-
1
-
-
0030928619
-
Gene therapy — promises, problems and prospects
-
Verma, I.M. and Somia, N., Gene therapy — promises, problems and prospects, Nature, 389, 239-242, 1997.
-
(1997)
Nature
, vol.389
, pp. 239-242
-
-
Verma, I.M.1
Somia, N.2
-
2
-
-
0041806502
-
Looking into the safety of AAV vectors
-
Kay, M.A. and Nakai, H., Looking into the safety of AAV vectors, Nature, 424, 251, 2003.
-
(2003)
Nature
, vol.424
, pp. 251
-
-
Kay, M.A.1
Nakai, H.2
-
3
-
-
0037497338
-
Harmful potential of viral vectors fuels doubts over gene therapy
-
Check, E., Harmful potential of viral vectors fuels doubts over gene therapy, Nature, 423, 573-574, 2003.
-
(2003)
Nature
, vol.423
, pp. 573-574
-
-
Check, E.1
-
4
-
-
0035941087
-
Gene therapy: Safer and virus-free?
-
Ferber, D., Gene therapy: safer and virus-free?, Science, 294, 1638-1642, 2001.
-
(2001)
Science
, vol.294
, pp. 1638-1642
-
-
Ferber, D.1
-
5
-
-
0037057620
-
Regulators split on gene therapy as patient shows signs of cancer
-
Check, E., Regulators split on gene therapy as patient shows signs of cancer, Nature, 419, 545-546, 2002.
-
(2002)
Nature
, vol.419
, pp. 545-546
-
-
Check, E.1
-
6
-
-
0036190843
-
Utilization of synthetic peptides containing nuclear localization signals for nonviral gene transfer systems
-
Cartier, R. and Reszka, R., Utilization of synthetic peptides containing nuclear localization signals for nonviral gene transfer systems, Gene Ther., 9, 157-167, 2002.
-
(2002)
Gene Ther
, vol.9
, pp. 157-167
-
-
Cartier, R.1
Reszka, R.2
-
7
-
-
0036954247
-
Gene therapy progress and prospects: Nonviral vectors
-
Niidome, T. and Huang, L., Gene therapy progress and prospects: nonviral vectors, Gene Ther., 9, 1647-1652, 2002.
-
(2002)
Gene Ther
, vol.9
, pp. 1647-1652
-
-
Niidome, T.1
Huang, L.2
-
8
-
-
0037309716
-
Barriers to nonviral gene delivery
-
Christopher, M., Wiethoff, C., and Russell, M., Barriers to nonviral gene delivery, J. Pharm. Sci., 92, 203-217, 2003.
-
(2003)
J. Pharm. Sci
, vol.92
, pp. 203-217
-
-
Christopher, M.1
Wiethoff, C.2
Russell, M.3
-
9
-
-
0037294039
-
Non-viral and hybrid vectors in human gene therapy: An update
-
Schmidt-Wolf, G.D. and Schmidt-Wolf, I.G.H., Non-viral and hybrid vectors in human gene therapy: an update, Trends Mol. Med., 9, 67-72, 2003.
-
(2003)
Trends Mol. Med
, vol.9
, pp. 67-72
-
-
Schmidt-Wolf, G.D.1
Schmidt-Wolf, I.G.H.2
-
10
-
-
0037161316
-
Efficient intracellular drug and gene delivery using folate receptor-targeted pH-sensitive liposomes composed of cationic/anionic lipid combinations
-
Shi, G.F., Guo, W.J., Stephenson, S.M., and Lee, R.J., Efficient intracellular drug and gene delivery using folate receptor-targeted pH-sensitive liposomes composed of cationic/anionic lipid combinations, J. Controlled Release, 80, 309-319, 2002.
-
(2002)
J. Controlled Release
, vol.80
, pp. 309-319
-
-
Shi, G.F.1
Guo, W.J.2
Stephenson, S.M.3
Lee, R.J.4
-
11
-
-
0037452668
-
Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome-DNA complexes
-
Torchilin, V.P., Levchenko, T.S., Rammohan, R., Volodina, N., Sternberg, B.P., and D’Souza, G.G.M., Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome-DNA complexes, Proc. Natl. Acad. Sci., 100, 1972-1977, 2003.
-
(2003)
Proc. Natl. Acad. Sci
, vol.100
, pp. 1972-1977
-
-
Torchilin, V.P.1
Levchenko, T.S.2
Rammohan, R.3
Volodina, N.4
Sternberg, B.P.5
D’Souza, G.G.M.6
-
12
-
-
0036363610
-
Jet nebulization of PEI/DNA polyplexes: Physical stability and in vitro gene delivery efficiency
-
Rudolph, C., Müller, R.H., and Rosenecker, J., Jet nebulization of PEI/DNA polyplexes: physical stability and in vitro gene delivery efficiency, J. Gene. Med., 4, 66-74, 2002.
