-
1
-
-
57349148680
-
A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability
-
Eirew P, Stingl J, Raouf A, Turashvili G, Aparicio S, Emerman JT, et al. A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability. Nat Med. 2008;14:1384-9.
-
(2008)
Nat Med.
, vol.14
, pp. 1384-1389
-
-
Eirew, P.1
Stingl, J.2
Raouf, A.3
Turashvili, G.4
Aparicio, S.5
Emerman, J.T.6
-
2
-
-
68349130357
-
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
-
Lim E, Vaillant F, Wu D, Forrest NC, Pal B, Hart AH, et al. Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat Med. 2009;15:907-13.
-
(2009)
Nat Med.
, vol.15
, pp. 907-913
-
-
Lim, E.1
Vaillant, F.2
Wu, D.3
Forrest, N.C.4
Pal, B.5
Hart, A.H.6
-
3
-
-
30144433093
-
Generation of a functional mammary gland from a single stem cell
-
Shackleton M, Vaillant F, Simpson KJ, Stingl J, Smyth GK, Asselin-Labat ML, et al. Generation of a functional mammary gland from a single stem cell. Nature. 2006;439:84-8.
-
(2006)
Nature.
, vol.439
, pp. 84-88
-
-
Shackleton, M.1
Vaillant, F.2
Simpson, K.J.3
Stingl, J.4
Smyth, G.K.5
Asselin-Labat, M.L.6
-
4
-
-
33845982922
-
Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland
-
Sleeman KE, Kendrick H, Robertson D, Isacke CM, Ashworth A, Smalley MJ. Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland. J Cell Biol. 2007;176:19-26.
-
(2007)
J Cell Biol.
, vol.176
, pp. 19-26
-
-
Sleeman, K.E.1
Kendrick, H.2
Robertson, D.3
Isacke, C.M.4
Ashworth, A.5
Smalley, M.J.6
-
5
-
-
30144432901
-
Purification and unique properties of mammary epithelial stem cells
-
Stingl J, Eirew P, Ricketson I, Shackleton M, Vaillant F, Choi D, et al. Purification and unique properties of mammary epithelial stem cells. Nature. 2006;439:993-7.
-
(2006)
Nature.
, vol.439
, pp. 993-997
-
-
Stingl, J.1
Eirew, P.2
Ricketson, I.3
Shackleton, M.4
Vaillant, F.5
Choi, D.6
-
6
-
-
34247117277
-
Evidence for a stem cell hierarchy in the adult human breast
-
Villadsen R, Fridriksdottir AJ, Ronnov-Jessen L, Gudjonsson T, Rank F, LaBarge MA, et al. Evidence for a stem cell hierarchy in the adult human breast. J Cell Biol. 2007;177:87-101.
-
(2007)
J Cell Biol.
, vol.177
, pp. 87-101
-
-
Villadsen, R.1
Fridriksdottir, A.J.2
Ronnov-Jessen, L.3
Gudjonsson, T.4
Rank, F.5
LaBarge, M.A.6
-
7
-
-
33847126689
-
Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation
-
Asselin-Labat ML, Sutherland KD, Barker H, Thomas R, Shackleton M, Forrest NC, et al. Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nat Cell Biol. 2007;9:201-9.
-
(2007)
Nat Cell Biol.
, vol.9
, pp. 201-209
-
-
Asselin-Labat, M.L.1
Sutherland, K.D.2
Barker, H.3
Thomas, R.4
Shackleton, M.5
Forrest, N.C.6
-
8
-
-
83255186736
-
Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14
-
Asselin-Labat ML, Sutherland KD, Vaillant F, Gyorki DE, Wu D, Holroyd S, et al. Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14. Mol Cell Biol. 2011;31:4609-22.
-
(2011)
Mol Cell Biol.
, vol.31
, pp. 4609-4622
-
-
Asselin-Labat, M.L.1
Sutherland, K.D.2
Vaillant, F.3
Gyorki, D.E.4
Wu, D.5
Holroyd, S.6
-
9
-
-
84867639947
-
Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland
-
Shehata M, Teschendorff A, Sharp G, Novcic N, Russell IA, Avril S, et al. Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland. Breast Cancer Res. 2012;14:R134.
-
(2012)
Breast Cancer Res.
