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Volumn 79, Issue 12, 2016, Pages 988-996

The Relationship of Common Risk Variants and Polygenic Risk for Schizophrenia to Sensorimotor Gating

Author keywords

Baseline startle; Endophenotypes; eQTL; GWAS; Heritability; Prepulse inhibition

Indexed keywords

NERVE GROWTH FACTOR;

EID: 84937509570     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2015.06.019     Document Type: Article
Times cited : (37)

References (59)
  • 1
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • 1 International Schizophrenia Consortium, Purcell, S.M., Wray, N.R., Stone, J.L., Visscher, P.M., O'Donovan, M.C., et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460 (2009), 748–752.
    • (2009) Nature , vol.460 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3    Visscher, P.M.4    O'Donovan, M.C.5
  • 2
    • 84885020424 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies 13 new risk loci for schizophrenia
    • 2 Ripke, S., O'Dushlaine, C., Chambert, K., Moran, J.L., Kahler, A.K., Akterin, S., et al. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet 45 (2013), 1150–1159.
    • (2013) Nat Genet , vol.45 , pp. 1150-1159
    • Ripke, S.1    O'Dushlaine, C.2    Chambert, K.3    Moran, J.L.4    Kahler, A.K.5    Akterin, S.6
  • 3
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophrenia-associated genetic loci
    • 3 Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophrenia-associated genetic loci. Nature 511 (2014), 421–427.
    • (2014) Nature , vol.511 , pp. 421-427
  • 4
    • 33845870142 scopus 로고    scopus 로고
    • Neurophysiological endophenotypes of schizophrenia: The viability of selected candidate measures
    • 4 Turetsky, B.I., Calkins, M.E., Light, G.A., Olincy, A., Radant, A.D., Swerdlow, N.R., Neurophysiological endophenotypes of schizophrenia: The viability of selected candidate measures. Schizophr Bull 33 (2007), 69–94.
    • (2007) Schizophr Bull , vol.33 , pp. 69-94
    • Turetsky, B.I.1    Calkins, M.E.2    Light, G.A.3    Olincy, A.4    Radant, A.D.5    Swerdlow, N.R.6
  • 5
    • 0018120068 scopus 로고
    • Prestimulus effects on human startle reflex in normals and schizophrenics
    • 5 Braff, D., Stone, C., Callaway, E., Geyer, M., Glick, I., Bali, L., Prestimulus effects on human startle reflex in normals and schizophrenics. Psychophysiology 15 (1978), 339–343.
    • (1978) Psychophysiology , vol.15 , pp. 339-343
    • Braff, D.1    Stone, C.2    Callaway, E.3    Geyer, M.4    Glick, I.5    Bali, L.6
  • 6
    • 35948991435 scopus 로고    scopus 로고
    • Initial heritability analyses of endophenotypic measures for schizophrenia: The consortium on the genetics of schizophrenia
    • 6 Greenwood, T.A., Braff, D.L., Light, G.A., Cadenhead, K.S., Calkins, M.E., Dobie, D.J., et al. Initial heritability analyses of endophenotypic measures for schizophrenia: The consortium on the genetics of schizophrenia. Arch Gen Psychiatry 64 (2007), 1242–1250.
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 1242-1250
    • Greenwood, T.A.1    Braff, D.L.2    Light, G.A.3    Cadenhead, K.S.4    Calkins, M.E.5    Dobie, D.J.6
  • 7
    • 0344420114 scopus 로고    scopus 로고
    • Genetic influences on prepulse inhibition of startle reflex in humans
    • 7 Anokhin, A.P., Heath, A.C., Myers, E., Ralano, A., Wood, S., Genetic influences on prepulse inhibition of startle reflex in humans. Neurosci Lett 353 (2003), 45–48.
