-
1
-
-
84892833777
-
Discovery and saturation analysisof cancer genes across 21 tumour types
-
Lawrence MS, Stojanov P, Mermel CH, Robinson JT, Garraway LA, Golub TR, Meyerson M, Gabriel SB, Lander ES, Getz G. Discovery and saturation analysisof cancer genes across 21 tumour types. Nature.2014; 505:495-501. https://doi.org/10.1038/nature12912
-
(2014)
Nature
, vol.505
, pp. 495-501
-
-
Lawrence, M.S.1
Stojanov, P.2
Mermel, C.H.3
Robinson, J.T.4
Garraway, L.A.5
Golub, T.R.6
Meyerson, M.7
Gabriel, S.B.8
Lander, E.S.9
Getz, G.10
-
2
-
-
30344478870
-
A global map of p53 transcription-factor binding sites in the human genome
-
Wei CL, Wu Q, Vega VB, Chiu KP, Ng P, Zhang T, Shahab A, Yong HC, Fu Y, Weng Z, Liu J, Zhao XD, Chew JL, et al. A global map of p53 transcription-factor binding sites in the human genome. Cell.2006; 124:207-19. https://doi.org/10.1016/j.cell.2005.10.043
-
(2006)
Cell
, vol.124
, pp. 207-219
-
-
Wei, C.L.1
Wu, Q.2
Vega, V.B.3
Chiu, K.P.4
Ng, P.5
Zhang, T.6
Shahab, A.7
Yong, H.C.8
Fu, Y.9
Weng, Z.10
Liu, J.11
Zhao, X.D.12
Chew, J.L.13
-
3
-
-
84862777719
-
Distinctregulatory mechanisms and functions for p53-activated and p53-repressed DNA damage responsegenes in embryonic stem cells
-
Li M, He Y, Dubois W, Wu X, Shi J, Huang J. Distinctregulatory mechanisms and functions for p53-activated and p53-repressed DNA damage responsegenes in embryonic stem cells. Mol Cell. 2012;46:30-42.https://doi.org/10.1016/j.molcel.2012.01.020
-
(2012)
Mol Cell
, vol.46
, pp. 30-42
-
-
Li, M.1
He, Y.2
Dubois, W.3
Wu, X.4
Shi, J.5
Huang, J.6
-
4
-
-
84926387317
-
Ferroptosis as a p53-mediated activityduring tumour suppression
-
Jiang L, Kon N, Li T, Wang SJ, Su T, Hibshoosh H, BaerR, Gu W. Ferroptosis as a p53-mediated activityduring tumour suppression. Nature. 2015; 520:57-62.https://doi.org/10.1038/nature14344
-
(2015)
Nature
, vol.520
, pp. 57-62
-
-
Jiang, L.1
Kon, N.2
Li, T.3
Wang, S.J.4
Su, T.5
Hibshoosh, H.6
Baer, R.7
Gu, W.8
-
5
-
-
84982845282
-
Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle generegulatory networks
-
Fischer M, Grossmann P, Padi M, DeCaprio JA.Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle generegulatory networks. Nucleic Acids Res. 2016;44:6070-86. https://doi.org/10.1093/nar/gkw523
-
(2016)
Nucleic Acids Res
, vol.44
, pp. 6070-6086
-
-
Fischer, M.1
Grossmann, P.2
Padi, M.3
DeCaprio, J.A.4
-
6
-
-
79955795151
-
Distinct p53transcriptional programs dictate acute DNA-damageresponses and tumor suppression
-
Brady CA, Jiang D, Mello SS, Johnson TM, Jarvis LA, Kozak MM, Kenzelmann Broz D, Basak S, Park EJ, McLaughlin ME, Karnezis AN, Attardi LD. Distinct p53transcriptional programs dictate acute DNA-damageresponses and tumor suppression. Cell. 2011;145:571-83. https://doi.org/10.1016/j.cell.2011.03.035
-
(2011)
Cell
, vol.145
, pp. 571-583
-
-
Brady, C.A.1
Jiang, D.2
Mello, S.S.3
Johnson, T.M.4
Jarvis, L.A.5
Kozak, M.M.6
Kenzelmann Broz, D.7
Basak, S.8
Park, E.J.9
McLaughlin, M.E.10
Karnezis, A.N.11
Attardi, L.D.12
-
7
-
-
84949309449
-
Combined loss of PUMA and p21 acceleratesc-MYC-driven lymphoma development considerablyless than loss of one allele of p53
-
Valente LJ, Grabow S, Vandenberg CJ, Strasser A, Janic A. Combined loss of PUMA and p21 acceleratesc-MYC-driven lymphoma development considerablyless than loss of one allele of p53. Oncogene. 2016;35:3866-71. https://doi.org/10.1038/onc.2015.457
