Transcriptome analysis of the normal human mammary cell commitment and differentiation process

Cell Stem Cell

Volumn 3, Issue 1, 2008, Pages 109-118

  Raouf, Afshin ^a   Zhao, Yun ^a   To, Karen ^a   Stingl, John ^a,e   Delaney, Allen ^b   Barbara, Mary ^c   Iscove, Norman ^c   Jones, Steven ^b   McKinney, Steven ^b   Emerman, Joanne ^d   Aparicio, Samuel ^b   Marra, Marco ^b,d   Eaves, Connie ^a,d  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b BRITISH COLUMBIA CANCER AGENCY   (Canada)

^c PRINCESS MARGARET HOSPITAL   (Canada)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^e CANCER RESEARCH UK CAMBRIDGE RESEARCH INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LEUKOCYTE ANTIGEN; NOTCH RECEPTOR;

ARTICLE; BREAST; CELL DIFFERENTIATION; CYTOLOGY; EPITHELIUM CELL; FEMALE; GENE EXPRESSION PROFILING; GENETICS; HUMAN; PHYSIOLOGY; PREGNANCY; REFERENCE VALUE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEM CELL;

ANTIGENS, CD; BREAST; CELL DIFFERENTIATION; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; PREGNANCY; RECEPTORS, NOTCH; REFERENCE VALUES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 48649096223     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2008.05.018     Document Type: Article

References (50)

