttila V, Kosmicki JA, Bulik-Sullivan B, Grove J, et al. Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population. Nat Genet. 2016;48:552–5.
-
(2016)
Nat Genet
, vol.48
, pp. 552-555
-
-
Robinson, E.B.1
St Pourcain, B.2
Anttila, V.3
Kosmicki, J.A.4
Bulik-Sullivan, B.5
Grove, J.6
-
57
-
-
85029384750
-
Association between polygenic risk for schizophrenia, neurocognition and social cognition across development
-
COI: 1:STN:280:DC%2BC2srhsl2ksg%3D%3D, PID: 27754483
-
Germine L, Robinson EB, Smoller JW, Calkins ME, Moore TM, Hakonarson H, et al. Association between polygenic risk for schizophrenia, neurocognition and social cognition across development. Transl Psychiatry. 2016;6:e924.
-
(2016)
Transl Psychiatry
, vol.6
-
-
Germine, L.1
Robinson, E.B.2
Smoller, J.W.3
Calkins, M.E.4
Moore, T.M.5
Hakonarson, H.6
-
58
-
-
77954230363
-
Research domain criteria (RDoC): toward a new classification framework for research on mental disorders
-
PID: 20595427
-
Insel T, Cuthbert B, Garvey M, Heinssen R, Pine DS, Quinn K, et al. Research domain criteria (RDoC): toward a new classification framework for research on mental disorders. Am J Psychiatry. 2010;167:748–51.
-
(2010)
Am J Psychiatry
, vol.167
, pp. 748-751
-
-
Insel, T.1
Cuthbert, B.2
Garvey, M.3
Heinssen, R.4
Pine, D.S.5
Quinn, K.6
-
60
-
-
77952909945
-
The diagnosis of mental disorders: the problem of reification
-
Hyman SE. The diagnosis of mental disorders: the problem of reification. Annu Rev Clin Psychol. 2010;6:12.11–25.
-
(2010)
Annu Rev Clin Psychol
, vol.6
, pp. 12.11-25
-
-
Hyman, S.E.1
-
61
-
-
84855359174
-
Levels of explanation in psychiatric and substance use disorders: implications for the development of an etiologically based nosology
-
COI: 1:STN:280:DC%2BC387hsVGisw%3D%3D, PID: 21670729
-
Kendler KS. Levels of explanation in psychiatric and substance use disorders: implications for the development of an etiologically based nosology. Mol Psychiatry. 2012;17:11–21.
-
(2012)
Mol Psychiatry
, vol.17
, pp. 11-21
-
-
Kendler, K.S.1
-
62
-
-
85028720725
-
Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa
-
PID: 28494655
-
Duncan L, Yilmaz Z, Gaspar H, Walters R, Goldstein J, Anttila V, et al. Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa. Am J Psychiatry. 2017;174:850–8.
-
(2017)
Am J Psychiatry
, vol.174
, pp. 850-858
-
-
Duncan, L.1
Yilmaz, Z.2
Gaspar, H.3
Walters, R.4
Goldstein, J.5
Anttila, V.6
-
63
-
-
0014702024
-
Establishment of diagnostic validity in psychiatric illness: its application to schizophrenia
-
COI: 1:STN:280:DyaE3c%2FlvFyitw%3D%3D, PID: 5409569
-
Robins E, Guze S. Establishment of diagnostic validity in psychiatric illness: its application to schizophrenia. Am J Psychiatry. 1970;126:983–7.
-
(1970)
Am J Psychiatry
, vol.126
, pp. 983-987
-
-
Robins, E.1
Guze, S.2
-
64
-
-
0025185751
-
Toward a scientific psychiatric nosology. Strengths and limitations
-
COI: 1:STN:280:DyaK3M%2FisVGjsA%3D%3D, PID: 2222134
-
Kendler KS. Toward a scientific psychiatric nosology. Strengths and limitations. Arch Gen Psychiatry. 1990;47:969–73.
