Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that mpp6 stimulates RNA decay and recruits the Mtr4 helicase

eLife

Volumn 6, Issue , 2017, Pages

  Wasmuth, Elizabeth V ^a   Zinder, John C ^a   Zattas, Dimitrios ^a   Das, Mom ^a   Lima, Christopher D ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; FUNGAL RNA; MPP 6 PROTEIN; MTR 4 HELICASE; UNCLASSIFIED DRUG; DEAD BOX PROTEIN; DNA BINDING PROTEIN; EXOSOME MULTIENZYME RIBONUCLEASE COMPLEX; LRP1 PROTEIN, S CEREVISIAE; MPP6 PROTEIN, S CEREVISIAE; MTR4 PROTEIN, S CEREVISIAE; NUCLEAR PROTEIN; PROTEIN BINDING; RNA BINDING PROTEIN; RRP6 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; CONTROLLED STUDY; DEAE CELLULOSE CHROMATOGRAPHY; ENZYME ACTIVITY; ESCHERICHIA COLI; EXOSOME; FUNGUS GROWTH; GENE MUTATION; GENETIC ANALYSIS; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; RNA BINDING; RNA DEGRADATION; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION; CHEMISTRY; DNA MUTATIONAL ANALYSIS; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; RNA STABILITY;

CRYSTALLOGRAPHY, X-RAY; DEAD-BOX RNA HELICASES; DNA MUTATIONAL ANALYSIS; DNA-BINDING PROTEINS; EXOSOME MULTIENZYME RIBONUCLEASE COMPLEX; EXOSOMES; MODELS, MOLECULAR; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; RNA STABILITY; RNA, FUNGAL; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 85029224657     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.29062     Document Type: Article

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