-
1
-
-
69949091124
-
An ethnopharmacological survey and in vitro confirmation of ethnopharmacological use of medicinal plants used for wound healing in Bosomtwi-Atwima-Kwanwoma area, Ghana
-
Agyare, C. et al., An ethnopharmacological survey and in vitro confirmation of ethnopharmacological use of medicinal plants used for wound healing in Bosomtwi-Atwima-Kwanwoma area, Ghana. J. Ethnopharmacol. 125 (2009), 393–403, 10.1016/j.jep.2009.07.024.
-
(2009)
J. Ethnopharmacol.
, vol.125
, pp. 393-403
-
-
Agyare, C.1
-
2
-
-
84964556093
-
Anti-inflammatory activity of aqueous leaf extract of Phyllanthus muellerianus (Kuntze) Exell. and its major constituent, geraniin
-
Boakye, Y.D., Agyare, C., Abotsi, W.K., Ayande, P.G., Ossei, P.P., Anti-inflammatory activity of aqueous leaf extract of Phyllanthus muellerianus (Kuntze) Exell. and its major constituent, geraniin. J. Ethnopharmacol. 187 (2016), 17–27, 10.1016/j.jep.2016.04.020.
-
(2016)
J. Ethnopharmacol.
, vol.187
, pp. 17-27
-
-
Boakye, Y.D.1
Agyare, C.2
Abotsi, W.K.3
Ayande, P.G.4
Ossei, P.P.5
-
3
-
-
84964000462
-
Ellagitannin geraniin: a review of the natural sources, biosynthesis, pharmacokinetics and biological effects
-
Cheng, H.S., Ton, S.H., Kadir, K.A., Ellagitannin geraniin: a review of the natural sources, biosynthesis, pharmacokinetics and biological effects. Phytochem. Rev. 16 (2017), 159–193, 10.1007/s11101-016-9464-2.
-
(2017)
Phytochem. Rev.
, vol.16
, pp. 159-193
-
-
Cheng, H.S.1
Ton, S.H.2
Kadir, K.A.3
-
4
-
-
79960738872
-
Metabolites of the ellagitannin geraniin and their antioxidant activities
-
Ito, H., Metabolites of the ellagitannin geraniin and their antioxidant activities. Planta Med. 77 (2011), 1110–1115, 10.1055/s-0030-1270749.
-
(2011)
Planta Med.
, vol.77
, pp. 1110-1115
-
-
Ito, H.1
-
5
-
-
38949106503
-
Identification of urinary and intestinal bacterial metabolites of ellagitannin geraniin in rats
-
Ito, H., Iguchi, A., Hatano, T., Identification of urinary and intestinal bacterial metabolites of ellagitannin geraniin in rats. J. Agric. Food Chem. 56 (2008), 393–400, 10.1021/jf0726942.
-
(2008)
J. Agric. Food Chem.
, vol.56
, pp. 393-400
-
-
Ito, H.1
Iguchi, A.2
Hatano, T.3
-
6
-
-
79955692116
-
Ellagitannins from Phyllanthus muellerianus (Kuntze) Exell.: geraniin and furosin stimulate cellular activity, differentiation and collagen synthesis of human skin keratinocytes and dermal fibroblasts
-
Agyare, C., Lechtenberg, M., Deters, A., Petereit, F., Hensel, A., Ellagitannins from Phyllanthus muellerianus (Kuntze) Exell.: geraniin and furosin stimulate cellular activity, differentiation and collagen synthesis of human skin keratinocytes and dermal fibroblasts. Phytomedicine 18 (2011), 617–624, 10.1016/j.phymed.2010.08.020.
-
(2011)
Phytomedicine
, vol.18
, pp. 617-624
-
-
Agyare, C.1
Lechtenberg, M.2
Deters, A.3
Petereit, F.4
Hensel, A.5
-
7
-
-
33847775740
-
The in vitro activity of geraniin and 1,3,4,6-tetra-O-galloyl-beta-D-glucose isolated from Phyllanthus urinaria against herpes simplex virus type 1 and type 2 infection
-
Yang, C.M., Cheng, H.Y., Lin, T.C., Chiang, L.C., Lin, C.C., The in vitro activity of geraniin and 1,3,4,6-tetra-O-galloyl-beta-D-glucose isolated from Phyllanthus urinaria against herpes simplex virus type 1 and type 2 infection. J. Ethnopharmacol. 110 (2007), 555–558, 10.1016/j.jep.2006.09.039.
-
(2007)
J. Ethnopharmacol.
, vol.110
, pp. 555-558
-
-
Yang, C.M.1
Cheng, H.Y.2
Lin, T.C.3
Chiang, L.C.4
Lin, C.C.5
-
8
-
-
84862822935
-
Antiviral effect of geraniin on human enterovirus 71 in vitro and in vivo
-
Yang, Y., Zhang, L., Fan, X., Qin, C., Liu, J., Antiviral effect of geraniin on human enterovirus 71 in vitro and in vivo. Bioorg. Med. Chem. Lett. 22 (2012), 2209–2211, 10.1016/j.bmcl.2012.01.102.
