Homologous recombination mediates functional recovery of dysferlin deficiency following AAV5 gene transfer

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Grose, William E ^a,b   Clark, K Reed ^a,b   Griffin, Danielle ^a,b   Malik, Vinod ^a,b   Shontz, Kimberly M ^a,b   Montgomery, Chrystal L ^a,b   Lewis, Sarah ^a,b   Brown, Robert H ^c   Janssen, Paul M L ^a   Mendell, Jerry R ^a,b   Rodino Klapac, Louise R ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; COMPLEMENTARY DNA; DYSFERLIN; MESSENGER RNA;

ADENO ASSOCIATED VIRUS; ADENO ASSOCIATED VIRUS 5; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DYSFERLINOPATHY; ECCENTRIC MUSCLE CONTRACTION; GENE REPLACEMENT THERAPY; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; HOMOLOGOUS RECOMBINATION; IMMUNOHISTOCHEMISTRY; IN VIVO GENE TRANSFER; LEG MUSCLE; MOUSE; MUSCLE FATIGUE; MUSCLE TETANIC CONTRACTION; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING;

EID: 84862487885     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039233     Document Type: Article

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