-
(2016)
Oncogene
, vol.35
, pp. 3866-3871
-
-
Valente, L.J.1
Grabow, S.2
Vandenberg, C.J.3
Strasser, A.4
Janic, A.5
-
8
-
-
84926378825
-
Phenotype specific analyses revealdistinct regulatory mechanism for chronicallyactivated p53
-
Kirschner K, Samarajiwa SA, Cairns JM, Menon S, Pérez-Mancera PA, Tomimatsu K, Bermejo-RodriguezC, Ito Y, Chandra T, Narita M, Lyons SK, Lynch AG, Kimura H, et al. Phenotype specific analyses revealdistinct regulatory mechanism for chronicallyactivated p53. PLoS Genet. 2015; 11:e1005053.https://doi.org/10.1371/journal.pgen.1005053
-
(2015)
PLoS Genet
, vol.11
-
-
Kirschner, K.1
Samarajiwa, S.A.2
Cairns, J.M.3
Menon, S.4
Pérez-Mancera, P.A.5
Tomimatsu, K.6
Bermejo-Rodriguez, C.7
Ito, Y.8
Chandra, T.9
Narita, M.10
Lyons, S.K.11
Lynch, A.G.12
Kimura, H.13
-
9
-
-
0032508504
-
Enhanced phosphorylation of p53 by ATM inresponse to DNA damage
-
Banin S, Moyal L, Shieh S, Taya Y, Anderson CW, Chessa L, Smorodinsky NI, Prives C, Reiss Y, Shiloh Y, Ziv Y. Enhanced phosphorylation of p53 by ATM inresponse to DNA damage. Science. 1998; 281:1674-77.https://doi.org/10.1126/science.281.5383.1674
-
(1998)
Science
, vol.281
, pp. 1674-1677
-
-
Banin, S.1
Moyal, L.2
Shieh, S.3
Taya, Y.4
Anderson, C.W.5
Chessa, L.6
Smorodinsky, N.I.7
Prives, C.8
Reiss, Y.9
Shiloh, Y.10
Ziv, Y.11
-
10
-
-
0032530486
-
DNA damageactivates p53 through a phosphorylation-acetylationcascade
-
Sakaguchi K, Herrera JE, Saito S, Miki T, Bustin M, Vassilev A, Anderson CW, Appella E. DNA damageactivates p53 through a phosphorylation-acetylationcascade. Genes Dev. 1998; 12:2831-41.https://doi.org/10.1101/gad.12.18.2831
-
(1998)
Genes Dev
, vol.12
, pp. 2831-2841
-
-
Sakaguchi, K.1
Herrera, J.E.2
Saito, S.3
Miki, T.4
Bustin, M.5
Vassilev, A.6
Anderson, C.W.7
Appella, E.8
-
11
-
-
0032549704
-
The Ink4atumor suppressor gene product, p19Arf, interactswith MDM2 and neutralizes MDM2's inhibition ofp53
-
Pomerantz J, Schreiber-Agus N, Liégeois NJ, Silverman A, Alland L, Chin L, Potes J, Chen K, OrlowI, Lee HW, Cordon-Cardo C, DePinho RA. The Ink4atumor suppressor gene product, p19Arf, interactswith MDM2 and neutralizes MDM2's inhibition ofp53. Cell. 1998; 92:713-23. https://doi.org/10.1016/S0092-8674(00)81400-2
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liégeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.W.10
Cordon-Cardo, C.11
DePinho, R.A.12
-
12
-
-
3242726103
-
PML regulates p53 stabilityby sequestering Mdm2 to the nucleolus
-
Bernardi R, Scaglioni PP, Bergmann S, Horn HF, Vousden KH, Pandolfi PP. PML regulates p53 stabilityby sequestering Mdm2 to the nucleolus. Nat CellBiol. 2004; 6:665-72. https://doi.org/10.1038/ncb1147
-
(2004)
Nat CellBiol
, vol.6
, pp. 665-672
-
-
Bernardi, R.1
Scaglioni, P.P.2
Bergmann, S.3
Horn, H.F.4
Vousden, K.H.5
Pandolfi, P.P.6
-
13
-
-
84892443134
-
5Sribosomal RNA is an essential component of anascent ribosomal precursor complex that regulatesthe Hdm2-p53 checkpoint
-
Donati G, Peddigari S, Mercer CA, Thomas G. 5Sribosomal RNA is an essential component of anascent ribosomal precursor complex that regulatesthe Hdm2-p53 checkpoint. Cell Reports. 2013; 4:87-98.https://doi.org/10.1016/j.celrep.2013.05.045
-
(2013)
Cell Reports
, vol.4
, pp. 87-98
-
-
Donati, G.1
Peddigari, S.2
Mercer, C.A.3
Thomas, G.4
-
14
-
-
71149089592
-
SOCS1 links cytokine signaling to p53and senescence
