Insight into the RNA exosome complex through modeling pontocerebellar hypoplasia type 1b disease mutations in yeast

Genetics

Volumn 205, Issue 1, 2017, Pages 221-237

  Fasken, Milo B ^a   Losh, Jillian S ^c,d   Leung, Sara W ^a   Brutus, Sergine ^a   Avin, Brittany ^a   Vaught, Jillian C ^c   Potter Birriel, Jennifer ^a   Craig, Taylor ^a   Conn, Graeme L ^b   Mills Lujan, Katherine ^a   Corbett, Anita H ^a   van Hoof, Ambro ^c,d  

^a EMORY UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF TEXAS   (United States)

Author keywords

EXOSC2; EXOSC3; Pontocerebellar hypoplasia type 1b; RNA exosome; RNA processing degradation; Rrp40

Indexed keywords

AMINO ACID; EXORIBONUCLEASE; MESSENGER RNA; MYC PROTEIN; PROTEASOME; RNA; RRP40 PROTEIN; SMALL NUCLEAR RNA; UNCLASSIFIED DRUG; EXOSOME MULTIENZYME RIBONUCLEASE COMPLEX; RNA BINDING PROTEIN; RRP40 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CARBOXY TERMINAL SEQUENCE; CELL GROWTH; CEREBELLUM HYPOPLASIA; CONTROLLED STUDY; EXOSOME; GENE MUTATION; NERVE CELL; NONHUMAN; PONTOCEREBELLAR HYPOPLASIA TYPE 1B; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; WILD TYPE; CEREBELLUM DISEASE; GENETICS; METABOLISM; MUTATION; RNA STABILITY;

CEREBELLAR DISEASES; EXORIBONUCLEASES; EXOSOME MULTIENZYME RIBONUCLEASE COMPLEX; MUTATION; RNA STABILITY; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 85008474084     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.116.195917     Document Type: Article

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