    • (2003) Neurosci Lett , vol.353 , pp. 45-48
    • Anokhin, A.P.1    Heath, A.C.2    Myers, E.3    Ralano, A.4    Wood, S.5
  • 8
    • 45449116690 scopus 로고    scopus 로고
    • Finding suitable phenotypes for genetic studies of schizophrenia: Heritability and segregation analysis
    • 8 Aukes, M.F., Alizadeh, B.Z., Sitskoorn, M.M., Selten, J.P., Sinke, R.J., Kemner, C., et al. Finding suitable phenotypes for genetic studies of schizophrenia: Heritability and segregation analysis. Biol Psychiatry 64 (2008), 128–136.
    • (2008) Biol Psychiatry , vol.64 , pp. 128-136
    • Aukes, M.F.1    Alizadeh, B.Z.2    Sitskoorn, M.M.3    Selten, J.P.4    Sinke, R.J.5    Kemner, C.6
  • 9
    • 0033806859 scopus 로고    scopus 로고
    • Modulation of the startle response and startle laterality in relatives of schizophrenic patients and in subjects with schizotypal personality disorder: Evidence of inhibitory deficits
    • 9 Cadenhead, K.S., Swerdlow, N.R., Shafer, K.M., Diaz, M., Braff, D.L., Modulation of the startle response and startle laterality in relatives of schizophrenic patients and in subjects with schizotypal personality disorder: Evidence of inhibitory deficits. Am J Psychiatry 157 (2000), 1660–1668.
    • (2000) Am J Psychiatry , vol.157 , pp. 1660-1668
    • Cadenhead, K.S.1    Swerdlow, N.R.2    Shafer, K.M.3    Diaz, M.4    Braff, D.L.5
  • 10
    • 33644876567 scopus 로고    scopus 로고
    • Reduced prepulse inhibition in unaffected siblings of schizophrenia patients
    • 10 Kumari, V., Das, M., Zachariah, E., Ettinger, U., Sharma, T., Reduced prepulse inhibition in unaffected siblings of schizophrenia patients. Psychophysiology 42 (2005), 588–594.
    • (2005) Psychophysiology , vol.42 , pp. 588-594
    • Kumari, V.1    Das, M.2    Zachariah, E.3    Ettinger, U.4    Sharma, T.5
  • 11
    • 53249088295 scopus 로고    scopus 로고
    • Impaired sensorimotor gating of the acoustic startle response in the prodrome of schizophrenia
    • 11 Quednow, B.B., Frommann, I., Berning, J., Kuhn, K.U., Maier, W., Wagner, M., Impaired sensorimotor gating of the acoustic startle response in the prodrome of schizophrenia. Biol Psychiatry 64 (2008), 766–773.
    • (2008) Biol Psychiatry , vol.64 , pp. 766-773
    • Quednow, B.B.1    Frommann, I.2    Berning, J.3    Kuhn, K.U.4    Maier, W.5    Wagner, M.6
  • 12
    • 57349086379 scopus 로고    scopus 로고
    • Improvement of prepulse inhibition and executive function by the COMT inhibitor tolcapone depends on COMT Val158Met polymorphism
    • 12 Giakoumaki, S.G., Roussos, P., Bitsios, P., Improvement of prepulse inhibition and executive function by the COMT inhibitor tolcapone depends on COMT Val158Met polymorphism. Neuropsychopharmacology 33 (2008), 3058–3068.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 3058-3068
    • Giakoumaki, S.G.1    Roussos, P.2    Bitsios, P.3
  • 13
    • 79951646083 scopus 로고    scopus 로고
    • The influence of schizophrenia-related neuregulin-1 polymorphisms on sensorimotor gating in healthy males
    • 13 Roussos, P., Giakoumaki, S.G., Adamaki, E., Bitsios, P., The influence of schizophrenia-related neuregulin-1 polymorphisms on sensorimotor gating in healthy males. Biol Psychiatry 69 (2011), 479–486.