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 2209-2211
-
-
Yang, Y.1
Zhang, L.2
Fan, X.3
Qin, C.4
Liu, J.5
-
9
-
-
84987837934
-
Identification of hydrolyzable tannins (punicalagin, punicalin and geraniin) as novel inhibitors of hepatitis B virus covalently closed circular DNA
-
Liu, C. et al., Identification of hydrolyzable tannins (punicalagin, punicalin and geraniin) as novel inhibitors of hepatitis B virus covalently closed circular DNA. Antivir. Res. 134 (2016), 97–107, 10.1016/j.antiviral.2016.08.026.
-
(2016)
Antivir. Res.
, vol.134
, pp. 97-107
-
-
Liu, C.1
-
10
-
-
84983587918
-
Geraniin induces apoptosis of human breast cancer cells MCF-7 via ROS-mediated stimulation of p38 MAPK
-
Zhai, J.W. et al., Geraniin induces apoptosis of human breast cancer cells MCF-7 via ROS-mediated stimulation of p38 MAPK. Toxicol. Mech. Methods 26 (2016), 311–318, 10.3109/15376516.2016.1139025.
-
(2016)
Toxicol. Mech. Methods
, vol.26
, pp. 311-318
-
-
Zhai, J.W.1
-
11
-
-
85020297919
-
Geraniin suppresses ovarian cancer growth through inhibition of NF-kappaB activation and downregulation of Mcl-1 expression
-
Wang, X. et al., Geraniin suppresses ovarian cancer growth through inhibition of NF-kappaB activation and downregulation of Mcl-1 expression. J. Biochem. Mol. Toxicol., 2017, 10.1002/jbt.21929.
-
(2017)
J. Biochem. Mol. Toxicol.
-
-
Wang, X.1
-
12
-
-
85017210612
-
Protective effect of geraniin against carbon tetrachloride induced acute hepatotoxicity in Swiss albino mice
-
Aayadi, H., Mittal, S.P.K., Deshpande, A., Gore, M., Ghaskadbi, S.S., Protective effect of geraniin against carbon tetrachloride induced acute hepatotoxicity in Swiss albino mice. Biochem. Biophys. Res. Commun. 487 (2017), 62–67, 10.1016/j.bbrc.2017.04.013.
-
(2017)
Biochem. Biophys. Res. Commun.
, vol.487
, pp. 62-67
-
-
Aayadi, H.1
Mittal, S.P.K.2
Deshpande, A.3
Gore, M.4
Ghaskadbi, S.S.5
-
13
-
-
84870768499
-
Geraniin and amariin, ellagitannins from Phyllanthus amarus, protect liver cells against ethanol induced cytotoxicity
-
Londhe, J.S., Devasagayam, T.P., Foo, L.Y., Shastry, P., Ghaskadbi, S.S., Geraniin and amariin, ellagitannins from Phyllanthus amarus, protect liver cells against ethanol induced cytotoxicity. Fitoterapia 83 (2012), 1562–1568, 10.1016/j.fitote.2012.09.003.
-
(2012)
Fitoterapia
, vol.83
, pp. 1562-1568
-
-
Londhe, J.S.1
Devasagayam, T.P.2
Foo, L.Y.3
Shastry, P.4
Ghaskadbi, S.S.5
-
14
-
-
84882865770
-
In vitro BACE1 inhibitory activity of geraniin and corilagin from Geranium thunbergii
-
Youn, K., Jun, M., In vitro BACE1 inhibitory activity of geraniin and corilagin from Geranium thunbergii. Planta Med. 79 (2013), 1038–1042, 10.1055/s-0032-1328769.
-
(2013)
Planta Med.
, vol.79
, pp. 1038-1042
-
-
Youn, K.1
Jun, M.2
-
15
-
-
84930683137
-
Geraniin exerts cytoprotective effect against cellular oxidative stress by upregulation of Nrf2-mediated antioxidant enzyme expression via PI3K/AKT and ERK1/2 pathway
-
Wang, P. et al., Geraniin exerts cytoprotective effect against cellular oxidative stress by upregulation of Nrf2-mediated antioxidant enzyme expression via PI3K/AKT and ERK1/2 pathway. Biochim. Biophys. Acta 1850 (2015), 1751–1761, 10.1016/j.bbagen.2015.04.010.
-
(2015)
Biochim. Biophys. Acta
, vol.1850
, pp. 1751-1761
-
-
Wang, P.1
-
16
-
-
84876361767
-
Geraniin down regulates gamma radiation-induced apoptosis by suppressing DNA damage
-
Bing, S.J. et al., Geraniin down regulates gamma radiation-induced apoptosis by suppressing DNA damage. Food Chem. Toxicol. 57 (2013), 147–153, 10.1016/j.fct.2013.03.022.
-
(2013)
Food Chem. Toxicol.
