Zinc and the cytoskeleton in the neuronal modulation of transcription factor NFAT

Journal of Cellular Physiology

Volumn 210, Issue 1, 2007, Pages 246-256

  Mackenzie, Gerardo C ^a,b   Oteiza, Patricia I ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; CALCIUM; COLCHICINE; CYTOCHALASIN D; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; THIOCTIC ACID; TRANSCRIPTION FACTOR NFAT; TUBULIN; VINBLASTINE; ZINC;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL NUCLEUS; CELL SURVIVAL; CONTROLLED STUDY; CULTURE MEDIUM; CYTOSKELETON; CYTOSOL; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RAT; ZINC DEFICIENCY;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTIOXIDANTS; CALCINEURIN; CALCIUM; CELL NUCLEUS; CELL SURVIVAL; CEREBELLUM; CHELATING AGENTS; CYCLOSPORINE; CYTOSKELETON; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; NEURONS; NFATC TRANSCRIPTION FACTORS; OXIDANTS; PC12 CELLS; PROMOTER REGIONS (GENETICS); RATS; RATS, WISTAR; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANSFECTION; TUBULIN MODULATORS; ZINC;

EID: 33845491891     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20861     Document Type: Article

References (57)

1. Beals CR, Sheridan CM, Turck CW, Gardner P, Crabtree GR. 1997. Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3. Science 275:1930-1934.
2. Benedito AB, Lehtinen M, Massol R, Lopes UG, Kirchhausen T, Rao A, Bonni A. 2005. The transcription factor NFAT3 mediates neuronal survival. J Biol Chem 280:2818-2825.
3. Borodinsky LN, Fiszman ML. 1998. Extracellular potassium concentration regulates proliferation of immature cerebellar granule cells. Brain Res Dev Brain Res 107:43-48.
4. Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
5. Dawson TM, Steiner JP, Lyons WE, Fotuhi M, Blue M, Snyder SH. 1994. The immunophilins, FK506 binding protein and cyclophilin, are discretely localized in the brain: Relationship to calcineurin. Neuroscience 62:569-580.
6. Devadas S, Zaritskaya L, Rhee SG, Oberley L, Williams MS. 2002. Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation:selective regulation of mitogen-activated protein kinase activation and Fas ligand expression. J Exp Med 195:59-70.
7. Dignam JD, Lebovitz RM, Boeder RG. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489.
8. 2+ response amplitude and duration. Nature 386:855-858.
9. Durand DB, Shaw JP, Bush MR, Replogle RE, Belagaje R, Crabtree GR. 1988. Characterization of antigen receptor response elements within the interleukin-2 enhancer. Mol Cell Biol 8:1715-1724.
10. Dvergsten CL, Fosmire GJ, Ollerich DA, Sandstead HH. 1983. Alterations in the postnatal development of the cerebellar cortex due to zinc deficiency. I. Impaired acquisition of granule cells. Brain Res 271:217-226.
11. Dvergsten CL, Fosmire GJ, Ollerich DA, Sandstead HH. 1984a. Alterations in the postnatal development of the cerebellar cortex due to zinc deficiency. II. Impaired maturation of Purkinje cells. Brain Res 318:11-20.
12. Dvergsten CL, Johnson LA, Sandstead HH. 1984b. Alterations in the postnatal development of the cerebellar cortex due to zinc deficiency. III. Impaired dendritic differentiation of basket and stellate cells. Brain Res 318:21-26.
13. Erlejman AG, Oteiza PI. 2002. The oxidant defense system in human neuroblastoma IMR-32 cells predifferentiation and postdifferentiation to neuronal phenotypes. Neurochem Res 27:1499-1506.
14. Furuke K, Shiraishi M, Mostowski HS, Bloom ET. 1999. Fas ligand induction in human NK cells is regulated by redox through a calcineurin-nuclear factors of activated T cell-dependent pathway. J Immunol 162:1988-1993.
15. Gallo V, Kingsbury A, Balazs R, Jorgensen OS. 1987. The role of depolarization in the survival and differentiation of cerebellar granule cells in culture. J Neurosci 7:2203-2213.