, vol.14
, pp. R134
-
-
Shehata, M.1
Teschendorff, A.2
Sharp, G.3
Novcic, N.4
Russell, I.A.5
Avril, S.6
-
10
-
-
84901758365
-
Mammary stem cells and the differentiation hierarchy: current status and perspectives
-
Visvader JE, Stingl J. Mammary stem cells and the differentiation hierarchy: current status and perspectives. Genes Dev. 2014;28:1143-58.
-
(2014)
Genes Dev.
, vol.28
, pp. 1143-1158
-
-
Visvader, J.E.1
Stingl, J.2
-
11
-
-
58949085251
-
Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate
-
Kendrick H, Regan JL, Magnay FA, Grigoriadis A, Mitsopoulos C, Zvelebil M, et al. Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate. BMC Genomics. 2008;9:591.
-
(2008)
BMC Genomics.
, vol.9
, pp. 591
-
-
Kendrick, H.1
Regan, J.L.2
Magnay, F.A.3
Grigoriadis, A.4
Mitsopoulos, C.5
Zvelebil, M.6
-
12
-
-
77955895963
-
Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
-
Lim E, Wu D, Pal B, Bouras T, Asselin-Labat ML, Vaillant F, et al. Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways. Breast Cancer Res. 2010;12:R21.
-
(2010)
Breast Cancer Res.
, vol.12
, pp. R21
-
-
Lim, E.1
Wu, D.2
Pal, B.3
Bouras, T.4
Asselin-Labat, M.L.5
Vaillant, F.6
-
13
-
-
79955631509
-
Epigenetic regulation of cell type-specific expression patterns in the human mammary epithelium
-
Maruyama R, Choudhury S, Kowalczyk A, Bessarabova M, Beresford-Smith B, Conway T, et al. Epigenetic regulation of cell type-specific expression patterns in the human mammary epithelium. PLoS Genet. 2011;7, e1001369.
-
(2011)
PLoS Genet.
, vol.7
-
-
Maruyama, R.1
Choudhury, S.2
Kowalczyk, A.3
Bessarabova, M.4
Beresford-Smith, B.5
Conway, T.6
-
14
-
-
84874231902
-
Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2
-
Pal B, Bouras T, Shi W, Vaillant F, Sheridan JM, Fu N, et al. Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2. Cell Rep. 2013;3:411-26.
-
(2013)
Cell Rep.
, vol.3
, pp. 411-426
-
-
Pal, B.1
Bouras, T.2
Shi, W.3
Vaillant, F.4
Sheridan, J.M.5
Fu, N.6
-
16
-
-
58849163959
-
MicroRNAs: key regulators of stem cells
-
Gangaraju VK, Lin H. MicroRNAs: key regulators of stem cells. Nat Rev Mol Cell Biol. 2009;10:116-25.
-
(2009)
Nat Rev Mol Cell Biol.
, vol.10
, pp. 116-125
-
-
Gangaraju, V.K.1
Lin, H.2
-
17
-
-
84904985459
-
Regulation of microRNA biogenesis
-
Ha M, Kim VN. Regulation of microRNA biogenesis. Nat Rev Mol Cell Biol. 2014;15:509-24.
-
(2014)
Nat Rev Mol Cell Biol.
, vol.15
, pp. 509-524
-
-
Ha, M.1
Kim, V.N.2
-
18
-
-
74049112952
-
Characterisation of microRNA expression in post-natal mouse mammary gland development
-
Avril-Sassen S, Goldstein LD, Stingl J, Blenkiron C, Le Quesne J, Spiteri I, et al. Characterisation of microRNA expression in post-natal mouse mammary gland development. BMC Genomics. 2009;10:548.
-
(2009)
BMC Genomics.
, vol.10
, pp. 548
-
-
Avril-Sassen, S.1
Goldstein, L.D.2
Stingl, J.3
Blenkiron, C.4
Quesne, J.5
Spiteri, I.6
-
19
-
-
37249031072
-
A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells
-
Ibarra I, Erlich Y, Muthuswamy SK, Sachidanandam R, Hannon GJ. A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells. Genes Dev. 2007;21:3238-43.
-
(2007)
Genes Dev.
, vol.21
, pp. 3238-3243
-
-
Ibarra, I.1
Erlich, Y.2
Muthuswamy, S.K.3
Sachidanandam, R.4
Hannon, G.J.5
-
20
-
-
68049114782
-
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
-
Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, Qian D, et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell. 2009;138:592-603.
-
(2009)
Cell.
