Methylated urolithin A, the modified ellagitannin-derived metabolite, suppresses cell viability of DU145 human prostate cancer cells via targeting miR-21

Food and Chemical Toxicology

Volumn 97, Issue , 2016, Pages 375-384

  Zhou, Benhong ^a   Wang, Jing ^a   Zheng, Guohua ^b   Qiu, Zhenpeng ^b  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b HUBEI UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Akt; Methylated urolithin A; miR 21; PTEN; catenin

Indexed keywords

BETA CATENIN; CASPASE; ELLAGITANNIN; MATRILYSIN; MEMBRANE PROTEIN; METHYLATED UROLITHIN A; MICRORNA 21; MYC PROTEIN; PDCD4 PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG; WNT PROTEIN; 3,8-DIHYDROXY-6H-DIBENZO(B,D)PYRAN-6-ONE; APOPTOSIS REGULATORY PROTEIN; COUMARIN DERIVATIVE; FOXO3 PROTEIN, HUMAN; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HNF1A PROTEIN, HUMAN; LYMPHOID ENHANCER FACTOR 1; MESSENGER RNA; MICRORNA; MIRN21 MICRORNA, HUMAN; PDCD4 PROTEIN, HUMAN; PTEN PROTEIN, HUMAN; RNA BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CELL VIABILITY; CONTROLLED STUDY; DEPOLARIZATION; DOWN REGULATION; DRUG TARGETING; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NONHUMAN; PROSTATE CANCER; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; ANIMAL; BAGG ALBINO MOUSE; CELL PROLIFERATION; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; METHYLATION; NUDE MOUSE; PATHOLOGY; PROSTATIC NEOPLASMS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE; WESTERN BLOTTING; WNT SIGNALING PATHWAY;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BETA CATENIN; BLOTTING, WESTERN; CELL PROLIFERATION; COUMARINS; FORKHEAD BOX PROTEIN O3; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HUMANS; LYMPHOID ENHANCER-BINDING FACTOR 1; MALE; METHYLATION; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA-BINDING PROTEINS; TUMOR CELLS, CULTURED; WNT SIGNALING PATHWAY; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84992109043     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2016.10.005     Document Type: Article

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