, vol.57
, pp. 147-153
-
-
Bing, S.J.1
-
17
-
-
0035159089
-
New TNF-alpha releasing inhibitors, geraniin and corilagin, in leaves of Acer nikoense, Megusurino-ki
-
Okabe, S. et al., New TNF-alpha releasing inhibitors, geraniin and corilagin, in leaves of Acer nikoense, Megusurino-ki. Biol. Pharm. Bull. 24 (2001), 1145–1148.
-
(2001)
Biol. Pharm. Bull.
, vol.24
, pp. 1145-1148
-
-
Okabe, S.1
-
18
-
-
84992109043
-
Methylated urolithin A, the modified ellagitannin-derived metabolite, suppresses cell viability of DU145 human prostate cancer cells via targeting miR-21
-
Zhou, B., Wang, J., Zheng, G., Qiu, Z., Methylated urolithin A, the modified ellagitannin-derived metabolite, suppresses cell viability of DU145 human prostate cancer cells via targeting miR-21. Food Chem. Toxicol. 97 (2016), 375–384, 10.1016/j.fct.2016.10.005.
-
(2016)
Food Chem. Toxicol.
, vol.97
, pp. 375-384
-
-
Zhou, B.1
Wang, J.2
Zheng, G.3
Qiu, Z.4
-
19
-
-
84979519422
-
Urolithin A suppresses the proliferation of endometrial cancer cells by mediating estrogen receptor-alpha-dependent gene expression
-
Zhang, W. et al., Urolithin A suppresses the proliferation of endometrial cancer cells by mediating estrogen receptor-alpha-dependent gene expression. Mol. Nutr. Food Res. 60 (2016), 2387–2395, 10.1002/mnfr.201600048.
-
(2016)
Mol. Nutr. Food Res.
, vol.60
, pp. 2387-2395
-
-
Zhang, W.1
-
20
-
-
85021764255
-
Potential antiproliferative activity of polyphenol metabolites against human breast cancer cells and their urine excretion pattern in healthy subjects following acute intake of a polyphenol-rich juice of grumixama (Eugenia brasiliensis Lam.)
-
Teixeira, L.L. et al., Potential antiproliferative activity of polyphenol metabolites against human breast cancer cells and their urine excretion pattern in healthy subjects following acute intake of a polyphenol-rich juice of grumixama (Eugenia brasiliensis Lam.). Food Funct. 8 (2017), 2266–2274, 10.1039/c7fo00076f.
-
(2017)
Food Funct.
, vol.8
, pp. 2266-2274
-
-
Teixeira, L.L.1
-
21
-
-
84940773386
-
Urolithins, gut microbiota-derived metabolites of ellagitannins, inhibit LPS-induced inflammation in RAW 264.7 murine macrophages
-
Piwowarski, J.P., Kiss, A.K., Granica, S., Moeslinger, T., Urolithins, gut microbiota-derived metabolites of ellagitannins, inhibit LPS-induced inflammation in RAW 264.7 murine macrophages. Mol. Nutr. Food Res. 59 (2015), 2168–2177, 10.1002/mnfr.201500264.
-
(2015)
Mol. Nutr. Food Res.
, vol.59
, pp. 2168-2177
-
-
Piwowarski, J.P.1
Kiss, A.K.2
Granica, S.3
Moeslinger, T.4
-
22
-
-
84905560024
-
Role of human gut microbiota metabolism in the anti-inflammatory effect of traditionally used ellagitannin-rich plant materials
-
Piwowarski, J.P. et al., Role of human gut microbiota metabolism in the anti-inflammatory effect of traditionally used ellagitannin-rich plant materials. J. Ethnopharmacol. 155 (2014), 801–809, 10.1016/j.jep.2014.06.032.
-
(2014)
J. Ethnopharmacol.
, vol.155
, pp. 801-809
-
-
Piwowarski, J.P.1
-
23
-
-
84951908279
-
Macrophage development and polarization in chronic inflammation
-
Motwani, M.P., Gilroy, D.W., Macrophage development and polarization in chronic inflammation. Semin. Immunol. 27 (2015), 257–266, 10.1016/j.smim.2015.07.002.
-
(2015)
Semin. Immunol.
, vol.27
, pp. 257-266
-
-
Motwani, M.P.1
Gilroy, D.W.2
-
24
-
-
84988649474
-
Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production
-
Baseler, W.A. et al., Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production. Redox Biol. 10 (2016), 12–23, 10.1016/j.redox.2016.09.005.
-
(2016)
Redox Biol.
, vol.10
, pp. 12-23
-
-
Baseler, W.A.1
-
25
-
-
77952865796
-
Phagocyte partnership during the onset and resolution of inflammation
-
Soehnlein, O., Lindbom, L., Phagocyte partnership during the onset and resolution of inflammation. Nat. Rev. Immunol. 10 (2010), 427–439, 10.1038/nri2779.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 427-439
-
-
Soehnlein, O.1
Lindbom, L.2
-
26
-
-
84924368520
-
Tissue-resident macrophages: then and now
-
Davies, L.C., Taylor, P.R., Tissue-resident macrophages: then and now. Immunology 144 (2015), 541–548, 10.1111/imm.12451.
