메뉴 건너뛰기




Volumn 8, Issue 1, 2017, Pages

Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling

Author keywords

[No Author keywords available]

Indexed keywords

DECAY ACCELERATING FACTOR; RNA; TRANSCRIPTOME;

EID: 85034642667     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-01560-x     Document Type: Article
Times cited : (142)

References (64)
  • 1
    • 84929515988 scopus 로고    scopus 로고
    • Mammary gland development: Cell fate specification, stem cells and the microenvironment
    • Inman, J. L., Robertson, C., Mott, J. D. &Bissell, M. J. Mammary gland development: cell fate specification, stem cells and the microenvironment. Development 142, 1028-1042 (2015).
    • (2015) Development , vol.142 , pp. 1028-1042
    • Inman, J.L.1    Robertson, C.2    Mott, J.D.3    Bissell, M.J.4
  • 2
    • 84901758365 scopus 로고    scopus 로고
    • Mammary stem cells and the differentiation hierarchy: Current status and perspectives
    • Visvader, J. E. &Stingl, J. Mammary stem cells and the differentiation hierarchy: current status and perspectives. Genes Dev. 28, 1143-1158 (2014).
    • (2014) Genes Dev. , vol.28 , pp. 1143-1158
    • Visvader, J.E.1    Stingl, J.2
  • 4
    • 58949085251 scopus 로고    scopus 로고
    • Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate
    • Kendrick, H. et al. Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate. BMC Genomics 9, 591 (2008).
    • (2008) BMC Genomics , vol.9 , pp. 591
    • Kendrick, H.1
  • 5
    • 77955895963 scopus 로고    scopus 로고
    • Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
    • Lim, E. et al. Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways. Breast Cancer Res. 12, R21 (2010).
    • (2010) Breast Cancer Res. , vol.12 , pp. R21
    • Lim, E.1
  • 6
    • 48649096223 scopus 로고    scopus 로고
    • Transcriptome analysis of the normal human mammary cell commitment and differentiation process
    • Raouf, A. et al. Transcriptome analysis of the normal human mammary cell commitment and differentiation process. Cell Stem Cell 3, 109-118 (2008).
    • (2008) Cell Stem Cell , vol.3 , pp. 109-118
    • Raouf, A.1
  • 7
    • 84867639947 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of the luminal cell hierarchy of the mammary gland
    • Shehata, M. et al. Phenotypic and functional characterization of the luminal cell hierarchy of the mammary gland. Breast Cancer Res. 14, R134 (2012).
    • (2012) Breast Cancer Res. , vol.14 , pp. R134
    • Shehata, M.1
  • 8
    • 84927937537 scopus 로고    scopus 로고
    • A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1
    • Sheridan, J. M. et al. A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1. BMC Cancer 15, 221 (2015).
    • (2015) BMC Cancer , vol.15 , pp. 221
    • Sheridan, J.M.1
  • 9
    • 84922321862 scopus 로고    scopus 로고
    • Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex
    • Pollen, A. A. et al. Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex. Nat. Biotechnol. 32, 1053-1058 (2014).
    • (2014) Nat. Biotechnol. , vol.32 , pp. 1053-1058
    • Pollen, A.A.1
  • 10
    • 84997343111 scopus 로고    scopus 로고
    • Single-cell resolution of temporal gene expression during Heart development
    • DeLaughter, D. M. et al. Single-cell resolution of temporal gene expression during Heart development. Dev. Cell 39, 480-490 (2016).
    • (2016) Dev. Cell , vol.39 , pp. 480-490
    • DeLaughter, D.M.1
  • 11
    • 84930227326 scopus 로고    scopus 로고
    • Single-cell transcriptome analyses reveal signals to activate dormant neural stem cells
    • Luo, Y. et al. Single-cell transcriptome analyses reveal signals to activate dormant neural stem cells. Cell 161, 1175-1186 (2015).
    • (2015) Cell , vol.161 , pp. 1175-1186
    • Luo, Y.1
  • 12
    • 84900529199 scopus 로고    scopus 로고
    • Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq
    • Treutlein, B. et al. Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq. Nature 509, 371-375 (2014).
