Rrp6p Controls mRNA Poly(A) Tail Length and Its Decoration with Poly(A) Binding Proteins

Molecular Cell

Volumn 47, Issue 2, 2012, Pages 267-280

  Schmid, Manfred ^a   Poulsen, Mathias Bach ^a,b   Olszewski, Pawel ^a   Pelechano, Vicent ^c   Saguez, Cyril ^a,d   Gupta, Ishaan ^c   Steinmetz, Lars M ^c   Moore, Claire ^b   Jensen, Torben Heick ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; MESSENGER RIBONUCLEOPROTEIN; MESSENGER RNA; MESSENGER RNA PRECURSOR; NAB2P PROTEIN; NUCLEAR PROTEIN; POLYADENYLATED RNA; POLYADENYLIC ACID BINDING PROTEIN; RIBONUCLEOPROTEIN; RNA POLYMERASE; RRP6P PROTEIN; TRF4P PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EXOSOME; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; POLYADENYLATION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTEIN TARGETING; REGULATORY MECHANISM; RNA STABILITY; RNA TRANSLATION; SIGNAL TRANSDUCTION;

BASE SEQUENCE; CELL NUCLEUS; CYTOPLASM; DNA-DIRECTED DNA POLYMERASE; EXORIBONUCLEASES; EXOSOMES; GENE EXPRESSION REGULATION, FUNGAL; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLY A; POLY(A)-BINDING PROTEINS; PROTEIN BINDING; RNA; RNA, MESSENGER; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84864322244     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2012.05.005     Document Type: Article

References (38)