    • (2011) Biol Psychiatry , vol.69 , pp. 479-486
    • Roussos, P.1    Giakoumaki, S.G.2    Adamaki, E.3    Bitsios, P.4
  • 14
    • 79958837359 scopus 로고    scopus 로고
    • The association of schizophrenia risk D-amino acid oxidase polymorphisms with sensorimotor gating, working memory and personality in healthy males
    • 14 Roussos, P., Giakoumaki, S.G., Adamaki, E., Georgakopoulos, A., Robakis, N.K., Bitsios, P., The association of schizophrenia risk D-amino acid oxidase polymorphisms with sensorimotor gating, working memory and personality in healthy males. Neuropsychopharmacology 36 (2011), 1677–1688.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 1677-1688
    • Roussos, P.1    Giakoumaki, S.G.2    Adamaki, E.3    Georgakopoulos, A.4    Robakis, N.K.5    Bitsios, P.6
  • 15
    • 46249088628 scopus 로고    scopus 로고
    • The dopamine D(3) receptor Ser9Gly polymorphism modulates prepulse inhibition of the acoustic startle reflex
    • 15 Roussos, P., Giakoumaki, S.G., Bitsios, P., The dopamine D(3) receptor Ser9Gly polymorphism modulates prepulse inhibition of the acoustic startle reflex. Biol Psychiatry 64 (2008), 235–240.
    • (2008) Biol Psychiatry , vol.64 , pp. 235-240
    • Roussos, P.1    Giakoumaki, S.G.2    Bitsios, P.3
  • 16
    • 70350702680 scopus 로고    scopus 로고
    • Tolcapone effects on gating, working memory, and mood interact with the synonymous catechol-O-methyltransferase rs4818c/g polymorphism
    • 16 Roussos, P., Giakoumaki, S.G., Bitsios, P., Tolcapone effects on gating, working memory, and mood interact with the synonymous catechol-O-methyltransferase rs4818c/g polymorphism. Biol Psychiatry 66 (2009), 997–1004.
    • (2009) Biol Psychiatry , vol.66 , pp. 997-1004
    • Roussos, P.1    Giakoumaki, S.G.2    Bitsios, P.3
  • 17
    • 67349160223 scopus 로고    scopus 로고
    • A risk PRODH haplotype affects sensorimotor gating, memory, schizotypy, and anxiety in healthy male subjects
    • 17 Roussos, P., Giakoumaki, S.G., Bitsios, P., A risk PRODH haplotype affects sensorimotor gating, memory, schizotypy, and anxiety in healthy male subjects. Biol Psychiatry 65 (2009), 1063–1070.
    • (2009) Biol Psychiatry , vol.65 , pp. 1063-1070
    • Roussos, P.1    Giakoumaki, S.G.2    Bitsios, P.3
  • 18
    • 46849120124 scopus 로고    scopus 로고
    • Prepulse inhibition of the startle reflex depends on the catechol O-methyltransferase Val158Met gene polymorphism
    • 18 Roussos, P., Giakoumaki, S.G., Rogdaki, M., Pavlakis, S., Frangou, S., Bitsios, P., Prepulse inhibition of the startle reflex depends on the catechol O-methyltransferase Val158Met gene polymorphism. Psychol Med 38 (2008), 1651–1658.
    • (2008) Psychol Med , vol.38 , pp. 1651-1658
    • Roussos, P.1    Giakoumaki, S.G.2    Rogdaki, M.3    Pavlakis, S.4    Frangou, S.5    Bitsios, P.6
  • 19
    • 80051953863 scopus 로고    scopus 로고
    • Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia
    • 19 Greenwood, T.A., Lazzeroni, L.C., Murray, S.S., Cadenhead, K.S., Calkins, M.E., Dobie, D.J., et al. Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am J Psychiatry 168 (2011), 930–946.
