메뉴 건너뛰기




Volumn 9, Issue 4, 2013, Pages

Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against Toxoplasma gondii

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN ATG5; GAMMA INTERFERON; GUANINE NUCLEOTIDE BINDING PROTEIN; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; VIRULENCE FACTOR; VIRULENCE FACTOR ROP 18;

EID: 84876857964     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003320     Document Type: Article
Times cited : (152)

References (52)
  • 2
    • 0347091255 scopus 로고    scopus 로고
    • Recent expansion of Toxoplasma through enhanced oral transmission
    • Su C, Evans D, Cole RH, Kissinger JC, Ajioka JW, et al. (2003) Recent expansion of Toxoplasma through enhanced oral transmission. Science 299: 414-416.
    • (2003) Science , vol.299 , pp. 414-416
    • Su, C.1    Evans, D.2    Cole, R.H.3    Kissinger, J.C.4    Ajioka, J.W.5
  • 4
    • 0035881198 scopus 로고    scopus 로고
    • Toxoplasma gondii infection in the United States: seroprevalence and risk factors
    • Jones JL, Kruszon-Moran D, Wilson M, McQuillan G, Navin T, et al. (2001) Toxoplasma gondii infection in the United States: seroprevalence and risk factors. Am J Epidemiol 154: 357-365.
    • (2001) Am J Epidemiol , vol.154 , pp. 357-365
    • Jones, J.L.1    Kruszon-Moran, D.2    Wilson, M.3    McQuillan, G.4    Navin, T.5
  • 5
    • 53849092760 scopus 로고    scopus 로고
    • Population structure of Toxoplasma gondii: Clonal expansion driven by infrequent recombination and selective sweeps
    • Sibley LD, Ajioka JW, (2008) Population structure of Toxoplasma gondii: Clonal expansion driven by infrequent recombination and selective sweeps. Ann Rev Microbiol 62: 329-351.
    • (2008) Ann Rev Microbiol , vol.62 , pp. 329-351
    • Sibley, L.D.1    Ajioka, J.W.2
  • 6
    • 68549109625 scopus 로고    scopus 로고
    • Forward genetics in Toxoplasma gondii reveals a family of rhoptry kinases that mediates pathogenesis
    • Sibley LD, Qiu W, Fentress S, Taylor SJ, Khan A, et al. (2009) Forward genetics in Toxoplasma gondii reveals a family of rhoptry kinases that mediates pathogenesis. Eukaryot Cell 8: 1085-1093.
    • (2009) Eukaryot Cell , vol.8 , pp. 1085-1093
    • Sibley, L.D.1    Qiu, W.2    Fentress, S.3    Taylor, S.J.4    Khan, A.5
  • 7
    • 33845706251 scopus 로고    scopus 로고
    • Polymorphic secreted kinases are key virulence factors in toxoplasmosis
    • Saeij JPJ, Boyle JP, Coller S, Taylor S, Sibley LD, et al. (2006) Polymorphic secreted kinases are key virulence factors in toxoplasmosis. Science 314: 1780-1783.
    • (2006) Science , vol.314 , pp. 1780-1783
    • Saeij, J.P.J.1    Boyle, J.P.2    Coller, S.3    Taylor, S.4    Sibley, L.D.5
  • 8
    • 33845705275 scopus 로고    scopus 로고
    • A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii
    • Taylor S, Barragan A, Su C, Fux B, Fentress SJ, et al. (2006) A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii. Science 314: 1776-1780.
    • (2006) Science , vol.314 , pp. 1776-1780
    • Taylor, S.1    Barragan, A.2    Su, C.3    Fux, B.4    Fentress, S.J.5
  • 9
    • 84870848874 scopus 로고    scopus 로고
    • The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18
    • Behnke MS, Fentress SJ, Mashayekhi M, Li LL, Taylor GA, et al. (2012) The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18. PLoS Path 8: e1002992.
    • (2012) PLoS Path , vol.8
    • Behnke, M.S.1    Fentress, S.J.2    Mashayekhi, M.3    Li, L.L.4    Taylor, G.A.5
  • 11
    • 0027264849 scopus 로고
    • Interleukin 12 is required for the T-lymphocyte-independent induction of interferon γ by an intracellular parasite and induces resistance in T-cell-deficient mice
    • Gazzinelli RT, Heiny S, Wynn TA, Wolf S, Sher A, (1993) Interleukin 12 is required for the T-lymphocyte-independent induction of interferon γ by an intracellular parasite and induces resistance in T-cell-deficient mice. Proc Nat Acad Sci (USA) 90: 6115-6119.
