Increasing the size of rAAV-mediated expression cassettes in vivo by intermolecular joining of two complementary vectors

Nature Biotechnology

Volumn 18, Issue 5, 2000, Pages 527-532

  Nakai, Hiroyuki ^a   Storm, Theresa A ^a   Kay, Mark A ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

Adeno associated virus vector; Concatemer; Gene therapy; Hepatocytes; Intermolecular recombination

Indexed keywords

COMPLEMENTARY DNA; ELONGATION FACTOR 1ALPHA; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA PACKAGING; DNA SEQUENCE; ENHANCER REGION; ESCHERICHIA COLI; GENE CASSETTE; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; MALE; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENE; VIRUS RECOMBINANT;

ANIMALS; BETA-GALACTOSIDASE; DEPENDOVIRUS; GENE THERAPY; GENETIC VECTORS; INJECTIONS, INTRAVENOUS; LAC OPERON; LIVER; MICE; PEPTIDE ELONGATION FACTOR 1; PORTAL VEIN; RECOMBINANT PROTEINS; RECOMBINATION, GENETIC; TRANSGENES;

ADENO-ASSOCIATED VIRUS; ANIMALIA; DNA VIRUSES; ESCHERICHIA COLI;

EID: 0034033447     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/75390     Document Type: Article

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