    • (2011) Am J Psychiatry , vol.168 , pp. 930-946
    • Greenwood, T.A.1    Lazzeroni, L.C.2    Murray, S.S.3    Cadenhead, K.S.4    Calkins, M.E.5    Dobie, D.J.6
  • 20
    • 77952420982 scopus 로고    scopus 로고
    • Sensorimotor gating is associated with CHRNA3 polymorphisms in schizophrenia and healthy volunteers
    • 20 Petrovsky, N., Quednow, B.B., Ettinger, U., Schmechtig, A., Mossner, R., Collier, D.A., et al. Sensorimotor gating is associated with CHRNA3 polymorphisms in schizophrenia and healthy volunteers. Neuropsychopharmacology 35 (2010), 1429–1439.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1429-1439
    • Petrovsky, N.1    Quednow, B.B.2    Ettinger, U.3    Schmechtig, A.4    Mossner, R.5    Collier, D.A.6
  • 21
    • 79955766426 scopus 로고    scopus 로고
    • The schizophrenia risk allele C of the TCF4 rs9960767 polymorphism disrupts sensorimotor gating in schizophrenia spectrum and healthy volunteers
    • 21 Quednow, B.B., Ettinger, U., Mossner, R., Rujescu, D., Giegling, I., Collier, D.A., et al. The schizophrenia risk allele C of the TCF4 rs9960767 polymorphism disrupts sensorimotor gating in schizophrenia spectrum and healthy volunteers. J Neurosci 31 (2011), 6684–6691.
    • (2011) J Neurosci , vol.31 , pp. 6684-6691
    • Quednow, B.B.1    Ettinger, U.2    Mossner, R.3    Rujescu, D.4    Giegling, I.5    Collier, D.A.6
  • 22
    • 69249221358 scopus 로고    scopus 로고
    • Sensorimotor gating depends on polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase, but not on neuregulin-1 Arg38Gln genotype: A replication study
    • 22 Quednow, B.B., Schmechtig, A., Ettinger, U., Petrovsky, N., Collier, D.A., Vollenweider, F.X., et al. Sensorimotor gating depends on polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase, but not on neuregulin-1 Arg38Gln genotype: A replication study. Biol Psychiatry 66 (2009), 614–620.
    • (2009) Biol Psychiatry , vol.66 , pp. 614-620
    • Quednow, B.B.1    Schmechtig, A.2    Ettinger, U.3    Petrovsky, N.4    Collier, D.A.5    Vollenweider, F.X.6
  • 23
    • 77749264489 scopus 로고    scopus 로고
    • Sensorimotor gating of schizophrenia patients depends on catechol O-methyltransferase Val158Met polymorphism
    • 23 Quednow, B.B., Wagner, M., Mossner, R., Maier, W., Kuhn, K.U., Sensorimotor gating of schizophrenia patients depends on catechol O-methyltransferase Val158Met polymorphism. Schizophr Bull 36 (2010), 341–346.
    • (2010) Schizophr Bull , vol.36 , pp. 341-346
    • Quednow, B.B.1    Wagner, M.2    Mossner, R.3    Maier, W.4    Kuhn, K.U.5
  • 24
    • 36849047394 scopus 로고    scopus 로고
    • Evidence of missense mutations on the neuregulin 1 gene affecting function of prepulse inhibition
    • 24 Hong, L.E., Wonodi, I., Stine, O.C., Mitchell, B.D., Thaker, G.K., Evidence of missense mutations on the neuregulin 1 gene affecting function of prepulse inhibition. Biol Psychiatry 63 (2008), 17–23.
    • (2008) Biol Psychiatry , vol.63 , pp. 17-23
    • Hong, L.E.1    Wonodi, I.2    Stine, O.C.3    Mitchell, B.D.4    Thaker, G.K.5
  • 25
    • 0032421570 scopus 로고    scopus 로고
    • The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10
    • quiz 34–57
    • 25 Sheehan, D.V., Lecrubier, Y., Sheehan, K.H., Amorim, P., Janavs, J., Weiller, E., et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 59:suppl 20 (1998), 22–33 quiz 34–57.