    • (1993) Proc Nat Acad Sci (USA) , vol.90 , pp. 6115-6119
    • Gazzinelli, R.T.1    Heiny, S.2    Wynn, T.A.3    Wolf, S.4    Sher, A.5
  • 12
    • 0023895411 scopus 로고
    • Interferon-γ: the major mediator of resistance against Toxoplasma gondii
    • Suzuki Y, Orellana MA, Schreiber RD, Remington JS, (1988) Interferon-γ: the major mediator of resistance against Toxoplasma gondii. Science 240: 516-518.
    • (1988) Science , vol.240 , pp. 516-518
    • Suzuki, Y.1    Orellana, M.A.2    Schreiber, R.D.3    Remington, J.S.4
  • 13
    • 0033526013 scopus 로고    scopus 로고
    • Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-gamma- and tumor necrosis factor (TNF)-alpha- dependent host resistance to the intracellular pathogen, Toxoplasma gondii
    • Yap GS, Sher A, (1999) Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-gamma- and tumor necrosis factor (TNF)-alpha- dependent host resistance to the intracellular pathogen, Toxoplasma gondii. J Exp Med 189: 1083-1091.
    • (1999) J Exp Med , vol.189 , pp. 1083-1091
    • Yap, G.S.1    Sher, A.2
  • 14
    • 80051792857 scopus 로고    scopus 로고
    • The IRG protein-based resistance mechanism in mice and its relation to virulence in Toxoplasma gondii
    • Howard JC, Hunn JP, Steinfeldt T, (2011) The IRG protein-based resistance mechanism in mice and its relation to virulence in Toxoplasma gondii. Curr Opin Microbiol 14: 414-421.
    • (2011) Curr Opin Microbiol , vol.14 , pp. 414-421
    • Howard, J.C.1    Hunn, J.P.2    Steinfeldt, T.3
  • 16
    • 0035898464 scopus 로고    scopus 로고
    • Inactivation of LRG-47 and IRG-47 reveals a family of interferon γ-inducible genes with essential, pathogen-specific roles in resistance to infection
    • Collazo CM, Yap GS, Sempowski GD, Lusby KC, Tessarollo L, et al. (2001) Inactivation of LRG-47 and IRG-47 reveals a family of interferon γ-inducible genes with essential, pathogen-specific roles in resistance to infection. J Exp Med 194: 181-188.
    • (2001) J Exp Med , vol.194 , pp. 181-188
    • Collazo, C.M.1    Yap, G.S.2    Sempowski, G.D.3    Lusby, K.C.4    Tessarollo, L.5
  • 17
    • 0034681123 scopus 로고    scopus 로고
    • Pathogen-specific loss of host resistance in mice lacking IFN-γ-inducible gene IGTP
    • Taylor GA, Collazo CM, Yap GS, Nguyen K, Gregorio TA, et al. (2000) Pathogen-specific loss of host resistance in mice lacking IFN-γ-inducible gene IGTP. Proc Nat Acad Sci 97: 751-755.
    • (2000) Proc Nat Acad Sci , vol.97 , pp. 751-755
    • Taylor, G.A.1    Collazo, C.M.2    Yap, G.S.3    Nguyen, K.4    Gregorio, T.A.5
  • 18
    • 33748444233 scopus 로고    scopus 로고
    • Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages
    • Ling YM, Shaw MH, Ayala C, Coppens I, Taylor GA, et al. (2006) Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages. J Exp Med 203: 2063-2071.
    • (2006) J Exp Med , vol.203 , pp. 2063-2071
    • Ling, Y.M.1    Shaw, M.H.2    Ayala, C.3    Coppens, I.4    Taylor, G.A.5
  • 19
    • 49649126253 scopus 로고    scopus 로고
    • Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases
    • Martens S, Parvanova I, Zerrahn J, Griffiths G, Schell G, et al. (2005) Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases. Plos Pathogens 1: e24.
    • (2005) Plos Pathogens , vol.1
    • Martens, S.1    Parvanova, I.2    Zerrahn, J.3    Griffiths, G.4    Schell, G.5
  • 20
    • 61449117883 scopus 로고    scopus 로고
    • Disruption of the Toxoplasma gondii parasitophorous vacuole by IFN-gamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death
    • Zhao YO, Khaminets A, Hunn JP, Howard JC, (2009) Disruption of the Toxoplasma gondii parasitophorous vacuole by IFN-gamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death. PLoS Pathog 5: e1000288.
    • (2009) PLoS Pathog , vol.5
    • Zhao, Y.O.1    Khaminets, A.2    Hunn, J.P.3    Howard, J.C.4
  • 21
    • 53549109432 scopus 로고    scopus 로고
    • Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii
    • Hunn JP, Koenen-Waisman S, Papic N, Schroeder N, Pawlowski N, et al. (2008) Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii. EMBO J 27: 2495-2509.