-
(2015)
Immunology
, vol.144
, pp. 541-548
-
-
Davies, L.C.1
Taylor, P.R.2
-
27
-
-
84906055605
-
Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes
-
Esser, N., Legrand-Poels, S., Piette, J., Scheen, A.J., Paquot, N., Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes. Diabetes Res. Clin. Pract. 105 (2014), 141–150, 10.1016/j.diabres.2014.04.006.
-
(2014)
Diabetes Res. Clin. Pract.
, vol.105
, pp. 141-150
-
-
Esser, N.1
Legrand-Poels, S.2
Piette, J.3
Scheen, A.J.4
Paquot, N.5
-
28
-
-
85010208256
-
Alzheimer's disease: innate immunity gone awry?
-
VanItallie, T.B., Alzheimer's disease: innate immunity gone awry?. Metabolism 69S (2017), S41–S49, 10.1016/j.metabol.2017.01.014.
-
(2017)
Metabolism
, vol.69S
, pp. S41-S49
-
-
VanItallie, T.B.1
-
29
-
-
85014637972
-
Pomegranate polyphenolics reduce inflammation and ulceration in intestinal colitis-involvement of the miR-145/p70S6K1/HIF1alpha axis in vivo and in vitro
-
Kim, H. et al., Pomegranate polyphenolics reduce inflammation and ulceration in intestinal colitis-involvement of the miR-145/p70S6K1/HIF1alpha axis in vivo and in vitro. J. Nutr. Biochem. 43 (2017), 107–115, 10.1016/j.jnutbio.2017.02.005.
-
(2017)
J. Nutr. Biochem.
, vol.43
, pp. 107-115
-
-
Kim, H.1
-
30
-
-
85028254772
-
Comparison of anti-inflammatory mechanisms of mango (Mangifera indica L.) and pomegranate (Punica granatum L.) in a preclinical model of colitis
-
Kim, H. et al., Comparison of anti-inflammatory mechanisms of mango (Mangifera indica L.) and pomegranate (Punica granatum L.) in a preclinical model of colitis. Mol. Nutr. Food Res. 60 (2016), 1912–1923, 10.1002/mnfr.201501008.
-
(2016)
Mol. Nutr. Food Res.
, vol.60
, pp. 1912-1923
-
-
Kim, H.1
-
31
-
-
84875052383
-
Modulation of Nrf2-dependent gene transcription by bilberry anthocyanins in vivo
-
Kropat, C. et al., Modulation of Nrf2-dependent gene transcription by bilberry anthocyanins in vivo. Mol. Nutr. Food Res. 57 (2013), 545–550, 10.1002/mnfr.201200504.
-
(2013)
Mol. Nutr. Food Res.
, vol.57
, pp. 545-550
-
-
Kropat, C.1
-
32
-
-
84969857864
-
Activated AMPK boosts the Nrf2/HO-1 signaling axis—a role for the unfolded protein response
-
Zimmermann, K. et al., Activated AMPK boosts the Nrf2/HO-1 signaling axis—a role for the unfolded protein response. Free Radic. Biol. Med. 88 (2015), 417–426, 10.1016/j.freeradbiomed.2015.03.030.
-
(2015)
Free Radic. Biol. Med.
, vol.88
, pp. 417-426
-
-
Zimmermann, K.1
-
33
-
-
84884684046
-
Honokiol: a non-adipogenic PPARgamma agonist from nature
-
Atanasov, A.G. et al., Honokiol: a non-adipogenic PPARgamma agonist from nature. Biochim. Biophys. Acta 1830 (2013), 4813–4819, 10.1016/j.bbagen.2013.06.021.
-
(2013)
Biochim. Biophys. Acta
, vol.1830
, pp. 4813-4819
-
-
Atanasov, A.G.1
-
34
-
-
84894663300
-
Discovery of new liver X receptor agonists by pharmacophore modeling and shape-based virtual screening
-
Temml, V., Voss, C.V., Dirsch, V.M., Schuster, D., Discovery of new liver X receptor agonists by pharmacophore modeling and shape-based virtual screening. J. Chem. Inf. Model. 54 (2014), 367–371, 10.1021/ci400682b.
-
(2014)
J. Chem. Inf. Model.
, vol.54
, pp. 367-371
-
-
Temml, V.1
Voss, C.V.2
Dirsch, V.M.3
Schuster, D.4
-
35
-
-
84969528739
-
Inhibitory effects of geraniin on LPS-induced inflammation via regulating NF-kappaB and Nrf2 pathways in RAW 264.7 cells
-
Wang, P. et al., Inhibitory effects of geraniin on LPS-induced inflammation via regulating NF-kappaB and Nrf2 pathways in RAW 264.7 cells. Chem. Biol. Interact. 253 (2016), 134–142, 10.1016/j.cbi.2016.05.014.
-
(2016)
Chem. Biol. Interact.