-
(1990)
Arch Gen Psychiatry
, vol.47
, pp. 969-973
-
-
Kendler, K.S.1
-
65
-
-
0027745252
-
Identification of the phenotype in psychiatric genetics
-
COI: 1:STN:280:DyaK2c7mt1eisw%3D%3D, PID: 8117756
-
Tsuang M, Faraone S, Lyons M. Identification of the phenotype in psychiatric genetics. Eur Arch Psychiatry Clin Neurosci. 1993;243:131–42.
-
(1993)
Eur Arch Psychiatry Clin Neurosci
, vol.243
, pp. 131-142
-
-
Tsuang, M.1
Faraone, S.2
Lyons, M.3
-
66
-
-
85047697427
-
Reflections on the relationship between psychiatric genetics and psychiatric nosology
-
PID: 16816216
-
Kendler KS. Reflections on the relationship between psychiatric genetics and psychiatric nosology. Am J Psychiatry. 2006;163:1138–46.
-
(2006)
Am J Psychiatry
, vol.163
, pp. 1138-1146
-
-
Kendler, K.S.1
-
67
-
-
70449657826
-
An historical framework for psychiatric nosology
-
PID: 19368761
-
Kendler KS. An historical framework for psychiatric nosology. Psychol Med. 2009;39:1935–41.
-
(2009)
Psychol Med
, vol.39
, pp. 1935-1941
-
-
Kendler, K.S.1
-
68
-
-
84867002677
-
Biomarkers and attention-deficit/hyperactivity disorder: a systematic review and meta-analyses
-
PID: 23021477, e1020
-
Scassellati C, Bonvicini C, Faraone SV, Gennarelli M. Biomarkers and attention-deficit/hyperactivity disorder: a systematic review and meta-analyses. J Am Acad Child Adolesc Psychiatry. 2012;51:1003–19. e1020
-
(2012)
J Am Acad Child Adolesc Psychiatry
, vol.51
, pp. 1003-1019
-
-
Scassellati, C.1
Bonvicini, C.2
Faraone, S.V.3
Gennarelli, M.4
-
69
-
-
84912141486
-
Regularized machine learning in the genetic prediction of complex traits
-
PID: 25393026
-
Okser S, Pahikkala T, Airola A, Salakoski T, Ripatti S, Aittokallio T. Regularized machine learning in the genetic prediction of complex traits. PLoS Genet. 2014;10:e1004754.
-
(2014)
PLoS Genet
, vol.10
-
-
Okser, S.1
Pahikkala, T.2
Airola, A.3
Salakoski, T.4
Ripatti, S.5
Aittokallio, T.6
-
70
-
-
84879324656
-
Pitfalls of predicting complex traits from SNPs
-
COI: 1:CAS:528:DC%2BC3sXpsV2mu70%3D, PID: 23774735
-
Wray NR, Yang J, Hayes BJ, Price AL, Goddard ME, Visscher PM. Pitfalls of predicting complex traits from SNPs. Nat Rev Genet. 2013;14:507–15.
-
(2013)
Nat Rev Genet
, vol.14
, pp. 507-515
-
-
Wray, N.R.1
Yang, J.2
Hayes, B.J.3
Price, A.L.4
Goddard, M.E.5
Visscher, P.M.6
-
71
-
-
84922544557
-
Genetic studies of major depressive disorder: why are there no genome-wide association study findings and what can we do about it?
-
PID: 25201436
-
Levinson DF, Mostafavi S, Milaneschi Y, Rivera M, Ripke S, Wray NR, et al. Genetic studies of major depressive disorder: why are there no genome-wide association study findings and what can we do about it? Biol Psychiatry. 2014;76:510–2.
-
(2014)
Biol Psychiatry
, vol.76
, pp. 510-512
-
-
Levinson, D.F.1
Mostafavi, S.2
Milaneschi, Y.3
Rivera, M.4
Ripke, S.5
Wray, N.R.6
-
72
-
-
84962499225
-
Estimating effect sizes and expected replication probabilities from GWAS summary statistics
-
PID: 26909100
-
Holland D, Wang Y, Thompson WK, Schork A, Chen CH, Lo MT, et al. Estimating effect sizes and expected replication probabilities from GWAS summary statistics. Front Genet. 2016;7:15.
