메뉴 건너뛰기




Volumn 26, Issue 6, 2017, Pages 842-855.e5

Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence

Author keywords

acetyl CoA; acetylation; breast cancer; EMT; leptin; metastasis; pACC

Indexed keywords

ACETYL COENZYME A; ACETYL COENZYME A CARBOXYLASE; ACETYL COENZYME A CARBOXYLASE 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LEPTIN; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG; ACACA PROTEIN, HUMAN; ACC1 PROTEIN, MOUSE;

EID: 85031776911     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2017.09.018     Document Type: Article
Times cited : (202)

References (47)
  • 3
    • 23044482013 scopus 로고    scopus 로고
    • RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells
    • Brusselmans, K., De Schrijver, E., Verhoeven, G., Swinnen, J.V., RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells. Cancer Res. 65 (2005), 6719–6725.
    • (2005) Cancer Res. , vol.65 , pp. 6719-6725
    • Brusselmans, K.1    De Schrijver, E.2    Verhoeven, G.3    Swinnen, J.V.4
  • 4
    • 79953147370 scopus 로고    scopus 로고
    • A perspective on cancer cell metastasis
    • Chaffer, C.L., Weinberg, R.A., A perspective on cancer cell metastasis. Science 331 (2011), 1559–1564.
    • (2011) Science , vol.331 , pp. 1559-1564
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 5
    • 33744808464 scopus 로고    scopus 로고
    • Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival
    • Chajès, V., Cambot, M., Moreau, K., Lenoir, G.M., Joulin, V., Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival. Cancer Res. 66 (2006), 5287–5294.
    • (2006) Cancer Res. , vol.66 , pp. 5287-5294
    • Chajès, V.1    Cambot, M.2    Moreau, K.3    Lenoir, G.M.4    Joulin, V.5
  • 6
    • 84907048181 scopus 로고    scopus 로고
    • AMPK reverses the mesenchymal phenotype of cancer cells by targeting the Akt-MDM2-Foxo3a signaling axis
    • Chou, C.C., Lee, K.H., Lai, I.L., Wang, D., Mo, X., Kulp, S.K., Shapiro, C.L., Chen, C.S., AMPK reverses the mesenchymal phenotype of cancer cells by targeting the Akt-MDM2-Foxo3a signaling axis. Cancer Res. 74 (2014), 4783–4795.
    • (2014) Cancer Res. , vol.74 , pp. 4783-4795
    • Chou, C.C.1    Lee, K.H.2    Lai, I.L.3    Wang, D.4    Mo, X.5    Kulp, S.K.6    Shapiro, C.L.7    Chen, C.S.8
  • 10
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
    • Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 365 (2005), 1687–1717.
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 11
    • 84861819258 scopus 로고    scopus 로고
    • Malonyl-CoA: the regulator of fatty acid synthesis and oxidation
    • Foster, D.W., Malonyl-CoA: the regulator of fatty acid synthesis and oxidation. J. Clin. Invest. 122 (2012), 1958–1959.
    • (2012) J. Clin. Invest. , vol.122 , pp. 1958-1959
    • Foster, D.W.1
  • 12
    • 80355130018 scopus 로고    scopus 로고
    • A simple hanging drop cell culture protocol for generation of 3D spheroids
    • Foty, R., A simple hanging drop cell culture protocol for generation of 3D spheroids. J. Vis. Exp., 2011, 2720.
    • (2011) J. Vis. Exp. , pp. 2720
    • Foty, R.1
  • 13
    • 84863613036 scopus 로고    scopus 로고
    • Acetyl-CoA carboxylase regulates global histone acetylation
    • Galdieri, L., Vancura, A., Acetyl-CoA carboxylase regulates global histone acetylation. J. Biol. Chem. 287 (2012), 23865–23876.
    • (2012) J. Biol. Chem. , vol.287 , pp. 23865-23876
    • Galdieri, L.1    Vancura, A.2
  • 17
    • 84862819412 scopus 로고    scopus 로고
    • Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells
    • Guo, S., Liu, M., Wang, G., Torroella-Kouri, M., Gonzalez-Perez, R.R., Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells. Biochim. Biophys. Acta 1825 (2012), 207–222.
    • (2012) Biochim. Biophys. Acta , vol.1825 , pp. 207-222
    • Guo, S.1    Liu, M.2    Wang, G.3    Torroella-Kouri, M.4    Gonzalez-Perez, R.R.5
  • 18
    • 84863763440 scopus 로고    scopus 로고
    • AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
    • Jeon, S.M., Chandel, N.S., Hay, N., AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress. Nature 485 (2012), 661–665.
    • (2012) Nature , vol.485 , pp. 661-665
    • Jeon, S.M.1    Chandel, N.S.2    Hay, N.3
  • 20
