Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia

Nature Communications

Volumn 7, Issue , 2016, Pages

  Gao, Xue ^a,b   Lin, Shu Hai ^c,d   Ren, Feng ^a   Li, Jin Tao ^a,b   Chen, Jia Jia ^a   Yao, Chuan Bo ^a   Yang, Hong Bin ^a   Jiang, Shu Xia ^d   Yan, Guo Quan ^a   Wang, Di ^a,b   Wang, Yi ^a   Liu, Ying ^a   Cai, Zongwei ^d   Xu, Ying Ying ^a   Chen, Jing ^e   Yu, Wenqiang ^a   Yang, Peng Yuan ^a   Lei, Qun Ying ^a  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^e EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETATE COENZYME A LIGASE; ACETATE COENZYME A LIGASE 1; ACETATE COENZYME A LIGASE 2; ACETIC ACID; HISTONE H3; MESSENGER RNA; UNCLASSIFIED DRUG; VASCULOTROPIN; ACSS2 PROTEIN, HUMAN; FASN PROTEIN, HUMAN; FATTY ACID SYNTHASE; HISTONE; HISTONE ACETYLTRANSFERASE;

ACETATE; CANCER; FATTY ACID; GENE EXPRESSION; GENETIC ALGORITHM; HYPOXIA; LIPID; METABOLITE;

AMINO ACID METABOLISM; ARTICLE; CARBON SOURCE; CELL HYPOXIA; CELL METABOLISM; CELL PROLIFERATION; CELL SURVIVAL; CHOLESTEROL SYNTHESIS; CITRIC ACID CYCLE; CONTROLLED STUDY; EPIGENETICS; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; GLYCOGEN METABOLISM; GLYCOLYSIS; HEPG2 CELL LINE; HISTONE ACETYLATION; HUMAN; HUMAN CELL; LIPOGENESIS; LIVER CELL CARCINOMA; MACROMOLECULE; NUCLEAR REPROGRAMMING; PENTOSE PHOSPHATE CYCLE; PROMOTER REGION; PROTEIN EXPRESSION; RNA INTERFERENCE; SPHINGOLIPID METABOLISM; UPREGULATION; ACETYLATION; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; HEP-G2 CELL LINE; HYPOXIA; LIVER TUMOR; METABOLISM;

ACETATE-COA LIGASE; ACETATES; ACETYLATION; CARCINOMA, HEPATOCELLULAR; CELL SURVIVAL; EPIGENESIS, GENETIC; FATTY ACID SYNTHASE, TYPE I; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HISTONE ACETYLTRANSFERASES; HISTONES; HUMANS; HYPOXIA; LIPOGENESIS; LIVER NEOPLASMS;

EID: 84977119276     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms11960     Document Type: Article

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