-
1
-
-
17844394391
-
Mitogen-activated protein kinase activation in UV-induced signal transduction
-
Bode AM, Dong Z. Mitogen-activated protein kinase activation in UV-induced signal transduction. Sci STKE 2003; 2003: RE2.
-
(2003)
Sci STKE
, vol.2003
-
-
Bode, A.M.1
Dong, Z.2
-
2
-
-
0345862188
-
Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling
-
Bowden GT. Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling. Nat Rev Cancer 2004; 4: 23-35.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 23-35
-
-
Bowden, G.T.1
-
3
-
-
0031896909
-
Clinical and histologic trends of melanoma
-
Johnson TM, Dolan OM, Hamilton TA, Lu MC, Swanson NA, Lowe L. Clinical and histologic trends of melanoma. J Am Acad Dermatol 1998; 38: 681-686.
-
(1998)
J Am Acad Dermatol
, vol.38
, pp. 681-686
-
-
Johnson, T.M.1
Dolan, O.M.2
Hamilton, T.A.3
Lu, M.C.4
Swanson, N.A.5
Lowe, L.6
-
4
-
-
0024263363
-
Cyclobutane-type pyrimidine photodimer formation and induction of ornithine decarboxylase in human skin fibroblasts after UV irradiation
-
Niggli HJ, Rothlisberger R. Cyclobutane-type pyrimidine photodimer formation and induction of ornithine decarboxylase in human skin fibroblasts after UV irradiation. J Invest Dermatol 1988; 91: 579-584.
-
(1988)
J Invest Dermatol
, vol.91
, pp. 579-584
-
-
Niggli, H.J.1
Rothlisberger, R.2
-
5
-
-
0025853815
-
Induction, repair and accumulation of thymine dimers in the skin of UV-B-irradiated hairless mice
-
Vink AA, Berg RJ, de Gruijl FR, Roza L, Baan RA. Induction, repair and accumulation of thymine dimers in the skin of UV-B-irradiated hairless mice. Carcinogenesis 1991; 12: 861-864.
-
(1991)
Carcinogenesis
, vol.12
, pp. 861-864
-
-
Vink, A.A.1
Berg, R.J.2
De Gruijl, F.R.3
Roza, L.4
Baan, R.A.5
-
6
-
-
27844470581
-
Transcriptome analysis reveals cyclobutane pyrimidine dimers as a major source of UV-induced DNA breaks
-
Garinis GA, Mitchell JR, Moorhouse MJ, Hanada K, de Waard H, Vandeputte D et al. Transcriptome analysis reveals cyclobutane pyrimidine dimers as a major source of UV-induced DNA breaks. EMBO J 2005; 24: 3952-3962.
-
(2005)
EMBO J
, vol.24
, pp. 3952-3962
-
-
Garinis, G.A.1
Mitchell, J.R.2
Moorhouse, M.J.3
Hanada, K.4
De Waard, H.5
Vandeputte, D.6
-
7
-
-
0034612505
-
Elevated UV-B radiation reduces genome stability in plants
-
Ries G, Heller W, Puchta H, Sandermann H, Seidlitz HK, Hohn B. Elevated UV-B radiation reduces genome stability in plants. Nature 2000; 406: 98-101.
-
(2000)
Nature
, vol.406
, pp. 98-101
-
-
Ries, G.1
Heller, W.2
Puchta, H.3
Sandermann, H.4
Seidlitz, H.K.5
Hohn, B.6
-
8
-
-
0031022619
-
Sunlight and skin cancer: Another link revealed
-
Kraemer KH. Sunlight and skin cancer: another link revealed. Proc Natl Acad Sci USA 1997; 94: 11-14.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 11-14
-
-
Kraemer, K.H.1
-
9
-
-
19944431173
-
Powerful skin cancer protection by a CPD-photolyase transgene
-
Jans J, Schul W, Sert YG, Rijksen Y, Rebel H, Eker AP et al. Powerful skin cancer protection by a CPD-photolyase transgene. Curr Biol 2005; 15: 105-115.