-
Calabrese V, Mallette FA, Deschênes-Simard X, Ramanathan S, Gagnon J, Moores A, Ilangumaran S, Ferbeyre G. SOCS1 links cytokine signaling to p53and senescence. Mol Cell. 2009; 36:754-67.https://doi.org/10.1016/j.molcel.2009.09.044
-
(2009)
Mol Cell
, vol.36
, pp. 754-767
-
-
Calabrese, V.1
Mallette, F.A.2
Deschênes-Simard, X.3
Ramanathan, S.4
Gagnon, J.5
Moores, A.6
Ilangumaran, S.7
Ferbeyre, G.8
-
15
-
-
79952111177
-
SOCS1, a novel interaction partner of p53 controllingoncogene-induced senescence
-
Mallette FA, Calabrese V, Ilangumaran S, Ferbeyre G.SOCS1, a novel interaction partner of p53 controllingoncogene-induced senescence. Aging (Albany NY).2010; 2:445-52. https://doi.org/10.18632/aging.100163
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 445-452
-
-
Mallette, F.A.1
Calabrese, V.2
Ilangumaran, S.3
Ferbeyre, G.4
-
16
-
-
0035042611
-
SOCS-1, a negative regulator of the JAK/STATpathway, is silenced by methylation in humanhepatocellular carcinoma and shows growth-suppression activity
-
Yoshikawa H, Matsubara K, Qian GS, Jackson P, Groopman JD, Manning JE, Harris CC, Herman JG.SOCS-1, a negative regulator of the JAK/STATpathway, is silenced by methylation in humanhepatocellular carcinoma and shows growth-suppression activity. Nat Genet. 2001; 28:29-35.https://doi.org/10.1038/ng0501-29
-
(2001)
Nat Genet
, vol.28
, pp. 29-35
-
-
Yoshikawa, H.1
Matsubara, K.2
Qian, G.S.3
Jackson, P.4
Groopman, J.D.5
Manning, J.E.6
Harris, C.C.7
Herman, J.G.8
-
17
-
-
84895779578
-
Drugging the p53pathway: understanding the route to clinicalefficacy
-
Khoo KH, Verma CS, Lane DP. Drugging the p53pathway: understanding the route to clinicalefficacy. Nat Rev Drug Discov. 2014; 13:217-36.https://doi.org/10.1038/nrd4288
-
(2014)
Nat Rev Drug Discov
, vol.13
, pp. 217-236
-
-
Khoo, K.H.1
Verma, C.S.2
Lane, D.P.3
-
18
-
-
3843066731
-
BRCA1-BARD1 complexesare required for p53Ser-15 phosphorylation and aG1/S arrest following ionizing radiation-induced DNAdamage
-
Fabbro M, Savage K, Hobson K, Deans AJ, Powell SN, McArthur GA, Khanna KK. BRCA1-BARD1 complexesare required for p53Ser-15 phosphorylation and aG1/S arrest following ionizing radiation-induced DNAdamage. J Biol Chem. 2004; 279:31251-58.https://doi.org/10.1074/jbc.M405372200
-
(2004)
J Biol Chem
, vol.279
, pp. 31251-31258
-
-
Fabbro, M.1
Savage, K.2
Hobson, K.3
Deans, A.J.4
Powell, S.N.5
McArthur, G.A.6
Khanna, K.K.7
-
19
-
-
33947265274
-
Insulin-like growth factor-binding protein-3 inhibition of prostate cancergrowth involves suppression of angiogenesis
-
Liu B, Lee KW, Anzo M, Zhang B, Zi X, Tao Y, Shiry L, Pollak M, Lin S, Cohen P. Insulin-like growth factor-binding protein-3 inhibition of prostate cancergrowth involves suppression of angiogenesis.Oncogene. 2007; 26:1811-19. https://doi.org/10.1038/sj.onc.1209977
-
(2007)
Oncogene
, vol.26
, pp. 1811-1819
-
-
Liu, B.1
Lee, K.W.2
Anzo, M.3
Zhang, B.4
Zi, X.5
Tao, Y.6
Shiry, L.7
Pollak, M.8
Lin, S.9
Cohen, P.10
-
20
-
-
20144374161
-
Canstatin acts on endothelial and tumor cells viamitochondrial damage initiated through interactionwith alphavbeta3 and alphavbeta5 integrins
-
Magnon C, Galaup A, Mullan B, Rouffiac V, BouquetC, Bidart JM, Griscelli F, Opolon P, Perricaudet M.Canstatin acts on endothelial and tumor cells viamitochondrial damage initiated through interactionwith alphavbeta3 and alphavbeta5 integrins. CancerRes. 2005; 65:4353-61. https://doi.org/10.1158/0008-5472.CAN-04-3536
