Cryptic Pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase

Cell

Volumn 121, Issue 5, 2005, Pages 725-737

  Wyers, Françoise ^b   Rougemaille, Mathieu ^b   Badis, Gwenaël ^a   Rousselle, Jean Claude ^a   Dufour, Marie Elisabeth ^b   Boulay, Jocelyne ^b   Régnault, Béatrice ^a   Devaux, Frédéric ^c   Namane, Abdelkader ^a   Séraphin, Bertrand ^a,b   Libri, Domenico ^b   Jacquier, Alain ^a  

^a INSTITUT PASTEUR   (France)

^b CENTRE DE GÉNÉTIQUE MOLÉCULAIRE   (France)

^c ECOLE NORMALE SUPÉRIEURE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3',5' EXONUCLEASE; DNA DIRECTED RNA POLYMERASE; DNA DIRECTED RNA POLYMERASE III; EXONUCLEASE; POLYADENYLIC ACID POLYMERASE TRF4P; POLYNUCLEOTIDE ADENYLYLTRANSFERASE; RNA BINDING PROTEIN; RNA POLYMERASE II; SPACER DNA; UNCLASSIFIED DRUG; ZINC KNUCKLE PROTEIN AIR1P; ZINC KNUCKLE PROTEIN AIR2P;

ARTICLE; CELL NUCLEUS; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME MECHANISM; GENE EXPRESSION; GENE SILENCING; GENOME; INFORMATION; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; QUALITY CONTROL; RNA TRANSCRIPTION; SACCHAROMYCES CEREVISIAE;

EID: 20444368036     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2005.04.030     Document Type: Article

References (40)

