메뉴 건너뛰기




Volumn 32, Issue 21, 2013, Pages 2682-2689

Role of AMPK in UVB-induced DNA damage repair and growth control

Author keywords

AMPK; DNA repair; ERK; tumorigenesis; UVB; XPC

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; METFORMIN; MITOGEN ACTIVATED PROTEIN KINASE; XERODERMA PIGMENTOSUM GROUP C PROTEIN;

EID: 84878249924     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.279     Document Type: Article
Times cited : (87)

References (45)
  • 1
    • 17844394391 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase activation in UV-induced signal transduction
    • Bode AM, Dong Z. Mitogen-activated protein kinase activation in UV-induced signal transduction. Sci STKE 2003; 2003: RE2.
    • (2003) Sci STKE , vol.2003
    • Bode, A.M.1    Dong, Z.2
  • 2
    • 0345862188 scopus 로고    scopus 로고
    • Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling
    • Bowden GT. Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling. Nat Rev Cancer 2004; 4: 23-35.
    • (2004) Nat Rev Cancer , vol.4 , pp. 23-35
    • Bowden, G.T.1
  • 4
    • 0024263363 scopus 로고
    • Cyclobutane-type pyrimidine photodimer formation and induction of ornithine decarboxylase in human skin fibroblasts after UV irradiation
    • Niggli HJ, Rothlisberger R. Cyclobutane-type pyrimidine photodimer formation and induction of ornithine decarboxylase in human skin fibroblasts after UV irradiation. J Invest Dermatol 1988; 91: 579-584.
    • (1988) J Invest Dermatol , vol.91 , pp. 579-584
    • Niggli, H.J.1    Rothlisberger, R.2
  • 5
    • 0025853815 scopus 로고
    • Induction, repair and accumulation of thymine dimers in the skin of UV-B-irradiated hairless mice
    • Vink AA, Berg RJ, de Gruijl FR, Roza L, Baan RA. Induction, repair and accumulation of thymine dimers in the skin of UV-B-irradiated hairless mice. Carcinogenesis 1991; 12: 861-864.
    • (1991) Carcinogenesis , vol.12 , pp. 861-864
    • Vink, A.A.1    Berg, R.J.2    De Gruijl, F.R.3    Roza, L.4    Baan, R.A.5
  • 6
    • 27844470581 scopus 로고    scopus 로고
    • Transcriptome analysis reveals cyclobutane pyrimidine dimers as a major source of UV-induced DNA breaks
    • Garinis GA, Mitchell JR, Moorhouse MJ, Hanada K, de Waard H, Vandeputte D et al. Transcriptome analysis reveals cyclobutane pyrimidine dimers as a major source of UV-induced DNA breaks. EMBO J 2005; 24: 3952-3962.
    • (2005) EMBO J , vol.24 , pp. 3952-3962
    • Garinis, G.A.1    Mitchell, J.R.2    Moorhouse, M.J.3    Hanada, K.4    De Waard, H.5    Vandeputte, D.6
  • 8
    • 0031022619 scopus 로고    scopus 로고
    • Sunlight and skin cancer: Another link revealed
    • Kraemer KH. Sunlight and skin cancer: another link revealed. Proc Natl Acad Sci USA 1997; 94: 11-14.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 11-14
    • Kraemer, K.H.1
  • 9
  • 10
    • 0035977005 scopus 로고    scopus 로고
    • Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cells
    • You YH, Lee DH, Yoon JH, Nakajima S, Yasui A, Pfeifer GP. Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cells. J Biol Chem 2001; 276: 44688-44694.
    • (2001) J Biol Chem , vol.276 , pp. 44688-44694
    • You, Y.H.1    Lee, D.H.2    Yoon, J.H.3    Nakajima, S.4    Yasui, A.5    Pfeifer, G.P.6
  • 11
    • 0021282448 scopus 로고
    • DNA repair protects against cutaneous and internal neoplasia: Evidence from xeroderma pigmentosum
    • Kraemer KH, Lee MM, Scotto J. DNA repair protects against cutaneous and internal neoplasia: evidence from xeroderma pigmentosum. Carcinogenesis 1984; 5: 511-514.
