Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation

Journal of Biological Chemistry

Volumn 286, Issue 3, 2011, Pages 2273-2284

  Snider, Natasha T ^a   Weerasinghe, Sujith V W ^a   Iñiguez Lluhí, Jorge A ^a   Herrmann, Harald ^b   Omary, M Bishr ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; CONFORMATIONAL CHANGE; CYTOSKELETONS; EPITHELIAL CELLS; FILAMENT DYNAMICS; HEPATOCYTES; HEPATOPROTECTION; HETERODIMERIZATION; HUMAN LIVER; IN-CELL; IN-VITRO; INTERMEDIATE FILAMENTS; LIVER DISEASE; MOUSE LIVER; PHOSPHORYLATION SITES; SITE-SPECIFIC; STRESS-INDUCED PROTEINS; SUMOYLATION; TISSUE INJURY; VIMENTIN; WILD TYPES;

CELL DEATH; LIVER; SOLUBILITY;

PHOSPHORYLATION;

CYTOKERATIN 18; CYTOKERATIN 19; CYTOKERATIN 8; KERATIN; LYSINE; PHOSPHATASE; VIMENTIN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL STRESS; CONTROLLED STUDY; DIMERIZATION; ENZYME INHIBITION; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INTERMEDIATE FILAMENT; LIVER DISEASE; MALE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SUMOYLATION; UBIQUITINATION;

ANIMALS; BIOLOGICAL MARKERS; HUMANS; KERATINS; LIVER; LIVER DISEASES; MALE; MICE; MICE, TRANSGENIC; MUTATION; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; SUMOYLATION; UBIQUITINS;

EID: 78751534200     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.171314     Document Type: Article

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