Maternal pregravid obesity remodels the DNA methylation landscape of cord blood monocytes disrupting their inflammatory program

Journal of Immunology

Volumn 199, Issue 8, 2017, Pages 2729-2744

  Sureshchandra, Suhas ^a   Wilson, Randall M ^b   Rais, Maham ^b   Marshall, Nicole E ^c   Purnell, Jonathan Q ^d   Thornburg, Kent L ^d   Messaoudi, Ilhem ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL1 CHEMOKINE; CYTOSINE; DNA; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; RANTES; TUMOR NECROSIS FACTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TRANSCRIPTOME;

ADULT; ARTICLE; BODY MASS; CELL DIFFERENTIATION; CELL FUNCTION; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE RELEASE; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INFECTION RISK; INFLAMMATION; MATERNAL OBESITY; MONOCYTE; NEWBORN; PREDICTION; PREPREGNANCY MATERNAL OBESITY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UMBILICAL CORD BLOOD CELL; UPREGULATION; CELL CULTURE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CYTOLOGY; FETUS BLOOD; GENETIC EPIGENESIS; GENETICS; IMMUNOLOGY; METABOLISM; NECROTIZING ENTEROCOLITIS; OBESITY; PHYSIOLOGY; PREGNANCY; PRENATAL EXPOSURE; SEPSIS;

ADULT; CELLS, CULTURED; CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA METHYLATION; ENTEROCOLITIS, NECROTIZING; EPIGENESIS, GENETIC; FEMALE; FETAL BLOOD; HUMANS; INFANT, NEWBORN; LIPOPOLYSACCHARIDES; MONOCYTES; OBESITY; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROMOTER REGIONS, GENETIC; SEPSIS; TOLL-LIKE RECEPTOR 1; TOLL-LIKE RECEPTOR 2; TRANSCRIPTOME;

EID: 85031490383     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1700434     Document Type: Article

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