, vol.253
, pp. 134-142
-
-
Wang, P.1
-
36
-
-
85029743545
-
Urolithin A mitigates cisplatin-induced nephrotoxicity by inhibiting renal inflammation and apoptosis in an experimental rat model
-
Guada, M., Ganugula, R., Vadhanam, M., Majeti, R.K., Urolithin A mitigates cisplatin-induced nephrotoxicity by inhibiting renal inflammation and apoptosis in an experimental rat model. J. Pharmacol. Exp. Ther., 2017, 10.1124/jpet.117.242420.
-
(2017)
J. Pharmacol. Exp. Ther.
-
-
Guada, M.1
Ganugula, R.2
Vadhanam, M.3
Majeti, R.K.4
-
37
-
-
0034965596
-
Peroxisome proliferator-activated receptors in inflammation control
-
Delerive, P., Fruchart, J.C., Staels, B., Peroxisome proliferator-activated receptors in inflammation control. J. Endocrinol. 169 (2001), 453–459.
-
(2001)
J. Endocrinol.
, vol.169
, pp. 453-459
-
-
Delerive, P.1
Fruchart, J.C.2
Staels, B.3
-
38
-
-
0033793133
-
Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation
-
Chinetti, G., Fruchart, J.C., Staels, B., Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflamm. Res. 49 (2000), 497–505, 10.1007/s000110050622.
-
(2000)
Inflamm. Res.
, vol.49
, pp. 497-505
-
-
Chinetti, G.1
Fruchart, J.C.2
Staels, B.3
-
39
-
-
85020376836
-
Liver X receptors link lipid metabolism and inflammation
-
Schulman, I.G., Liver X receptors link lipid metabolism and inflammation. FEBS Lett., 2017, 10.1002/1873-3468.12702.
-
(2017)
FEBS Lett.
-
-
Schulman, I.G.1
-
40
-
-
33644652410
-
Role of the Nrf2-mediated signaling pathway as a negative regulator of inflammation: implications for the impact of particulate pollutants on asthma
-
Li, N., Nel, A.E., Role of the Nrf2-mediated signaling pathway as a negative regulator of inflammation: implications for the impact of particulate pollutants on asthma. Antioxid. Redox Signal. 8 (2006), 88–98, 10.1089/ars.2006.8.88.
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 88-98
-
-
Li, N.1
Nel, A.E.2
-
41
-
-
78049370987
-
Oxidative stress, inflammation, and cancer: how are they linked?
-
Reuter, S., Gupta, S.C., Chaturvedi, M.M., Aggarwal, B.B., Oxidative stress, inflammation, and cancer: how are they linked?. Free Radic. Biol. Med. 49 (2010), 1603–1616, 10.1016/j.freeradbiomed.2010.09.006.
-
(2010)
Free Radic. Biol. Med.
, vol.49
, pp. 1603-1616
-
-
Reuter, S.1
Gupta, S.C.2
Chaturvedi, M.M.3
Aggarwal, B.B.4
-
42
-
-
84978136448
-
Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
-
Ryu, D. et al., Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents. Nat. Med. 22 (2016), 879–888, 10.1038/nm.4132.
-
(2016)
Nat. Med.
, vol.22
, pp. 879-888
-
-
Ryu, D.1
-
43
-
-
33646840681
-
Autophagy: a protective mechanism in response to stress and inflammation
-
Heymann, D., Autophagy: a protective mechanism in response to stress and inflammation. Curr. Opin. Investig. Drugs 7 (2006), 443–450.
-
(2006)
Curr. Opin. Investig. Drugs
, vol.7
, pp. 443-450
-
-
Heymann, D.1
-
44
-
-
34548700796
-
Unveiling the roles of autophagy in innate and adaptive immunity
-
Levine, B., Deretic, V., Unveiling the roles of autophagy in innate and adaptive immunity. Nat. Rev. Immunol. 7 (2007), 767–777, 10.1038/nri2161.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 767-777
-
-
Levine, B.1
Deretic, V.2
-
45
-
-
70349924078
-
Links between autophagy, innate immunity, inflammation and Crohn's disease
-
Deretic, V., Links between autophagy, innate immunity, inflammation and Crohn's disease. Dig. Dis. 27 (2009), 246–251, 10.1159/000228557.
-
(2009)
Dig. Dis.
, vol.27
, pp. 246-251
-
-
Deretic, V.1
-
46
-
-
85013763791
-
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
-
Klionsky, D.J. et al., Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12 (2016), 1–222, 10.1080/15548627.2015.1100356.
-
(2016)
Autophagy
, vol.12
, pp. 1-222
-
-
Klionsky, D.J.1
-
47
-
-
53549113031
-
The role of TOR in autophagy regulation from yeast to plants and mammals
-
Diaz-Troya, S., Perez-Perez, M.E., Florencio, F.J., Crespo, J.L., The role of TOR in autophagy regulation from yeast to plants and mammals. Autophagy 4 (2008), 851–865.