    • (2008) EMBO J , vol.27 , pp. 2495-2509
    • Hunn, J.P.1    Koenen-Waisman, S.2    Papic, N.3    Schroeder, N.4    Pawlowski, N.5
  • 22
    • 77954430293 scopus 로고    scopus 로고
    • Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole
    • Khaminets A, Hunn JP, Konen-Waisman S, Zhao YO, Preukschat D, et al. (2010) Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole. Cell Microbiol 12: 939-961.
    • (2010) Cell Microbiol , vol.12 , pp. 939-961
    • Khaminets, A.1    Hunn, J.P.2    Konen-Waisman, S.3    Zhao, Y.O.4    Preukschat, D.5
  • 23
    • 55249109400 scopus 로고    scopus 로고
    • Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens
    • Zhao Z, Fux B, Goodwin M, Dunay IR, Strong D, et al. (2008) Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens. Cell Host Microbe 4: 458-469.
    • (2008) Cell Host Microbe , vol.4 , pp. 458-469
    • Zhao, Z.1    Fux, B.2    Goodwin, M.3    Dunay, I.R.4    Strong, D.5
  • 24
    • 78650194774 scopus 로고    scopus 로고
    • Phosphorylation of immunity-related GTPases by a parasite secretory kinase promotes macrophage survival and virulence
    • Fentress SJ, Behnke MS, Dunay IR, Moashayekhi M, Rommereim LM, et al. (2010) Phosphorylation of immunity-related GTPases by a parasite secretory kinase promotes macrophage survival and virulence. Cell Host Microbe 16: 484-495.
    • (2010) Cell Host Microbe , vol.16 , pp. 484-495
    • Fentress, S.J.1    Behnke, M.S.2    Dunay, I.R.3    Moashayekhi, M.4    Rommereim, L.M.5
  • 25
    • 78650210471 scopus 로고    scopus 로고
    • Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii
    • Steinfeldt T, Konen-Waisman S, Tong L, Pawlowski N, Lamkemeyer T, et al. (2010) Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii. PLoS Biol 8: e1000576.
    • (2010) PLoS Biol , vol.8
    • Steinfeldt, T.1    Konen-Waisman, S.2    Tong, L.3    Pawlowski, N.4    Lamkemeyer, T.5
  • 26
    • 84860258296 scopus 로고    scopus 로고
    • Interferon-inducible effector mechanisms in cell-autonomous immunity
    • MacMicking JD, (2012) Interferon-inducible effector mechanisms in cell-autonomous immunity. Nat Rev Immunol 12: 367-382.
    • (2012) Nat Rev Immunol , vol.12 , pp. 367-382
    • MacMicking, J.D.1
  • 28
    • 79955777383 scopus 로고    scopus 로고
    • A family of IFN-gamma-inducible 65-kD GTPases protects against bacterial infection
    • Kim BH, Shenoy AR, Kumar P, Das R, Tiwari S, et al. (2011) A family of IFN-gamma-inducible 65-kD GTPases protects against bacterial infection. Science 332: 717-721.
    • (2011) Science , vol.332 , pp. 717-721
    • Kim, B.H.1    Shenoy, A.R.2    Kumar, P.3    Das, R.4    Tiwari, S.5
  • 29
    • 44149120744 scopus 로고    scopus 로고
    • Analyses of murine GBP homology clusters based on in silico, in vitro and in vivo studies
    • Kresse A, Konermann C, Degrandi D, Beuter-Gunia C, Wuerthner J, et al. (2008) Analyses of murine GBP homology clusters based on in silico, in vitro and in vivo studies. BMC Genomics 9: 158.
    • (2008) BMC Genomics , vol.9 , pp. 158
    • Kresse, A.1    Konermann, C.2    Degrandi, D.3    Beuter-Gunia, C.4    Wuerthner, J.5
  • 30
    • 38849193453 scopus 로고    scopus 로고
    • Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense
    • Degrandi D, Konermann C, Beuter-Gunia C, Kresse A, Wurthner J, et al. (2007) Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense. J Immunology 179: 7729-7740.
    • (2007) J Immunology , vol.179 , pp. 7729-7740
    • Degrandi, D.1    Konermann, C.2    Beuter-Gunia, C.3    Kresse, A.4    Wurthner, J.5
  • 31
    • 80052549593 scopus 로고    scopus 로고
    • Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it
    • Virreira Winter S, Niedelman W, Jensen KD, Rosowski EE, Julien L, et al. (2011) Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it. PLoS One 6: e24434.