, vol.138
, pp. 592-603
-
-
Shimono, Y.1
Zabala, M.2
Cho, R.W.3
Lobo, N.4
Dalerba, P.5
Qian, D.6
-
21
-
-
84908139767
-
The STAT5-regulated miR-193b locus restrains mammary stem and progenitor cell activity and alveolar differentiation
-
Yoo KH, Kang K, Feuermann Y, Jang SJ, Robinson GW, Hennighausen L. The STAT5-regulated miR-193b locus restrains mammary stem and progenitor cell activity and alveolar differentiation. Dev Biol. 2014;395:245-54.
-
(2014)
Dev Biol.
, vol.395
, pp. 245-254
-
-
Yoo, K.H.1
Kang, K.2
Feuermann, Y.3
Jang, S.J.4
Robinson, G.W.5
Hennighausen, L.6
-
22
-
-
37548999684
-
Altered microRNA expression confined to specific epithelial cell subpopulations in breast cancer
-
Sempere LF, Christensen M, Silahtaroglu A, Bak M, Heath CV, Schwartz G, et al. Altered microRNA expression confined to specific epithelial cell subpopulations in breast cancer. Cancer Res. 2007;67:11612-20.
-
(2007)
Cancer Res.
, vol.67
, pp. 11612-11620
-
-
Sempere, L.F.1
Christensen, M.2
Silahtaroglu, A.3
Bak, M.4
Heath, C.V.5
Schwartz, G.6
-
23
-
-
37549024511
-
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
-
Blenkiron C, Goldstein LD, Thorne NP, Spiteri I, Chin SF, Dunning MJ, et al. MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol. 2007;8:R214.
-
(2007)
Genome Biol.
, vol.8
, pp. R214
-
-
Blenkiron, C.1
Goldstein, L.D.2
Thorne, N.P.3
Spiteri, I.4
Chin, S.F.5
Dunning, M.J.6
-
24
-
-
84926507971
-
Limma powers differential expression analyses for RNA-sequencing and microarray studies
-
Ritchie ME, Phipson B, Wu D, Hu Y, Law CW, Shi W, et al. Limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 2015;43:e47.
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. e47
-
-
Ritchie, M.E.1
Phipson, B.2
Wu, D.3
Hu, Y.4
Law, C.W.5
Shi, W.6
-
25
-
-
0037316303
-
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
-
Bolstad BM, Irizarry RA, Astrand M, Speed TP. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics. 2003;19:185-93.
-
(2003)
Bioinformatics.
, vol.19
, pp. 185-193
-
-
Bolstad, B.M.1
Irizarry, R.A.2
Astrand, M.3
Speed, T.P.4
-
26
-
-
4544341015
-
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
-
Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol. 2004;3:Article3.
-
(2004)
Stat Appl Genet Mol Biol
, vol.3
, pp. 3
-
-
Smyth, G.K.1
-
27
-
-
0001677717
-
Controlling the false discovery rate: a practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Royal Stat Soc. 1995;Series B 57:289-300.
-
(1995)
J Royal Stat Soc
, vol.Series B 57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
28
-
-
84936788180
-
-
The targetscan
-
The targetscan. http://www.targetscan.org .
-
-
-
-
29
-
-
77955889132
-
ROAST: rotation gene set tests for complex microarray experiments
-
Wu D, Lim E, Vaillant F, Asselin-Labat ML, Visvader JE, Smyth GK. ROAST: rotation gene set tests for complex microarray experiments. Bioinformatics. 2010;26:2176-82.
-
(2010)
Bioinformatics.
, vol.26
, pp. 2176-2182
-
-
Wu, D.1
Lim, E.2
Vaillant, F.3
Asselin-Labat, M.L.4
Visvader, J.E.5
Smyth, G.K.6
-
30
-
-
84936788181
-
-
The TCGA BRCA dataset. https://tcga-data.nci.nih.gov .
-
-
-
-
31
-
-
77953176036
-
A scaling normalization method for differential expression analysis of RNA-seq data
-
Robinson MD, Oshlack A. A scaling normalization method for differential expression analysis of RNA-seq data. Genome Biol. 2010;11:R25.
-
(2010)
Genome Biol.
, vol.11
, pp. R25
-
-
Robinson, M.D.1
Oshlack, A.2
-
32
-
-
84878580738
-
The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote
-
Liao Y, Smyth GK, Shi W. The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote. Nucleic Acids Res. 2013;41, e108.
