Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex

Nature Biotechnology

Volumn 32, Issue 10, 2014, Pages 1053-1058

  Pollen, Alex A ^a,b   Nowakowski, Tomasz J ^a,b   Shuga, Joe ^c   Wang, Xiaohui ^c   Leyrat, Anne A ^c   Lui, Jan H ^a,b   Li, Nianzhen ^c   Szpankowski, Lukasz ^c   Fowler, Brian ^c   Chen, Peilin ^c   Ramalingam, Naveen ^c   Sun, Gang ^c   Thu, Myo ^c   Norris, Michael ^c   Lebofsky, Ronald ^c   Toppani, Dominique ^c   Kemp, Darnell W ^c   Wong, Michael ^c   Clerkson, Barry ^c   Jones, Brittnee N ^c   Wu, Shiquan ^c   Knutsson, Lawrence ^c   Alvarado, Beatriz ^c   Wang, Jing ^c   Weaver, Lesley S ^c   May, Andrew P ^c   Jones, Robert C ^c   Unger, Marc A ^c   Kriegstein, Arnold R ^a,b   West, Jay A A ^c   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c FLUIDIGM CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL PROLIFERATION; CELLS; CYTOLOGY; GENE EXPRESSION; MICROFLUIDICS; MOBILE SECURITY;

BIOMARKER IDENTIFICATION; CANDIDATE TARGET; CELL POPULATIONS; HETEROGENEOUS TISSUES; LARGE SCALE SURVEYS; PARALLEL SEQUENCING; SIGNALING PATHWAYS; SINGLE CELL CAPTURES;

CELL SIGNALING;

ASPM PROTEIN; BIOLOGICAL MARKER; CALCIUM; CELL MARKER; CYCLIN DEPENDENT KINASE 1; EARLY GROWTH RESPONSE FACTOR 1; EXCITATORY AMINO ACID TRANSPORTER 1; MESSENGER RNA; NOTCH RECEPTOR; PROTEIN FOS; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTOME; UNCLASSIFIED DRUG; VIMENTIN;

ANIMAL CELL; ARTICLE; BRAIN CELL; BRAIN CORTEX; BRAIN DEVELOPMENT; CELL DIVISION; CELL HETEROGENEITY; CELL MIGRATION; CONTROLLED STUDY; EMBRYO; EXTRACELLULAR CALCIUM; FETUS; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC IDENTIFICATION; GLIA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMEDIATE EARLY GENE; IN SITU HYBRIDIZATION; INTERNEURON; MACROGLIA; MOLECULAR PATHOLOGY; MOUSE; NEUROEPITHELIUM CELL; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NEWBORN; NONHUMAN; PLURIPOTENT STEM CELL; PRIMARY CELL; PRIORITY JOURNAL; RNA SEQUENCE; SINGLE CELL ANALYSIS; STEM CELL NICHE; SUBVENTRICULAR ZONE; WNT SIGNALING PATHWAY; ANIMAL; BIOLOGY; EQUIPMENT DESIGN; GENE EXPRESSION PROFILING; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROFLUIDIC ANALYSIS; PHYSIOLOGY; PROCEDURES; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

ANIMALS; CEREBRAL CORTEX; COMPUTATIONAL BIOLOGY; EQUIPMENT DESIGN; GENE EXPRESSION PROFILING; HUMANS; MICE; MICROFLUIDIC ANALYTICAL TECHNIQUES; RNA, MESSENGER; SEQUENCE ANALYSIS, RNA; SIGNAL TRANSDUCTION;

EID: 84922321862     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.2967     Document Type: Article

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