-
1
-
-
0035444539
-
Signal transduction by tumor necrosis factor and its relatives
-
DOI 10.1016/S0962-8924(01)02064-5, PII S0962892401020645
-
Baud V, Karin M (2001) Signal transduction by tumor necrosis factor and its relatives. Trends Cell Biol 11:372-377. (Pubitemid 32900529)
-
(2001)
Trends in Cell Biology
, vol.11
, Issue.9
, pp. 372-377
-
-
Baud, V.1
Karin, M.2
-
2
-
-
33746868630
-
-
ed Paul W (Lippincott Williams & Wilkins, Philadelphia)
-
Moldawer L (2003) Fundamental Immunology, ed Paul W (Lippincott Williams & Wilkins, Philadelphia), pp 749-773.
-
(2003)
Fundamental Immunology
, pp. 749-773
-
-
Moldawer, L.1
-
3
-
-
34249720998
-
Cytokines in the pathogenesis of rheumatoid arthritis
-
DOI 10.1038/nri2094, PII NRI2094
-
McInnes IB, Schett G (2007) Cytokines in the pathogenesis of rheumatoid arthritis. Nat Rev Immunol 7:429-442. (Pubitemid 46834849)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.6
, pp. 429-442
-
-
McInnes, I.B.1
Schett, G.2
-
4
-
-
33744785682
-
The effect of anti-TNF-alpha therapy on spinal bone mineral density in patients with Crohn's disease
-
DOI 10.1196/annals.1346.055
-
Pazianas M, Rhim AD, Weinberg AM, Su C, Lichtenstein GR (2006) The effect of anti-TNF-alpha therapy on spinal bone mineral density in patients with Crohn's disease. Ann N Y Acad Sci 1068:543-556. (Pubitemid 43832924)
-
(2006)
Annals of the New York Academy of Sciences
, vol.1068
, Issue.1
, pp. 543-556
-
-
Pazianas, M.1
Rhim, A.D.2
Weinberg, A.M.3
Su, C.4
Lichtenstein, G.R.5
-
5
-
-
34247127472
-
Macrophages and their products in rheumatoid arthritis
-
DOI 10.1097/BOR.0b013e32805e87ae, PII 0000228120070500000012
-
Szekanecz Z, Koch AE (2007) Macrophages and their products in rheumatoid arthritis. Curr Opin Rheumatol 19:289-295. (Pubitemid 46597469)
-
(2007)
Current Opinion in Rheumatology
, vol.19
, Issue.3
, pp. 289-295
-
-
Szekanecz, Z.1
Koch, A.E.2
-
6
-
-
0030858138
-
Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
-
DOI 10.1038/42030
-
Cella M, Engering A, Pinet V, Pieters J, Lanzavecchia A (1997) Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature 388:782-787. (Pubitemid 27375158)
-
(1997)
Nature
, vol.388
, Issue.6644
, pp. 782-787
-
-
Cella, M.1
Engering, A.2
Pinet, V.3
Pieters, J.4
Lanzavecchia, A.5
-
8
-
-
67650724069
-
Regulation and function of NF-kappaB transcription factors in the immune system
-
Vallabhapurapu S, Karin M (2009) Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol 27:693-733.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
9
-
-
0141483523
-
Transcriptional regulation by calcium, calcineurin, and NFAT
-
DOI 10.1101/gad.1102703
-
Hogan PG, Chen L, Nardone J, Rao A (2003) Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev 17:2205-2232. (Pubitemid 37128637)
-
(2003)
Genes and Development
, vol.17
, Issue.18
, pp. 2205-2232
-
-
Hogan, P.G.1
Chen, L.2
Nardone, J.3
Rao, A.4
-
10
-
-
0026643141
-
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation
-
Clipstone NA, Crabtree GR (1992) Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature 357:695-697.
-
(1992)
Nature
, vol.357
, pp. 695-697
-
-
Clipstone, N.A.1
Crabtree, G.R.2
-
11
-
-
52949087160
-
A signal-switch hypothesis for cross-regulation of cytokine and TLR signalling pathways
-
Ivashkiv LB (2008) A signal-switch hypothesis for cross-regulation of cytokine and TLR signalling pathways. Nat Rev Immunol 8:816-822.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 816-822
-
-
Ivashkiv, L.B.1
-
12
-
-
33947583822
-
Osteoimmunology: Shared mechanisms and crosstalk between the immune and bone systems
-
Takayanagi H (2007) Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat Rev Immunol 7:292-304.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 292-304
-
-
Takayanagi, H.1
-
13
-
-
0032485391
-
Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA
-
Chen L, Glover JN, Hogan PG, Rao A, Harrison SC (1998) Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA. Nature 392:42-48.