-
(2013)
Nucleic Acids Res.
, vol.41
-
-
Liao, Y.1
Smyth, G.K.2
Shi, W.3
-
33
-
-
84936788182
-
-
The miRBase database. http://www.mirbase.org .
-
-
-
-
34
-
-
84897397058
-
FeatureCounts: an efficient general purpose program for assigning sequence reads to genomic features
-
Liao Y, Smyth GK, Shi W. FeatureCounts: an efficient general purpose program for assigning sequence reads to genomic features. Bioinformatics. 2014;30:923-30.
-
(2014)
Bioinformatics.
, vol.30
, pp. 923-930
-
-
Liao, Y.1
Smyth, G.K.2
Shi, W.3
-
35
-
-
75249087100
-
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
-
Robinson MD, McCarthy DJ, Smyth GK. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics. 2010;26:139-40.
-
(2010)
Bioinformatics
, vol.26
, pp. 139-140
-
-
Robinson, M.D.1
McCarthy, D.J.2
Smyth, G.K.3
-
36
-
-
84858041341
-
Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation
-
McCarthy DJ, Chen Y, Smyth GK. Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation. Nucleic Acids Res. 2012;40:4288-97.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 4288-4297
-
-
McCarthy, D.J.1
Chen, Y.2
Smyth, G.K.3
-
37
-
-
57649174634
-
MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer
-
Zhao JJ, Lin J, Yang H, Kong W, He L, Ma X, et al. MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer. J Biol Chem. 2008;283:31079-86.
-
(2008)
J Biol Chem.
, vol.283
, pp. 31079-31086
-
-
Zhao, J.J.1
Lin, J.2
Yang, H.3
Kong, W.4
He, L.5
Ma, X.6
-
38
-
-
29144440077
-
MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation
-
Felli N, Fontana L, Pelosi E, Botta R, Bonci D, Facchiano F, et al. MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc Natl Acad Sci U S A. 2005;102:18081-6.
-
(2005)
Proc Natl Acad Sci U S A.
, vol.102
, pp. 18081-18086
-
-
Felli, N.1
Fontana, L.2
Pelosi, E.3
Botta, R.4
Bonci, D.5
Facchiano, F.6
-
39
-
-
84883478160
-
miR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer
-
Cai J, Fang L, Huang Y, Li R, Yuan J, Yang Y, et al. miR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer. Cancer Res. 2013;73:5402-15.
-
(2013)
Cancer Res
, vol.73
, pp. 5402-5415
-
-
Cai, J.1
Fang, L.2
Huang, Y.3
Li, R.4
Yuan, J.5
Yang, Y.6
-
40
-
-
84879672675
-
MicroRNA-205, a novel regulator of the anti-apoptotic protein Bcl2, is downregulated in prostate cancer
-
Verdoodt B, Neid M, Vogt M, Kuhn V, Liffers ST, Palisaar RJ, et al. MicroRNA-205, a novel regulator of the anti-apoptotic protein Bcl2, is downregulated in prostate cancer. Int J Oncol. 2013;43:307-14.
-
(2013)
Int J Oncol.
, vol.43
, pp. 307-314
-
-
Verdoodt, B.1
Neid, M.2
Vogt, M.3
Kuhn, V.4
Liffers, S.T.5
Palisaar, R.J.6
-
41
-
-
84883007415
-
miR-10a restores human mesenchymal stem cell differentiation by repressing KLF4
-
Li J, Dong J, Zhang ZH, Zhang DC, You XY, Zhong Y, et al. miR-10a restores human mesenchymal stem cell differentiation by repressing KLF4. J Cell Physiol. 2013;228:2324-36.
-
(2013)
J Cell Physiol
, vol.228
, pp. 2324-2336
-
-
Li, J.1
Dong, J.2
Zhang, Z.H.3
Zhang, D.C.4
You, X.Y.5
Zhong, Y.6
-
42
-
-
84901044654
-
MicroRNA-10a controls airway smooth muscle cell proliferation via direct targeting of the PI3 kinase pathway
-
Hu R, Pan W, Fedulov AV, Jester W, Jones MR, Weiss ST, et al. MicroRNA-10a controls airway smooth muscle cell proliferation via direct targeting of the PI3 kinase pathway. FASEB J. 2014;28:2347-57.
-
(2014)
FASEB J.