    • 14344251702 scopus 로고    scopus 로고
    • Anaerobic and aerobic enzyme activities in human skeletal muscle from children and adults
    • Kaczor, J.J., Ziolkowski, W., Popinigis, J., Tarnopolsky, M.A., Anaerobic and aerobic enzyme activities in human skeletal muscle from children and adults. Pediatr. Res. 57 (2005), 331–335.
    • (2005) Pediatr. Res. , vol.57 , pp. 331-335
    • Kaczor, J.J.1    Ziolkowski, W.2    Popinigis, J.3    Tarnopolsky, M.A.4
  • 21
    • 81855225795 scopus 로고    scopus 로고
    • Molecular mechanisms of cancer development in obesity
    • Khandekar, M.J., Cohen, P., Spiegelman, B.M., Molecular mechanisms of cancer development in obesity. Nat. Rev. Cancer 11 (2011), 886–895.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 886-895
    • Khandekar, M.J.1    Cohen, P.2    Spiegelman, B.M.3
  • 23
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • Lamouille, S., Xu, J., Derynck, R., Molecular mechanisms of epithelial-mesenchymal transition. Nat. Rev. Mol. Cell Biol. 15 (2014), 178–196.
    • (2014) Nat. Rev. Mol. Cell Biol. , vol.15 , pp. 178-196
    • Lamouille, S.1    Xu, J.2    Derynck, R.3
  • 24
    • 84952670525 scopus 로고    scopus 로고
    • LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells
    • Li, N.S., Zou, J.R., Lin, H., Ke, R., He, X.L., Xiao, L., Huang, D., Luo, L., Lv, N., Luo, Z., LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells. Tumour Biol. 37 (2016), 8249–8258.
    • (2016) Tumour Biol. , vol.37 , pp. 8249-8258
    • Li, N.S.1    Zou, J.R.2    Lin, H.3    Ke, R.4    He, X.L.5    Xiao, L.6    Huang, D.7    Luo, L.8    Lv, N.9    Luo, Z.10
  • 25
    • 84993960791 scopus 로고    scopus 로고
    • Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab
    • Luo, J., Hong, Y., Lu, Y., Qiu, S., Chaganty, B.K., Zhang, L., Wang, X., Li, Q., Fan, Z., Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab. Cancer Lett. 384 (2017), 39–49.
    • (2017) Cancer Lett. , vol.384 , pp. 39-49
    • Luo, J.1    Hong, Y.2    Lu, Y.3    Qiu, S.4    Chaganty, B.K.5    Zhang, L.6    Wang, X.7    Li, Q.8    Fan, Z.9
  • 27
    • 80052511813 scopus 로고    scopus 로고
    • The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
    • Mihaylova, M.M., Shaw, R.J., The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nat. Cell Biol. 13 (2011), 1016–1023.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 1016-1023
    • Mihaylova, M.M.1    Shaw, R.J.2
  • 28
    • 0037122766 scopus 로고    scopus 로고
    • Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
    • Minokoshi, Y., Kim, Y.B., Peroni, O.D., Fryer, L.G., Müller, C., Carling, D., Kahn, B.B., Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 415 (2002), 339–343.
    • (2002) Nature , vol.415 , pp. 339-343
    • Minokoshi, Y.1    Kim, Y.B.2    Peroni, O.D.3    Fryer, L.G.4    Müller, C.5    Carling, D.6    Kahn, B.B.7
  • 29
    • 78650969715 scopus 로고    scopus 로고
    • Effect of obesity on survival of women with breast cancer: systematic review and meta-analysis
    • Protani, M., Coory, M., Martin, J.H., Effect of obesity on survival of women with breast cancer: systematic review and meta-analysis. Breast Cancer Res. Treat. 123 (2010), 627–635.
    • (2010) Breast Cancer Res. Treat. , vol.123 , pp. 627-635
    • Protani, M.1    Coory, M.2    Martin, J.H.3
  • 30
    • 0042330251 scopus 로고    scopus 로고
    • Minireview: the adipocyte—at the crossroads of energy homeostasis, inflammation, and atherosclerosis
    • Rajala, M.W., Scherer, P.E., Minireview: the adipocyte—at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology 144 (2003), 3765–3773.
    • (2003) Endocrinology , vol.144 , pp. 3765-3773
    • Rajala, M.W.1    Scherer, P.E.2
  • 31
    • 84876936567 scopus 로고    scopus 로고
    • AMPK activation by oncogenesis is required to maintain cancer cell proliferation in astrocytic tumors
    • Ríos, M., Foretz, M., Viollet, B., Prieto, A., Fraga, M., Costoya, J.A., Señarís, R., AMPK activation by oncogenesis is required to maintain cancer cell proliferation in astrocytic tumors. Cancer Res. 73 (2013), 2628–2638.
    • (2013) Cancer Res. , vol.73 , pp. 2628-2638
    • Ríos, M.1    Foretz, M.2    Viollet, B.3    Prieto, A.4    Fraga, M.5    Costoya, J.A.6    Señarís, R.7
