In vivo administration of urolithin A and B prevents the occurrence of cardiac dysfunction in streptozotocin-induced diabetic rats

Cardiovascular Diabetology

Volumn 16, Issue 1, 2017, Pages

  Savi, Monia ^a   Bocchi, Leonardo ^a   Mena, Pedro ^a   Dall'Asta, Margherita ^a   Crozier, Alan ^b   Brighenti, Furio ^a   Stilli, Donatella ^a   Del Rio, Daniele ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cardiac performance; Cardiomyocyte mechanics; Diabetes; Ellagitannins; Urolithins

Indexed keywords

CARDIAC AGENT; CYTOKINE; ELLAGITANNIN; FRACTALKINE; PHOSPHOLAMBAN; PROTEIN; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; STREPTOZOCIN; UNCLASSIFIED DRUG; UROLITHIN A; UROLITHIN B; 3,8-DIHYDROXY-6H-DIBENZO(B,D)PYRAN-6-ONE; COUMARIN DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIAC MUSCLE CELL; CARDITIS; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG TISSUE LEVEL; DRUG URINE LEVEL; HEART HEMODYNAMICS; HEART MUSCLE CONTRACTILITY; HEART PERFORMANCE; HYPERGLYCEMIA; IMMUNOBLOTTING; IN VIVO STUDY; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; INTESTINE FLORA; MALE; METABOLITE; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ANIMAL; CARDIAC MUSCLE; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; HEART CONTRACTION; HEART DISEASE; METABOLISM; WISTAR RAT;

ANIMALS; COUMARINS; DIABETES MELLITUS, EXPERIMENTAL; HEART DISEASES; HYPERGLYCEMIA; MALE; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; RATS, WISTAR; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; STREPTOZOCIN;

EID: 85021751510     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/s12933-017-0561-3     Document Type: Article

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