-
(2005)
CancerRes
, vol.65
, pp. 4353-4361
-
-
Magnon, C.1
Galaup, A.2
Mullan, B.3
Rouffiac, V.4
Bouquet, C.5
Bidart, J.M.6
Griscelli, F.7
Opolon, P.8
Perricaudet, M.9
-
21
-
-
0033749398
-
The antiangiogenicagent TNP-470 requires p53 and p21CIP/WAF forendothelial cell growth arrest
-
Yeh JR, Mohan R, Crews CM. The antiangiogenicagent TNP-470 requires p53 and p21CIP/WAF forendothelial cell growth arrest. Proc Natl Acad SciUSA. 2000; 97:12782-87. https://doi.org/10.1073/pnas.97.23.12782
-
(2000)
Proc Natl Acad SciUSA
, vol.97
, pp. 12782-12787
-
-
Yeh, J.R.1
Mohan, R.2
Crews, C.M.3
-
22
-
-
84863277602
-
p53 inhibits angiogenesis byinducing the production of Arresten
-
Assadian S, El-Assaad W, Wang XQ, Gannon PO, Barrès V, Latour M, Mes-Masson AM, Saad F, Sado Y, Dostie J, Teodoro JG. p53 inhibits angiogenesis byinducing the production of Arresten. Cancer Res.2012; 72:1270-79. https://doi.org/10.1158/0008-5472.CAN-11-2348
-
(2012)
Cancer Res
, vol.72
, pp. 1270-1279
-
-
Assadian, S.1
El-Assaad, W.2
Wang, X.Q.3
Gannon, P.O.4
Barrès, V.5
Latour, M.6
Mes-Masson, A.M.7
Saad, F.8
Sado, Y.9
Dostie, J.10
Teodoro, J.G.11
-
23
-
-
84995452435
-
Oxidized arachidonic andadrenic PEs navigate cells to ferroptosis
-
Kagan VE, Mao G, Qu F, Angeli JP, Doll S, Croix CS, Dar HH, Liu B, Tyurin VA, Ritov VB, Kapralov AA, Amoscato AA, Jiang J, et al. Oxidized arachidonic andadrenic PEs navigate cells to ferroptosis. Nat ChemBiol. 2017; 13:81-90. https://doi.org/10.1038/nchembio.2238
-
(2017)
Nat ChemBiol
, vol.13
, pp. 81-90
-
-
Kagan, V.E.1
Mao, G.2
Qu, F.3
Angeli, J.P.4
Doll, S.5
Croix, C.S.6
Dar, H.H.7
Liu, B.8
Tyurin, V.A.9
Ritov, V.B.10
Kapralov, A.A.11
Amoscato, A.A.12
Jiang, J.13
-
24
-
-
84994059408
-
Activation of SAT1engages polyamine metabolism with p53-mediatedferroptotic responses
-
Ou Y, Wang SJ, Li D, Chu B, Gu W. Activation of SAT1engages polyamine metabolism with p53-mediatedferroptotic responses. Proc Natl Acad Sci USA. 2016;113:E6806-12.https://doi.org/10.1073/pnas.1607152113
-
(2016)
Proc Natl Acad Sci USA
, vol.113
, pp. E6806-E6812
-
-
Ou, Y.1
Wang, S.J.2
Li, D.3
Chu, B.4
Gu, W.5
-
25
-
-
77950486542
-
Dissecting the unique role of the retinoblastomatumor suppressor during cellular senescence
-
Chicas A, Wang X, Zhang C, McCurrach M, Zhao Z, Mert O, Dickins RA, Narita M, Zhang M, Lowe SW.Dissecting the unique role of the retinoblastomatumor suppressor during cellular senescence. CancerCell. 2010; 17:376-87. https://doi.org/10.1016/j.ccr.2010.01.023
-
(2010)
CancerCell
, vol.17
, pp. 376-387
-
-
Chicas, A.1
Wang, X.2
Zhang, C.3
McCurrach, M.4
Zhao, Z.5
Mert, O.6
Dickins, R.A.7
Narita, M.8
Zhang, M.9
Lowe, S.W.10
-
26
-
-
78650906609
-
Regulation of E2Fs and senescence byPML nuclear bodies
-
Vernier M, Bourdeau V, Gaumont-Leclerc MF, Moiseeva O, Bégin V, Saad F, Mes-Masson AM, Ferbeyre G. Regulation of E2Fs and senescence byPML nuclear bodies. Genes Dev. 2011; 25:41-50.https://doi.org/10.1101/gad.1975111
-
(2011)
Genes Dev
, vol.25
, pp. 41-50
-
-
Vernier, M.1
Bourdeau, V.2
Gaumont-Leclerc, M.F.3
Moiseeva, O.4
Bégin, V.5
Saad, F.6
Mes-Masson, A.M.7
Ferbeyre, G.8
-
27
-
-
84923899954
-
A p53/ARF-dependentanticancer barrier activates senescence and blockstumorigenesis without impacting apoptosis
-