    • (1998) J Clin Psychiatry , vol.59 , pp. 22-33
    • Sheehan, D.V.1    Lecrubier, Y.2    Sheehan, K.H.3    Amorim, P.4    Janavs, J.5    Weiller, E.6
  • 26
    • 84995980203 scopus 로고    scopus 로고
    • Manual for Raven's Progressive Matrices and Vocabulary Scales. Section 3:
    • Harcourt Assessment San Antonio, TX
    • 26 Raven, J., Raven, J.C., Court, J.H., Manual for Raven's Progressive Matrices and Vocabulary Scales. Section 3:. The Standard Progressive Matrices, 2004, Harcourt Assessment, San Antonio, TX.
    • (2004) The Standard Progressive Matrices
    • Raven, J.1    Raven, J.C.2    Court, J.H.3
  • 27
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • 27 Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M.A., Bender, D., et al. PLINK: A tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81 (2007), 559–575.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.5    Bender, D.6
  • 28
    • 84871952176 scopus 로고    scopus 로고
    • Improved whole-chromosome phasing for disease and population genetic studies
    • 28 Delaneau, O., Zagury, J.F., Marchini, J., Improved whole-chromosome phasing for disease and population genetic studies. Nat Methods 10 (2013), 5–6.
    • (2013) Nat Methods , vol.10 , pp. 5-6
    • Delaneau, O.1    Zagury, J.F.2    Marchini, J.3
  • 29
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • 29 Howie, B.N., Donnelly, P., Marchini, J., A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet, 5, 2009, e1000529.
    • (2009) PLoS Genet , vol.5 , pp. e1000529
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 30
    • 80055015161 scopus 로고    scopus 로고
    • Temporal dynamics and genetic control of transcription in the human prefrontal cortex
    • 30 Colantuoni, C., Lipska, B.K., Ye, T., Hyde, T.M., Tao, R., Leek, J.T., et al. Temporal dynamics and genetic control of transcription in the human prefrontal cortex. Nature 478 (2011), 519–523.
    • (2011) Nature , vol.478 , pp. 519-523
    • Colantuoni, C.1    Lipska, B.K.2    Ye, T.3    Hyde, T.M.4    Tao, R.5    Leek, J.T.6
  • 31
    • 77953223693 scopus 로고    scopus 로고
    • Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain
    • 31 Gibbs, J.R., van der Brug, M.P., Hernandez, D.G., Traynor, B.J., Nalls, M.A., Lai, S.L., et al. Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genet, 6, 2010, e1000952.
    • (2010) PLoS Genet , vol.6 , pp. e1000952
    • Gibbs, J.R.1    van der Brug, M.P.2    Hernandez, D.G.3    Traynor, B.J.4    Nalls, M.A.5    Lai, S.L.6
  • 32
    • 84876907931 scopus 로고    scopus 로고
    • Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease
    • 32 Zhang, B., Gaiteri, C., Bodea, L.G., Wang, Z., McElwee, J., Podtelezhnikov, A.A., et al. Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease. Cell 153 (2013), 707–720.
    • (2013) Cell , vol.153 , pp. 707-720
    • Zhang, B.1    Gaiteri, C.2    Bodea, L.G.3    Wang, Z.4    McElwee, J.5    Podtelezhnikov, A.A.6
  • 34
    • 77955505742 scopus 로고    scopus 로고
    • A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies
    • 34 Stegle, O., Parts, L., Durbin, R., Winn, J., A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies. PLoS Comput Biol, 6, 2010, e1000770.
    • (2010) PLoS Comput Biol , vol.6 , pp. e1000770
    • Stegle, O.1    Parts, L.2    Durbin, R.3    Winn, J.4
  • 35
    • 84879653976 scopus 로고    scopus 로고
    • Effectively identifying eQTLs from multiple tissues by combining mixed model and meta-analytic approaches
    • 35 Sul, J.H., Han, B., Ye, C., Choi, T., Eskin, E., Effectively identifying eQTLs from multiple tissues by combining mixed model and meta-analytic approaches. PLoS Genet, 9, 2013, e1003491.