-
(2005)
Curr Biol
, vol.15
, pp. 105-115
-
-
Jans, J.1
Schul, W.2
Sert, Y.G.3
Rijksen, Y.4
Rebel, H.5
Eker, A.P.6
-
10
-
-
0035977005
-
Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cells
-
You YH, Lee DH, Yoon JH, Nakajima S, Yasui A, Pfeifer GP. Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cells. J Biol Chem 2001; 276: 44688-44694.
-
(2001)
J Biol Chem
, vol.276
, pp. 44688-44694
-
-
You, Y.H.1
Lee, D.H.2
Yoon, J.H.3
Nakajima, S.4
Yasui, A.5
Pfeifer, G.P.6
-
11
-
-
0021282448
-
DNA repair protects against cutaneous and internal neoplasia: Evidence from xeroderma pigmentosum
-
Kraemer KH, Lee MM, Scotto J. DNA repair protects against cutaneous and internal neoplasia: evidence from xeroderma pigmentosum. Carcinogenesis 1984; 5: 511-514.
-
(1984)
Carcinogenesis
, vol.5
, pp. 511-514
-
-
Kraemer, K.H.1
Lee, M.M.2
Scotto, J.3
-
12
-
-
0028110878
-
The role of sunlight and DNA repair in melanoma and nonmelanoma skin cancer. The xeroderma pigmentosum paradigm
-
Kraemer KH, Lee MM, Andrews AD, Lambert WC. The role of sunlight and DNA repair in melanoma and nonmelanoma skin cancer. The xeroderma pigmentosum paradigm. Arch Dermatol 1994; 130: 1018-1021.
-
(1994)
Arch Dermatol
, vol.130
, pp. 1018-1021
-
-
Kraemer, K.H.1
Lee, M.M.2
Andrews, A.D.3
Lambert, W.C.4
-
13
-
-
33745515754
-
Chronic UVA irradiation of human HaCaT keratinocytes induces malignant transformation associated with acquired apoptotic resistance
-
He YY, Pi J, Huang JL, Diwan BA, Waalkes MP, Chignell CF. Chronic UVA irradiation of human HaCaT keratinocytes induces malignant transformation associated with acquired apoptotic resistance. Oncogene 2006; 25: 3680-3688.
-
(2006)
Oncogene
, vol.25
, pp. 3680-3688
-
-
He, Y.Y.1
Pi, J.2
Huang, J.L.3
Diwan, B.A.4
Waalkes, M.P.5
Chignell, C.F.6
-
14
-
-
47549111121
-
UVA radiation causes DNA strand breaks, chromosomal aberrations and tumorigenic transformation in HaCaT skin keratinocytes
-
Wischermann K, Popp S, Moshir S, Scharfetter-Kochanek K, Wlaschek M, de Gruijl F et al. UVA radiation causes DNA strand breaks, chromosomal aberrations and tumorigenic transformation in HaCaT skin keratinocytes. Oncogene 2008; 27: 4269-4280.
-
(2008)
Oncogene
, vol.27
, pp. 4269-4280
-
-
Wischermann, K.1
Popp, S.2
Moshir, S.3
Scharfetter-Kochanek, K.4
Wlaschek, M.5
De Gruijl, F.6
-
15
-
-
0032134423
-
Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair
-
Sugasawa K, Ng JM, Masutani C, Iwai S, van der Spek PJ, Eker AP et al. Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair. Mol Cell 1998; 2: 223-232.
-
(1998)
Mol Cell
, vol.2
, pp. 223-232
-
-
Sugasawa, K.1
Ng, J.M.2
Masutani, C.3
Iwai, S.4
Van Der Spek, P.J.5
Eker, A.P.6
-
16
-
-
33751345828
-
UV-induced ubiquitylation of XPC complex, the UV-DDB-ubiquitin ligase complex, and DNA repair
-
Sugasawa K. UV-induced ubiquitylation of XPC complex, the UV-DDB-ubiquitin ligase complex, and DNA repair. J Mol Histol 2006; 37: 189-202.