-
(2008)
Autophagy
, vol.4
, pp. 851-865
-
-
Diaz-Troya, S.1
Perez-Perez, M.E.2
Florencio, F.J.3
Crespo, J.L.4
-
48
-
-
77950501014
-
mTOR regulation of autophagy
-
Jung, C.H., Ro, S.H., Cao, J., Otto, N.M., Kim, D.H., mTOR regulation of autophagy. FEBS Lett. 584 (2010), 1287–1295, 10.1016/j.febslet.2010.01.017.
-
(2010)
FEBS Lett.
, vol.584
, pp. 1287-1295
-
-
Jung, C.H.1
Ro, S.H.2
Cao, J.3
Otto, N.M.4
Kim, D.H.5
-
49
-
-
85018383859
-
The lysosome: a crucial hub for AMPK and mTORC1 signalling
-
Carroll, B., Dunlop, E.A., The lysosome: a crucial hub for AMPK and mTORC1 signalling. Biochem. J. 474 (2017), 1453–1466, 10.1042/BCJ20160780.
-
(2017)
Biochem. J.
, vol.474
, pp. 1453-1466
-
-
Carroll, B.1
Dunlop, E.A.2
-
50
-
-
84971554164
-
5′-Monophosphate-activated protein kinase (AMPK) improves autophagic activity in diabetes and diabetic complications
-
Yao, F., Zhang, M., Chen, L., 5′-Monophosphate-activated protein kinase (AMPK) improves autophagic activity in diabetes and diabetic complications. Acta Pharm. Sin. B 6 (2016), 20–25, 10.1016/j.apsb.2015.07.009.
-
(2016)
Acta Pharm. Sin. B
, vol.6
, pp. 20-25
-
-
Yao, F.1
Zhang, M.2
Chen, L.3
-
51
-
-
84859778293
-
mTOR signaling in growth control and disease
-
Laplante, M., Sabatini, D.M., mTOR signaling in growth control and disease. Cell 149 (2012), 274–293, 10.1016/j.cell.2012.03.017.
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
52
-
-
0038676409
-
Inhibition of histone deacetylase activity by butyrate
-
Davie, J.R., Inhibition of histone deacetylase activity by butyrate. J. Nutr. 133 (2003), 2485S–2493S.
-
(2003)
J. Nutr.
, vol.133
, pp. 2485S-2493S
-
-
Davie, J.R.1
-
53
-
-
84995414949
-
Diet, microorganisms and their metabolites, and colon cancer
-
O'Keefe, S.J., Diet, microorganisms and their metabolites, and colon cancer. Nat. Rev. Gastroenterol. Hepatol. 13 (2016), 691–706, 10.1038/nrgastro.2016.165.
-
(2016)
Nat. Rev. Gastroenterol. Hepatol.
, vol.13
, pp. 691-706
-
-
O'Keefe, S.J.1
-
54
-
-
84881089726
-
Ellagitannins from Rubus berries for the control of gastric inflammation: in vitro and in vivo studies
-
Sangiovanni, E. et al., Ellagitannins from Rubus berries for the control of gastric inflammation: in vitro and in vivo studies. PLoS One, 8, 2013, e71762, 10.1371/journal.pone.0071762.
-
(2013)
PLoS One
, vol.8
-
-
Sangiovanni, E.1
-
55
-
-
84862168115
-
Anti-inflammatory effects of polyphenolic-enriched red raspberry extract in an antigen-induced arthritis rat model
-
Jean-Gilles, D. et al., Anti-inflammatory effects of polyphenolic-enriched red raspberry extract in an antigen-induced arthritis rat model. J. Agric. Food Chem. 60 (2012), 5755–5762, 10.1021/jf203456w.
-
(2012)
J. Agric. Food Chem.
, vol.60
, pp. 5755-5762
-
-
Jean-Gilles, D.1
-
56
-
-
84977563497
-
Urolithins, the rescue of “old”metabolites to understand a “new” concept: metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health status
-
Tomas-Barberan, F.A. et al., Urolithins, the rescue of “old”metabolites to understand a “new” concept: metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health status. Mol. Nutr. Food Res., 61, 2017, xx, 10.1002/mnfr.201500901.
-
(2017)
Mol. Nutr. Food Res.
, vol.61
, pp. xx
-
-
Tomas-Barberan, F.A.1
-
57
-
-
84879387618
-
Biological significance of urolithins, the gut microbial ellagic-acid-derived metabolites: the evidence so far
-
Espin, J.C., Larrose, M., Garcia-Conesa, M.T., Tomas-Barberan, F., Biological significance of urolithins, the gut microbial ellagic-acid-derived metabolites: the evidence so far. Evid. Based Complement. Alternat. Med., 2013, 2013, 270418, 10.1155/2013/270418.
-
(2013)
Evid. Based Complement. Alternat. Med.
, vol.2013
, pp. 270418
-
-
Espin, J.C.1
Larrose, M.2
Garcia-Conesa, M.T.3
Tomas-Barberan, F.4
-
58
-
-
85021751510
-
In vivo administration of urolithin A and B prevents the occurrence of cardiac dysfunction in streptozotocin-induced diabetic rats
-
Savi, M. et al., In vivo administration of urolithin A and B prevents the occurrence of cardiac dysfunction in streptozotocin-induced diabetic rats. Cardiovasc. Diabetol., 16, 2017, 80, 10.1186/s12933-017-0561-3.