16. Giannakakou P, Sackett DL, Ward Y, Webster KR, Blagosklonny MV, Fojo T. 2000. p53 is associated with cellular microtubules and is transported to the nucleus by dynein. Nat Cell Biol 2:709-717.
17. Goldfarb DS, Corbett AH, Mason DA, Harreman MT, Adam SA. 2004. Importin alpha: A multipurpose nuclear-transport receptor. Trends Cell Biol 14:505-514.
18. Graef IA, Mermelstein PG, Stankunas K, Neilson JR, Deisseroth K, Tsien RW, Crabtree GR. 1999. L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons. Nature 401:703-708.
19. Graef IA, Chen F, Chen L, Kuo A, Crabtree GR. 2001a. Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature. Cell 105:863-875.
20. Graef IA, Chen F, Crabtree GR. 2001b. NFAT signaling in vertebrate development. Curr Opin Genet Dev 11:505-512.
21. Graef IA, Gastier JM, Francke U, Crabtree GR. 2001c. Evolutionary relationships among Rel domains indicate functional diversification by recombination. Proc Natl Acad Sci USA 98:5740-5745.
22. Graef IA, Wang F, Charron F, Chen L, Neilson J, Tessier-Lavigne M, Crabtree GR. 2003. Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons. Cell 113:657-670.
23. Groth RD, Mermelstein PG. 2003. Brain-derived neurotrophic factor activation of NFAT (nuclear factor of activated T-cells)-dependent transcription: A role for the transcription factor NFATc4 in neurotrophin-mediated gene expression. J Neurosci 23:8125-8134.
24. Hanz S, Fainzilber M. 2004. Integration of retrograde axonal and nuclear transport mechanisms in neurons: Implications for therapeutics. Neuroscientist 10:404-408.
25. Hanz S, Perlson E, Willis D, Zheng JQ, Massarwa R, Huerta JJ, Koltzenburg M, Kohler M, van-Minnen J, Twiss JL, Fainzilber M. 2003. Axoplasmic importins enable retrograde injury signaling in lesioned nerve. Neuron 40:1095-1104.
26. Herin GA, Aizenman E. 2004. Amino terminal domain regulation of NMDA receptor function. Eur J Pharmacol 500:101-111.
27. Hesketh JE. 1981. Impaired microtubule assembly in brain from zinc-deficient pigs and rats. Int J Biochem 13:921-926.
28. Ho E, Ames BN. 2002. Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFkappa B, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line. Proc Natl Acad Sci USA 99:16770-16775.
29. Huang C, Mattjus P, Ma WY, Rincon M, Chen NY, Brown RE, Dong Z. 2000. Involvement of nuclear factor of activated T cells activation in UV response. Evidence from cell culture and transgenic mice. J Biol Chem 275:9143-9149.
30. Huang C, Ding M, Li J, Leonard SS, Rojanasakul Y, Castranova V, Vallyathan V, Ju G, Shi X. 2001a. Vanadium-induced nuclear factor of activated T cells activation through hydrogen peroxide. J Biol Chem 276:22397-22403.
31. Huang C, Li J, Costa M, Zhang Z, Leonard SS, Castranova V, Vallyathan V, Ju G, Shi X. 2001b. Hydrogen peroxide mediates activation of nuclear factor of activated T cells (NFAT) by nickel subsulfide. Cancer Res 61:8051-8057.
32. Jayanthi S, Deng X, Ladenheim B, McCoy MT, Cluster A, Cai NS, Cadet JL. 2005. Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis. Proc Natl Acad Sci USA 102:868-873.
33. Kraft R, Grimm C, Grosse K, Hoffmann A, Sauerbruch S, Kettenmann H, Schultz G, Harteneck C. 2004. Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia. Am J Physiol Cell Physiol 286:C129-137.
34. Kramer D, Fresu L, Ashby DS, Freeman TC, Genazzani AA. 2003. Calcineurin controls the expression of numerous genes in cerebellar granule cells. Mol Cell Neurosci 23:325-330.
35. Macian F, López-Rodriguez C, Rao A. 2001. Partners in transcription: NFAT and AP-1. Oncogene 20:2476-2489.