-
(2016)
Front Genet
, vol.7
, pp. 15
-
-
Holland, D.1
Wang, Y.2
Thompson, W.K.3
Schork, A.4
Chen, C.H.5
Lo, M.T.6
-
73
-
-
84893378179
-
Searching for missing heritability: designing rare variant association studies
-
COI: 1:CAS:528:DC%2BC2cXhs1Sntbs%3D, PID: 24443550
-
Zuk O, Schaffner SF, Samocha K, Do R, Hechter E, Kathiresan S, et al. Searching for missing heritability: designing rare variant association studies. Proc Natl Acad Sci USA. 2014;111:E455–464.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. E455-E464
-
-
Zuk, O.1
Schaffner, S.F.2
Samocha, K.3
Do, R.4
Hechter, E.5
Kathiresan, S.6
-
74
-
-
85000613803
-
The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease
-
PID: 25906071
-
Moutsianas L, Agarwala V, Fuchsberger C, Flannick J, Rivas MA, Gaulton KJ, et al. The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease. PLoS Genet. 2015;11:e1005165.
-
(2015)
PLoS Genet
, vol.11
-
-
Moutsianas, L.1
Agarwala, V.2
Fuchsberger, C.3
Flannick, J.4
Rivas, M.A.5
Gaulton, K.J.6
-
75
-
-
85020932930
-
-
BiorXiv
-
Sullivan PF, Agrawal A, Bulik CM, Andreassen OA, Borglum A, Breen G et al. Psychiatric genomics: an update and an agenda. BiorXiv. 2017. 10.1101/115600.
-
(2017)
Psychiatric Genomics: An Update and An Agenda
-
-
Sullivan, P.F.1
Agrawal, A.2
Bulik, C.M.3
Andreassen, O.A.4
Borglum, A.5
Breen, G.6
-
76
-
-
85020941675
-
An expanded view of complex traits: from polygenic to omnigenic
-
COI: 1:CAS:528:DC%2BC2sXhtVWrtrjM, PID: 28622505
-
Boyle EA, Li YI, Pritchard JK. An expanded view of complex traits: from polygenic to omnigenic. Cell. 2017;169:1177–86.
-
(2017)
Cell
, vol.169
, pp. 1177-1186
-
-
Boyle, E.A.1
Li, Y.I.2
Pritchard, J.K.3
-
77
-
-
85049284114
-
Analysis of shared heritability in common disorders of the brain
-
Anttila V, Bulik-Sullivan B, Finucane H, Bras J, Duncan L, Escott-Price V et al. Analysis of shared heritability in common disorders of the brain. BioRXiv. 2017. 10.1101/048991.
-
(2017)
Biorxiv
-
-
Anttila, V.1
Bulik-Sullivan, B.2
Finucane, H.3
Bras, J.4
Duncan, L.5
Escott-Price, V.6
-
78
-
-
85019705612
-
The use of electronic health records for psychiatric phenotyping and genomics
-
[Epub ahead of print]
-
Smoller JW. The use of electronic health records for psychiatric phenotyping and genomics. Am J Med Genet B Neuropsychiatr Genet. 2017 May 30. doi:10.1002/ajmg.b.32548. [Epub ahead of print].
-
(2017)
Am J Med Genet B Neuropsychiatr Genet
-
-
Smoller, J.W.1
-
79
-
-
84926430250
-
UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age
-
PID: 25826379
-
Sudlow C, Gallacher J, Allen N, Beral V, Burton P, Danesh J, et al. UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age. PLoS Med. 2015;12:e1001779.
-
(2015)
PLoS Med
, vol.12
-
-
Sudlow, C.1
Gallacher, J.2
Allen, N.3
Beral, V.4
Burton, P.5
Danesh, J.6
-
81
-
-
84958659058
-
Unravelling the human genome-phenome relationship using phenome-wide association studies
-
COI: 1:CAS:528:DC%2BC28XisFGqt74%3D
-
Bush WS, Oetjens MT, Crawford DC. Unravelling the human genome-phenome relationship using phenome-wide association studies. Nat Rev Genet. 2016;17:129–45.