Sinha VC, Qin L, Li Y. A p53/ARF-dependentanticancer barrier activates senescence and blockstumorigenesis without impacting apoptosis. MolCancer Res. 2015; 13:231-38. https://doi.org/10.1158/1541-7786.MCR-14-0481-T
-
(2015)
MolCancer Res
, vol.13
, pp. 231-238
-
-
Sinha, V.C.1
Qin, L.2
Li, Y.3
-
28
-
-
84953853432
-
Dynamic rolesof p53-mediated metabolic activities in ROS-inducedstress responses
-
Jiang L, Hickman JH, Wang SJ, Gu W. Dynamic rolesof p53-mediated metabolic activities in ROS-inducedstress responses. Cell Cycle. 2015; 14:2881-85.https://doi.org/10.1080/15384101.2015.1068479
-
(2015)
Cell Cycle
, vol.14
, pp. 2881-2885
-
-
Jiang, L.1
Hickman, J.H.2
Wang, S.J.3
Gu, W.4
-
29
-
-
84892685001
-
Regulation of ferroptotic cancer cell deathby GPX4
-
Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, Cheah JH, Clemons PA, Shamji AF, Clish CB, Brown LM, Girotti AW, CornishVW, et al. Regulation of ferroptotic cancer cell deathby GPX4. Cell. 2014; 156:317-31. https://doi.org/10.1016/j.cell.2013.12.010
-
(2014)
Cell
, vol.156
, pp. 317-331
-
-
Yang, W.S.1
SriRamaratnam, R.2
Welsch, M.E.3
Shimada, K.4
Skouta, R.5
Viswanathan, V.S.6
Cheah, J.H.7
Clemons, P.A.8
Shamji, A.F.9
Clish, C.B.10
Brown, L.M.11
Girotti, A.W.12
Cornish, V.W.13
-
30
-
-
33846128155
-
TheDNA damage signaling pathway is a critical mediatorof oncogene-induced senescence
-
Mallette FA, Gaumont-Leclerc MF, Ferbeyre G. TheDNA damage signaling pathway is a critical mediatorof oncogene-induced senescence. Genes Dev. 2007;21:43-48. https://doi.org/10.1101/gad.1487307
-
(2007)
Genes Dev
, vol.21
, pp. 43-48
-
-
Mallette, F.A.1
Gaumont-Leclerc, M.F.2
Ferbeyre, G.3
-
31
-
-
33845235459
-
Oncogene-induced senescence is part of thetumorigenesis barrier imposed by DNA damagecheckpoints
-
Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, Vassiliou LV, Kolettas E, NiforouK, Zoumpourlis VC, Takaoka M, Nakagawa H, Tort F, et al. Oncogene-induced senescence is part of thetumorigenesis barrier imposed by DNA damagecheckpoints. Nature. 2006; 444:633-37. https://doi.org/10.1038/nature05268
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
Rezaei, N.2
Liontos, M.3
Karakaidos, P.4
Kletsas, D.5
Issaeva, N.6
Vassiliou, L.V.7
Kolettas, E.8
Niforou, K.9
Zoumpourlis, V.C.10
Takaoka, M.11
Nakagawa, H.12
Tort, F.13
-
32
-
-
33845269825
-
Oncogene-induced senescence is a DNAdamage response triggered by DNA hyper-replication
-
Di Micco R, Fumagalli M, Cicalese A, Piccinin S, Gasparini P, Luise C, Schurra C, Garre' M, NuciforoPG, Bensimon A, Maestro R, Pelicci PG, d'Adda diFagagna F. Oncogene-induced senescence is a DNAdamage response triggered by DNA hyper-replication. Nature. 2006; 444:638-42. https://doi.org/10.1038/nature05327
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
Piccinin, S.4
Gasparini, P.5
Luise, C.6
Schurra, C.7
Garre', M.8
Nuciforo, P.G.9
Bensimon, A.10
Maestro, R.11
Pelicci, P.G.12
d'Adda diFagagna, F.13
-
33
-
-
77956851290
-
Regulation of thePML tumor suppressor in drug-induced senescenceof human normal and cancer cells by JAK/STAT-mediated signaling
-
Hubackova S, Novakova Z, Krejcikova K, Kosar M, Dobrovolna J, Duskova P, Hanzlikova H, VancurovaM, Barath P, Bartek J, Hodny Z. Regulation of thePML tumor suppressor in drug-induced senescenceof human normal and cancer cells by JAK/STAT-mediated signaling. Cell Cycle. 2010; 9:3085-99.https://doi.org/10.4161/cc.9.15.12521