  • 32
    • 84988553080 scopus 로고    scopus 로고
    • The multifaceted roles of fatty acid synthesis in cancer
    • Röhrig, F., Schulze, A., The multifaceted roles of fatty acid synthesis in cancer. Nat. Rev. Cancer 16 (2016), 732–749.
    • (2016) Nat. Rev. Cancer , vol.16 , pp. 732-749
    • Röhrig, F.1    Schulze, A.2
  • 33
    • 38349117213 scopus 로고    scopus 로고
    • Retinal progenitor cells can produce restricted subsets of horizontal cells
    • Rompani, S.B., Cepko, C.L., Retinal progenitor cells can produce restricted subsets of horizontal cells. Proc. Natl. Acad. Sci. USA 105 (2008), 192–197.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 192-197
    • Rompani, S.B.1    Cepko, C.L.2
  • 34
    • 84863837081 scopus 로고    scopus 로고
    • Lipid metabolism in cancer
    • Santos, C.R., Schulze, A., Lipid metabolism in cancer. FEBS J. 279 (2012), 2610–2623.
    • (2012) FEBS J. , vol.279 , pp. 2610-2623
    • Santos, C.R.1    Schulze, A.2
  • 35
    • 33845970937 scopus 로고    scopus 로고
    • The DNA binding activities of Smad2 and Smad3 are regulated by coactivator-mediated acetylation
    • Simonsson, M., Kanduri, M., Grönroos, E., Heldin, C.H., Ericsson, J., The DNA binding activities of Smad2 and Smad3 are regulated by coactivator-mediated acetylation. J. Biol. Chem. 281 (2006), 39870–39880.
    • (2006) J. Biol. Chem. , vol.281 , pp. 39870-39880
    • Simonsson, M.1    Kanduri, M.2    Grönroos, E.3    Heldin, C.H.4    Ericsson, J.5
  • 39
    • 34547132592 scopus 로고    scopus 로고
    • Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response
    • Tu, A.W., Luo, K., Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response. J. Biol. Chem. 282 (2007), 21187–21196.
    • (2007) J. Biol. Chem. , vol.282 , pp. 21187-21196
    • Tu, A.W.1    Luo, K.2
  • 40
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: the metabolic requirements of cell proliferation
    • Vander Heiden, M.G., Cantley, L.C., Thompson, C.B., Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324 (2009), 1029–1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 41
    • 84897543202 scopus 로고    scopus 로고
    • A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies
    • Wang, C.C., Bajikar, S.S., Jamal, L., Atkins, K.A., Janes, K.A., A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies. Nat. Cell Biol. 16 (2014), 345–356.
    • (2014) Nat. Cell Biol. , vol.16 , pp. 345-356
    • Wang, C.C.1    Bajikar, S.S.2    Jamal, L.3    Atkins, K.A.4    Janes, K.A.5
  • 42
    • 84975726280 scopus 로고    scopus 로고
    • Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients
    • Wang, M.D., Wu, H., Fu, G.B., Zhang, H.L., Zhou, X., Tang, L., Dong, L.W., Qin, C.J., Huang, S., Zhao, L.H., et al. Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients. Hepatology 63 (2016), 1272–1286.
    • (2016) Hepatology , vol.63 , pp. 1272-1286
    • Wang, M.D.1    Wu, H.2    Fu, G.B.3    Zhang, H.L.4    Zhou, X.5    Tang, L.6    Dong, L.W.7    Qin, C.J.8    Huang, S.9    Zhao, L.H.10
  • 45
    • 84878249924 scopus 로고    scopus 로고
    • Role of AMPK in UVB-induced DNA damage repair and growth control
    • Wu, C.L., Qiang, L., Han, W., Ming, M., Viollet, B., He, Y.Y., Role of AMPK in UVB-induced DNA damage repair and growth control. Oncogene 32 (2013), 2682–2689.
    • (2013) Oncogene , vol.32 , pp. 2682-2689
    • Wu, C.L.1    Qiang, L.2    Han, W.3    Ming, M.4    Viollet, B.5    He, Y.Y.6
  • 46
    • 84991672308 scopus 로고    scopus 로고
    • Obesity and breast cancer: risk, outcomes, and future considerations
    • Yung, R.L., Ligibel, J.A., Obesity and breast cancer: risk, outcomes, and future considerations. Clin. Adv. Hematol. Oncol. 14 (2016), 790–797.
    • (2016) Clin. Adv. Hematol. Oncol. , vol.14 , pp. 790-797
    • Yung, R.L.1    Ligibel, J.A.2
  • 47
    • 84864858864 scopus 로고    scopus 로고
    • ATP-citrate lyase: a key player in cancer metabolism
    • Zaidi, N., Swinnen, J.V., Smans, K., ATP-citrate lyase: a key player in cancer metabolism. Cancer Res. 72 (2012), 3709–3714.
    • (2012) Cancer Res. , vol.72 , pp. 3709-3714
    • Zaidi, N.1    Swinnen, J.V.2    Smans, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.