    • (2014) Nature , vol.509 , pp. 371-375
    • Treutlein, B.1
  • 13
    • 84941201582 scopus 로고    scopus 로고
    • Single-cell messenger RNA sequencing reveals rare intestinal cell types
    • Grun, D. et al. Single-cell messenger RNA sequencing reveals rare intestinal cell types. Nature 525, 251-255 (2015).
    • (2015) Nature , vol.525 , pp. 251-255
    • Grun, D.1
  • 14
    • 84949035291 scopus 로고    scopus 로고
    • Single-cell transcriptomics reveals receptor transformations during olfactory neurogenesis
    • Hanchate, N. K. et al. Single-cell transcriptomics reveals receptor transformations during olfactory neurogenesis. Science 350, 1251-1255 (2015).
    • (2015) Science , vol.350 , pp. 1251-1255
    • Hanchate, N.K.1
  • 15
    • 84994589702 scopus 로고    scopus 로고
    • Single-cell analysis uncovers clonal acinar cell heterogeneity in the adult pancreas
    • Wollny, D. et al. Single-cell analysis uncovers clonal acinar cell heterogeneity in the adult pancreas. Dev. Cell 39, 289-301 (2016).
    • (2016) Dev. Cell , vol.39 , pp. 289-301
    • Wollny, D.1
  • 16
    • 84975473183 scopus 로고    scopus 로고
    • Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq
    • Treutlein, B. et al. Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq. Nature 534, 391-395 (2016).
    • (2016) Nature , vol.534 , pp. 391-395
    • Treutlein, B.1
  • 17
    • 84989962489 scopus 로고    scopus 로고
    • Single-cell analysis of mixed-lineage states leading to a binary cell fate choice
    • Olsson, A. et al. Single-cell analysis of mixed-lineage states leading to a binary cell fate choice. Nature 537, 698-702 (2016).
    • (2016) Nature , vol.537 , pp. 698-702
    • Olsson, A.1
  • 18
    • 84885172419 scopus 로고    scopus 로고
    • Mapping cellular hierarchy by single-cell analysis of the cell surface repertoire
    • Guo, G. et al. Mapping cellular hierarchy by single-cell analysis of the cell surface repertoire. Cell Stem Cell 13, 492-505 (2013).
    • (2013) Cell Stem Cell , vol.13 , pp. 492-505
    • Guo, G.1
  • 19
    • 84990895380 scopus 로고    scopus 로고
    • De novo prediction of stem cell identity using single-cell transcriptome data
    • Grun, D. et al. De novo prediction of stem cell identity using single-cell transcriptome data. Cell Stem Cell 19, 266-277 (2016).
    • (2016) Cell Stem Cell , vol.19 , pp. 266-277
    • Grun, D.1
  • 20
    • 84981744785 scopus 로고    scopus 로고
    • Single-cell transcript profiles reveal multilineage priming in early progenitors derived from Lgr5(+) intestinal stem cells
    • Kim, T. H. et al. Single-cell transcript profiles reveal multilineage priming in early progenitors derived from Lgr5(+) intestinal stem cells. Cell Rep. 16, 2053-2060 (2016).
    • (2016) Cell Rep. , vol.16 , pp. 2053-2060
    • Kim, T.H.1
  • 21
    • 85009446777 scopus 로고    scopus 로고
    • Massively parallel digital transcriptional profiling of single cells
    • Zheng, G. X. et al. Massively parallel digital transcriptional profiling of single cells. Nat. Commun. 8, 14049 (2017).
    • (2017) Nat. Commun. , vol.8 , pp. 14049
    • Zheng, G.X.1
  • 22
    • 84925969713 scopus 로고    scopus 로고
    • EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival
    • Fu, N. Y. et al. EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival. Nat. Cell Biol. 17, 365-375 (2015).