1. Amrani N., Minet M., Le Gouar M., Lacroute F., Wyers F. Yeast Pab1 interacts with Rna15 and participates in the control of the poly(A) tail length in vitro. Mol. Cell. Biol. 1997, 17:3694-3701.
2. Assenholt J., Mouaikel J., Andersen K.R., Brodersen D.E., Libri D., Jensen T.H. Exonucleolysis is required for nuclear mRNA quality control in yeast THO mutants. RNA 2008, 14:2305-2313.
3. Boeck R., Lapeyre B., Brown C.E., Sachs A.B. Capped mRNA degradation intermediates accumulate in the yeast spb8-2 mutant. Mol. Cell. Biol. 1998, 18:5062-5072.
4. Bonnerot C., Boeck R., Lapeyre B. The two proteins Pat1p (Mrt1p) and Spb8p interact in vivo, are required for mRNA decay, and are functionally linked to Pab1p. Mol. Cell. Biol. 2000, 20:5939-5946.
5. Bousquet-Antonelli C., Presutti C., Tollervey D. Identification of a regulated pathway for nuclear pre-mRNA turnover. Cell 2000, 102:765-775.
6. Brown C.E., Sachs A.B. Poly(A) tail length control in Saccharomyces cerevisiae occurs by message-specific deadenylation. Mol. Cell. Biol. 1998, 18:6548-6559.
7. Brune C., Munchel S.E., Fischer N., Podtelejnikov A.V., Weis K. Yeast poly(A)-binding protein Pab1 shuttles between the nucleus and the cytoplasm and functions in mRNA export. RNA 2005, 11:517-531.
8. Callahan K.P., Butler J.S. TRAMP complex enhances RNA degradation by the nuclear exosome component Rrp6. J. Biol. Chem. 2010, 285:3540-3547.
9. Dheur S., Nykamp K.R., Viphakone N., Swanson M.S., Minvielle-Sebastia L. Yeast mRNA Poly(A) tail length control can be reconstituted in vitro in the absence of Pab1p-dependent Poly(A) nuclease activity. J. Biol. Chem. 2005, 280:24532-24538.
10. Eckmann C.R., Rammelt C., Wahle E. Control of poly(A) tail length. Wiley Interdiscip. Rev. RNA 2011, 2:348-361.
11. Fasken M.B., Stewart M., Corbett A.H. Functional significance of the interaction between the mRNA-binding protein, Nab2, and the nuclear pore-associated protein, Mlp1, in mRNA export. J. Biol. Chem. 2008, 283:27130-27143.
12. Galy V., Gadal O., Fromont-Racine M., Romano A., Jacquier A., Nehrbass U. Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1. Cell 2004, 116:63-73.
13. Hector R.E., Nykamp K.R., Dheur S., Anderson J.T., Non P.J., Urbinati C.R., Wilson S.M., Minvielle-Sebastia L., Swanson M.S. Dual requirement for yeast hnRNP Nab2p in mRNA poly(A) tail length control and nuclear export. EMBO J. 2002, 21:1800-1810.
14. Houseley J., Tollervey D. The many pathways of RNA degradation. Cell 2009, 136:763-776.
15. Iglesias N., Tutucci E., Gwizdek C., Vinciguerra P., Von Dach E., Corbett A.H., Dargemont C., Stutz F. Ubiquitin-mediated mRNP dynamics and surveillance prior to budding yeast mRNA export. Genes Dev. 2010, 24:1927-1938.
16. Jensen T.H., Moore C. Reviving the exosome. Cell 2005, 121:660-662.
17. Kadaba S., Krueger A., Trice T., Krecic A.M., Hinnebusch A.G., Anderson J. Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae. Genes Dev. 2004, 18:1227-1240.
18. LaCava J., Houseley J., Saveanu C., Petfalski E., Thompson E., Jacquier A., Tollervey D. RNA degradation by the exosome is promoted by a nuclear polyadenylation complex. Cell 2005, 121:713-724.
19. Lemay J.F., D'Amours A., Lemieux C., Lackner D.H., St-Sauveur V.G., Bahler J., Bachand F. The nuclear poly(A)-binding protein interacts with the exosome to promote synthesis of noncoding small nucleolar RNAs. Mol. Cell 2010, 37:34-45.
20. Lemay J.F., Lemieux C., St-Andre O., Bachand F. Crossing the borders: poly(A)-binding proteins working on both sides of the fence. RNA Biol. 2010, 7:291-295.
21. Lemieux C., Marguerat S., Lafontaine J., Barbezier N., Bahler J., Bachand F. A pre-mRNA degradation pathway that selectively targets intron-containing genes requires the nuclear poly(A)-binding protein. Mol. Cell 2011, 44:108-119.
22. Libri D. Nuclear poly(a)-binding proteins and nuclear degradation: take the mRNA and run?. Mol. Cell 2010, 37:3-5.
23. Milligan L., Torchet C., Allmang C., Shipman T., Tollervey D. A nuclear surveillance pathway for mRNAs with defective polyadenylation. Mol. Cell. Biol. 2005, 25:9996-10004.
24. Minvielle-Sebastia L., Preker P.J., Wiederkehr T., Strahm Y., Keller W. The major yeast poly(A)-binding protein is associated with cleavage factor IA and functions in premessenger RNA 3'-end formation. Proc. Natl. Acad. Sci. USA 1997, 94:7897-7902.
25. Muhlemann O., Jensen T.H. mRNP quality control goes regulatory. Trends Genet. 2012, 28:70-77.
26. Neil H., Malabat C., d'Aubenton-Carafa Y., Xu Z., Steinmetz L.M., Jacquier A. Widespread bidirectional promoters are the major source of cryptic transcripts in yeast. Nature 2009, 457:1038-1042.
27. Qu X., Lykke-Andersen S., Nasser T., Saguez C., Bertrand E., Jensen T.H., Moore C. Assembly of an export-competent mRNP is needed for efficient release of the 3'-end processing complex after polyadenylation. Mol. Cell. Biol. 2009, 29:5327-5338.
28. Roth K.M., Wolf M.K., Rossi M., Butler J.S. The nuclear exosome contributes to autogenous control of NAB2 mRNA levels. Mol. Cell. Biol. 2005, 25:1577-1585.
29. Rougemaille M., Gudipati R.K., Olesen J.R., Thomsen R., Seraphin B., Libri D., Jensen T.H. Dissecting mechanisms of nuclear mRNA surveillance in THO/sub2 complex mutants. EMBO J. 2007, 26:2317-2326.
30. Sachs A.B., Davis R.W., Kornberg R.D. A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability. Mol. Cell Biol 1987, 7:3268-3276.
31. Saguez C., Schmid M., Olesen J.R., Ghazy M.A., Qu X., Poulsen M.B., Nasser T., Moore C., Jensen T.H. Nuclear mRNA surveillance in THO/sub2 mutants is triggered by inefficient polyadenylation. Mol. Cell 2008, 31:91-103.
32. St-Andre O., Lemieux C., Perreault A., Lackner D.H., Bahler J., Bachand F. Negative regulation of meiotic gene expression by the nuclear poly(a)-binding protein in fission yeast. J. Biol. Chem. 2010, 285:27859-27868.
33. Tutucci E., Stutz F. Keeping mRNPs in check during assembly and nuclear export. Nat. Rev. Mol. Cell Biol. 2011, 12:377-384.
34. Vanacova S., Wolf J., Martin G., Blank D., Dettwiler S., Friedlein A., Langen H., Keith G., Keller W. A new yeast poly(A) polymerase complex involved in RNA quality control. PLoS Biol. 2005, 3:e189. 10.1371/journal.pbio.0030189.
35. Viphakone N., Voisinet-Hakil F., Minvielle-Sebastia L. Molecular dissection of mRNA poly(A) tail length control in yeast. Nucleic Acids Res. 2008, 36:2418-2433.
36. Wyers F., Minet M., Dufour M.E., Vo L.T., Lacroute F. Deletion of the PAT1 gene affects translation initiation and suppresses a PAB1 gene deletion in yeast. Mol. Cell. Biol. 2000, 20:3538-3549.
37. Wyers F., Rougemaille M., Badis G., Rousselle J.C., Dufour M.E., Boulay J., Regnault B., Devaux F., Namane A., Seraphin B., et al. Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase. Cell 2005, 121:725-737.
38. Yamanaka S., Yamashita A., Harigaya Y., Iwata R., Yamamoto M. Importance of polyadenylation in the selective elimination of meiotic mRNAs in growing S. pombe cells. EMBO J. 2010, 29:2173-2181.