-
(2010)
Cell Cycle
, vol.9
, pp. 3085-3099
-
-
Hubackova, S.1
Novakova, Z.2
Krejcikova, K.3
Kosar, M.4
Dobrovolna, J.5
Duskova, P.6
Hanzlikova, H.7
Vancurova, M.8
Barath, P.9
Bartek, J.10
Hodny, Z.11
-
34
-
-
79955623650
-
Suppressors of cytokine signaling(SOCS) proteins and JAK/STAT pathways: regulationof T-cell inflammation by SOCS1 and SOCS3
-
Tamiya T, Kashiwagi I, Takahashi R, Yasukawa H, Yoshimura A. Suppressors of cytokine signaling(SOCS) proteins and JAK/STAT pathways: regulationof T-cell inflammation by SOCS1 and SOCS3.Arterioscler Thromb Vasc Biol. 2011; 31:980-85. https://doi.org/10.1161/ATVBAHA.110.207464
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 980-985
-
-
Tamiya, T.1
Kashiwagi, I.2
Takahashi, R.3
Yasukawa, H.4
Yoshimura, A.5
-
35
-
-
84953888266
-
ATM serine-1981 phosphorylation is a plausible biomarker
-
Bakkenist CJ, Beumer JH, Schmitz JC. ATM serine-1981 phosphorylation is a plausible biomarker. CellCycle. 2015; 14:3207-08. https://doi.org/10.1080/15384101.2015.1084205
-
(2015)
CellCycle
, vol.14
, pp. 3207-3208
-
-
Bakkenist, C.J.1
Beumer, J.H.2
Schmitz, J.C.3
-
36
-
-
28244443670
-
Evidencefor the direct binding of phosphorylated p53 to sitesof DNA breaks in vivo
-
Al Rashid ST, Dellaire G, Cuddihy A, Jalali F, Vaid M, Coackley C, Folkard M, Xu Y, Chen BP, Chen DJ, LilgeL, Prise KM, Bazett Jones DP, Bristow RG. Evidencefor the direct binding of phosphorylated p53 to sitesof DNA breaks in vivo. Cancer Res. 2005; 65:10810-21.https://doi.org/10.1158/0008-5472.CAN-05-0729
-
(2005)
Cancer Res
, vol.65
, pp. 10810-10821
-
-
Al Rashid, S.T.1
Dellaire, G.2
Cuddihy, A.3
Jalali, F.4
Vaid, M.5
Coackley, C.6
Folkard, M.7
Xu, Y.8
Chen, B.P.9
Chen, D.J.10
Lilge, L.11
Prise, K.M.12
Bazett Jones, D.P.13
Bristow, R.G.14
-
37
-
-
0034114544
-
Posttranslationalmodifications of p53 in replicative senescenceoverlapping but distinct from those induced by DNAdamage
-
Webley K, Bond JA, Jones CJ, Blaydes JP, Craig A, Hupp T, Wynford-Thomas D. Posttranslationalmodifications of p53 in replicative senescenceoverlapping but distinct from those induced by DNAdamage. Mol Cell Biol. 2000; 20:2803-08. https://doi.org/10.1128/MCB.20.8.2803-2808.2000
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2803-2808
-
-
Webley, K.1
Bond, J.A.2
Jones, C.J.3
Blaydes, J.P.4
Craig, A.5
Hupp, T.6
Wynford-Thomas, D.7
-
38
-
-
79959343390
-
Two-phase dynamics ofp53 in the DNA damage response
-
Zhang XP, Liu F, Wang W. Two-phase dynamics ofp53 in the DNA damage response. Proc Natl Acad SciUSA. 2011; 108:8990-95. https://doi.org/10.1073/pnas.1100600108
-
(2011)
Proc Natl Acad SciUSA
, vol.108
, pp. 8990-8995
-
-
Zhang, X.P.1
Liu, F.2
Wang, W.3
-
39
-
-
25144496653
-
MDM2 interaction withnuclear corepressor KAP1 contributes to p53inactivation
-
Wang C, Ivanov A, Chen L, Fredericks WJ, Seto E, Rauscher FJ 3rd, Chen J. MDM2 interaction withnuclear corepressor KAP1 contributes to p53inactivation. EMBO J. 2005; 24:3279-90. https://doi.org/10.1038/sj.emboj.7600791
-
(2005)
EMBO J
, vol.24
, pp. 3279-3290
-
-
Wang, C.1
Ivanov, A.2
Chen, L.3
Fredericks, W.J.4
Seto, E.5
Rauscher III., F.J.6
Chen, J.7
-
40
-
-
33846937033
-
Senescence and tumour clearance is triggered byp53 restoration in murine liver carcinomas
-