    • (2015) Nat. Cell Biol. , vol.17 , pp. 365-375
    • Fu, N.Y.1
  • 23
    • 84883166387 scopus 로고    scopus 로고
    • Developmental changes in the in vitro activated regenerative activity of primitive mammary epithelial cells
    • Makarem, M. et al. Developmental changes in the in vitro activated regenerative activity of primitive mammary epithelial cells. PLoS Biol. 11, e1001630 (2013).
    • (2013) PLoS Biol. , vol.11 , pp. e1001630
    • Makarem, M.1
  • 24
    • 84863012487 scopus 로고    scopus 로고
    • A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer
    • Spike, B. T. et al. A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer. Cell Stem Cell 10, 183-197 (2012).
    • (2012) Cell Stem Cell , vol.10 , pp. 183-197
    • Spike, B.T.1
  • 25
    • 84924242267 scopus 로고    scopus 로고
    • Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland
    • Boras-Granic, K., Dann, P. &Wysolmerski, J. J. Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland. Breast Cancer Res. 16, 487 (2014).
    • (2014) Breast Cancer Res. , vol.16 , pp. 487
    • Boras-Granic, K.1    Dann, P.2    Wysolmerski, J.J.3
  • 26
    • 85012263772 scopus 로고    scopus 로고
    • Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive
    • Fu, N. Y. et al. Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive. Nat Cell Biol 19, 164-176 (2017).
    • (2017) Nat Cell Biol , vol.19 , pp. 164-176
    • Fu, N.Y.1
  • 27
    • 84903616029 scopus 로고    scopus 로고
    • Single-cell western blotting
    • Hughes, A. J. et al. Single-cell western blotting. Nat. Methods 11, 749-755 (2014).
    • (2014) Nat. Methods , vol.11 , pp. 749-755
    • Hughes, A.J.1
  • 28
    • 0037345836 scopus 로고    scopus 로고
    • Netrin-1/ neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis
    • Srinivasan, K., Strickland, P., Valdes, A., Shin, G. C. &Hinck, L. Netrin-1/ neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis. Dev. Cell 4, 371-382 (2003).
    • (2003) Dev. Cell , vol.4 , pp. 371-382
    • Srinivasan, K.1    Strickland, P.2    Valdes, A.3    Shin, G.C.4    Hinck, L.5
  • 29
    • 33645536314 scopus 로고    scopus 로고
    • Slit2 and netrin 1 act synergistically as adhesive cues to generate tubular bi-layers during ductal morphogenesis
    • Strickland, P., Shin, G. C., Plump, A., Tessier-Lavigne, M. &Hinck, L. Slit2 and netrin 1 act synergistically as adhesive cues to generate tubular bi-layers during ductal morphogenesis. Development 133, 823-832 (2006).
    • (2006) Development , vol.133 , pp. 823-832
    • Strickland, P.1    Shin, G.C.2    Plump, A.3    Tessier-Lavigne, M.4    Hinck, L.5
  • 30
    • 78649396592 scopus 로고    scopus 로고
    • The SUMO pathway: Emerging mechanisms that shape specificity, conjugation and recognition
    • Gareau, J. R. &Lima, C. D. The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition. Nat. Rev. Mol. Cell Biol. 11, 861-871 (2010).
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 861-871
    • Gareau, J.R.1    Lima, C.D.2
  • 31
    • 78751534200 scopus 로고    scopus 로고
    • Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation
    • Snider, N. T., Weerasinghe, S. V., Iniguez-Lluhi, J. A., Herrmann, H. &Omary, M. B. Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation. J. Biol. Chem. 286, 2273-2284 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 2273-2284
    • Snider, N.T.1    Weerasinghe, S.V.2    Iniguez-Lluhi, J.A.3    Herrmann, H.4    Omary, M.B.5
  • 32
    • 85016139022 scopus 로고    scopus 로고
    • Identity and dynamics of mammary stem cells during branching morphogenesis
    • Scheele, C. L. G. J. et al. Identity and dynamics of mammary stem cells during branching morphogenesis. Nature 542, 313-317 (2017).