, vol.28
, pp. 2347-2357
-
-
Hu, R.1
Pan, W.2
Fedulov, A.V.3
Jester, W.4
Jones, M.R.5
Weiss, S.T.6
-
43
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol. 2008;10:593-601.
-
(2008)
Nat Cell Biol.
, vol.10
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
-
44
-
-
84896500851
-
microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma
-
Kim J, Zhang Y, Skalski M, Hayes J, Kefas B, Schiff D, et al. microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma. Cancer Res. 2014;74:1541-53.
-
(2014)
Cancer Res
, vol.74
, pp. 1541-1553
-
-
Kim, J.1
Zhang, Y.2
Skalski, M.3
Hayes, J.4
Kefas, B.5
Schiff, D.6
-
45
-
-
77950250954
-
MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta
-
Tsukamoto Y, Nakada C, Noguchi T, Tanigawa M, Nguyen LT, Uchida T, et al. MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta. Cancer Res. 2010;70:2339-49.
-
(2010)
Cancer Res.
, vol.70
, pp. 2339-2349
-
-
Tsukamoto, Y.1
Nakada, C.2
Noguchi, T.3
Tanigawa, M.4
Nguyen, L.T.5
Uchida, T.6
-
46
-
-
84876276472
-
Signaling between transforming growth factor beta (TGF-beta) and transcription factor SNAI2 represses expression of microRNA miR-203 to promote epithelial-mesenchymal transition and tumor metastasis
-
Ding X, Park SI, McCauley LK, Wang CY. Signaling between transforming growth factor beta (TGF-beta) and transcription factor SNAI2 represses expression of microRNA miR-203 to promote epithelial-mesenchymal transition and tumor metastasis. J Biol Chem. 2013;288:10241-53.
-
(2013)
J Biol Chem.
, vol.288
, pp. 10241-10253
-
-
Ding, X.1
Park, S.I.2
McCauley, L.K.3
Wang, C.Y.4
-
47
-
-
40749111551
-
A skin microRNA promotes differentiation by repressing 'stemness'
-
Yi R, Poy MN, Stoffel M, Fuchs E. A skin microRNA promotes differentiation by repressing 'stemness'. Nature. 2008;452:225-9.
-
(2008)
Nature.
, vol.452
, pp. 225-229
-
-
Yi, R.1
Poy, M.N.2
Stoffel, M.3
Fuchs, E.4
-
48
-
-
84859121913
-
Epigenetic silencing of miR-203 upregulates SNAI2 and contributes to the invasiveness of malignant breast cancer cells
-
Zhang Z, Zhang B, Li W, Fu L, Fu L, Zhu Z, et al. Epigenetic silencing of miR-203 upregulates SNAI2 and contributes to the invasiveness of malignant breast cancer cells. Genes Cancer. 2011;2:782-91.
-
(2011)
Genes Cancer.
, vol.2
, pp. 782-791
-
-
Zhang, Z.1
Zhang, B.2
Li, W.3
Fu, L.4
Fu, L.5
Zhu, Z.6
-
49
-
-
48449091318
-
Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence
-
Laurent LC, Chen J, Ulitsky I, Mueller FJ, Lu C, Shamir R, et al. Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence. Stem Cells. 2008;26:1506-16.
-
(2008)
Stem Cells.
, vol.26
, pp. 1506-1516
-
-
Laurent, L.C.1
Chen, J.2
Ulitsky, I.3
Mueller, F.J.4
Lu, C.5
Shamir, R.6
-
51
-
-
84925969713
-
EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival
-
Fu NY, Rios AC, Pal B, Soetanto R, Lun ATL, Liu K, et al. EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival. Nature Cell Biol. 2015;17:365-75.
-
(2015)
Nature Cell Biol.
, vol.17
, pp. 365-375
-
-
Fu, N.Y.1
Rios, A.C.2
Pal, B.3
Soetanto, R.4
Lun, A.T.L.5
Liu, K.6
-
52
-
-
77958487607
-
Computational identification and characterization of primate-specific microRNAs in human genome
-
Lin S, Cheung WK, Chen S, Lu G, Wang Z, Xie D, et al. Computational identification and characterization of primate-specific microRNAs in human genome. Comput Biol Chem. 2010;34:232-41.
-
(2010)
Comput Biol Chem.