1. Al-Hajj, M., Wicha, M.S., Benito-Hernandez, A., Morrison, S.J., and Clarke, M.F. (2003). Prospective identification of tumorigenic breast cancer cells. Proc. Natl. Acad. Sci. USA 100, 3983-3988. (Pubitemid 36418143)
2. Allenspach, E.J., Maillard, I., Aster, J.C., and Pear, W.S. (2002). Notch signaling in cancer. Cancer Biol. Ther. 1, 466-476.
3. Asselin-Labat, M.L., Shackleton, M., Stingl, J., Vaillant, F., Forrest, N.C., Eaves, C.J., Visvader, J.E., and Lindeman, G.J. (2006). Steroid hormone receptor status of mouse mammary stem cells. J. Natl. Cancer Inst. 98, 1011-1014. (Pubitemid 44288166)
4. Asselin-Labat, M.L., Sutherland, K.D., Barker, H., Thomas, R., Shackleton, M., Forrest, N.C., Hartley, L., Robb, L., Grosveld, F.G., van der Wees, J., et al. (2007). Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nat. Cell Biol. 9, 201-209. (Pubitemid 46420863)
5. Balazs, A.B., Fabian, A.J., Esmon, C.T., and Mulligan, R.C. (2006). Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow. Blood 107, 2317-2321. (Pubitemid 43345550)
6. Bigas, A., Martin, D.I., and Milner, L.A. (1998). Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines. Mol. Cell. Biol. 18, 2324-2333. (Pubitemid 28152679)
7. Blanpain, C., Lowry, W.E., Geoghegan, A., Polak, L., and Fuchs, E. (2004). Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 118, 635-648. (Pubitemid 39179715)
8. Bruneau, B.G., Bao, Z.Z., Fatkin, D., Xavier-Neto, J., Georgakopoulos, D., Maguire, C.T., Berul, C.I., Kass, D.A., Kuroski-de Bold, M.L., de Bold, A.J., et al. (2001). Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression. Mol. Cell. Biol. 21, 1730-1736. (Pubitemid 32156393)
9. Buono, K.D., Robinson, G.W., Martin, C., Shi, S., Stanley, P., Tanigaki, K., Honjo, T., and Hennighausen, L. (2006). The canonical Notch/RBP-J signaling pathway controls the balance of cell lineages in mammary epithelium during pregnancy. Dev. Biol. 293, 565-580.
10. Callahan, R., and Egan, S.E. (2004). Notch signaling in mammary development and oncogenesis. J. Mammary Gland Biol. Neoplasia 9, 145-163. (Pubitemid 39177500)
11. Dontu, G., Abdallah, W.M., Foley, J.M., Jackson, K.W., Clarke, M.F., Kawamura, M.J., and Wicha, M.S. (2003). In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev. 17, 1253-1270. (Pubitemid 36583168)
12. Dontu, G., Jackson, K.W., McNicholas, E., Kawamura, M.J., Abdallah, W.M., and Wicha, M.S. (2004). Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells. Breast Cancer Res. 6, R605-R615.
13. Eisen, M.B., Spellman, P.T., Brown, P.O., and Botstein, D. (1998). Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. USA 95, 14863-14868. (Pubitemid 29003722)
14. Farnie, G., Clarke, R.B., Spence, K., Pinnock, N., Brennan, K., Anderson, N.G., and Bundred, N.J. (2007). Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways. J. Natl. Cancer Inst. 99, 616-627. (Pubitemid 47073543)
15. Fuchs, E., and Raghavan, S. (2002). Getting under the skin of epidermal morphogenesis. Nat. Rev. Genet. 3, 199-209. (Pubitemid 34506588)
16. Gentleman, R.C., Carey, V.J., Bates, D.M., Bolstad, B., Dettling, M., Dudoit, S., Ellis, B., Gautier, L., Ge, Y., Gentry, J., et al. (2004). Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 5, R80.
17. Ginestier, C., Hur, M.H., Charafe-Jauffret, E., Monville, F., Dutcher, J., Brown, M., Jacquemier, J., Viens, P., Kleer, C.G., Liu, S., et al. (2007). ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1, 555-567. (Pubitemid 350056407)
18. Howlin, J., McBryan, J., and Martin, F. (2006). Pubertal mammary gland development: insights from mouse models. J. Mammary Gland Biol. Neoplasia 11, 283-297. (Pubitemid 44869922)
19. Hu, Y., Sun, H., Drake, J., Kittrell, F., Abba, M.C., Deng, L., Gaddis, S., Sahin, A., Baggerly, K., Medina, D., and Aldaz, C.M. (2004). From mice to humans: identification of commonly deregulated genes in mammary cancer via comparative SAGE studies. Cancer Res. 64, 7748-7755. (Pubitemid 39446906)
20. Hu, Z., Fan, C., Oh, D.S., Marron, J.S., He, X., Qaqish, B.F., Livasy, C., Carey, L.A., Reynolds, E., Dressler, L., et al. (2006). The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genomics 7, 96.
21. Imren, S., Fabry, M.E., Westerman, K.A., Pawliuk, R., Tang, P., Rosten, P.M., Nagel, R.L., Leboulch, P., Eaves, C.J., and Humphries, R.K. (2004). High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells. J. Clin. Invest. 114, 953-962. (Pubitemid 39578723)
22. Ince, T.A., Richardson, A.L., Bell, G.W., Saitoh, M., Godar, S., Karnoub, A.E., Iglehart, J.D., and Weinberg, R.A. (2007). Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes. Cancer Cell 12, 160-170. (Pubitemid 47199120)
23. Iscove, N.N., Barbara, M., Gu, M., Gibson, M., Modi, C., and Winegarden, N. (2002). Representation is faithfully preserved in global cDNA amplified exponentially from sub-picogram quantities of mRNA. Nat. Biotechnol. 20, 940-943. (Pubitemid 35001134)
24. Jones, C., Mackay, A., Grigoriadis, A., Cossu, A., Reis-Filho, J.S., Fulford, L., Dexter, T., Davies, S., Bulmer, K., Ford, E., et al. (2004). Expression profiling of purified normal human luminal and myoepithelial breast cells: identification of novel prognostic markers for breast cancer. Cancer Res. 64, 3037-3045. (Pubitemid 38581402)
25. Kordon, E.C., and Smith, G.H. (1998). An entire functional mammary gland may comprise the progeny from a single cell. Development 125, 1921-1930. (Pubitemid 28274378)
