A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1

BMC Cancer

Volumn 15, Issue 1, 2015, Pages

  Sheridan, Julie M ^a,b   Ritchie, Matthew E ^a,c   Best, Sarah A ^a,b   Jiang, Kun ^a   Beck, Tamara J ^a   Vaillant, François ^a,b   Liu, Kevin ^a   Dickins, Ross A ^a,b   Smyth, Gordon K ^a,c   Lindeman, Geoffrey J ^a,b,d   Visvader, Jane E ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Asap1; Mammary progenitor cells; Mammary stem cells; Mammosphere; Prox1; shRNA screen; Transcription factors

Indexed keywords

LENTIVIRUS VECTOR; SHORT HAIRPIN RNA; ASAP1 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; PROSPERO-RELATED HOMEOBOX 1 PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMALL INTERFERING RNA; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASAP1 GENE; BREAST CELL; BREAST EPITHELIUM CELL; BREAST STEM CELL; CARCINOGENESIS; CELL SURVIVAL; CLONOGENESIS; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; GENE; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEXT GENERATION SEQUENCING; NONHUMAN; PROX1 GENE; RNA INTERFERENCE; RNA SEQUENCE; STEM CELL; ANIMAL; CELL COUNT; CELL DIFFERENTIATION; EPITHELIUM CELL; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETICS; HIGH THROUGHPUT SEQUENCING; IMMUNOPHENOTYPING; METABOLISM; REPRODUCIBILITY; UDDER;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL COUNT; CELL DIFFERENTIATION; EPITHELIAL CELLS; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HOMEODOMAIN PROTEINS; IMMUNOPHENOTYPING; MAMMARY GLANDS, ANIMAL; MICE; REPRODUCIBILITY OF RESULTS; RNA, SMALL INTERFERING; STEM CELLS; TUMOR SUPPRESSOR PROTEINS;

EID: 84927937537     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1187-z     Document Type: Article

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