    • (1984) Carcinogenesis , vol.5 , pp. 511-514
    • Kraemer, K.H.1    Lee, M.M.2    Scotto, J.3
  • 12
    • 0028110878 scopus 로고
    • The role of sunlight and DNA repair in melanoma and nonmelanoma skin cancer. The xeroderma pigmentosum paradigm
    • Kraemer KH, Lee MM, Andrews AD, Lambert WC. The role of sunlight and DNA repair in melanoma and nonmelanoma skin cancer. The xeroderma pigmentosum paradigm. Arch Dermatol 1994; 130: 1018-1021.
    • (1994) Arch Dermatol , vol.130 , pp. 1018-1021
    • Kraemer, K.H.1    Lee, M.M.2    Andrews, A.D.3    Lambert, W.C.4
  • 13
    • 33745515754 scopus 로고    scopus 로고
    • Chronic UVA irradiation of human HaCaT keratinocytes induces malignant transformation associated with acquired apoptotic resistance
    • He YY, Pi J, Huang JL, Diwan BA, Waalkes MP, Chignell CF. Chronic UVA irradiation of human HaCaT keratinocytes induces malignant transformation associated with acquired apoptotic resistance. Oncogene 2006; 25: 3680-3688.
    • (2006) Oncogene , vol.25 , pp. 3680-3688
    • He, Y.Y.1    Pi, J.2    Huang, J.L.3    Diwan, B.A.4    Waalkes, M.P.5    Chignell, C.F.6
  • 14
    • 47549111121 scopus 로고    scopus 로고
    • UVA radiation causes DNA strand breaks, chromosomal aberrations and tumorigenic transformation in HaCaT skin keratinocytes
    • Wischermann K, Popp S, Moshir S, Scharfetter-Kochanek K, Wlaschek M, de Gruijl F et al. UVA radiation causes DNA strand breaks, chromosomal aberrations and tumorigenic transformation in HaCaT skin keratinocytes. Oncogene 2008; 27: 4269-4280.
    • (2008) Oncogene , vol.27 , pp. 4269-4280
    • Wischermann, K.1    Popp, S.2    Moshir, S.3    Scharfetter-Kochanek, K.4    Wlaschek, M.5    De Gruijl, F.6
  • 15
    • 0032134423 scopus 로고    scopus 로고
    • Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair
    • Sugasawa K, Ng JM, Masutani C, Iwai S, van der Spek PJ, Eker AP et al. Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair. Mol Cell 1998; 2: 223-232.
    • (1998) Mol Cell , vol.2 , pp. 223-232
    • Sugasawa, K.1    Ng, J.M.2    Masutani, C.3    Iwai, S.4    Van Der Spek, P.J.5    Eker, A.P.6
  • 16
    • 33751345828 scopus 로고    scopus 로고
    • UV-induced ubiquitylation of XPC complex, the UV-DDB-ubiquitin ligase complex, and DNA repair
    • Sugasawa K. UV-induced ubiquitylation of XPC complex, the UV-DDB-ubiquitin ligase complex, and DNA repair. J Mol Histol 2006; 37: 189-202.
    • (2006) J Mol Histol , vol.37 , pp. 189-202
    • Sugasawa, K.1
  • 17
    • 21744452376 scopus 로고    scopus 로고
    • Cancer in xeroderma pigmentosum and related disorders of DNA repair
    • Cleaver JE. Cancer in xeroderma pigmentosum and related disorders of DNA repair. Nat Rev Cancer 2005; 5: 564-573.
    • (2005) Nat Rev Cancer , vol.5 , pp. 564-573
    • Cleaver, J.E.1
  • 18
    • 70350065725 scopus 로고    scopus 로고
    • Disorders of nucleotide excision repair: The genetic and molecular basis of heterogeneity
    • Cleaver JE, Lam ET, Revet I. Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity. Nat Rev Genet 2009; 10: 756-768.