1. C. Allmang, J. Kufel, G. Chanfreau, P. Mitchell, E. Petfalski, and D. Tollervey Functions of the exosome in rRNA, snoRNA and snRNA synthesis EMBO J. 18 1999 5399 5410
2. C. Allmang, E. Petfalski, A. Podtelejnikov, M. Mann, D. Tollervey, and P. Mitchell The yeast exosome and human PM-Scl are related complexes of 3′→5′ exonucleases Genes Dev. 13 1999 2148 2158
3. P. Aloy, F.D. Ciccarelli, C. Leutwein, A.C. Gavin, G. Superti-Furga, P. Bork, B. Bottcher, and R.B. Russell A complex prediction: three-dimensional model of the yeast exosome EMBO Rep. 3 2002 628 635
4. C. Bousquet-Antonelli, C. Presutti, and D. Tollervey Identification of a regulated pathway for nuclear pre-mRNA turnover Cell 102 2000 765 775
5. I.B. Castano, S. Heath-Pagliuso, B.U. Sadoff, D.J. Fitzhugh, and M.F. Christman A novel family of TRF (DNA topoisomerase I-related function) genes required for proper nuclear segregation Nucleic Acids Res. 24 1996 2404 2410
6. B. Das, J.S. Butler, and F. Sherman Degradation of normal mRNA in the nucleus of Saccharomyces cerevisiae Mol. Cell. Biol. 23 2003 5502 5515
7. J. de la Cruz, D. Kressler, D. Tollervey, and P. Linder Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3′ end formation of 5.8S rRNA in Saccharomyces cerevisiae EMBO J. 17 1998 1128 1140
8. M. Dreyfus, and P. Regnier The poly(A) tail of mRNAs: bodyguard in eukaryotes, scavenger in bacteria Cell 111 2002 611 613
9. E. Egyhazi Quantitation of turnover and export to the cytoplasm of hnRNA transcribed in the Balbiani rings Cell 7 1976 507 515
10. J. Fleischmann, H. Liu, and C.P. Wu Polyadenylation of ribosomal RNA by Candida albicans also involves the small subunit BMC Mol. Biol. 5 2004 17
11. E. Gari, L. Piedrafita, M. Aldea, and E. Herrero A set of vectors with a tetracycline-regulatable promoter system for modulated gene expression in Saccharomyces cerevisiae Yeast 13 1997 837 848
12. Y. Ho, A. Gruhler, A. Heilbut, G.D. Bader, L. Moore, S.L. Adams, A. Millar, P. Taylor, K. Bennett, and K. Boutilier Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry Nature 415 2002 180 183
13. W.K. Huh, J.V. Falvo, L.C. Gerke, A.S. Carroll, R.W. Howson, J.S. Weissman, and E.K. O'Shea Global analysis of protein localization in budding yeast Nature 425 2003 686 691
14. K. Inoue, T. Mizuno, K. Wada, and M. Hagiwara Novel RING finger proteins, Air1p and Air2p, interact with Hmt1p and inhibit the arginine methylation of Npl3p J. Biol. Chem. 275 2000 32793 32799
15. T. Ito, T. Chiba, R. Ozawa, M. Yoshida, M. Hattori, and Y. Sakaki A comprehensive two-hybrid analysis to explore the yeast protein interactome Proc. Natl. Acad. Sci. USA 98 2001 4569 4574
16. A.W. Johnson Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively Mol. Cell. Biol. 17 1997 6122 6130
17. J.M. Johnson, S. Edwards, D. Shoemaker, and E.E. Schadt Dark matter in the genome: evidence of widespread transcription detected by microarray tiling experiments Trends Genet. 21 2005 93 102
18. S. Kadaba, A. Krueger, T. Trice, A.M. Krecic, A.G. Hinnebusch, and J. Anderson Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae Genes Dev. 18 2004 1227 1240
19. W. Keller, and L. Minvielle-Sebastia A comparison of mammalian and yeast pre-mRNA 3′-end processing Curr. Opin. Cell Biol. 9 1997 329 336
20. M. Kim, N.J. Krogan, L. Vasiljeva, O.J. Rando, E. Nedea, J.F. Greenblatt, and S. Buratowski The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II Nature 432 2004 517 522
21. N.J. Krogan, W.T. Peng, G. Cagney, M.D. Robinson, R. Haw, G. Zhong, X. Guo, X. Zhang, V. Canadien, and D.P. Richards High-definition macromolecular composition of yeast RNA-processing complexes Mol. Cell 13 2004 225 239
22. L. Kuai, F. Fang, J.S. Butler, and F. Sherman Polyadenylation of rRNA in Saccharomyces cerevisiae Proc. Natl. Acad. Sci. USA 101 2004 8581 8586
23. J.E. Kwak, L. Wang, S. Ballantyne, J. Kimble, and M. Wickens Mammalian GLD-2 homologs are poly(A) polymerases Proc. Natl. Acad. Sci. USA 101 2004 713 724
24. J. LaCava, J. Houseley, C. Saveanu, E. Petfalski, E. Thompson, A. Jacquier, and D. Tollervey RNA degradation by the exosome is promoted by a nuclear polyadenylation complex this issue Cell 121 2005
25. S. Liang, M. Hitomi, Y.H. Hu, Y. Liu, and A.M. Tartakoff A DEAD-box-family protein is required for nucleocytoplasmic transport of yeast mRNA Mol. Cell. Biol. 16 1996 5139 5146
26. D. Libri, K. Dower, J. Boulay, R. Thomsen, M. Rosbash, and T.H. Jensen Interactions between mRNA export commitment, 3′-end quality control, and nuclear degradation Mol. Cell. Biol. 22 2002 8254 8266
27. P. Mitchell, and D. Tollervey Musing on the structural organization of the exosome complex Nat. Struct. Biol. 7 2000 843 846
28. M. Nonet, C. Scafe, J. Sexton, and R. Young Eucaryotic RNA polymerase conditional mutant that rapidly ceases mRNA synthesis Mol. Cell. Biol. 7 1987 1602 1611
29. E. Petfalski, T. Dandekar, Y. Henry, and D. Tollervey Processing of the precursors to small nucleolar RNAs and rRNAs requires common components Mol. Cell. Biol. 18 1998 1181 1189
30. N. Proudfoot, and J. O'Sullivan Polyadenylation: a tail of two complexes Curr. Biol. 12 2002 R855 R857
31. G. Rigaut, A. Shevchenko, B. Rutz, M. Wilm, M. Mann, and B. Seraphin A generic protein purification method for protein complex characterization and proteome exploration Nat. Biotechnol. 17 1999 1030 1032
32. T. Ruusala, D. Andersson, M. Ehrenberg, and C.G. Kurland Hyper-accurate ribosomes inhibit growth EMBO J. 3 1984 2575 2580
33. S.C. Schroeder, B. Schwer, S. Shuman, and D. Bentley Dynamic association of capping enzymes with transcribing RNA polymerase II Genes Dev. 14 2000 2435 2440
34. H. Schurer, S. Schiffer, A. Marchfelder, and M. Morl This is the end: processing, editing and repair at the tRNA 3′-terminus Biol. Chem. 382 2001 1147 1156
35. M.F. Symmons, M.G. Williams, B.F. Luisi, G.H. Jones, and A.J. Carpousis Running rings around RNA: a superfamily of phosphate-dependent RNases Trends Biochem. Sci. 27 2002 11 18
36. C. Torchet, C. Bousquet-Antonelli, L. Milligan, E. Thompson, J. Kufel, and D. Tollervey Processing of 3′-extended read-through transcripts by the exosome can generate functional mRNAs Mol. Cell 9 2002 1285 1296
37. A. van Hoof, P. Lennertz, and R. Parker Yeast exosome mutants accumulate 3′-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs Mol. Cell. Biol. 20 2000 441 452
38. V.E. Velculescu, L. Zhang, W. Zhou, J. Vogelstein, M.A. Basrai, D.E. Bassett Jr., P. Hieter, B. Vogelstein, and K.W. Kinzler Characterization of the yeast transcriptome Cell 88 1997 243 251
39. Z. Wang, I.B. Castano, A. De Las Penas, C. Adams, and M.F. Christman Pol kappa: A DNA polymerase required for sister chromatid cohesion Science 289 2000 774 779
40. S. West, N. Gromak, and N.J. Proudfoot Human 5′→3′ exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites Nature 432 2004 522 525