-
(1998)
Nature
, vol.392
, pp. 42-48
-
-
Chen, L.1
Glover, J.N.2
Hogan, P.G.3
Rao, A.4
Harrison, S.C.5
-
14
-
-
33847418504
-
Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells
-
Goodridge HS, Simmons RM, Underhill DM (2007) Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells. J Immunol 178:3107-3115. (Pubitemid 46333192)
-
(2007)
Journal of Immunology
, vol.178
, Issue.5
, pp. 3107-3115
-
-
Goodridge, H.S.1
Simmons, R.M.2
Underhill, D.M.3
-
15
-
-
77952311527
-
Calcineurin regulates innate antifungal immunity in neutrophils
-
Greenblatt MB, Aliprantis A, Hu B, Glimcher LH (2010) Calcineurin regulates innate antifungal immunity in neutrophils. J Exp Med 207:923-931.
-
(2010)
J Exp Med
, vol.207
, pp. 923-931
-
-
Greenblatt, M.B.1
Aliprantis, A.2
Hu, B.3
Glimcher, L.H.4
-
16
-
-
67650500800
-
CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation
-
Zanoni I, et al. (2009) CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation. Nature 460:264-268.
-
(2009)
Nature
, vol.460
, pp. 264-268
-
-
Zanoni, I.1
-
17
-
-
18744366041
-
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
-
DOI 10.1016/S1534-5807(02)00369-6
-
Takayanagi H, et al. (2002) Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev Cell 3:889-901. (Pubitemid 35460788)
-
(2002)
Developmental Cell
, vol.3
, Issue.6
, pp. 889-901
-
-
Takayanagi, H.1
Kim, S.2
Koga, T.3
Nishina, H.4
Isshiki, M.5
Yoshida, H.6
Saiura, A.7
Isobe, M.8
Yokochi, T.9
Inoue, J.-I.10
Wagner, E.F.11
Mak, T.W.12
Kodama, T.13
Taniguchi, T.14
-
18
-
-
11144354330
-
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis
-
DOI 10.1038/nature02444
-
Koga T, et al. (2004) Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis. Nature 428:758-763. (Pubitemid 38508286)
-
(2004)
Nature
, vol.428
, Issue.6984
, pp. 758-763
-
-
Koga, T.1
Inui, M.2
Inoue, K.3
Kim, S.4
Suematsu, A.5
Kobayashi, E.6
Iwata, T.7
Ohnishi, H.8
Matozaki, T.9
Kodama, T.10
Taniguchi, T.11
Takayanagi, H.12
Takai, T.13
-
19
-
-
11144355389
-
The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase
-
DOI 10.1073/pnas.0401602101
-
Mócsai A, et al. (2004) The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase. Proc Natl Acad Sci USA 101:6158-6163. (Pubitemid 38520544)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.16
, pp. 6158-6163
-
-
Mocsai, A.1
Humphrey, M.B.2
Van, Z.J.A.G.3
Hu, Y.4
Burghardt, A.5
Spusta, S.C.6
Majumdar, S.7
Lanier, L.L.8
Lowell, C.A.9
Nakamura, M.C.10
-
20
-
-
18444365894
-
Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis
-
DOI 10.1016/S1074-7613(02)00329-1
-
Chuvpilo S, et al. (2002) Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis. Immunity 16:881-895. (Pubitemid 34786486)
-
(2002)
Immunity
, vol.16
, Issue.6
, pp. 881-895
-
-
Chuvpilo, S.1
Jankevics, E.2
Tyrsin, D.3
Akimzhanov, A.4
Moroz, D.5
Jha, M.K.6
Schulze-Luehrmann, J.7
Santner-Nanan, B.8
Feoktistova, E.9
Konig, T.10
Avots, A.11
Schmitt, E.12
Berberich-Siebelt, F.13
Schimpl, A.14
Serfling, E.15
-
21
-
-
27744432009
-
Autoamplification of NFATc1 expression determines its essential role in bone homeostasis
-
DOI 10.1084/jem.20051150
-
Asagiri M, et al. (2005) Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J Exp Med 202:1261-1269. (Pubitemid 41586956)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.9
, pp. 1261-1269
-
-
Asagiri, M.1
Sato, K.2
Usami, T.3
Ochi, S.4
Nishina, H.5
Yoshida, H.6
Morita, I.7
Wagner, E.F.8
Mak, T.W.9
Serfling, E.10
Takayanagi, H.11
-
22
-
-
70349705616
-
NF-kappaB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism
-
Yao Z, Xing L, Boyce BF (2009) NF-kappaB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism. J Clin Invest 119:3024-3034.