-
(2006)
J Mol Histol
, vol.37
, pp. 189-202
-
-
Sugasawa, K.1
-
17
-
-
21744452376
-
Cancer in xeroderma pigmentosum and related disorders of DNA repair
-
Cleaver JE. Cancer in xeroderma pigmentosum and related disorders of DNA repair. Nat Rev Cancer 2005; 5: 564-573.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 564-573
-
-
Cleaver, J.E.1
-
18
-
-
70350065725
-
Disorders of nucleotide excision repair: The genetic and molecular basis of heterogeneity
-
Cleaver JE, Lam ET, Revet I. Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity. Nat Rev Genet 2009; 10: 756-768.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 756-768
-
-
Cleaver, J.E.1
Lam, E.T.2
Revet, I.3
-
19
-
-
80052511813
-
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
-
Mihaylova MM, Shaw RJ. The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nat Cell Biol 2011; 13: 1016-1023.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1016-1023
-
-
Mihaylova, M.M.1
Shaw, R.J.2
-
20
-
-
12844281251
-
AMPK, the metabolic syndrome and cancer
-
Luo Z, Saha AK, Xiang X, NB Ruderman. AMPK, the metabolic syndrome and cancer. Trends Pharmacol Sci 2005; 26: 69-76.
-
(2005)
Trends Pharmacol Sci
, vol.26
, pp. 69-76
-
-
Luo, Z.1
Saha, A.K.2
Xiang, X.3
Ruderman, N.B.4
-
21
-
-
77949462458
-
AMPK as a metabolic tumor suppressor: Control of metabolism and cell growth
-
Luo Z, Zang M, Guo W. AMPK as a metabolic tumor suppressor: control of metabolism and cell growth. Future Oncol 2010; 6: 457-470.
-
(2010)
Future Oncol
, vol.6
, pp. 457-470
-
-
Luo, Z.1
Zang, M.2
Guo, W.3
-
22
-
-
20844449238
-
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
-
Jones RG, Plas DR, Kubek S, Buzzai M, Mu J, Xu Y et al. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell 2005; 18: 283-293.
-
(2005)
Mol Cell
, vol.18
, pp. 283-293
-
-
Jones, R.G.1
Plas, D.R.2
Kubek, S.3
Buzzai, M.4
Mu, J.5
Xu, Y.6
-
23
-
-
64849110053
-
Stabilization and activation of p53 downregulates mTOR signaling through AMPK in mantle cell lymphoma
-
Drakos E, Atsaves V, Li J, Leventaki V, Andreeff M, Medeiros LJ et al. Stabilization and activation of p53 downregulates mTOR signaling through AMPK in mantle cell lymphoma. Leukemia 2009; 23: 784-790.
-
(2009)
Leukemia
, vol.23
, pp. 784-790
-
-
Drakos, E.1
Atsaves, V.2
Li, J.3
Leventaki, V.4
Andreeff, M.5
Medeiros, L.J.6
-
24
-
-
44349184864
-
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
-
Fu X, Wan S, Lyu YL, Liu LF, Qi H. Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation. PLoS One 2008; 3 e2009.
-
(2008)
PLoS One
, vol.3
-
-
Fu, X.1
Wan, S.2
Lyu, Y.L.3
Liu, L.F.4
Qi, H.5
-
25
-
-
60449089649
-
Medical management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy: A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes
-
Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R et al. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2009; 32: 193-203.
-
(2009)
Diabetes Care
, vol.32
, pp. 193-203
-
-
Nathan, D.M.1
Buse, J.B.2
Davidson, M.B.3
Ferrannini, E.4
Holman, R.R.5
Sherwin, R.6
-
26
-
-
77954933558
-
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
-
Foretz M, Hebrard S, Leclerc J, Zarrinpashneh E, Soty M, Mithieux G et al. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state. J Clin Invest 2010; 120: 2355-2369.
-
(2010)
J Clin Invest
, vol.120
, pp. 2355-2369
-
-
Foretz, M.1
Hebrard, S.2
Leclerc, J.3
Zarrinpashneh, E.4
Soty, M.5
Mithieux, G.6
-
27
-
-
77954964776
-
An energetic tale of AMPK-independent effects of met-formin
-
Miller RA, Birnbaum MJ. An energetic tale of AMPK-independent effects of met-formin. J Clin Invest 2010; 120: 2267-2270.