-
(2017)
Cardiovasc. Diabetol.
, vol.16
, pp. 80
-
-
Savi, M.1
-
59
-
-
85019259090
-
Phase II conjugates of urolithins isolated from human urine and potential role of β-glucuronidases in their disposition
-
Piwowarski, J.P., Stanisławska, I., Granica, S., Stefańska, J., Kiss, A.K., Phase II conjugates of urolithins isolated from human urine and potential role of β-glucuronidases in their disposition. Drug Metab. Dispos. 45 (2017), 657–665, 10.1124/dmd.117.075200.
-
(2017)
Drug Metab. Dispos.
, vol.45
, pp. 657-665
-
-
Piwowarski, J.P.1
Stanisławska, I.2
Granica, S.3
Stefańska, J.4
Kiss, A.K.5
-
60
-
-
85021980911
-
Punicalagin, a PTP1B inhibitor, induces M2c phenotype polarization via up-regulation of HO-1 in murine macrophages
-
Xu, X. et al., Punicalagin, a PTP1B inhibitor, induces M2c phenotype polarization via up-regulation of HO-1 in murine macrophages. Free Radic. Biol. Med. 110 (2017), 408–420, 10.1016/j.freeradbiomed.2017.06.014.
-
(2017)
Free Radic. Biol. Med.
, vol.110
, pp. 408-420
-
-
Xu, X.1
-
61
-
-
75649108606
-
Role of autophagy and autophagy genes in inflammatory bowel disease
-
Cadwell, K., Stappenbeck, T.S., Virgin, H.W., Role of autophagy and autophagy genes in inflammatory bowel disease. Curr. Top. Microbiol. Immunol. 335 (2009), 141–167, 10.1007/978-3-642-00302-8_7.
-
(2009)
Curr. Top. Microbiol. Immunol.
, vol.335
, pp. 141-167
-
-
Cadwell, K.1
Stappenbeck, T.S.2
Virgin, H.W.3
-
62
-
-
79956131536
-
Autophagy shapes inflammation
-
Fesus, L., Demeny, M.A., Petrovski, G., Autophagy shapes inflammation. Antioxid. Redox Signal. 14 (2011), 2233–2243, 10.1089/ars.2010.3485.
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 2233-2243
-
-
Fesus, L.1
Demeny, M.A.2
Petrovski, G.3
-
63
-
-
78751672975
-
Autophagy in immunity and inflammation
-
Levine, B., Mizushima, N., Virgin, H.W., Autophagy in immunity and inflammation. Nature 469 (2011), 323–335, 10.1038/nature09782.
-
(2011)
Nature
, vol.469
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
64
-
-
85027940025
-
Urolithin A attenuates ox-LDL-induced endothelial dysfunction partly by modulating microRNA-27 and ERK/PPAR-gamma pathway
-
Han, Q.A. et al., Urolithin A attenuates ox-LDL-induced endothelial dysfunction partly by modulating microRNA-27 and ERK/PPAR-gamma pathway. Mol. Nutr. Food Res. 60 (2016), 1933–1943, 10.1002/mnfr.201500827.
-
(2016)
Mol. Nutr. Food Res.
, vol.60
, pp. 1933-1943
-
-
Han, Q.A.1
-
65
-
-
85016969413
-
Geraniin attenuates LPS-induced acute lung injury via inhibiting NF-kappaB and activating Nrf2 signaling pathways
-
Zhu, G. et al., Geraniin attenuates LPS-induced acute lung injury via inhibiting NF-kappaB and activating Nrf2 signaling pathways. Oncotarget 8 (2017), 22835–22841, 10.18632/oncotarget.15227.
-
(2017)
Oncotarget
, vol.8
, pp. 22835-22841
-
-
Zhu, G.1
-
66
-
-
85018784717
-
Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages
-
Ip, W.K.E., Hoshi, N., Shouval, D.S., Snapper, S., Medzhitov, R., Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages. Science 356 (2017), 513–519, 10.1126/science.aal3535.
-
(2017)
Science
, vol.356
, pp. 513-519
-
-
Ip, W.K.E.1
Hoshi, N.2
Shouval, D.S.3
Snapper, S.4
Medzhitov, R.5
-
67
-
-
85020871195
-
Rapamycin regulates macrophage activation by inhibiting NLRP3 inflammasome-p38 MAPK-NFkappaB pathways in autophagy- and p62-dependent manners
-
Ko, J.H., Yoon, S.O., Lee, H.J., Oh, J.Y., Rapamycin regulates macrophage activation by inhibiting NLRP3 inflammasome-p38 MAPK-NFkappaB pathways in autophagy- and p62-dependent manners. Oncotarget 8 (2017), 40817–40831, 10.18632/oncotarget.17256.
