RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense

Journal of Experimental Medicine

Volumn 214, Issue 11, 2017, Pages 3171-3182

  Peterson, Lance W ^a,b   Philip, Naomi H ^a,b,f   DeLaney, Alexandra ^a,b   Wynosky Dolfi, Meghan A ^a,b   Asklof, Kendra ^a   Gray, Falon ^a   Choa, Ruth ^a,b   Bjanes, Elisabet ^a,b   Buza, Elisabeth L ^a   Hu, Baofeng ^a   Dillon, Christopher P ^c   Green, Douglas R ^c   Berger, Scott B ^d   Gough, Peter J ^d   Bertin, John ^e   Brodsky, Igor E ^a,b  

^a UNIVERSITY OF PENNSYLVANIA SCHOOL OF VETERINARY MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d Infectious Disease Therapy Area Unit   (United States)

^e GLAXOSMITHKLINE   (United States)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; RECEPTOR INTERACTING PROTEIN KINASE 1; UNCLASSIFIED DRUG; CYTOKINE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIAL LOAD; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; ENZYME ACTIVITY; GRANULOMA; IMMUNITY; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; YERSINIA; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; DISEASE RESISTANCE; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; KNOCKOUT MOUSE; MACROPHAGE; MAPK SIGNALING; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; SURVIVAL ANALYSIS; YERSINIA PSEUDOTUBERCULOSIS; YERSINIA PSEUDOTUBERCULOSIS INFECTION;

ANIMALS; APOPTOSIS; CYTOKINES; DISEASE RESISTANCE; HOST-PATHOGEN INTERACTIONS; IMMUNITY, INNATE; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, IMMUNOLOGICAL; NF-KAPPA B; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; YERSINIA PSEUDOTUBERCULOSIS; YERSINIA PSEUDOTUBERCULOSIS INFECTIONS;

EID: 85033395440     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20170347     Document Type: Article

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