The in vitro activity of geraniin and 1,3,4,6-tetra-O-galloyl-β-d-glucose isolated from Phyllanthus urinaria against herpes simplex virus type 1 and type 2 infection

Journal of Ethnopharmacology

Volumn 110, Issue 3, 2007, Pages 555-558

  Yang, Chien Min ^a   Cheng, Hua Yew ^b   Lin, Ta Chen ^c   Chiang, Lien Chai ^d   Lin, Chun Ching ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b TUNG FANG INSTITUTE OF TECHNOLOGY   (Taiwan)

^c CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

1,3,4,6 tetra O galloyl d glucose; Anti HSV activity; Geraniin; Phyllanthus urinaria

Indexed keywords

1,3,4,6 TETRA O GALLOYL BETA DEXTRO GLUCOSE; ACETONE; GEMIN D; GERANIIN; GLUCOSE DERIVATIVE; PHYLLANTHUS URINARIA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; EUPHORBIA; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HOST CELL; HUMAN; IC 50; IN VITRO STUDY; MEDICINAL PLANT; NONHUMAN; PHYLLANTUS URINARIA; TRADITIONAL MEDICINE; VERO CELL; VIRUS INHIBITION;

ANIMALS; ANTIVIRAL AGENTS; CERCOPITHECUS AETHIOPS; DOSE-RESPONSE RELATIONSHIP, DRUG; GALLIC ACID; GLUCOSIDES; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; HYDROLYZABLE TANNINS; KIDNEY; MEDICINE, ORIENTAL TRADITIONAL; MONOSACCHARIDES; PHYLLANTHUS; PHYTOTHERAPY; PLANT EXTRACTS; PLANTS, MEDICINAL; VERO CELLS;

EUPHORBIACEAE; HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 2; PHYLLANTHUS URINARIA; SIMPLEXVIRUS; TETRA;

EID: 33847775740     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2006.09.039     Document Type: Article

References (16)

1. Burleson F.G., Chambers T.M., and Wiedbrauk D.L. Plaque assay. In: Burleson F.G., Chambers T.M., and Wiedbrauk D.L. (Eds). Virology: A Laboratory Manual (1992), Academic Press Inc., California 74-84
2. Chang C.C., Lien Y.C., Liu K.C., and Lee S.S. Lignans from Phyllanthus urinaria. Phytochemistry 63 (2003) 825-833
3. Chinese Herbal Commission of the National Administrative Department on Chinese Medicine and Pharmacy. Chinese Herbal (1999), Shanghai Science & Technology Press, Shanghai pp. 842-843
4. Cheng H.Y., Lin T.C., Yang C.M., Wang K.C., and Lin C.C. Mechanism of action of the suppressing of herpes simplex virus type 2 replication by pterocarnin A. Microbes and Infection 6 (2004) 738-744
5. Cheng H.Y., Lin T.C., Yang C.M., Shieh D.E., and Lin C.C. In vitro anti-HSV-2 activity and mechanism action of proanthocyanidins A-1 from Vaccinium vitis-idaea. Journal of the Science of Food and Agriculture 85 (2005) 10-15
6. Chiu N.Y., and Chang K.H. The Illustrated Medicinal Plants of Taiwan vol. 3 (1998), Southern Materials Center Publishing Inc., Taipei p. 57
7. Kao M.T. Popular Herbal Remedies of Taiwan vol. 1 (1985), Southern Materials Center Publishing Inc., Taipei p. 89
8. Okuda T., Mori K., and Hatano T. The distribution of geraniin and mallotusinic acid in the order geraniales. Phytochemistry 19 (1980) 547
9. Satyan K.S., Prakash A., Singh R.P., and Srivastava R.S. Phthalic acid bis-ester and other phytoconstituents of Phyllthanus urinaria. Planta Medica 61 (1995) 293
10. Wang C.Y., and Lee S.S. Analysis and identification of lignans in Phyllanthus urinaria by HPLC-SPE-NMR. Phytochemical Analysis 16 (2005) 120-126
11. Yang C.M., Cheng H.Y., Lin T.C., Chiang L.C., and Lin C.C. Acetone, ethanol and methanol extracts of Phyllanthus urinaria inhibit HSV-2 infection in vitro. Antiviral Research 67 (2005) 24-30
12. Yang C.M., Cheng H.Y., Lin T.C., Chiang L.C., and Lin C.C. Euphorbia thymifolia suppresses herpes simplex virus-2 infection by directly inactivating virus infectivity. Clinical and Experimental Pharmacology and Physiology 32 (2005) 346-349
13. Yao Q.Q., and Zuo C.X. Chemical studies on the constituents of Phyllanthus urinaria L. Yaoxue Xuebao 28 (1993) 829-835
14. Zhang L.Z., Guo Y.J., Tu G.Z., Guo W.B., and Miao F. Studies on chemical constituents of Phyllanthus urinaria L. Zhongguo Zhong Yao Za Zhi 25 (2000) 615-617
15. Zhang L.Z., Guo Y.J., Tu G.Z., Miao F., and Guo W.B. Isolation and identification of a noval polyphenolic compound from Phyllanthus urinaria L. Zhongguo Zhong Yao Za Zhi 25 (2000) 724-725
16. Zhang L.Z., Guo Y.J., Tu G.Z., Guo W.B., and Miao F. Isolation and identification of a novel ellagitannin from Phyllanthus urinaria L. Yao Xue Xue Bao 39 (2004) 119-122