Xue W, Zender L, Miething C, Dickins RA, HernandoE, Krizhanovsky V, Cordon-Cardo C, Lowe SW.Senescence and tumour clearance is triggered byp53 restoration in murine liver carcinomas. Nature.2007; 445:656-60. https://doi.org/10.1038/nature05529
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
Dickins, R.A.4
Hernando, E.5
Krizhanovsky, V.6
Cordon-Cardo, C.7
Lowe, S.W.8
-
41
-
-
84925426163
-
MicroRNA 155 control of p53 activity iscontext dependent and mediated by Aicda andSocs1
-
Bouamar H, Jiang D, Wang L, Lin AP, Ortega M, Aguiar RC. MicroRNA 155 control of p53 activity iscontext dependent and mediated by Aicda andSocs1. Mol Cell Biol. 2015; 35:1329-40. https://doi.org/10.1128/MCB.01446-14
-
(2015)
Mol Cell Biol
, vol.35
, pp. 1329-1340
-
-
Bouamar, H.1
Jiang, D.2
Wang, L.3
Lin, A.P.4
Ortega, M.5
Aguiar, R.C.6
-
42
-
-
84960192754
-
Sponges against miR-19 andmiR-155 reactivate the p53-Socs1 axis inhematopoietic cancers
-
Mignacca L, Saint-Germain E, Benoit A, Bourdeau V, Moro A, Ferbeyre G. Sponges against miR-19 andmiR-155 reactivate the p53-Socs1 axis inhematopoietic cancers. Cytokine. 2016; 82:80-86.https://doi.org/10.1016/j.cyto.2016.01.015
-
(2016)
Cytokine
, vol.82
, pp. 80-86
-
-
Mignacca, L.1
Saint-Germain, E.2
Benoit, A.3
Bourdeau, V.4
Moro, A.5
Ferbeyre, G.6
-
43
-
-
0026546365
-
CHOP, a novel developmentallyregulated nuclear protein that dimerizes withtranscription factors C/EBP and LAP and functions asa dominant-negative inhibitor of gene transcription
-
Ron D, Habener JF. CHOP, a novel developmentallyregulated nuclear protein that dimerizes withtranscription factors C/EBP and LAP and functions asa dominant-negative inhibitor of gene transcription. Genes Dev. 1992; 6:439-53. https://doi.org/10.1101/gad.6.3.439
-
(1992)
Genes Dev
, vol.6
, pp. 439-453
-
-
Ron, D.1
Habener, J.F.2
-
44
-
-
44649120132
-
Chemokine signaling via the CXCR2receptor reinforces senescence
-
Acosta JC, O'Loghlen A, Banito A, Guijarro MV, Augert A, Raguz S, Fumagalli M, Da Costa M, BrownC, Popov N, Takatsu Y, Melamed J, d'Adda diFagagna F, et al. Chemokine signaling via the CXCR2receptor reinforces senescence. Cell. 2008;133:1006-18.https://doi.org/10.1016/j.cell.2008.03.038
-
(2008)
Cell
, vol.133
, pp. 1006-1018
-
-
Acosta, J.C.1
O'Loghlen, A.2
Banito, A.3
Guijarro, M.V.4
Augert, A.5
Raguz, S.6
Fumagalli, M.7
Da Costa, M.8
Brown, C.9
Popov, N.10
Takatsu, Y.11
Melamed, J.12
d'Adda diFagagna, F.13
-
45
-
-
44649101304
-
Oncogene-induced senescence relayedby an interleukin-dependent inflammatory network
-
Kuilman T, Michaloglou C, Vredeveld LC, Douma S, van Doorn R, Desmet CJ, Aarden LA, Mooi WJ, Peeper DS. Oncogene-induced senescence relayedby an interleukin-dependent inflammatory network.Cell. 2008; 133:1019-31. https://doi.org/10.1016/j.cell.2008.03.039
-
(2008)
Cell
, vol.133
, pp. 1019-1031
-
-
Kuilman, T.1
Michaloglou, C.2
Vredeveld, L.C.3
Douma, S.4
van Doorn, R.5
Desmet, C.J.6
Aarden, L.A.7
Mooi, W.J.8
Peeper, D.S.9
-
46
-
-
0037011062
-
Smad-dependent GADD45beta expressionmediates delayed activation of p38 MAP kinase byTGF-beta
-
Takekawa M, Tatebayashi K, Itoh F, Adachi M, Imai K, Saito H. Smad-dependent GADD45beta expressionmediates delayed activation of p38 MAP kinase byTGF-beta. EMBO J. 2002; 21:6473-82. https://doi.org/10.1093/emboj/cdf643
-
(2002)
EMBO J
, vol.21
, pp. 6473-6482
-
-
Takekawa, M.1
Tatebayashi, K.2
Itoh, F.3
Adachi, M.4
Imai, K.5
Saito, H.6
-
47
-
-
0034598771
-
