Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide- induced inflammatory response in human monocytes

Nature Communications

Volumn 5, Issue , 2014, Pages

  Iiott, Nicholas E ^a   Heward, James A ^b   Roux, Benoit ^b   Tsitsiou, Eleni ^c   Fenwick, Peter S ^d   Lenzi, Luca ^e   Goodhead, Ian ^e   Hertz Fowler, Christiane ^e   Heger, Andreas ^a   Hall, Neil ^e   Donnelly, Louise E ^d   Sims, David ^a   Lindsay, Mark A ^b,c,d  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b University of Bath   (United Kingdom)

^c MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^d NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^e UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 8; LOCKED NUCLEIC ACID; LONG UNTRANSLATED RNA; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; LIPOPOLYSACCHARIDE; RNA;

IMMUNE RESPONSE; POLYSACCHARIDE; RNA;

ANALYSIS OF VARIANCE; ARTICLE; BINDING SITE; CELL FRACTIONATION; CELLULAR DISTRIBUTION; CHROMATIN; CONTROLLED STUDY; DNA BINDING; DNA STRAND; ENHANCER REGION; GENE EXPRESSION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; IC 50; IMMUNE RESPONSE; IMMUNOREGULATION; INFLAMMATION; INNATE IMMUNITY; LYMPHOBLASTOID CELL LINE; MONOCYTE; NONHUMAN; PROMOTER REGION; RANK SUM TEST; REGULATORY MECHANISM; RNA SEQUENCE; TRANSCRIPTION INITIATION SITE; CHEMICALLY INDUCED; DRUG EFFECTS; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

BINDING SITES; ENHANCER ELEMENTS, GENETIC; HUMANS; IMMUNITY, INNATE; INFLAMMATION; LIPOPOLYSACCHARIDES; MONOCYTES; NF-KAPPA B; PROMOTER REGIONS, GENETIC; RNA; RNA, LONG NONCODING; TRANSCRIPTION, GENETIC; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; PROTEIN BINDING;

EID: 84902286789     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4979     Document Type: Article

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