26. Kritikou, E.A., Sharkey, A., Abell, K., Came, P.J., Anderson, E., Clarkson, R.W., and Watson, C.J. (2003). A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland. Development 130, 3459-3468. (Pubitemid 37010009)
27. Leong, K.G., Niessen, K., Kulic, I., Raouf, A., Eaves, C., Pollet, I., and Karsan, A. (2007). Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. J. Exp. Med. 204, 2935-2948. (Pubitemid 350179562)
28. Lewis, M.T., Ross, S., Strickland, P.A., Snyder, C.J., and Daniel, C.W. (1999). Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast. Cell Tissue Res. 296, 549-554. (Pubitemid 29253686)
29. Liu, S., Ginestier, C., Charafe-Jauffret, E., Foco, H., Kleer, C.G., Merajver, S.D., Dontu, G., and Wicha, M.S. (2008). BRCA1 regulates human mammary stem/ progenitor cell fate. Proc. Natl. Acad. Sci. USA 105, 1680-1685. (Pubitemid 351346574)
30. Maillard, I., Weng, A.P., Carpenter, A.C., Rodriguez, C.G., Sai, H., Xu, L., Allman, D., Aster, J.C., and Pear, W.S. (2004). Mastermind critically regulates Notch-mediated lymphoid cell fate decisions. Blood 104, 1696-1702. (Pubitemid 39202276)
31. Osborne, B.A., and Minter, L.M. (2007). Notch signalling during peripheral T-cell activation and differentiation. Nat. Rev. Immunol. 7, 64-75. (Pubitemid 46020828)
32. Pece, S., Serresi, M., Santolini, E., Capra, M., Hulleman, E., Galimberti, V., Zurrida, S., Maisonneuve, P., Viale, G., and Di Fiore, P.P. (2004). Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis. J. Cell Biol. 167, 215-221. (Pubitemid 39435065)
33. Raafat, A., Bargo, S., Anver, M.R., and Callahan, R. (2004). Mammary development and tumorigenesis in mice expressing a truncated human Notch4/Int3 intracellular domain (h-Int3sh). Oncogene 23, 9401-9407. (Pubitemid 40069672)
34. Robertson, N., Oveisi-Fordorei, M., Zuyderduyn, S.D., Varhol, R.J., Fjell, C., Marra, M., Jones, S., and Siddiqui, A. (2007). DiscoverySpace: an interactive data analysis application. Genome Biol. 8, R6.
35. Russo, J., and Russo, I.H. (2004). Development of the human breast. Maturitas 49, 2-15. (Pubitemid 39209366)
36. Saha, S., Sparks, A.B., Rago, C., Akmaev, V., Wang, C.J., Vogelstein, B., Kinzler, K.W., and Velculescu, V.E. (2002). Using the transcriptome to annotate the genome. Nat. Biotechnol. 20, 508-512. (Pubitemid 34495940)
37. Shackleton, M., Vaillant, F., Simpson, K.J., Stingl, J., Smyth, G.K., Asselin-Labat, M.L., Wu, L., Lindeman, G.J., and Visvader, J.E. (2006). Generation of a functional mammary gland from a single stem cell. Nature 439, 84-88. (Pubitemid 43053633)
38. Shi, W., and Harris, A.L. (2006). Notch signaling in breast cancer and tumor angiogenesis: cross-talk and therapeutic potentials. J. Mammary Gland Biol. Neoplasia 11, 41-52. (Pubitemid 44309188)
39. Smalley, M.J., Titley, J., Paterson, H., Perusinghe, N., Clarke, C., and O'Hare, M.J. (1999). Differentiation of separated mouse mammary luminal epithelial and myoepithelial cells cultured on EHS matrix analyzed by indirect immunofluorescence of cytoskeletal antigens. J. Histochem. Cytochem. 47, 1513-1524.
40. Stingl, J., Eaves, C.J., Kuusk, U., and Emerman, J.T. (1998). Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast. Differentiation 63, 201-213. (Pubitemid 28428734)
41. Stingl, J., Eaves, C.J., Zandieh, I., and Emerman, J.T. (2001). Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue. Breast Cancer Res. Treat. 67, 93-109. (Pubitemid 32744490)
42. Stingl, J., Raouf, A., Emerman, J.T., and Eaves, C.J. (2005). Epithelial progenitors in the normal human mammary gland. J. Mammary Gland Biol. Neoplasia 10, 49-59. (Pubitemid 40724022)
43. Stingl, J., Eirew, P., Ricketson, I., Shackleton, M., Vaillant, F., Choi, D., Li, H.I., and Eaves, C.J. (2006a). Purification and unique properties of mammary epithelial stem cells. Nature 439, 993-997. (Pubitemid 43292419)
44. Stingl, J., Raouf, A., Eirew, P., and Eaves, C.J. (2006b). Deciphering the mammary epithelial cell hierarchy. Cell Cycle 5, 1519-1522. (Pubitemid 44091971)
45. Tietjen, I., Rihel, J.M., Cao, Y., Koentges, G., Zakhary, L., and Dulac, C. (2003). Single-cell transcriptional analysis of neuronal progenitors. Neuron 38, 161-175. (Pubitemid 36555644)
46. Tsai, Y.C., Lu, Y., Nichols, P.W., Zlotnikov, G., Jones, P.A., and Smith, H.S. (1996). Contiguous patches of normal human mammary epithelium derived from a single stem cell: implications for breast carcinogenesis. Cancer Res. 56, 402-404. (Pubitemid 26026371)
47. van Tuyl, M., Liu, J., Groenman, F., Ridsdale, R., Han, R.N., Venkatesh, V., Tibboel, D., and Post, M. (2006). Iroquois genes influence proximo-distal morphogenesis during rat lung development. Am. J. Physiol. Lung Cell. Mol. Physiol. 290, L777-L789. (Pubitemid 43725084)
48. Welm, B.E., Tepera, S.B., Venezia, T., Graubert, T.A., Rosen, J.M., and Goodell, M.A. (2002). Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev. Biol. 245, 42-56. (Pubitemid 34461802)
49. Weng, A.P., Nam, Y., Wolfe, M.S., Pear, W.S., Griffin, J.D., Blacklow, S.C., and Aster, J.C. (2003). Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling. Mol. Cell. Biol. 23, 655-664. (Pubitemid 36050558)
50. Zhao, Y., Raouf, A., Kent, D., Khattra, J., Delaney, A., Schnerch, A., Asano, J., McDonald, H., Chan, C., Jones, S., et al. (2007). A modified polymerase chain reaction-long serial analysis of gene expression protocol identifies novel transcripts in human CD34+ bone marrow cells. Stem Cells 25, 1681-1689. (Pubitemid 47121845)