    • (2009) Nat Rev Genet , vol.10 , pp. 756-768
    • Cleaver, J.E.1    Lam, E.T.2    Revet, I.3
  • 19
    • 80052511813 scopus 로고    scopus 로고
    • The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
    • Mihaylova MM, Shaw RJ. The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nat Cell Biol 2011; 13: 1016-1023.
    • (2011) Nat Cell Biol , vol.13 , pp. 1016-1023
    • Mihaylova, M.M.1    Shaw, R.J.2
  • 21
    • 77949462458 scopus 로고    scopus 로고
    • AMPK as a metabolic tumor suppressor: Control of metabolism and cell growth
    • Luo Z, Zang M, Guo W. AMPK as a metabolic tumor suppressor: control of metabolism and cell growth. Future Oncol 2010; 6: 457-470.
    • (2010) Future Oncol , vol.6 , pp. 457-470
    • Luo, Z.1    Zang, M.2    Guo, W.3
  • 22
    • 20844449238 scopus 로고    scopus 로고
    • AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
    • Jones RG, Plas DR, Kubek S, Buzzai M, Mu J, Xu Y et al. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell 2005; 18: 283-293.
    • (2005) Mol Cell , vol.18 , pp. 283-293
    • Jones, R.G.1    Plas, D.R.2    Kubek, S.3    Buzzai, M.4    Mu, J.5    Xu, Y.6
  • 23
    • 64849110053 scopus 로고    scopus 로고
    • Stabilization and activation of p53 downregulates mTOR signaling through AMPK in mantle cell lymphoma
    • Drakos E, Atsaves V, Li J, Leventaki V, Andreeff M, Medeiros LJ et al. Stabilization and activation of p53 downregulates mTOR signaling through AMPK in mantle cell lymphoma. Leukemia 2009; 23: 784-790.
    • (2009) Leukemia , vol.23 , pp. 784-790
    • Drakos, E.1    Atsaves, V.2    Li, J.3    Leventaki, V.4    Andreeff, M.5    Medeiros, L.J.6
  • 24
    • 44349184864 scopus 로고    scopus 로고
    • Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
    • Fu X, Wan S, Lyu YL, Liu LF, Qi H. Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation. PLoS One 2008; 3 e2009.
    • (2008) PLoS One , vol.3
    • Fu, X.1    Wan, S.2    Lyu, Y.L.3    Liu, L.F.4    Qi, H.5
  • 25
    • 60449089649 scopus 로고    scopus 로고
    • Medical management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy: A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes
    • Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R et al. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2009; 32: 193-203.
    • (2009) Diabetes Care , vol.32 , pp. 193-203
    • Nathan, D.M.1    Buse, J.B.2    Davidson, M.B.3    Ferrannini, E.4    Holman, R.R.5    Sherwin, R.6
  • 26
    • 77954933558 scopus 로고    scopus 로고
    • Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
    • Foretz M, Hebrard S, Leclerc J, Zarrinpashneh E, Soty M, Mithieux G et al. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state. J Clin Invest 2010; 120: 2355-2369.
    • (2010) J Clin Invest , vol.120 , pp. 2355-2369
    • Foretz, M.1    Hebrard, S.2    Leclerc, J.3    Zarrinpashneh, E.4    Soty, M.5    Mithieux, G.6
  • 27
    • 77954964776 scopus 로고    scopus 로고
    • An energetic tale of AMPK-independent effects of met-formin
    • Miller RA, Birnbaum MJ. An energetic tale of AMPK-independent effects of met-formin. J Clin Invest 2010; 120: 2267-2270.
    • (2010) J Clin Invest , vol.120 , pp. 2267-2270
    • Miller, R.A.1    Birnbaum, M.J.2
  • 28
    • 77956401999 scopus 로고    scopus 로고
    • Metformin and other biguanides in oncology: Advancing the research agenda
    • Pollak M. Metformin and other biguanides in oncology: advancing the research agenda. Cancer Prev Res (Phila) 2010; 3: 1060-1065.