    • (2017) Nature , vol.542 , pp. 313-317
    • Scheele, C.L.G.J.1
  • 33
    • 83255186736 scopus 로고    scopus 로고
    • Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14
    • Asselin-Labat, M. L. et al. Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14. Mol. Cell Biol. 31, 4609-4622 (2011).
    • (2011) Mol. Cell Biol. , vol.31 , pp. 4609-4622
    • Asselin-Labat, M.L.1
  • 34
    • 57249084011 scopus 로고    scopus 로고
    • Visualizing high-dimensional data using t-SNE
    • van der Maaten, L. &Hinton, G. Visualizing high-dimensional data using t-SNE. J. Mach. Learn. Res. 9, 2579-2605 (2008).
    • (2008) J. Mach. Learn. Res. , vol.9 , pp. 2579-2605
    • Van Der Maaten, L.1    Hinton, G.2
  • 35
    • 84859602728 scopus 로고    scopus 로고
    • Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns
    • Sanchez-Freire, V., Ebert, A. D., Kalisky, T., Quake, S. R. &Wu, J. C. Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns. Nat. Protoc. 7, 829-838 (2012).
    • (2012) Nat. Protoc. , vol.7 , pp. 829-838
    • Sanchez-Freire, V.1    Ebert, A.D.2    Kalisky, T.3    Quake, S.R.4    Wu, J.C.5
  • 37
    • 0034887735 scopus 로고    scopus 로고
    • Cellular turnover in the mammary gland is correlated with systemic levels of progesterone and not 17beta-estradiol during the estrous cycle
    • Fata, J. E., Chaudhary, V. &Khokha, R. Cellular turnover in the mammary gland is correlated with systemic levels of progesterone and not 17beta-estradiol during the estrous cycle. Biol. Reprod. 65, 680-688 (2001).
    • (2001) Biol. Reprod. , vol.65 , pp. 680-688
    • Fata, J.E.1    Chaudhary, V.2    Khokha, R.3
  • 38
    • 84878258729 scopus 로고    scopus 로고
    • Progesterone signalling in breast cancer: A neglected hormone coming into the limelight
    • Brisken, C. Progesterone signalling in breast cancer: a neglected hormone coming into the limelight. Nat. Rev. Cancer 13, 385-396 (2013).
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 385-396
    • Brisken, C.1
  • 39
    • 84874231902 scopus 로고    scopus 로고
    • Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2
    • Pal, B. et al. Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2. Cell Rep. 3, 411-426 (2013).
    • (2013) Cell Rep. , vol.3 , pp. 411-426
    • Pal, B.1
  • 40
    • 77953388315 scopus 로고    scopus 로고
    • Progesterone induces adult mammary stem cell expansion
    • Joshi, P. A. et al. Progesterone induces adult mammary stem cell expansion. Nature 465, 803-807 (2010).
    • (2010) Nature , vol.465 , pp. 803-807
    • Joshi, P.A.1
  • 41
    • 77953384898 scopus 로고    scopus 로고
    • Control of mammary stem cell function by steroid hormone signalling
    • Asselin-Labat, M. L. et al. Control of mammary stem cell function by steroid hormone signalling. Nature 465, 798-802 (2010).
    • (2010) Nature , vol.465 , pp. 798-802
    • Asselin-Labat, M.L.1
  • 42
    • 84922541996 scopus 로고    scopus 로고
    • Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis
    • Cabezas-Wallscheid, N. et al. Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis. Cell Stem Cell 15, 507-522 (2014).
    • (2014) Cell Stem Cell , vol.15 , pp. 507-522
    • Cabezas-Wallscheid, N.1
  • 43
    • 0030954167 scopus 로고    scopus 로고
    • Multilineage gene expression precedes commitment in the hemopoietic system
    • Hu, M. et al. Multilineage gene expression precedes commitment in the hemopoietic system. Genes Dev. 11, 774-785 (1997).
    • (1997) Genes Dev. , vol.11 , pp. 774-785
    • Hu, M.1
  • 44
    • 33747196725 scopus 로고    scopus 로고
    • Multilineage transcriptional priming and determination of alternate hematopoietic cell fates
    • Laslo, P. et al. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell 126, 755-766 (2006).