-
(2016)
Nat Rev Genet
, vol.17
, pp. 129-145
-
-
Bush, W.S.1
Oetjens, M.T.2
Crawford, D.C.3
-
82
-
-
85011360845
-
Association of Genetic Risk Variants With Attention-Deficit/Hyperactivity Disorder Trajectories in the General Population
-
Riglin L, Collishaw S, Thapar AK, Dalsgaard S, Langley K, Smith GD, et al. Association of Genetic Risk Variants With Attention-Deficit/Hyperactivity Disorder Trajectories in the General Population. JAMA Psychiatry. 2016;73:1285–92.
-
(2016)
JAMA Psychiatry
, vol.73
, pp. 1285-1292
-
-
Riglin, L.1
Collishaw, S.2
Thapar, A.K.3
Dalsgaard, S.4
Langley, K.5
Smith, G.D.6
-
83
-
-
84881193129
-
Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network
-
COI: 1:CAS:528:DC%2BC3sXht1WqsrjM, PID: 3894107
-
Gulsuner S, Walsh T, Watts AC, Lee MK, Thornton AM, Casadei S, et al. Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network. Cell. 2013;154:518–29.
-
(2013)
Cell
, vol.154
, pp. 518-529
-
-
Gulsuner, S.1
Walsh, T.2
Watts, A.C.3
Lee, M.K.4
Thornton, A.M.5
Casadei, S.6
-
84
-
-
84889583293
-
Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism
-
COI: 1:CAS:528:DC%2BC3sXhvFWis7zP, PID: 3995413
-
Willsey AJ, Sanders SJ, Li M, Dong S, Tebbenkamp AT, Muhle RA, et al. Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism. Cell. 2013;155:997–1007.
-
(2013)
Cell
, vol.155
, pp. 997-1007
-
-
Willsey, A.J.1
Sanders, S.J.2
Li, M.3
Dong, S.4
Tebbenkamp, A.T.5
Muhle, R.A.6
-
85
-
-
84930823499
-
The Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort as a resource for studying psychopathology in childhood and adolescence: a summary of findings for depression and psychosis
-
Niarchou M, Zammit S, Lewis G. The Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort as a resource for studying psychopathology in childhood and adolescence: a summary of findings for depression and psychosis. Soc Psychiatry Psychiatr Epidemiol. 2015;50:1017–27.
-
(2015)
Soc Psychiatry Psychiatr Epidemiol
, vol.50
, pp. 1017-1027
-
-
Niarchou, M.1
Zammit, S.2
Lewis, G.3
-
87
-
-
84991034754
-
Partitioning heritability analysis reveals a shared genetic basis of brain anatomy and schizophrenia
-
COI: 1:CAS:528:DC%2BC28Xhs1Ogs7%2FI, PID: 5144575
-
Lee PH, Baker JT, Holmes AJ, Jahanshad N, Ge T, Jung JY, et al. Partitioning heritability analysis reveals a shared genetic basis of brain anatomy and schizophrenia. Mol Psychiatry. 2016;21:1680–9.
-
(2016)
Mol Psychiatry
, vol.21
, pp. 1680-1689
-
-
Lee, P.H.1
Baker, J.T.2
Holmes, A.J.3
Jahanshad, N.4
Ge, T.5
Jung, J.Y.6
-
88
-
-
85018597877
-
Emerging global initiatives in neurogenetics: the enhancing neuroimaging genetics through meta-analysis (ENIGMA) consortium
-
COI: 1:CAS:528:DC%2BC2sXmsVWgsLc%3D, PID: 5918136
-
Bearden CE, Thompson PM. Emerging global initiatives in neurogenetics: the enhancing neuroimaging genetics through meta-analysis (ENIGMA) consortium. Neuron. 2017;94:232–6.
-
(2017)
Neuron
, vol.94
, pp. 232-236
-
-
Bearden, C.E.1
Thompson, P.M.2
-
89
-
-
84930361535
-
Research domain criteria: toward future psychiatric nosologies
-
PID: 25987867
-
Cuthbert BN. Research domain criteria: toward future psychiatric nosologies. Dialogues Clin Neurosci. 2015;17:89–97.