    • (2010) Cancer Prev Res (Phila) , vol.3 , pp. 1060-1065
    • Pollak, M.1
  • 29
    • 77952116629 scopus 로고    scopus 로고
    • Metformin in cancer therapy: A new perspective for an old antidiabetic drug?
    • Ben Sahra I, Le Marchand-Brustel Y, Tanti JF, Bost F. Metformin in cancer therapy: a new perspective for an old antidiabetic drug? Mol Cancer Ther 2010; 9: 1092-1099.
    • (2010) Mol Cancer Ther , vol.9 , pp. 1092-1099
    • Ben Sahra, I.1    Le Marchand-Brustel, Y.2    Tanti, J.F.3    Bost, F.4
  • 30
    • 69149097363 scopus 로고    scopus 로고
    • The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis
    • Guo D, Hildebrandt IJ, Prins RM, Soto H, Mazzotta MM, Dang J et al. The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis. Proc Natl Acad Sci USA 2009; 106: 12932-12937.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 12932-12937
    • Guo, D.1    Hildebrandt, I.J.2    Prins, R.M.3    Soto, H.4    Mazzotta, M.M.5    Dang, J.6
  • 31
    • 77954761710 scopus 로고    scopus 로고
    • AMP-activated kinase (AMPK)-generated signals in malignant melanoma cell growth and survival
    • Woodard J, Platanias LC. AMP-activated kinase (AMPK)-generated signals in malignant melanoma cell growth and survival. Biochem Biophys Res Commun 2010; 398: 135-139.
    • (2010) Biochem Biophys Res Commun , vol.398 , pp. 135-139
    • Woodard, J.1    Platanias, L.C.2
  • 33
    • 78651105018 scopus 로고    scopus 로고
    • Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C
    • Ming M, Shea CR, Guo X, Li X, Soltani K, Han W et al. Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C. Proc Natl Acad Sci USA 2010; 107: 22623-22628.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 22623-22628
    • Ming, M.1    Shea, C.R.2    Guo, X.3    Li, X.4    Soltani, K.5    Han, W.6
  • 34
    • 79960962657 scopus 로고    scopus 로고
    • PTEN positively regulates UVB-induced DNA damage repair
    • Ming M, Feng L, Shea CR, Soltani K, Zhao B, Han W et al. PTEN positively regulates UVB-induced DNA damage repair. Cancer Res 2011; 71: 5287-5295.
    • (2011) Cancer Res , vol.71 , pp. 5287-5295
    • Ming, M.1    Feng, L.2    Shea, C.R.3    Soltani, K.4    Zhao, B.5    Han, W.6
  • 35
    • 56749159779 scopus 로고    scopus 로고
    • UVB irradiation regulates Cox-2 mRNA stability through AMPK and HuR in human keratinocytes
    • Zhang J, Bowden GT. UVB irradiation regulates Cox-2 mRNA stability through AMPK and HuR in human keratinocytes. Mol Carcinog 2008; 47: 974-983.
    • (2008) Mol Carcinog , vol.47 , pp. 974-983
    • Zhang, J.1    Bowden, G.T.2
  • 36
    • 0035374673 scopus 로고    scopus 로고
    • Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1-and epidermal growth factor-dependent extracellular signal-regulated kinase pathway
    • Kim J, Yoon MY, Choi SL, Kang I, Kim SS, Kim YS et al. Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1-and epidermal growth factor-dependent extracellular signal-regulated kinase pathway. J Biol Chem 2001; 276: 19102-19110.
    • (2001) J Biol Chem , vol.276 , pp. 19102-19110
    • Kim, J.1    Yoon, M.Y.2    Choi, S.L.3    Kang, I.4    Kim, S.S.5    Kim, Y.S.6
  • 37
    • 39549087890 scopus 로고    scopus 로고
    • Inhibitory crosstalk between ERK and AMPK in the growth and proliferation of cardiac fibroblasts
    • Du J, Guan T, Zhang H, Xia Y, Liu F, Zhang Y. Inhibitory crosstalk between ERK and AMPK in the growth and proliferation of cardiac fibroblasts. Biochem Biophys Res Commun 2008; 368: 402-407.