    • (2013) PLoS Genet , vol.9 , pp. e1003491
    • Sul, J.H.1    Han, B.2    Ye, C.3    Choi, T.4    Eskin, E.5
  • 36
    • 79955860273 scopus 로고    scopus 로고
    • Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies
    • 36 Han, B., Eskin, E., Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. Am J Hum Genet 88 (2011), 586–598.
    • (2011) Am J Hum Genet , vol.88 , pp. 586-598
    • Han, B.1    Eskin, E.2
  • 37
    • 84859246571 scopus 로고    scopus 로고
    • Interpreting meta-analyses of genome-wide association studies
    • 37 Han, B., Eskin, E., Interpreting meta-analyses of genome-wide association studies. PLoS Genet, 8, 2012, e1002555.
    • (2012) PLoS Genet , vol.8 , pp. e1002555
    • Han, B.1    Eskin, E.2
  • 40
    • 77954140531 scopus 로고    scopus 로고
    • Common SNPs explain a large proportion of the heritability for human height
    • 40 Yang, J., Benyamin, B., McEvoy, B.P., Gordon, S., Henders, A.K., Nyholt, D.R., et al. Common SNPs explain a large proportion of the heritability for human height. Nat Genet 42 (2010), 565–569.
    • (2010) Nat Genet , vol.42 , pp. 565-569
    • Yang, J.1    Benyamin, B.2    McEvoy, B.P.3    Gordon, S.4    Henders, A.K.5    Nyholt, D.R.6
  • 41
    • 77952367694 scopus 로고    scopus 로고
    • Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations
    • 41 Nica, A.C., Montgomery, S.B., Dimas, A.S., Stranger, B.E., Beazley, C., Barroso, I., Dermitzakis, E.T., Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations. PLoS Genet, 6, 2010, e1000895.
    • (2010) PLoS Genet , vol.6 , pp. e1000895
    • Nica, A.C.1    Montgomery, S.B.2    Dimas, A.S.3    Stranger, B.E.4    Beazley, C.5    Barroso, I.6    Dermitzakis, E.T.7
  • 42
    • 84866871814 scopus 로고    scopus 로고
    • Mapping cis- and trans-regulatory effects across multiple tissues in twins
    • 42 Grundberg, E., Small, K.S., Hedman, A.K., Nica, A.C., Buil, A., Keildson, S., et al. Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat Genet 44 (2012), 1084–1089.
    • (2012) Nat Genet , vol.44 , pp. 1084-1089
    • Grundberg, E.1    Small, K.S.2    Hedman, A.K.3    Nica, A.C.4    Buil, A.5    Keildson, S.6
  • 43
    • 0032714352 scopus 로고    scopus 로고
    • Genomic control for association studies
    • 43 Devlin, B., Roeder, K., Genomic control for association studies. Biometrics 55 (1999), 997–1004.
    • (1999) Biometrics , vol.55 , pp. 997-1004
    • Devlin, B.1    Roeder, K.2
  • 44
    • 77951439152 scopus 로고    scopus 로고
    • Trait-associated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS
    • 44 Nicolae, D.L., Gamazon, E., Zhang, W., Duan, S., Dolan, M.E., Cox, N.J., Trait-associated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS. PLoS Genet, 6, 2010, e1000888.
    • (2010) PLoS Genet , vol.6 , pp. e1000888
    • Nicolae, D.L.1    Gamazon, E.2    Zhang, W.3    Duan, S.4    Dolan, M.E.5    Cox, N.J.6
  • 45
    • 0345085551 scopus 로고    scopus 로고
    • Attentional modulation of short- and long-lead-interval modification of the acoustic startle eyeblink response: Comparing auditory and visual prestimuli
    • 45 Bohmelt, A.H., Schell, A.M., Dawson, M.E., Attentional modulation of short- and long-lead-interval modification of the acoustic startle eyeblink response: Comparing auditory and visual prestimuli. Int J Psychophysiol 32 (1999), 239–250.