-
(2015)
Dialogues Clin Neurosci
, vol.17
, pp. 89-97
-
-
Cuthbert, B.N.1
-
90
-
-
84940648792
-
Mendelian randomization: new applications in the coming age of hypothesis-free causality
-
COI: 1:CAS:528:DC%2BC2MXhsFShs7jN
-
Evans DM, Davey Smith G. Mendelian randomization: new applications in the coming age of hypothesis-free causality. Annu Rev Genom Hum Genet. 2015;16:327–50.
-
(2015)
Annu Rev Genom Hum Genet
, vol.16
, pp. 327-350
-
-
Evans, D.M.1
Davey Smith, G.2
-
91
-
-
85014708940
-
Genetic association of waist-to-hip ratio with cardiometabolic traits, type 2 diabetes, and coronary heart disease
-
PID: 5571980
-
Emdin CA, Khera AV, Natarajan P, Klarin D, Zekavat SM, Hsiao AJ, et al. Genetic association of waist-to-hip ratio with cardiometabolic traits, type 2 diabetes, and coronary heart disease. JAMA. 2017;317:626–34.
-
(2017)
JAMA
, vol.317
, pp. 626-634
-
-
Emdin, C.A.1
Khera, A.V.2
Natarajan, P.3
Klarin, D.4
Zekavat, S.M.5
Hsiao, A.J.6
-
92
-
-
84864845456
-
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
-
COI: 1:CAS:528:DC%2BC38Xnt1Cmsrc%3D, PID: 3419820
-
Voight BF, Peloso GM, Orho-Melander M, Frikke-Schmidt R, Barbalic M, Jensen MK, et al. Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet. 2012;380:572–80.
-
(2012)
Lancet
, vol.380
, pp. 572-580
-
-
Voight, B.F.1
Peloso, G.M.2
Orho-Melander, M.3
Frikke-Schmidt, R.4
Barbalic, M.5
Jensen, M.K.6
-
93
-
-
85010886820
-
Cannabis use and risk of schizophrenia: a Mendelian randomization study
-
[Epub ahead of print]
-
Vaucher J, Keating BJ, Lasserre AM, Gan W, Lyall DM, Ward J et al. Cannabis use and risk of schizophrenia: a Mendelian randomization study. Mol Psychiatry. 2017 Jan 24. doi:10.1038/mp.2016.252. [Epub ahead of print].
-
(2017)
Mol Psychiatry
-
-
Vaucher, J.1
Keating, B.J.2
Lasserre, A.M.3
Gan, W.4
Lyall, D.M.5
Ward, J.6
-
94
-
-
84968649781
-
Detection and interpretation of shared genetic influences on 42 human traits
-
COI: 1:CAS:528:DC%2BC28XnvFOmuro%3D, PID: 5207801
-
Pickrell JK, Berisa T, Liu JZ, Segurel L, Tung JY, Hinds DA. Detection and interpretation of shared genetic influences on 42 human traits. Nat Genet. 2016;48:709–17.
-
(2016)
Nat Genet
, vol.48
, pp. 709-717
-
-
Pickrell, J.K.1
Berisa, T.2
Liu, J.Z.3
Segurel, L.4
Tung, J.Y.5
Hinds, D.A.6
-
95
-
-
84877264570
-
Clinical genetics evaluation in identifying the etiology of autism spectrum disorders: 2013 guideline revisions
-
COI: 1:CAS:528:DC%2BC3sXnt12ktrc%3D
-
Schaefer GB, Mendelsohn NJ, Professional P, Guidelines C. Clinical genetics evaluation in identifying the etiology of autism spectrum disorders: 2013 guideline revisions. Genet Med. 2013;15:399–407.
-
(2013)
Genet Med
, vol.15
, pp. 399-407
-
-
Schaefer, G.B.1
Mendelsohn, N.J.2
Professional, P.3
Guidelines, C.4
-
96
-
-
84922394049
-
A framework for the interpretation of de novo mutation in human disease
-
COI: 1:CAS:528:DC%2BC2cXht1Gqtr%2FK, PID: 4222185
-
Samocha KE, Robinson EB, Sanders SJ, Stevens C, Sabo A, McGrath LM, et al. A framework for the interpretation of de novo mutation in human disease. Nat Genet. 2014;46:944–50.