    • (2006) Cell , vol.126 , pp. 755-766
    • Laslo, P.1
  • 45
    • 30144433093 scopus 로고    scopus 로고
    • Generation of a functional mammary gland from a single stem cell
    • Shackleton, M. et al. Generation of a functional mammary gland from a single stem cell. Nature 439, 84-88 (2006).
    • (2006) Nature , vol.439 , pp. 84-88
    • Shackleton, M.1
  • 46
    • 30144432901 scopus 로고    scopus 로고
    • Purification and unique properties of mammary epithelial stem cells
    • Stingl, J. et al. Purification and unique properties of mammary epithelial stem cells. Nature 439, 993-997 (2006).
    • (2006) Nature , vol.439 , pp. 993-997
    • Stingl, J.1
  • 47
    • 84940446838 scopus 로고    scopus 로고
    • Combined single-cell functional and gene expression analysis resolves heterogeneity within stem cell populations
    • Wilson, N. K. et al. Combined single-cell functional and gene expression analysis resolves heterogeneity within stem cell populations. Cell Stem Cell 16, 712-724 (2015).
    • (2015) Cell Stem Cell , vol.16 , pp. 712-724
    • Wilson, N.K.1
  • 48
    • 84936772243 scopus 로고    scopus 로고
    • Integration of microRNA signatures of distinct mammary epithelial cell types with their gene expression and epigenetic portraits
    • Pal, B. et al. Integration of microRNA signatures of distinct mammary epithelial cell types with their gene expression and epigenetic portraits. Breast Cancer Res. 17, 85 (2015).
    • (2015) Breast Cancer Res. , vol.17 , pp. 85
    • Pal, B.1
  • 49
    • 84856088648 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase activity is a biomarker of primitive normal human mammary luminal cells
    • Eirew, P. et al. Aldehyde dehydrogenase activity is a biomarker of primitive normal human mammary luminal cells. Stem Cells 30, 344-348 (2012).
    • (2012) Stem Cells , vol.30 , pp. 344-348
    • Eirew, P.1
  • 50
    • 84895922043 scopus 로고    scopus 로고
    • AXL induces epithelial-to-mesenchymal transition and regulates the function of breast cancer stem cells
    • Asiedu, M. K. et al. AXL induces epithelial-to-mesenchymal transition and regulates the function of breast cancer stem cells. Oncogene 33, 1316-1324 (2014).
    • (2014) Oncogene , vol.33 , pp. 1316-1324
    • Asiedu, M.K.1
  • 51
    • 84866114887 scopus 로고    scopus 로고
    • Developmental stage and time dictate the fate of Wnt/beta-catenin-responsive stem cells in the mammary gland
    • van Amerongen, R., Bowman, A. N. &Nusse, R. Developmental stage and time dictate the fate of Wnt/beta-catenin-responsive stem cells in the mammary gland. Cell Stem Cell 11, 387-400 (2012).
    • (2012) Cell Stem Cell , vol.11 , pp. 387-400
    • Van Amerongen, R.1    Bowman, A.N.2    Nusse, R.3
  • 52
    • 51049114270 scopus 로고    scopus 로고
    • Prognostic significance of CD55 expression in breast cancer
    • Ikeda, J. et al. Prognostic significance of CD55 expression in breast cancer. Clin. Cancer Res. 14, 4780-4786 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , pp. 4780-4786
    • Ikeda, J.1
  • 53
    • 84922129231 scopus 로고    scopus 로고
    • Identification of multipotent mammary stem cells by protein C receptor expression
    • Wang, D. et al. Identification of multipotent mammary stem cells by protein C receptor expression. Nature 517, 81-84 (2015).
    • (2015) Nature , vol.517 , pp. 81-84
    • Wang, D.1
  • 54
    • 85015695567 scopus 로고    scopus 로고
    • Human haematopoietic stem cell lineage commitment is a continuous process
    • Velten, L. et al. Human haematopoietic stem cell lineage commitment is a continuous process. Nat. Cell Biol. 19, 271-281 (2017).