    • (1999) Int J Psychophysiol , vol.32 , pp. 239-250
    • Bohmelt, A.H.1    Schell, A.M.2    Dawson, M.E.3
  • 46
    • 0034977783 scopus 로고    scopus 로고
    • Attentional stages of information processing during a continuous performance test: A startle modification analysis
    • 46 Hazlett, E.A., Dawson, M.E., Schell, A.M., Nuechterlein, K.H., Attentional stages of information processing during a continuous performance test: A startle modification analysis. Psychophysiology 38 (2001), 669–677.
    • (2001) Psychophysiology , vol.38 , pp. 669-677
    • Hazlett, E.A.1    Dawson, M.E.2    Schell, A.M.3    Nuechterlein, K.H.4
  • 47
    • 33645895263 scopus 로고    scopus 로고
    • The level of prepulse inhibition in healthy individuals may index cortical modulation of early information processing
    • 47 Giakoumaki, S.G., Bitsios, P., Frangou, S., The level of prepulse inhibition in healthy individuals may index cortical modulation of early information processing. Brain Res 1078 (2006), 168–170.
    • (2006) Brain Res , vol.1078 , pp. 168-170
    • Giakoumaki, S.G.1    Bitsios, P.2    Frangou, S.3
  • 48
    • 33745958262 scopus 로고    scopus 로고
    • Increased prepulse inhibition of the acoustic startle response is associated with better strategy formation and execution times in healthy males
    • 48 Bitsios, P., Giakoumaki, S.G., Theou, K., Frangou, S., Increased prepulse inhibition of the acoustic startle response is associated with better strategy formation and execution times in healthy males. Neuropsychologia 44 (2006), 2494–2499.
    • (2006) Neuropsychologia , vol.44 , pp. 2494-2499
    • Bitsios, P.1    Giakoumaki, S.G.2    Theou, K.3    Frangou, S.4
  • 50
    • 0029889571 scopus 로고    scopus 로고
    • A relationship between inhibition of the acoustic startle response and the protection of prepulse processing
    • 50 Norris, C., Blumenthal, T., A relationship between inhibition of the acoustic startle response and the protection of prepulse processing. Psychobiology 24 (1996), 160–168.
    • (1996) Psychobiology , vol.24 , pp. 160-168
    • Norris, C.1    Blumenthal, T.2
  • 51
    • 84876936728 scopus 로고    scopus 로고
    • Polygenic risk for schizophrenia is associated with cognitive change between childhood and old age
    • 51 McIntosh, A.M., Gow, A., Luciano, M., Davies, G., Liewald, D.C., Harris, S.E., et al. Polygenic risk for schizophrenia is associated with cognitive change between childhood and old age. Biol Psychiatry 73 (2013), 938–943.
    • (2013) Biol Psychiatry , vol.73 , pp. 938-943
    • McIntosh, A.M.1    Gow, A.2    Luciano, M.3    Davies, G.4    Liewald, D.C.5    Harris, S.E.6
  • 52
    • 84893661023 scopus 로고    scopus 로고
    • Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: A report from the Cognitive Genomics consorTium (COGENT)
    • 52 Lencz, T., Knowles, E., Davies, G., Guha, S., Liewald, D.C., Starr, J.M., et al. Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: A report from the Cognitive Genomics consorTium (COGENT). Mol Psychiatry 19 (2014), 168–174.
    • (2014) Mol Psychiatry , vol.19 , pp. 168-174
    • Lencz, T.1    Knowles, E.2    Davies, G.3    Guha, S.4    Liewald, D.C.5    Starr, J.M.6
  • 53
    • 0037762690 scopus 로고    scopus 로고
    • Neurotrophins and their receptors: A convergence point for many signalling pathways
    • 53 Chao, M.V., Neurotrophins and their receptors: A convergence point for many signalling pathways. Nat Rev Neurosci 4 (2003), 299–309.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 299-309
    • Chao, M.V.1
  • 54
    • 0028816634 scopus 로고
    • Regulation of voltage-gated ion channels by NGF and ciliary neurotrophic factor in SK-N-SH neuroblastoma cells
    • 54 Lesser, S.S., Lo, D.C., Regulation of voltage-gated ion channels by NGF and ciliary neurotrophic factor in SK-N-SH neuroblastoma cells. J Neurosci 15 (1995), 253–261.