-
(2017)
Oncotarget
, vol.8
, pp. 40817-40831
-
-
Ko, J.H.1
Yoon, S.O.2
Lee, H.J.3
Oh, J.Y.4
-
68
-
-
85000428204
-
mTORC1 inhibition with rapamycin exacerbates adipose tissue inflammation in obese mice and dissociates macrophage phenotype from function
-
Paschoal, V.A. et al., mTORC1 inhibition with rapamycin exacerbates adipose tissue inflammation in obese mice and dissociates macrophage phenotype from function. Immunobiology 222 (2017), 261–271, 10.1016/j.imbio.2016.09.014.
-
(2017)
Immunobiology
, vol.222
, pp. 261-271
-
-
Paschoal, V.A.1
-
69
-
-
85029409862
-
Adipocyte mTORC1 deficiency promotes adipose tissue inflammation and NLRP3 inflammasome activation via oxidative stress and de novo ceramide synthesis
-
Chimin, P. et al., Adipocyte mTORC1 deficiency promotes adipose tissue inflammation and NLRP3 inflammasome activation via oxidative stress and de novo ceramide synthesis. J. Lipid Res., 2017, 10.1194/jlr.M074518.
-
(2017)
J. Lipid Res.
-
-
Chimin, P.1
-
70
-
-
85016742201
-
Urolithin A alleviates myocardial ischemia/reperfusion injury via PI3K/Akt pathway
-
Tang, L. et al., Urolithin A alleviates myocardial ischemia/reperfusion injury via PI3K/Akt pathway. Biochem. Biophys. Res. Commun. 486 (2017), 774–780, 10.1016/j.bbrc.2017.03.119.
-
(2017)
Biochem. Biophys. Res. Commun.
, vol.486
, pp. 774-780
-
-
Tang, L.1
-
71
-
-
85025094662
-
Chemical composition of blackberry press cake, polyphenolic extract, and defatted seeds, and their effects on cecal fermentation, bacterial metabolites, and blood lipid profile in rats
-
Kosmala, M. et al., Chemical composition of blackberry press cake, polyphenolic extract, and defatted seeds, and their effects on cecal fermentation, bacterial metabolites, and blood lipid profile in rats. J. Agric. Food Chem. 65 (2017), 5470–5479, 10.1021/acs.jafc.7b01876.
-
(2017)
J. Agric. Food Chem.
, vol.65
, pp. 5470-5479
-
-
Kosmala, M.1
-
72
-
-
85020907718
-
Autophagy in cancer therapy
-
Fulda, S., Autophagy in cancer therapy. Front. Oncol., 7, 2017, 128, 10.3389/fonc.2017.00128.
-
(2017)
Front. Oncol.
, vol.7
, pp. 128
-
-
Fulda, S.1
-
73
-
-
85019766584
-
Autophagy and mitophagy in cardiovascular disease
-
Bravo-San Pedro, J.M., Kroemer, G., Galluzzi, L., Autophagy and mitophagy in cardiovascular disease. Circ. Res. 120 (2017), 1812–1824, 10.1161/CIRCRESAHA.117.311082.
-
(2017)
Circ. Res.
, vol.120
, pp. 1812-1824
-
-
Bravo-San Pedro, J.M.1
Kroemer, G.2
Galluzzi, L.3
-
74
-
-
85008330539
-
Autophagy in the liver: functions in health and disease
-
Ueno, T., Komatsu, M., Autophagy in the liver: functions in health and disease. Nat. Rev. Gastroenterol. Hepatol. 14 (2017), 170–184, 10.1038/nrgastro.2016.185.
-
(2017)
Nat. Rev. Gastroenterol. Hepatol.
, vol.14
, pp. 170-184
-
-
Ueno, T.1
Komatsu, M.2
-
75
-
-
85027556680
-
Safety assessment of Urolithin A, a metabolite produced by the human gut microbiota upon dietary intake of plant derived ellagitannins and ellagic acid
-
Heilman, J., Andreux, P., Tran, N., Rinsch, C., Blanco-Bose, W., Safety assessment of Urolithin A, a metabolite produced by the human gut microbiota upon dietary intake of plant derived ellagitannins and ellagic acid. Food Chem. Toxicol., 2017, 10.1016/j.fct.2017.07.050.
-
(2017)
Food Chem. Toxicol.
-
-
Heilman, J.1
Andreux, P.2
Tran, N.3
Rinsch, C.4
Blanco-Bose, W.5
-
76
-
-
85025806668
-
Regulation of inflammation by microbiota interactions with the host
-
Blander, J.M., Longman, R.S., Iliev, I.D., Sonnenberg, G.F., Artis, D., Regulation of inflammation by microbiota interactions with the host. Nat. Immunol. 18 (2017), 851–860, 10.1038/ni.3780.
-
(2017)
Nat. Immunol.
, vol.18
, pp. 851-860
-
-
Blander, J.M.1
Longman, R.S.2
Iliev, I.D.3
Sonnenberg, G.F.4
Artis, D.5
|