Adenomatous Polyposis Coli Defines Treg Differentiation and Anti-inflammatory Function through Microtubule-Mediated NFAT Localization

Cell Reports

Volumn 21, Issue 1, 2017, Pages 181-194

  Agüera González, Sonia ^a,b,c,e   Burton, Oliver T ^d,h   Vázquez Chávez, Elena ^a,b,c   Cuche, Céline ^a,b,c   Herit, Floriane ^a,b,c,f   Bouchet, Jérôme ^a,b,c   Lasserre, Rémi ^a,b,c,g   del Río Iñiguez, Iratxe ^a,b,c   Di Bartolo, Vincenzo ^a,b,c   Alcover, Andrés ^a,b,c  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

^c INSERM   (France)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e INSTITUT CURIE   (France)

^f INSTITUT COCHIN   (France)

^g AIX MARSEILLE UNIVERSITY   (France)

^h UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

adenomatous polyposis coli; cell polarity; colorectal cancer; IL 10; immunological synapse; intestinal tumors; microtubules; NFAT; T cell activation; Treg

Indexed keywords

APC PROTEIN; INTERLEUKIN 10; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR NFAT; APC PROTEIN, HUMAN; IL10 PROTEIN, HUMAN; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL NUCLEUS; COLON POLYPOSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMMUNOFLUORESCENCE; IMMUNOLOGICAL SYNAPSE; JURKAT E6.1 CELL LINE; LAMINA PROPRIA; LYMPHOCYTE DIFFERENTIATION; MESENTERY LYMPH NODE; MICROTUBULE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; GENETICS; HCT 116 CELL LINE; IMMUNOLOGY; JURKAT CELL LINE; LYMPH NODE; LYMPHOCYTE ACTIVATION; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE; TUMOR CELL LINE; ULTRASTRUCTURE;

ADENOMATOUS POLYPOSIS COLI; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; CELL DIFFERENTIATION; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HUMANS; INTERLEUKIN-10; JURKAT CELLS; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROTUBULES; NFATC TRANSCRIPTION FACTORS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY;

EID: 85030691783     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.09.020     Document Type: Article

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