    • (2011) PLoS One , vol.6
    • Virreira Winter, S.1    Niedelman, W.2    Jensen, K.D.3    Rosowski, E.E.4    Julien, L.5
  • 32
    • 84865371084 scopus 로고    scopus 로고
    • A cluster of Interferon-gamma-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii
    • Yamamoto M, Okuyama M, Ma JS, Kimura T, Kamiyama N, et al. (2012) A cluster of Interferon-gamma-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii. Immunity 37: 302-313.
    • (2012) Immunity , vol.37 , pp. 302-313
    • Yamamoto, M.1    Okuyama, M.2    Ma, J.S.3    Kimura, T.4    Kamiyama, N.5
  • 33
    • 84860225554 scopus 로고    scopus 로고
    • GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals
    • Shenoy AR, Wellington DA, Kumar P, Kassa H, Booth CJ, et al. (2012) GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals. Science 336: 481-485.
    • (2012) Science , vol.336 , pp. 481-485
    • Shenoy, A.R.1    Wellington, D.A.2    Kumar, P.3    Kassa, H.4    Booth, C.J.5
  • 35
    • 79959348595 scopus 로고    scopus 로고
    • Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseuodokinases
    • Behnke MS, Khan A, Wootton JC, Dubey JP, Tang K, et al. (2011) Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseuodokinases. Proc Natl Acad Sci (USA) 108: 9631-9636.
    • (2011) Proc Natl Acad Sci (USA) , vol.108 , pp. 9631-9636
    • Behnke, M.S.1    Khan, A.2    Wootton, J.C.3    Dubey, J.P.4    Tang, K.5
  • 36
    • 80052235117 scopus 로고    scopus 로고
    • Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy
    • Traver MK, Henry SC, Cantillana V, Oliver T, Hunn JP, et al. (2011) Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy. J Biol Chem 286: 30471-30480.
    • (2011) J Biol Chem , vol.286 , pp. 30471-30480
    • Traver, M.K.1    Henry, S.C.2    Cantillana, V.3    Oliver, T.4    Hunn, J.P.5
  • 37
    • 0030970867 scopus 로고    scopus 로고
    • Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii
    • Scharton-Kersten TM, Yap G, Magram J, Sher A, (1997) Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii. Journal of Experimental Medicine 185: 1261-1273.
    • (1997) Journal of Experimental Medicine , vol.185 , pp. 1261-1273
    • Scharton-Kersten, T.M.1    Yap, G.2    Magram, J.3    Sher, A.4
  • 39
    • 84864075588 scopus 로고    scopus 로고
    • The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response
    • Niedelman W, Gold DA, Rosowski EE, Sprokholt JK, Lim D, et al. (2012) The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response. PLoS Pathog 8: e1002784.
    • (2012) PLoS Pathog , vol.8
    • Niedelman, W.1    Gold, D.A.2    Rosowski, E.E.3    Sprokholt, J.K.4    Lim, D.5
  • 40
    • 84864989434 scopus 로고    scopus 로고
    • The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii
    • Kravets E, Degrandi D, Weidtkamp-Peters S, Ries B, Konermann C, et al. (2012) The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii. J Biol Chem 287: 27452-27466.
    • (2012) J Biol Chem , vol.287 , pp. 27452-27466
    • Kravets, E.1    Degrandi, D.2    Weidtkamp-Peters, S.3    Ries, B.4    Konermann, C.5
  • 41
    • 79959228478 scopus 로고    scopus 로고
    • The IFN-gamma-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens
    • Liesenfeld O, Parvanova I, Zerrahn J, Han SJ, Heinrich F, et al. (2011) The IFN-gamma-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens. PLoS One 6: e20568.
    • (2011) PLoS One , vol.6
    • Liesenfeld, O.1    Parvanova, I.2    Zerrahn, J.3    Han, S.J.4    Heinrich, F.5
  • 42
    • 67649376348 scopus 로고    scopus 로고
    • The evolutionarily dynamic IFN-inducible GTPase proteins play conserved immune functions in vertebrates and cephalochordates
    • Li G, Zhang J, Sun Y, Wang H, Wang Y, (2009) The evolutionarily dynamic IFN-inducible GTPase proteins play conserved immune functions in vertebrates and cephalochordates. Mol Biol Evol 26: 1619-1630.
    • (2009) Mol Biol Evol , vol.26 , pp. 1619-1630
    • Li, G.1    Zhang, J.2    Sun, Y.3    Wang, H.4    Wang, Y.5
  • 43
    • 0033616531 scopus 로고    scopus 로고
    • Interferon-induced guanylate binding protein-1 (GBP-1) mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus
    • Anderson SL, Carton JM, Lou J, Xing L, Rubin BY, (1999) Interferon-induced guanylate binding protein-1 (GBP-1) mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus. Virology 256: 8-14.