-
(2009)
J Clin Invest
, vol.119
, pp. 3024-3034
-
-
Yao, Z.1
Xing, L.2
Boyce, B.F.3
-
23
-
-
40949123747
-
TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes
-
DOI 10.1038/ni1576, PII NI1576
-
Yarilina A, Park-Min KH, Antoniv T, Hu X, Ivashkiv LB (2008) TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes. Nat Immunol 9:378-387. (Pubitemid 351405107)
-
(2008)
Nature Immunology
, vol.9
, Issue.4
, pp. 378-387
-
-
Yarilina, A.1
Park-Min, K.-H.2
Antoniv, T.3
Hu, X.4
Ivashkiv, L.B.5
-
24
-
-
60749124122
-
The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules
-
Hao S, Baltimore D (2009) The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules. Nat Immunol 10:281-288.
-
(2009)
Nat Immunol
, vol.10
, pp. 281-288
-
-
Hao, S.1
Baltimore, D.2
-
25
-
-
70349308513
-
Molecular mediators of macrophage fusion
-
Helming L, Gordon S (2009) Molecular mediators of macrophage fusion. Trends Cell Biol 19:514-522.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 514-522
-
-
Helming, L.1
Gordon, S.2
-
26
-
-
9144275033
-
Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers
-
DOI 10.1038/sj.emboj.7600391
-
Bonizzi G, et al. (2004) Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers. EMBO J 23:4202-4210. (Pubitemid 39546158)
-
(2004)
EMBO Journal
, vol.23
, Issue.21
, pp. 4202-4210
-
-
Bonizzi, G.1
Bebien, M.2
Otero, D.C.3
Johnson-Vroom, K.E.4
Cao, Y.5
Vu, D.6
Jegga, A.G.7
Aronow, B.J.8
Ghosh, G.9
Rickert, R.C.10
Karin, M.11
-
27
-
-
0037413709
-
RelB is required for Peyer's patch development: Differential regulation of p52-RelB by lymphotoxin and TNF
-
DOI 10.1093/emboj/cdg004
-
Yilmaz ZB, Weih DS, Sivakumar V, Weih F (2003) RelB is required for Peyer's patch development: Differential regulation of p52-RelB by lymphotoxin and TNF. EMBO J 22:121-130. (Pubitemid 36091275)
-
(2003)
EMBO Journal
, vol.22
, Issue.1
, pp. 121-130
-
-
Yilmaz, Z.B.1
Weih, D.S.2
Sivakumar, V.3
Weih, F.4
-
28
-
-
41649089360
-
RelB is the NF-kappaB subunit downstream of NIK responsible for osteoclast differentiation
-
DOI 10.1073/pnas.0708576105
-
Vaira S, et al. (2008) RelB is the NF-kappaB subunit downstream of NIK responsible for osteoclast differentiation. Proc Natl Acad Sci USA 105:3897-3902. (Pubitemid 351723496)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.10
, pp. 3897-3902
-
-
Vaira, S.1
Johnson, T.2
Hirbe, A.C.3
Alhawagri, M.4
Anwisye, I.5
Sammut, B.6
O'Neal, J.7
Zou, W.8
Weilbaecher, K.N.9
Faccio, R.10
Novack, D.V.11
-
29
-
-
77953482256
-
Processing of the NF-kappa B2 precursor p100 to p52 is critical for RANKL-induced osteoclast differentiation
-
Maruyama T, et al. (2010) Processing of the NF-kappa B2 precursor p100 to p52 is critical for RANKL-induced osteoclast differentiation. J Bone Miner Res 25:1058-1067.
