Smad4 signalling in T cells is required for suppression of gastrointestinal cancer

Nature

Volumn 441, Issue 7096, 2006, Pages 1015-1019

  Kim, Byung Gyu ^a   Li, Cuiling ^b   Qiao, Wenhui ^b   Mamura, Mizuko ^a   Kasperczak, Barbara ^c   Anver, Miriam ^c   Wolfraim, Lawrence ^a   Hong, Suntaek ^a   Mushinski, Elizabeth ^a   Potter, Michael ^a   Kim, Seong Jin ^a   Fu, Xin Yuan ^d   Deng, Chuxia ^b   Letterio, John J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c SAIC FREDERICK INC   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL ENGINEERING; GASTROENTEROLOGY; GENES; GENETIC ENGINEERING; PATIENT TREATMENT; TUMORS;

GASTROINTESTINAL CANCER; INFLAMMATORY CELLS; POLYPOSIS; SUPPRESSOR GENE; T CELLS;

CELLS;

CYTOKINE; INTERLEUKIN 13; INTERLEUKIN 5; INTERLEUKIN 6; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

CANCER; COMMUNICATION; EVOLUTIONARY BIOLOGY; GENE EXPRESSION; GROWTH FORM; JUVENILE; MUTATION; RODENT; SIGNALING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL COMMUNICATION; COLON MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIGESTIVE SYSTEM CANCER; EPITHELIUM CELL; FEMALE; GENE DELETION; GENE MUTATION; GENETIC PREDISPOSITION; INFLAMMATORY INFILTRATE; JUVENILE POLYP; MALE; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SMAD4 GENE; STOMACH MUCOSA; STROMA CELL; T LYMPHOCYTE; TH2 CELL; TUMOR LOCALIZATION; TUMOR SUPPRESSOR GENE;

EID: 33745578957     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature04846     Document Type: Article

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