, vol.34
, pp. 232-241
-
-
Lin, S.1
Cheung, W.K.2
Chen, S.3
Lu, G.4
Wang, Z.5
Xie, D.6
-
53
-
-
84860395749
-
A novel oncogenic role for the miRNA-506-514 cluster in initiating melanocyte transformation and promoting melanoma growth
-
Streicher KL, Zhu W, Lehmann KP, Georgantas RW, Morehouse CA, Brohawn P, et al. A novel oncogenic role for the miRNA-506-514 cluster in initiating melanocyte transformation and promoting melanoma growth. Oncogene. 2012;31:1558-70.
-
(2012)
Oncogene.
, vol.31
, pp. 1558-1570
-
-
Streicher, K.L.1
Zhu, W.2
Lehmann, K.P.3
Georgantas, R.W.4
Morehouse, C.A.5
Brohawn, P.6
-
54
-
-
84872847361
-
The genomic landscape of breast cancer as a therapeutic roadmap
-
Ellis MJ, Perou CM. The genomic landscape of breast cancer as a therapeutic roadmap. Cancer Discov. 2013;3:27-34.
-
(2013)
Cancer Discov.
, vol.3
, pp. 27-34
-
-
Ellis, M.J.1
Perou, C.M.2
-
55
-
-
79952049614
-
miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors
-
e16915.
-
Enerly E, Steinfeld I, Kleivi K, Leivonen SK, Aure MR, Russnes HG, et al. miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors. PLoS One. 2011;6, e16915.
-
(2011)
PLoS One
, vol.6
-
-
Enerly, E.1
Steinfeld, I.2
Kleivi, K.3
Leivonen, S.K.4
Aure, M.R.5
Russnes, H.G.6
-
56
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Cancer Genome Atlas N. Comprehensive molecular portraits of human breast tumours. Nature. 2012;490:61-70.
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
-
57
-
-
79960565215
-
Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis
-
Zaragosi LE, Wdziekonski B, Brigand KL, Villageois P, Mari B, Waldmann R, et al. Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis. Genome Biol. 2011;12:R64.
-
(2011)
Genome Biol.
, vol.12
, pp. R64
-
-
Zaragosi, L.E.1
Wdziekonski, B.2
Brigand, K.L.3
Villageois, P.4
Mari, B.5
Waldmann, R.6
-
58
-
-
84905401527
-
MicroRNA-148a suppresses the epithelial-mesenchymal transition and metastasis of hepatoma cells by targeting Met/Snail signaling
-
Zhang JP, Zeng C, Xu L, Gong J, Fang JH, Zhuang SM. MicroRNA-148a suppresses the epithelial-mesenchymal transition and metastasis of hepatoma cells by targeting Met/Snail signaling. Oncogene. 2014;33:4069-76.
-
(2014)
Oncogene.
, vol.33
, pp. 4069-4076
-
-
Zhang, J.P.1
Zeng, C.2
Xu, L.3
Gong, J.4
Fang, J.H.5
Zhuang, S.M.6
-
59
-
-
84898869604
-
The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland
-
Llobet-Navas D, Rodriguez-Barrueco R, Castro V, Ugalde AP, Sumazin P, Jacob-Sendler D, et al. The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland. Genes Dev. 2014;28:765-82.
-
(2014)
Genes Dev.
, vol.28
, pp. 765-782
-
-
Llobet-Navas, D.1
Rodriguez-Barrueco, R.2
Castro, V.3
Ugalde, A.P.4
Sumazin, P.5
Jacob-Sendler, D.6
-
60
-
-
45449097073
-
miR-203 represses 'stemness' by repressing DeltaNp63
-
Lena AM, Shalom-Feuerstein R, Rivetti di Val Cervo P, Aberdam D, Knight RA, Melino G, et al. miR-203 represses 'stemness' by repressing DeltaNp63. Cell Death Differ. 2008;15:1187-95.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1187-1195
-
-
Lena, A.M.1
Shalom-Feuerstein, R.2
Rivetti di Val Cervo, P.3
Aberdam, D.4
Knight, R.A.5
Melino, G.6
-
61
-
-
84877263242
-
A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells
-
Bu P, Chen KY, Chen JH, Wang L, Walters J, Shin YJ, et al. A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells. Cell Stem Cell. 2013;12:602-15.
-
(2013)
Cell Stem Cell.