-
(2014)
Nat Genet
, vol.46
, pp. 944-950
-
-
Samocha, K.E.1
Robinson, E.B.2
Sanders, S.J.3
Stevens, C.4
Sabo, A.5
McGrath, L.M.6
-
97
-
-
84908030450
-
Autism spectrum disorder severity reflects the average contribution of de novo and familial influences
-
COI: 1:CAS:528:DC%2BC2cXhs1yhtLbF
-
Robinson EB, Samocha KE, Kosmicki JA, McGrath L, Neale BM, Perlis RH, et al. Autism spectrum disorder severity reflects the average contribution of de novo and familial influences. Proc Natl Acad Sci USA. 2014;111:15161–5.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 15161-15165
-
-
Robinson, E.B.1
Samocha, K.E.2
Kosmicki, J.A.3
McGrath, L.4
Neale, B.M.5
Perlis, R.H.6
-
98
-
-
84901633682
-
One gene, many neuropsychiatric disorders: lessons from Mendelian diseases
-
COI: 1:CAS:528:DC%2BC2cXos1eqsb8%3D
-
Zhu X, Need AC, Petrovski S, Goldstein DB. One gene, many neuropsychiatric disorders: lessons from Mendelian diseases. Nat Neurosci. 2014;17:773–81.
-
(2014)
Nat Neurosci
, vol.17
, pp. 773-781
-
-
Zhu, X.1
Need, A.C.2
Petrovski, S.3
Goldstein, D.B.4
-
99
-
-
78349293844
-
The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood
-
Lichtenstein P, Carlstrom E, Rastam M, Gillberg C, Anckarsater H. The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood. Am J Psychiatry. 2010;167:1357–63.
-
(2010)
Am J Psychiatry
, vol.167
, pp. 1357-1363
-
-
Lichtenstein, P.1
Carlstrom, E.2
Rastam, M.3
Gillberg, C.4
Anckarsater, H.5
-
100
-
-
84933279742
-
Meta-analysis of the heritability of human traits based on fifty years of twin studies
-
COI: 1:CAS:528:DC%2BC2MXhtFemt7jN
-
Polderman TJ, Benyamin B, de Leeuw CA, Sullivan PF, van Bochoven A, Visscher PM, et al. Meta-analysis of the heritability of human traits based on fifty years of twin studies. Nat Genet. 2015;47:702–9.
-
(2015)
Nat Genet
, vol.47
, pp. 702-709
-
-
Polderman, T.J.1
Benyamin, B.2
de Leeuw, C.A.3
Sullivan, P.F.4
van Bochoven, A.5
Visscher, P.M.6
-
101
-
-
84924260749
-
Bipolar disorder and its relation to major psychiatric disorders: a family-based study in the Swedish population
-
Song J, Bergen SE, Kuja-Halkola R, Larsson H, Landen M, Lichtenstein P. Bipolar disorder and its relation to major psychiatric disorders: a family-based study in the Swedish population. Bipolar Disord. 2015;17:184–93.
-
(2015)
Bipolar Disord
, vol.17
, pp. 184-193
-
-
Song, J.1
Bergen, S.E.2
Kuja-Halkola, R.3
Larsson, H.4
Landen, M.5
Lichtenstein, P.6
-
102
-
-
0036212511
-
A twin study of genetic relationships between psychotic symptoms
-
Cardno AG, Rijsdijk FV, Sham PC, Murray RM, McGuffin P. A twin study of genetic relationships between psychotic symptoms. Am J Psychiatry. 2002;159:539–45.
-
(2002)
Am J Psychiatry
, vol.159
, pp. 539-545
-
-
Cardno, A.G.1
Rijsdijk, F.V.2
Sham, P.C.3
Murray, R.M.4
McGuffin, P.5
-
103
-
-
0037629099
-
The heritability of bipolar affective disorder and the genetic relationship to unipolar depression
-
McGuffin P, Rijsdijk F, Andrew M, Sham P, Katz R, Cardno A. The heritability of bipolar affective disorder and the genetic relationship to unipolar depression. Arch Gen Psychiatry. 2003;60:497–502.