    • (2017) Nat. Cell Biol. , vol.19 , pp. 271-281
    • Velten, L.1
  • 55
    • 84878580738 scopus 로고    scopus 로고
    • The Subread aligner: Fast, accurate and scalable read mapping by seed-and-vote
    • Liao, Y., Smyth, G. K. &Shi, W. The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote. Nucleic Acids Res. 41, e108 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , pp. e108
    • Liao, Y.1    Smyth, G.K.2    Shi, W.3
  • 56
    • 84897397058 scopus 로고    scopus 로고
    • FeatureCounts: An efficient general purpose program for assigning sequence reads to genomic features
    • Liao, Y., Smyth, G. K. &Shi, W. featureCounts: an efficient general purpose program for assigning sequence reads to genomic features. Bioinformatics 30, 923-930 (2014).
    • (2014) Bioinformatics , vol.30 , pp. 923-930
    • Liao, Y.1    Smyth, G.K.2    Shi, W.3
  • 57
    • 84858041341 scopus 로고    scopus 로고
    • Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation
    • McCarthy, D. J., Chen, Y. &Smyth, G. K. Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation. Nucleic Acids Res. 40, 4288-4297 (2012).
    • (2012) Nucleic Acids Res. , vol.40 , pp. 4288-4297
    • McCarthy, D.J.1    Chen, Y.2    Smyth, G.K.3
  • 58
    • 84926507971 scopus 로고    scopus 로고
    • Limma powers differential expression analyses for RNA-sequencing and microarray studies
    • Ritchie, M. E. et al. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 43, e47 (2015).
    • (2015) Nucleic Acids Res. , vol.43 , pp. e47
    • Ritchie, M.E.1
  • 60
    • 62549109118 scopus 로고    scopus 로고
    • Testing significance relative to a fold-change threshold is a TREAT
    • McCarthy, D. J. &Smyth, G. K. Testing significance relative to a fold-change threshold is a TREAT. Bioinformatics 25, 765-771 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 765-771
    • McCarthy, D.J.1    Smyth, G.K.2
  • 61
    • 73249119966 scopus 로고    scopus 로고
    • Towards the mammalian interactome: Inference of a core mammalian interaction set in mouse
    • Shin, C. J., Davis, M. J. &Ragan, M. A. Towards the mammalian interactome: Inference of a core mammalian interaction set in mouse. Proteomics 9, 5256-5266 (2009).
    • (2009) Proteomics , vol.9 , pp. 5256-5266
    • Shin, C.J.1    Davis, M.J.2    Ragan, M.A.3
  • 62
    • 85016041593 scopus 로고    scopus 로고
    • Mouse genome database (MGD)-2017: Community knowledge resource for the laboratory mouse
    • Blake, J. A. et al. Mouse genome database (MGD)-2017: community knowledge resource for the laboratory mouse. Nucleic Acids Res. 45, D723-D729 (2017).
    • (2017) Nucleic Acids Res. , vol.45 , pp. D723-D729
    • Blake, J.A.1
  • 63
    • 85006341634 scopus 로고    scopus 로고
    • Determining the significance of protein network features and attributes using permutation testing
    • Cursons, J. &Davis, M. J. Determining the significance of protein network features and attributes using permutation testing. Methods Mol. Biol. 1549, 199-208 (2017).
    • (2017) Methods Mol. Biol. , vol.1549 , pp. 199-208
    • Cursons, J.1    Davis, M.J.2
  • 64
    • 84894267586 scopus 로고    scopus 로고
    • In situ identification of bipotent stem cells in the mammary gland
    • Rios, A. C., Fu, N. Y., Lindeman, G. J. &Visvader, J. E. In situ identification of bipotent stem cells in the mammary gland. Nature 506, 322-327 (2014).
    • (2014) Nature , vol.506 , pp. 322-327
    • Rios, A.C.1    Fu, N.Y.2    Lindeman, G.J.3    Visvader, J.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.