, vol.12
, pp. 602-615
-
-
Bu, P.1
Chen, K.Y.2
Chen, J.H.3
Wang, L.4
Walters, J.5
Shin, Y.J.6
-
62
-
-
79751473114
-
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
-
Liu C, Kelnar K, Liu B, Chen X, Calhoun-Davis T, Li H, et al. The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med. 2011;17:211-5.
-
(2011)
Nat Med.
, vol.17
, pp. 211-215
-
-
Liu, C.1
Kelnar, K.2
Liu, B.3
Chen, X.4
Calhoun-Davis, T.5
Li, H.6
-
63
-
-
52949134150
-
Notch signaling regulates mammary stem cell function and luminal cell-fate commitment
-
Bouras T, Pal B, Vaillant F, Harburg G, Asselin-Labat ML, Oakes SR, et al. Notch signaling regulates mammary stem cell function and luminal cell-fate commitment. Cell Stem Cell. 2008;3:429-41.
-
(2008)
Cell Stem Cell.
, vol.3
, pp. 429-441
-
-
Bouras, T.1
Pal, B.2
Vaillant, F.3
Harburg, G.4
Asselin-Labat, M.L.5
Oakes, S.R.6
-
64
-
-
47049090497
-
Bmi1 regulates stem cells and proliferation and differentiation of committed cells in mammary epithelium
-
Pietersen AM, Evers B, Prasad AA, Tanger E, Cornelissen-Steijger P, Jonkers J, et al. Bmi1 regulates stem cells and proliferation and differentiation of committed cells in mammary epithelium. Curr Biol. 2008;18:1094-9.
-
(2008)
Curr Biol.
, vol.18
, pp. 1094-1099
-
-
Pietersen, A.M.1
Evers, B.2
Prasad, A.A.3
Tanger, E.4
Cornelissen-Steijger, P.5
Jonkers, J.6
-
65
-
-
77956628008
-
Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture
-
Zeng YA, Nusse R. Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture. Cell Stem Cell. 2010;6:568-77.
-
(2010)
Cell Stem Cell.
, vol.6
, pp. 568-577
-
-
Zeng, Y.A.1
Nusse, R.2
-
66
-
-
77956164185
-
The primate-specific microRNA gene cluster (C19MC) is imprinted in the placenta
-
Noguer-Dance M, Abu-Amero S, Al-Khtib M, Lefevre A, Coullin P, Moore GE, et al. The primate-specific microRNA gene cluster (C19MC) is imprinted in the placenta. Hum Mol Genet. 2010;19:3566-82.
-
(2010)
Hum Mol Genet.
, vol.19
, pp. 3566-3582
-
-
Noguer-Dance, M.1
Abu-Amero, S.2
Al-Khtib, M.3
Lefevre, A.4
Coullin, P.5
Moore, G.E.6
-
67
-
-
84879863078
-
Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state
-
Lim YY, Wright JA, Attema JL, Gregory PA, Bert AG, Smith E, et al. Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state. J Cell Sci. 2013;126:2256-66.
-
(2013)
J Cell Sci.
, vol.126
, pp. 2256-2266
-
-
Lim, Y.Y.1
Wright, J.A.2
Attema, J.L.3
Gregory, P.A.4
Bert, A.G.5
Smith, E.6
-
68
-
-
33847763576
-
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells
-
Lujambio A, Ropero S, Ballestar E, Fraga MF, Cerrato C, Setien F, et al. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res. 2007;67:1424-9.
-
(2007)
Cancer Res.
, vol.67
, pp. 1424-1429
-
-
Lujambio, A.1
Ropero, S.2
Ballestar, E.3
Fraga, M.F.4
Cerrato, C.5
Setien, F.6
-
69
-
-
80052195502
-
Genome-wide profiling of chromatin signatures reveals epigenetic regulation of microRNA genes in colorectal cancer
-
Suzuki H, Takatsuka S, Akashi H, Yamamoto E, Nojima M, Maruyama R, et al. Genome-wide profiling of chromatin signatures reveals epigenetic regulation of microRNA genes in colorectal cancer. Cancer Res. 2011;71:5646-58.
-
(2011)
Cancer Res.
, vol.71
, pp. 5646-5658
-
-
Suzuki, H.1
Takatsuka, S.2
Akashi, H.3
Yamamoto, E.4
Nojima, M.5
Maruyama, R.6
-
70
-
-
78649787634
-
Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect
-
Suzuki H, Yamamoto E, Nojima M, Kai M, Yamano HO, Yoshikawa K, et al. Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect. Carcinogenesis. 2010;31:2066-73.