    • (1999) Virology , vol.256 , pp. 8-14
    • Anderson, S.L.1    Carton, J.M.2    Lou, J.3    Xing, L.4    Rubin, B.Y.5
  • 44
    • 73149122965 scopus 로고    scopus 로고
    • Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein
    • Itsui Y, Sakamoto N, Kakinuma S, Nakagawa M, Sekine-Osajima Y, et al. (2009) Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein. Hepatology 50: 1727-1737.
    • (2009) Hepatology , vol.50 , pp. 1727-1737
    • Itsui, Y.1    Sakamoto, N.2    Kakinuma, S.3    Nakagawa, M.4    Sekine-Osajima, Y.5
  • 45
    • 84857732857 scopus 로고    scopus 로고
    • A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication
    • Nordmann A, Wixler L, Boergeling Y, Wixler V, Ludwig S, (2012) A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication. FASEB J 26: 1290-1300.
    • (2012) FASEB J , vol.26 , pp. 1290-1300
    • Nordmann, A.1    Wixler, L.2    Boergeling, Y.3    Wixler, V.4    Ludwig, S.5
  • 46
    • 68349127168 scopus 로고    scopus 로고
    • Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma
    • Tietzel I, El-Haibi C, Carabeo RA, (2009) Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma. PLoS One 4: e6499.
    • (2009) PLoS One , vol.4
    • Tietzel, I.1    El-Haibi, C.2    Carabeo, R.A.3
  • 47
    • 64749102772 scopus 로고    scopus 로고
    • Tagging of endogenous genes in a Toxoplasma gondii strain lacking Ku80
    • Huynh MH, Carruthers VB, (2009) Tagging of endogenous genes in a Toxoplasma gondii strain lacking Ku80. Eukaryot Cell 8: 530-539.
    • (2009) Eukaryot Cell , vol.8 , pp. 530-539
    • Huynh, M.H.1    Carruthers, V.B.2
  • 48
    • 34248229691 scopus 로고    scopus 로고
    • Toxoplasma gondii: inconsistent dissemination patterns following oral infection in mice
    • Boyle JP, Saeij JP, Boothroyd JC, (2007) Toxoplasma gondii: inconsistent dissemination patterns following oral infection in mice. Exp Parasitol 116: 302-305.
    • (2007) Exp Parasitol , vol.116 , pp. 302-305
    • Boyle, J.P.1    Saeij, J.P.2    Boothroyd, J.C.3
  • 49
    • 0036679131 scopus 로고    scopus 로고
    • Identification of quantitative trait loci controlling acute virulence in Toxoplasma gondii
    • Su C, Howe DK, Dubey JP, Ajioka JW, Sibley LD, (2002) Identification of quantitative trait loci controlling acute virulence in Toxoplasma gondii. Proc Natl Acad Sci (USA) 99: 10753-10758.
    • (2002) Proc Natl Acad Sci (USA) , vol.99 , pp. 10753-10758
    • Su, C.1    Howe, D.K.2    Dubey, J.P.3    Ajioka, J.W.4    Sibley, L.D.5
  • 50
    • 0025121505 scopus 로고
    • Toxoplasma gondii: characterization and localization of antigens secreted from tachyzoites
    • Charif H, Darcy F, Torpier G, Cesbron-Delauw MF, Capron A, (1990) Toxoplasma gondii: characterization and localization of antigens secreted from tachyzoites. Exp Parasitol 71: 114-124.
    • (1990) Exp Parasitol , vol.71 , pp. 114-124
    • Charif, H.1    Darcy, F.2    Torpier, G.3    Cesbron-Delauw, M.F.4    Capron, A.5
  • 51
    • 57349192061 scopus 로고    scopus 로고
    • The Toxoplasma gondii dense granule protein GRA7 is phosphorylated upon invasion and forms an unexpected association with the rhoptry proteins ROP2 and ROP4
    • Dunn JD, Ravindran S, Kim SK, Boothroyd JC, (2008) The Toxoplasma gondii dense granule protein GRA7 is phosphorylated upon invasion and forms an unexpected association with the rhoptry proteins ROP2 and ROP4. Infect Immun 76: 5853-5861.
    • (2008) Infect Immun , vol.76 , pp. 5853-5861
    • Dunn, J.D.1    Ravindran, S.2    Kim, S.K.3    Boothroyd, J.C.4
  • 52


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.