Adeno-associated virus (AAV) dual vector strategies for gene therapy encoding large transgenes

Yale Journal of Biology and Medicine

Volumn 90, Issue 4, 2017, Pages 611-623

  McClements, Michelle E ^a   Maclaren, Robert E ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b OXFORD EYE HOSPITAL   (United Kingdom)

Author keywords

AAV; Dual vector; Gene therapy; Large transgenes

Indexed keywords

ADENO ASSOCIATED VIRUS VECTOR; MYOSIN VIIA; SINGLE STRANDED DNA;

DNA END JOINING REPAIR; GENE EXPRESSION; GENE SEQUENCE; GENETIC CODE; GENETIC ENGINEERING; GENETIC TRANSCRIPTION; GENOMIC FRAGMENT; HOMOLOGOUS RECOMBINATION; HUMAN; NONHUMAN; RECOMBINANT GENE; REVIEW; RNA SPLICING; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; TRANS SPLICING; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; ANIMAL; DEPENDOPARVOVIRUS; GENE THERAPY; GENE VECTOR; GENETICS; LONG TERMINAL REPEAT; PROCEDURES; RETINA DEGENERATION;

ANIMALS; DEPENDOVIRUS; DNA, SINGLE-STRANDED; GENETIC THERAPY; GENETIC VECTORS; HUMANS; RETINAL DEGENERATION; TERMINAL REPEAT SEQUENCES; TRANSGENES;

EID: 85038598841     PISSN: 00440086     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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