Dissociation of p53-mediated suppression of homologous recombinationfrom G1/S cell cycle checkpoint control
-
Willers H, McCarthy EE, Wu B, Wunsch H, Tang W, Taghian DG, Xia F, Powell SN. Dissociation of p53-mediated suppression of homologous recombinationfrom G1/S cell cycle checkpoint control. Oncogene.2000; 19:632-39. https://doi.org/10.1038/sj.onc.1203142
-
(2000)
Oncogene
, vol.19
, pp. 632-639
-
-
Willers, H.1
McCarthy, E.E.2
Wu, B.3
Wunsch, H.4
Tang, W.5
Taghian, D.G.6
Xia, F.7
Powell, S.N.8
-
48
-
-
0031865231
-
Specific mismatch recognition inheteroduplex intermediates by p53 suggests a role infidelity control of homologous recombination
-
Dudenhöffer C, Rohaly G, Will K, Deppert W, Wiesmüller L. Specific mismatch recognition inheteroduplex intermediates by p53 suggests a role infidelity control of homologous recombination. MolCell Biol. 1998; 18:5332-42. https://doi.org/10.1128/MCB.18.9.5332
-
(1998)
MolCell Biol
, vol.18
, pp. 5332-5342
-
-
Dudenhöffer, C.1
Rohaly, G.2
Will, K.3
Deppert, W.4
Wiesmüller, L.5
-
49
-
-
0034663873
-
PML is induced by oncogenic rasand promotes premature senescence
-
Ferbeyre G, de Stanchina E, Querido E, Baptiste N, Prives C, Lowe SW. PML is induced by oncogenic rasand promotes premature senescence. Genes Dev.2000; 14:2015-27.
-
(2000)
Genes Dev
, vol.14
, pp. 2015-2027
-
-
Ferbeyre, G.1
de Stanchina, E.2
Querido, E.3
Baptiste, N.4
Prives, C.5
Lowe, S.W.6
-
50
-
-
36849015753
-
Myc down-regulation as a mechanism to activatethe Rb pathway in STAT5A-induced senescence
-
Mallette FA, Gaumont-Leclerc MF, Huot G, FerbeyreG.Myc down-regulation as a mechanism to activatethe Rb pathway in STAT5A-induced senescence. JBiol Chem. 2007; 282:34938-44. https://doi.org/10.1074/jbc.M707074200
-
(2007)
JBiol Chem
, vol.282
, pp. 34938-34944
-
-
Mallette, F.A.1
Gaumont-Leclerc, M.F.2
Huot, G.3
Ferbeyre, G.4
-
51
-
-
85009348547
-
A transcriptome profile in hepatocellularcarcinomas based on integrated analysis ofmicroarray studies
-
Wang F, Wang R, Li Q, Qu X, Hao Y, Yang J, Zhao H, Wang Q, Li G, Zhang F, Zhang H, Zhou X, Peng X, etal. A transcriptome profile in hepatocellularcarcinomas based on integrated analysis ofmicroarray studies. Diagn Pathol. 2017; 12:4.https://doi.org/10.1186/s13000-016-0596-x
-
(2017)
Diagn Pathol
, vol.12
, pp. 4
-
-
Wang, F.1
Wang, R.2
Li, Q.3
Qu, X.4
Hao, Y.5
Yang, J.6
Zhao, H.7
Wang, Q.8
Li, G.9
Zhang, F.10
Zhang, H.11
Zhou, X.12
Peng, X.13
-
52
-
-
84875740314
-
Integrative analysis ofcomplex cancer genomics and clinical profiles using the cBioPortal
-
Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, Sun Y, Jacobsen A, Sinha R, Larsson E, Cerami E, Sander C, Schultz N. Integrative analysis ofcomplex cancer genomics and clinical profiles using the cBioPortal. Sci Signal. 2013; 6:pl1. https://doi.org/10.1126/scisignal.2004088
-
(2013)
Sci Signal
, vol.6
-
-
Gao, J.1
Aksoy, B.A.2
Dogrusoz, U.3
Dresdner, G.4
Gross, B.5
Sumer, S.O.6
Sun, Y.7
Jacobsen, A.8
Sinha, R.9
Larsson, E.10
Cerami, E.11
Sander, C.12
Schultz, N.13
-
53
-
-
79961123152
-
RSEM: accurate transcriptquantification from RNA-Seq data with or without areference genome
-
Li B, Dewey CN. RSEM: accurate transcriptquantification from RNA-Seq data with or without areference genome. BMC Bioinformatics. 2011;12:323. https://doi.org/10.1186/1471-2105-12-323
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 323
-
-
Li, B.1
Dewey, C.N.2
|