    • (1995) J Neurosci , vol.15 , pp. 253-261
    • Lesser, S.S.1    Lo, D.C.2
  • 55
    • 67049110323 scopus 로고    scopus 로고
    • Calneurons provide a calcium threshold for trans-Golgi network to plasma membrane trafficking
    • 55 Mikhaylova, M., Reddy, P.P., Munsch, T., Landgraf, P., Suman, S.K., Smalla, K.H., et al. Calneurons provide a calcium threshold for trans-Golgi network to plasma membrane trafficking. Proc Natl Acad Sci U S A 106 (2009), 9093–9098.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9093-9098
    • Mikhaylova, M.1    Reddy, P.P.2    Munsch, T.3    Landgraf, P.4    Suman, S.K.5    Smalla, K.H.6
  • 56
    • 0037215606 scopus 로고    scopus 로고
    • Blockade of phencyclidine-induced cortical apoptosis and deficits in prepulse inhibition by M40403, a superoxide dismutase mimetic
    • 56 Wang, C., McInnis, J., West, J.B., Bao, J., Anastasio, N., Guidry, J.A., et al. Blockade of phencyclidine-induced cortical apoptosis and deficits in prepulse inhibition by M40403, a superoxide dismutase mimetic. J Pharmacol Exp Ther 304 (2003), 266–271.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 266-271
    • Wang, C.1    McInnis, J.2    West, J.B.3    Bao, J.4    Anastasio, N.5    Guidry, J.A.6
  • 57
    • 0141593501 scopus 로고    scopus 로고
    • Long-term behavioural, molecular and morphological effects of neonatal NMDA receptor antagonism
    • 57 Harris, L.W., Sharp, T., Gartlon, J., Jones, D.N., Harrison, P.J., Long-term behavioural, molecular and morphological effects of neonatal NMDA receptor antagonism. Eur J Neurosci 18 (2003), 1706–1710.
    • (2003) Eur J Neurosci , vol.18 , pp. 1706-1710
    • Harris, L.W.1    Sharp, T.2    Gartlon, J.3    Jones, D.N.4    Harrison, P.J.5
  • 58
    • 13244258251 scopus 로고    scopus 로고
    • Prepulse inhibition of the acoustically evoked startle reflex in patients with an acute schizophrenic psychosis—a longitudinal study
    • 58 Meincke, U., Morth, D., Voss, T., Thelen, B., Geyer, M.A., Gouzoulis-Mayfrank, E., Prepulse inhibition of the acoustically evoked startle reflex in patients with an acute schizophrenic psychosis—a longitudinal study. Eur Arch Psychiatry Clin Neurosci 254 (2004), 415–421.
    • (2004) Eur Arch Psychiatry Clin Neurosci , vol.254 , pp. 415-421
    • Meincke, U.1    Morth, D.2    Voss, T.3    Thelen, B.4    Geyer, M.A.5    Gouzoulis-Mayfrank, E.6
  • 59
    • 33845325470 scopus 로고    scopus 로고
    • Startle gating deficits in a large cohort of patients with schizophrenia: Relationship to medications, symptoms, neurocognition, and level of function
    • 59 Swerdlow, N.R., Light, G.A., Cadenhead, K.S., Sprock, J., Hsieh, M.H., Braff, D.L., Startle gating deficits in a large cohort of patients with schizophrenia: Relationship to medications, symptoms, neurocognition, and level of function. Arch Gen Psychiatry 63 (2006), 1325–1335.
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 1325-1335
    • Swerdlow, N.R.1    Light, G.A.2    Cadenhead, K.S.3    Sprock, J.4    Hsieh, M.H.5    Braff, D.L.6


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