-
(2010)
J Clin Invest
, vol.120
, pp. 2267-2270
-
-
Miller, R.A.1
Birnbaum, M.J.2
-
28
-
-
77956401999
-
Metformin and other biguanides in oncology: Advancing the research agenda
-
Pollak M. Metformin and other biguanides in oncology: advancing the research agenda. Cancer Prev Res (Phila) 2010; 3: 1060-1065.
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 1060-1065
-
-
Pollak, M.1
-
30
-
-
69149097363
-
The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis
-
Guo D, Hildebrandt IJ, Prins RM, Soto H, Mazzotta MM, Dang J et al. The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis. Proc Natl Acad Sci USA 2009; 106: 12932-12937.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 12932-12937
-
-
Guo, D.1
Hildebrandt, I.J.2
Prins, R.M.3
Soto, H.4
Mazzotta, M.M.5
Dang, J.6
-
31
-
-
77954761710
-
AMP-activated kinase (AMPK)-generated signals in malignant melanoma cell growth and survival
-
Woodard J, Platanias LC. AMP-activated kinase (AMPK)-generated signals in malignant melanoma cell growth and survival. Biochem Biophys Res Commun 2010; 398: 135-139.
-
(2010)
Biochem Biophys Res Commun
, vol.398
, pp. 135-139
-
-
Woodard, J.1
Platanias, L.C.2
-
32
-
-
33748561175
-
AMPK regulation of the growth of cultured human keratinocytes
-
Saha AK, Persons K, Safer JD, Luo Z, Holick MF, Ruderman NB. AMPK regulation of the growth of cultured human keratinocytes. Biochem Biophys Res Commun 2006; 349: 519-524.
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 519-524
-
-
Saha, A.K.1
Persons, K.2
Safer, J.D.3
Luo, Z.4
Holick, M.F.5
Ruderman, N.B.6
-
33
-
-
78651105018
-
Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C
-
Ming M, Shea CR, Guo X, Li X, Soltani K, Han W et al. Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C. Proc Natl Acad Sci USA 2010; 107: 22623-22628.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 22623-22628
-
-
Ming, M.1
Shea, C.R.2
Guo, X.3
Li, X.4
Soltani, K.5
Han, W.6
-
34
-
-
79960962657
-
PTEN positively regulates UVB-induced DNA damage repair
-
Ming M, Feng L, Shea CR, Soltani K, Zhao B, Han W et al. PTEN positively regulates UVB-induced DNA damage repair. Cancer Res 2011; 71: 5287-5295.
-
(2011)
Cancer Res
, vol.71
, pp. 5287-5295
-
-
Ming, M.1
Feng, L.2
Shea, C.R.3
Soltani, K.4
Zhao, B.5
Han, W.6
-
35
-
-
56749159779
-
UVB irradiation regulates Cox-2 mRNA stability through AMPK and HuR in human keratinocytes
-
Zhang J, Bowden GT. UVB irradiation regulates Cox-2 mRNA stability through AMPK and HuR in human keratinocytes. Mol Carcinog 2008; 47: 974-983.
-
(2008)
Mol Carcinog
, vol.47
, pp. 974-983
-
-
Zhang, J.1
Bowden, G.T.2
-
36
-
-
0035374673
-
Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1-and epidermal growth factor-dependent extracellular signal-regulated kinase pathway
-
Kim J, Yoon MY, Choi SL, Kang I, Kim SS, Kim YS et al. Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1-and epidermal growth factor-dependent extracellular signal-regulated kinase pathway. J Biol Chem 2001; 276: 19102-19110.
-
(2001)
J Biol Chem
, vol.276
, pp. 19102-19110
-
-
Kim, J.1
Yoon, M.Y.2
Choi, S.L.3
Kang, I.4
Kim, S.S.5
Kim, Y.S.6
-
37
-
-
39549087890
-
Inhibitory crosstalk between ERK and AMPK in the growth and proliferation of cardiac fibroblasts
-
Du J, Guan T, Zhang H, Xia Y, Liu F, Zhang Y. Inhibitory crosstalk between ERK and AMPK in the growth and proliferation of cardiac fibroblasts. Biochem Biophys Res Commun 2008; 368: 402-407.