36. Mackenzie GG, Zago MP, Keen CL, Oteiza PI. 2002. Low intracellular zinc impairs the translocation of activated NF-kappa B to the nuclei in human neuroblastoma IMR-32 cells. J Biol Chem 277:34610-34617.
37. Mackenzie GG, Keen CL, Oteiza PI. 2006a. Microtubules are required for NF-κB nuclear translocation in neuroblastoma IMR-32 cells: Modulation by zinc. J Neurochem (in press).
38. Mackenzie GG, Zago MP, Erlejman AG, Aimo L, Keen CL, Oteiza PI. 2006b. alpha-Lipoic acid and N-acetyl cysteine prevent zinc deficiency-induced activation of NF-kappaB and AP-1 transcription factors in human neuroblastoma IMR-32 cells. Free Radic Res 40:75-84.
39. Mansuy IM, Mayford M, Jacob B, Kandel ER, Bach ME. 1998. Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory. Cell 92:39-49.
40. Meffert MK, Chang JM, Wiltgen BJ, Fanselow MS, Baltimore D. 2003. NF-kappaB functions in synaptic signaling and behavior. Nat Neurosci 6:1072-1078.
41. Muller JM, Rupec RA, Baeuerle PA. 1997. Study of gene regulation by NF-kappa B and AP-1 in response to reactive oxygen intermediates. Methods 11:301-312.
42. Neill D, Hughes D, Edwardson JA, Rima BK, Allsop D. 1994. Human IMR-32 neuroblastoma cells as a model cell line in Alzheimer's disease research. J Neurosci Res 39:482-493.
43. Osborn L, Kunkel S, Nabel GJ. 1989. Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B. Proc Natl Acad Sci USA 86:2336-2340.
44. Oteiza PI, Hurley LS, Lonnerdal B, Keen CL. 1988. Marginal zinc deficiency affects maternal brain microtubule assembly in rats. J Nutr 118:735-738.
45. Oteiza PI, Cuellar S, Lonnerdal B, Hurley LS, Keen CL. 1990a. Influence of maternal dietary zinc intake on in vitro tubulin polymerization in fetal rat brain. Teratology 41:97-104.
46. Oteiza PI, Hurley LS, Lonnerdal B, Keen CL. 1990b. Effects of marginal zinc deficiency on microtubule polymerization in the developing rat brain. Biol Trace Elem Res 24:13-23.
47. Oteiza PI, Clegg MS, Zago MP, Keen CL. 2000. Zinc deficiency induces oxidative stress and AP-1 activation in 3T3 cells. Free Radic Biol Med 28:1091-1099.
48. Rincon M, Flavell RA. 1997. Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells. Mol Cell Biol 17:1522-1534.
49. Schimmelpfeng J, Weibezahn KF, Dertinger H. 2004. Quantification of NGF-dependent neuronal differentiation of PC-12 cells by means of neurofilament-L mRNA expression and neuronal outgrowth. J Neurosci Methods 139:299-306.
50. Serfling E, Barthelmas R, Pfeuffer I, Schenk B, Zarius S, Swoboda R, Mercurio F, Karin M. 1989. Ubiquitous and lymphocyte-specific factors are involved in the induction of the mouse interleukin 2 gene in T lymphocytes. EMBO J 8:465-473.
51. Shaw JP, Utz PJ, Durand DB, Toole JJ, Emmel EA, Crabtree GR. 1988. Identification of a putative regulator of early T cell activation genes. Science 241:202-205.
52. Smith MA, Herson PS, Lee K, Pinnock RD, Ashford ML. 2003. Hydrogen-peroxide-induced toxicity of rat striatal neurones involves activation of a non-selective cation channel. J Physiol 547:417-425.
53. Steiner JP, Dawson TM, Fotuhi M, Glatt CE, Snowman AM, Cohen N, Snyder SH. 1992. High brain densities of the immunophilin FKBP colocalized with calcineurin. Nature 358:584-587.
54. 2+ signals and immunosuppression. Nature 383:837-840.
55. Verstraeten SV, Zago MP, MacKenzie GG, Keen CL, Oteiza PI. 2004. Influence of zinc deficiency on cell-membrane fluidity in Jurkat, 3T3 and IMR-32 cells. Biochem J 378:579-587.
56. Winder DG, Mansuy IM, Osman M, Moallem TM, Kandel ER. 1998. Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin. Cell 92:25-37.
57. Zago MP, Mackenzie GG, Adamo AM, Keen CL, Oteiza PI. 2005. Differential Modulation of MAP Kinases by Zinc Deficiency in IMR-32 Cells: Role of H(2)O(2). Antioxid Redox Signal 7:1773-1782.