-
(2010)
J Bone Miner Res
, vol.25
, pp. 1058-1067
-
-
Maruyama, T.1
-
30
-
-
34547124586
-
NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1
-
DOI 10.1074/jbc.M610701200
-
Yamashita T, et al. (2007) NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1. J Biol Chem 282:18245-18253. (Pubitemid 47100255)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.25
, pp. 18245-18253
-
-
Yamashita, T.1
Yao, Z.2
Li, F.3
Zhang, Q.4
Badell, I.R.5
Schwarz, E.M.6
Takeshita, S.7
Wagner, E.F.8
Noda, M.9
Matsuo, K.10
Xing, L.11
Boyce, B.F.12
-
31
-
-
0030888186
-
2+ response amplitude and duration
-
Dolmetsch RE, Lewis RS, Goodnow CC, Healy JI (1997) Differential activation of transcription factors induced by Ca2+ response amplitude and duration. Nature 386:855-858. (Pubitemid 27181262)
-
(1997)
Nature
, vol.386
, Issue.6627
, pp. 855-858
-
-
Dolmetsch, R.E.1
Lewis, R.S.2
Goodnow, C.C.3
Healy, J.I.4
-
32
-
-
32244431975
-
The calcineurin phosphatase complex modulates immunogenic B cell responses
-
DOI 10.1016/j.immuni.2005.12.013, PII S1074761306000057
-
Winslow MM, Gallo EM, Neilson JR, Crabtree GR (2006) The calcineurin phosphatase complex modulates immunogenic B cell responses. Immunity 24:141-152. (Pubitemid 43214584)
-
(2006)
Immunity
, vol.24
, Issue.2
, pp. 141-152
-
-
Winslow, M.M.1
Gallo, E.M.2
Neilson, J.R.3
Crabtree, G.R.4
-
33
-
-
0032849010
-
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A
-
DOI 10.1126/science.285.5436.2129
-
Aramburu J, et al. (1999) Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A. Science 285:2129-2133. (Pubitemid 29451431)
-
(1999)
Science
, vol.285
, Issue.5436
, pp. 2129-2133
-
-
Aramburu, J.1
Yaffe, M.B.2
Lopez-Rodriguez, C.3
Cantley, L.C.4
Hogan, P.G.5
Rao, A.6
-
34
-
-
33646068740
-
NFATc1 regulation of the human beta3 integrin promoter in osteoclast differentiation
-
Crotti TN, et al. (2006) NFATc1 regulation of the human beta3 integrin promoter in osteoclast differentiation. Gene 372:92-102.
-
(2006)
Gene
, vol.372
, pp. 92-102
-
-
Crotti, T.N.1
-
35
-
-
55849088412
-
NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism
-
Aliprantis AO, et al. (2008) NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. J Clin Invest 118:3775-3789.
-
(2008)
J Clin Invest
, vol.118
, pp. 3775-3789
-
-
Aliprantis, A.O.1
-
36
-
-
33750597150
-
PLCgamma2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2
-
DOI 10.1172/JCI28775
-
Mao D, Epple H, Uthgenannt B, Novack DV, Faccio R (2006) PLCgamma2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2. J Clin Invest 116:2869-2879. (Pubitemid 44684472)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.11
, pp. 2869-2879
-
-
Mao, D.1
Epple, H.2
Uthgenannt, B.3
Novack, D.V.4
Faccio, R.5
-
37
-
-
33947240223
-
Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption
-
DOI 10.1083/jcb.200611083
-
Zou W, et al. (2007) Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption. J Cell Biol 176:877-888. (Pubitemid 46425547)
-
(2007)
Journal of Cell Biology
, vol.176
, Issue.6
, pp. 877-888
-
-
Zou, W.1
Kitaura, H.2
Reeve, J.3
Long, F.4
Tybulewicz, V.L.J.5
Shattil, S.J.6
Ginsberg, M.H.7
Ross, F.P.8
Teitelbaum, S.L.9
-
38
-
-
77949445679
-
TNF in host resistance to tuberculosis infection
-
Quesniaux VF, et al. (2010) TNF in host resistance to tuberculosis infection. Curr Dir Autoimmun 11:157-179.
-
(2010)
Curr Dir Autoimmun
, vol.11
, pp. 157-179
-
-
Quesniaux, V.F.1
-
39
-
-
0037471855
-
Sarcoidosis
-
DOI 10.1016/S0140-6736(03)12888-7
-
Baughman RP, Lower EE, du Bois RM (2003) Sarcoidosis. Lancet 361:1111-1118. (Pubitemid 36369566)
-
(2003)
Lancet
, vol.361
, Issue.9363
, pp. 1111-1118
-
-
Baughman, R.P.1
Lower, E.E.2
Du, B.R.M.3
|