    • (2008) Biochem Biophys Res Commun , vol.368 , pp. 402-407
    • Du, J.1    Guan, T.2    Zhang, H.3    Xia, Y.4    Liu, F.5    Zhang, Y.6
  • 38
    • 69249153394 scopus 로고    scopus 로고
    • A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1
    • Wang J, Whiteman MW, Lian H, Wang G, Singh A, Huang D et al. A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1. J Biol Chem 2009; 284: 21412-21424.
    • (2009) J Biol Chem , vol.284 , pp. 21412-21424
    • Wang, J.1    Whiteman, M.W.2    Lian, H.3    Wang, G.4    Singh, A.5    Huang, D.6
  • 39
    • 67749111502 scopus 로고    scopus 로고
    • The LKB1-AMPK pathway: Metabolism and growth control in tumour suppression
    • Shackelford DB, Shaw RJ. The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat Rev Cancer 2009; 9: 563-575.
    • (2009) Nat Rev Cancer , vol.9 , pp. 563-575
    • Shackelford, D.B.1    Shaw, R.J.2
  • 40
    • 78549283186 scopus 로고    scopus 로고
    • The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation
    • Green AS, Chapuis N, Maciel TT, Willems L, Lambert M, Arnoult C et al. The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation. Blood 2010; 116: 4262-4273.
    • (2010) Blood , vol.116 , pp. 4262-4273
    • Green, A.S.1    Chapuis, N.2    MacIel, T.T.3    Willems, L.4    Lambert, M.5    Arnoult, C.6
  • 42
    • 33745840203 scopus 로고    scopus 로고
    • 5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments
    • Laderoute KR, Amin K, Calaoagan JM, Knapp M, Le T, Orduna J et al. 5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments. Mol Cell Biol 2006; 26: 5336-5347.
    • (2006) Mol Cell Biol , vol.26 , pp. 5336-5347
    • Laderoute, K.R.1    Amin, K.2    Calaoagan, J.M.3    Knapp, M.4    Le, T.5    Orduna, J.6
  • 43
    • 75749135291 scopus 로고    scopus 로고
    • UVB-induced ERK/AKT-dependent PTEN suppression promotes survival of epidermal keratino-cytes
    • Ming M, Han W, Maddox J, Soltani K, Shea CR, Freeman DM et al. UVB-induced ERK/AKT-dependent PTEN suppression promotes survival of epidermal keratino-cytes. Oncogene 2010; 29: 492-502.
    • (2010) Oncogene , vol.29 , pp. 492-502
    • Ming, M.1    Han, W.2    Maddox, J.3    Soltani, K.4    Shea, C.R.5    Freeman, D.M.6
  • 44
    • 79959543115 scopus 로고    scopus 로고
    • Caffeine promotes UVB-induced apoptosis in human keratinocytes without complete DNA repair
    • Han W, Ming M, He YY. Caffeine promotes UVB-induced apoptosis in human keratinocytes without complete DNA repair. J Biol Chem 2011; 286: 22825-22832.
    • (2011) J Biol Chem , vol.286 , pp. 22825-22832
    • Han, W.1    Ming, M.2    He, Y.Y.3
  • 45
    • 0035675867 scopus 로고    scopus 로고
    • Nucleotide excision repair genes are upregulated by low-dose artificial ultraviolet B: Evidence of a photoprotective SOS response?
    • Maeda T, Chua PP, Chong MT, Sim AB, Nikaido O, Tron VA. Nucleotide excision repair genes are upregulated by low-dose artificial ultraviolet B: evidence of a photoprotective SOS response? J Invest Dermatol 2001; 117: 1490-1497.
    • (2001) J Invest Dermatol , vol.117 , pp. 1490-1497
    • Maeda, T.1    Chua, P.P.2    Chong, M.T.3    Sim, A.B.4    Nikaido, O.5    Tron, V.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.