Enzyme replacement in the CSF to treat metachromatic leukodystrophy in mouse model using single intracerebroventricular injection of self-complementary AAV1 vector

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Hironaka, Kohei ^a   Yamazaki, Yoshiyuki ^a   Hirai, Yukihiko ^a   Yamamoto, Motoko ^a   Miyake, Noriko ^a   Miyake, Koichi ^a   Okada, Takashi ^a   Morita, Akio ^a   Shimada, Takashi ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CEREBROSIDE SULFATASE;

ADENOVIRIDAE; ANIMAL; C57BL MOUSE; CEREBROSPINAL FLUID; ENZYME REPLACEMENT; ENZYMOLOGY; GENE THERAPY; GENE VECTOR; GENETICS; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; KNOCKOUT MOUSE; LEUKODYSTROPHY, METACHROMATIC; METABOLISM; MOUSE; PROCEDURES; SCID MOUSE; TREATMENT OUTCOME;

ADENOVIRIDAE; ANIMALS; CEREBROSIDE-SULFATASE; CEREBROSPINAL FLUID; ENZYME REPLACEMENT THERAPY; GENETIC THERAPY; GENETIC VECTORS; INJECTIONS, INTRAVENTRICULAR; LEUKODYSTROPHY, METACHROMATIC; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, SCID; TREATMENT OUTCOME;

EID: 84939523769     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep13104     Document Type: Article

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