-
(2003)
Arch Gen Psychiatry
, vol.60
, pp. 497-502
-
-
McGuffin, P.1
Rijsdijk, F.2
Andrew, M.3
Sham, P.4
Katz, R.5
Cardno, A.6
-
104
-
-
71349083436
-
Understanding the relation between anorexia nervosa and bulimia nervosa in a Swedish national twin sample
-
PID: 2851013
-
Bulik CM, Thornton LM, Root TL, Pisetsky EM, Lichtenstein P, Pedersen NL. Understanding the relation between anorexia nervosa and bulimia nervosa in a Swedish national twin sample. Biol Psychiatry. 2010;67:71–77.
-
(2010)
Biol Psychiatry
, vol.67
, pp. 71-77
-
-
Bulik, C.M.1
Thornton, L.M.2
Root, T.L.3
Pisetsky, E.M.4
Lichtenstein, P.5
Pedersen, N.L.6
-
105
-
-
78650169701
-
Familiality of Tourette syndrome, obsessive-compulsive disorder, and attention-deficit/hyperactivity disorder: heritability analysis in a large sib-pair sample
-
Mathews CA, Grados MA. Familiality of Tourette syndrome, obsessive-compulsive disorder, and attention-deficit/hyperactivity disorder: heritability analysis in a large sib-pair sample. J Am Acad Child Adolesc Psychiatry. 2011;50:46–54.
-
(2011)
J Am Acad Child Adolesc Psychiatry
, vol.50
, pp. 46-54
-
-
Mathews, C.A.1
Grados, M.A.2
-
106
-
-
84942509440
-
Etiological overlap between obsessive-compulsive disorder and anorexia nervosa: a longitudinal cohort, multigenerational family and twin study
-
PID: 4592656
-
Cederlof M, Thornton LM, Baker J, Lichtenstein P, Larsson H, Ruck C, et al. Etiological overlap between obsessive-compulsive disorder and anorexia nervosa: a longitudinal cohort, multigenerational family and twin study. World Psychiatry. 2015;14:333–8.
-
(2015)
World Psychiatry
, vol.14
, pp. 333-338
-
-
Cederlof, M.1
Thornton, L.M.2
Baker, J.3
Lichtenstein, P.4
Larsson, H.5
Ruck, C.6
-
107
-
-
84952908413
-
Heritability of autism spectrum disorders: a meta-analysis of twin studies
-
Tick B, Bolton P, Happe F, Rutter M, Rijsdijk F. Heritability of autism spectrum disorders: a meta-analysis of twin studies. J Child Psychol Psychiatry. 2016;57:585–95.
-
(2016)
J Child Psychol Psychiatry
, vol.57
, pp. 585-595
-
-
Tick, B.1
Bolton, P.2
Happe, F.3
Rutter, M.4
Rijsdijk, F.5
-
108
-
-
84857947079
-
Common heritable contributions to low-risk trauma, high-risk trauma, posttraumatic stress disorder, and major depression
-
Sartor CE, Grant JD, Lynskey MT, McCutcheon VV, Waldron M, Statham DJ, et al. Common heritable contributions to low-risk trauma, high-risk trauma, posttraumatic stress disorder, and major depression. Arch General Psychiatry. 2012;69:293–9.
-
(2012)
Arch General Psychiatry
, vol.69
, pp. 293-299
-
-
Sartor, C.E.1
Grant, J.D.2
Lynskey, M.T.3
McCutcheon, V.V.4
Waldron, M.5
Statham, D.J.6
-
109
-
-
0036789213
-
Genetic and environmental influences on trauma exposure and posttraumatic stress disorder symptoms: a twin study
-
Stein MB, Jang KL, Taylor S, Vernon PA, Livesley WJ. Genetic and environmental influences on trauma exposure and posttraumatic stress disorder symptoms: a twin study. Am J Psychiatry. 2002;159:1675–81.
-
(2002)
Am J Psychiatry
, vol.159
, pp. 1675-1681
-
-
Stein, M.B.1
Jang, K.L.2
Taylor, S.3
Vernon, P.A.4
Livesley, W.J.5
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