-
(2010)
Carcinogenesis.
, vol.31
, pp. 2066-2073
-
-
Suzuki, H.1
Yamamoto, E.2
Nojima, M.3
Kai, M.4
Yamano, H.O.5
Yoshikawa, K.6
-
71
-
-
49249121155
-
Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
-
Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y, et al. Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res. 2008;68:4123-32.
-
(2008)
Cancer Res.
, vol.68
, pp. 4123-4132
-
-
Toyota, M.1
Suzuki, H.2
Sasaki, Y.3
Maruyama, R.4
Imai, K.5
Shinomura, Y.6
-
74
-
-
69949189728
-
MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer
-
Lowery AJ, Miller N, Devaney A, McNeill RE, Davoren PA, Lemetre C, et al. MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer. Breast Cancer Res. 2009;11:R27.
-
(2009)
Breast Cancer Res.
, vol.11
, pp. R27
-
-
Lowery, A.J.1
Miller, N.2
Devaney, A.3
McNeill, R.E.4
Davoren, P.A.5
Lemetre, C.6
-
75
-
-
84898441297
-
A microRNA signature associated with early recurrence in breast cancer
-
Perez-Rivas LG, Jerez JM, Carmona R, de Luque V, Vicioso L, Claros MG, et al. A microRNA signature associated with early recurrence in breast cancer. PLoS One. 2014;9, e91884.
-
(2014)
PLoS One.
, vol.9
-
-
Perez-Rivas, L.G.1
Jerez, J.M.2
Carmona, R.3
Luque, V.4
Vicioso, L.5
Claros, M.G.6
-
76
-
-
33748624597
-
Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies
-
Mattie MD, Benz CC, Bowers J, Sensinger K, Wong L, Scott GK, et al. Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies. Mol Cancer. 2006;5:24.
-
(2006)
Mol Cancer.
, vol.5
, pp. 24
-
-
Mattie, M.D.1
Benz, C.C.2
Bowers, J.3
Sensinger, K.4
Wong, L.5
Scott, G.K.6
-
77
-
-
23844555119
-
MicroRNA gene expression deregulation in human breast cancer
-
Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 2005;65:7065-70.
-
(2005)
Cancer Res.
, vol.65
, pp. 7065-7070
-
-
Iorio, M.V.1
Ferracin, M.2
Liu, C.G.3
Veronese, A.4
Spizzo, R.5
Sabbioni, S.6
-
78
-
-
54049084380
-
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
-
Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, Shannon MF, et al. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res. 2008;68:7846-54.
-
(2008)
Cancer Res.
, vol.68
, pp. 7846-7854
-
-
Bracken, C.P.1
Gregory, P.A.2
Kolesnikoff, N.3
Bert, A.G.4
Wang, J.5
Shannon, M.F.6
-
79
-
-
84949320826
-
Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential
-
Knezevic J, Pfefferle AD, Petrovic I, Greene SB, Perou CM, Rosen JM. Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential. Oncogene. 2015. doi: 10.1038/onc.2015.48 .
-
(2015)
Oncogene
-
-
Knezevic, J.1
Pfefferle, A.D.2
Petrovic, I.3
Greene, S.B.4
Perou, C.M.5
Rosen, J.M.6
-
80
-
-
84918554912
-
MicroRNA100 inhibits self-renewal of breast cancer stem-like cells and breast tumor development
-
Deng L, Shang L, Bai S, Chen J, He X, Martin-Trevino R, et al. MicroRNA100 inhibits self-renewal of breast cancer stem-like cells and breast tumor development. Cancer Res. 2014;74:6648-60.
-
(2014)
Cancer Res.
, vol.74
, pp. 6648-6660
-
-
Deng, L.1
Shang, L.2
Bai, S.3
Chen, J.4
He, X.5
Martin-Trevino, R.6
-
81
-
-
84879177004
-
MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11
-
Bockhorn J, Dalton R, Nwachukwu C, Huang S, Prat A, Yee K, et al. MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11. Nat Commun. 2013;4:1393.
-
(2013)
Nat Commun.
, vol.4
, pp. 1393
-
-
Bockhorn, J.1
Dalton, R.2
Nwachukwu, C.3
Huang, S.4
Prat, A.5
Yee, K.6
|