-
(2008)
Biochem Biophys Res Commun
, vol.368
, pp. 402-407
-
-
Du, J.1
Guan, T.2
Zhang, H.3
Xia, Y.4
Liu, F.5
Zhang, Y.6
-
38
-
-
69249153394
-
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1
-
Wang J, Whiteman MW, Lian H, Wang G, Singh A, Huang D et al. A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1. J Biol Chem 2009; 284: 21412-21424.
-
(2009)
J Biol Chem
, vol.284
, pp. 21412-21424
-
-
Wang, J.1
Whiteman, M.W.2
Lian, H.3
Wang, G.4
Singh, A.5
Huang, D.6
-
39
-
-
67749111502
-
The LKB1-AMPK pathway: Metabolism and growth control in tumour suppression
-
Shackelford DB, Shaw RJ. The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat Rev Cancer 2009; 9: 563-575.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 563-575
-
-
Shackelford, D.B.1
Shaw, R.J.2
-
40
-
-
78549283186
-
The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation
-
Green AS, Chapuis N, Maciel TT, Willems L, Lambert M, Arnoult C et al. The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation. Blood 2010; 116: 4262-4273.
-
(2010)
Blood
, vol.116
, pp. 4262-4273
-
-
Green, A.S.1
Chapuis, N.2
MacIel, T.T.3
Willems, L.4
Lambert, M.5
Arnoult, C.6
-
41
-
-
79959764729
-
Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1
-
Ben Sahra I, Regazzetti C, Robert G, Laurent K, Le Marchand-Brustel Y, Auberger P et al. Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1. Cancer Res 2011; 71: 4366-4372.
-
(2011)
Cancer Res
, vol.71
, pp. 4366-4372
-
-
Ben Sahra, I.1
Regazzetti, C.2
Robert, G.3
Laurent, K.4
Le Marchand-Brustel, Y.5
Auberger, P.6
-
42
-
-
33745840203
-
5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments
-
Laderoute KR, Amin K, Calaoagan JM, Knapp M, Le T, Orduna J et al. 5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments. Mol Cell Biol 2006; 26: 5336-5347.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 5336-5347
-
-
Laderoute, K.R.1
Amin, K.2
Calaoagan, J.M.3
Knapp, M.4
Le, T.5
Orduna, J.6
-
43
-
-
75749135291
-
UVB-induced ERK/AKT-dependent PTEN suppression promotes survival of epidermal keratino-cytes
-
Ming M, Han W, Maddox J, Soltani K, Shea CR, Freeman DM et al. UVB-induced ERK/AKT-dependent PTEN suppression promotes survival of epidermal keratino-cytes. Oncogene 2010; 29: 492-502.
-
(2010)
Oncogene
, vol.29
, pp. 492-502
-
-
Ming, M.1
Han, W.2
Maddox, J.3
Soltani, K.4
Shea, C.R.5
Freeman, D.M.6
-
44
-
-
79959543115
-
Caffeine promotes UVB-induced apoptosis in human keratinocytes without complete DNA repair
-
Han W, Ming M, He YY. Caffeine promotes UVB-induced apoptosis in human keratinocytes without complete DNA repair. J Biol Chem 2011; 286: 22825-22832.
-
(2011)
J Biol Chem
, vol.286
, pp. 22825-22832
-
-
Han, W.1
Ming, M.2
He, Y.Y.3
-
45
-
-
0035675867
-
Nucleotide excision repair genes are upregulated by low-dose artificial ultraviolet B: Evidence of a photoprotective SOS response?
-
Maeda T, Chua PP, Chong MT, Sim AB, Nikaido O, Tron VA. Nucleotide excision repair genes are upregulated by low-dose artificial ultraviolet B: evidence of a photoprotective SOS response? J Invest Dermatol 2001; 117: 1490-1497.
-
(2001)
J Invest Dermatol
, vol.117
, pp. 1490-1497
-
-
Maeda, T.1
Chua, P.P.2
Chong, M.T.3
Sim, A.B.4
Nikaido, O.5
Tron, V.A.6
|