Metabolism: AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

Science

Volumn 351, Issue 6270, 2016, Pages 275-281

  Toyama, Erin Quan ^a   Herzig, Sébastien ^a   Courchet, Julien ^b   Lewis, Tommy L ^b   Losón, Oliver C ^c   Hellberg, Kristina ^a   Young, Nathan P ^a   Chen, Hsiuchen ^c   Polleux, Franck ^b   Chan, David C ^c   Shaw, Reuben J ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c California Institute of Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRP1 PROTEIN; GUANOSINE TRIPHOSPHATASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MEMBRANE PROTEIN; MEMBRANE RECEPTOR; MITOCHONDRIAL FISSION FACTOR; UNCLASSIFIED DRUG; ADENOSINE PHOSPHATE; CACTINOMYCIN; DACTINOMYCIN; DNM1L PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; MITOCHONDRIAL PROTEIN; ROTENONE;

BIOENERGETICS; ENZYME ACTIVITY; INHIBITOR; METABOLISM; MITOCHONDRION; MUTATION; PROTEIN;

ALLELE; ARTICLE; CELLULAR PARAMETERS; CONTROLLED STUDY; CYTOPLASM; EMBRYO; ENERGY; HUMAN; HUMAN CELL; MITOCHONDRIAL FISSION; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RESPIRATORY CHAIN; STRESS; ANALOGS AND DERIVATIVES; CHEMISTRY; DRUG EFFECTS; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; METABOLISM; MITOCHONDRIAL DYNAMICS; MITOCHONDRION; MOLECULAR GENETICS; PHYSIOLOGICAL STRESS; PHYSIOLOGY; PROTEIN MOTIF; TUMOR CELL LINE;

ADENOSINE MONOPHOSPHATE; AMINO ACID MOTIFS; AMP-ACTIVATED PROTEIN KINASES; CELL LINE, TUMOR; CYTOPLASM; DACTINOMYCIN; ENERGY METABOLISM; ENZYME ACTIVATION; GTP PHOSPHOHYDROLASES; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; ROTENONE; STRESS, PHYSIOLOGICAL;

EID: 84954318420     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aab4138     Document Type: Article

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