-
(2002)
J. Gene. Med
, vol.4
, pp. 66-74
-
-
Rudolph, C.1
Müller, R.H.2
Rosenecker, J.3
-
13
-
-
0033137012
-
Efficient gene transfer by histidylated polylysine/pDNA complexes
-
Midoux, P. and Monsigny, M., Efficient gene transfer by histidylated polylysine/pDNA complexes, Bioconjug. Chem., 10, 406-411, 1999.
-
(1999)
Bioconjug. Chem
, vol.10
, pp. 406-411
-
-
Midoux, P.1
Monsigny, M.2
-
14
-
-
0041867570
-
Dextran-spermine conjugate: An efficient vector for gene delivery
-
Azzam, T., Eliyahu, H., Makovitzki, A., and Domb, A.J., Dextran-spermine conjugate: an efficient vector for gene delivery, Macromol. Symp., 195, 247-262, 2003.
-
(2003)
Macromol. Symp
, vol.195
, pp. 247-262
-
-
Azzam, T.1
Eliyahu, H.2
Makovitzki, A.3
Domb, A.J.4
-
15
-
-
0345352683
-
Amphiphilic dendrimers: Novel self-assembling vectors for efficient gene delivery
-
Joester, D., Losson, M., Pugin, R., Heinzelmann, H., Walter, E., Merkle, H.P., and Diederich, F., Amphiphilic dendrimers: novel self-assembling vectors for efficient gene delivery, Ang. Chem. Int. Ed., 42, 1486-1490, 2003.
-
(2003)
Ang. Chem. Int. Ed
, vol.42
, pp. 1486-1490
-
-
Joester, D.1
Losson, M.2
Pugin, R.3
Heinzelmann, H.4
Walter, E.5
Merkle, H.P.6
Diederich, F.7
-
16
-
-
0042311016
-
Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery
-
Anderson, D.G., Lynn, D.M., and Langer, R., Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery, Ang. Chem. Int. Ed., 42, 3153-3158, 2003.
-
(2003)
Ang. Chem. Int. Ed
, vol.42
, pp. 3153-3158
-
-
Anderson, D.G.1
Lynn, D.M.2
Langer, R.3
-
17
-
-
0037194089
-
A potential gene delivery vector: N-isopropy-lacrylamide-ethyleneimine block copolymers
-
Dinger, S., Tuncel, A., and Piskin, E., A potential gene delivery vector: N-isopropy-lacrylamide-ethyleneimine block copolymers, Macromol. Chem. Phys., 203, 1460-1465, 2002.
-
(2002)
Macromol. Chem. Phys
, vol.203
, pp. 1460-1465
-
-
Dinger, S.1
Tuncel, A.2
Piskin, E.3
-
18
-
-
0032580495
-
DNA-polycation nanospheres as non-viral gene delivery vehicles
-
Leong, K.W., Mao, H.Q., Truong-Le, V.L., Roy, K., Walsh, S.M., and August, J.T., DNA-polycation nanospheres as non-viral gene delivery vehicles, J. Controlled Release, 53, 183-193, 1998.
-
(1998)
J. Controlled Release
, vol.53
, pp. 183-193
-
-
Leong, K.W.1
Mao, H.Q.2
Truong-Le, V.L.3
Roy, K.4
Walsh, S.M.5
August, J.T.6
-
19
-
-
0034129986
-
Gene transfer into hepatoma cells mediated by galactose-modified -helical peptides
-
Niidome, T., Urakawa, M., Sato, H., Takahara, Y., Anai, T., Hatakayama, T., Wada, A., Hirayama, T., and Aoyagi, H., Gene transfer into hepatoma cells mediated by galactose-modified -helical peptides, Biomaterials, 21, 1811-1819, 2000.
-
(2000)
Biomaterials
, vol.21
, pp. 1811-1819
-
-
Niidome, T.1
Urakawa, M.2
Sato, H.3
Takahara, Y.4
Anai, T.5
Hatakayama, T.6
Wada, A.7
Hirayama, T.8
Aoyagi, H.9
-
20
-
-
0035965501
-
Gene delivery with synthetic (Non viral) carriers
-
Brown, M.D., Schätzlein, A.G., and Uchegbu, I.F., Gene delivery with synthetic (non viral) carriers, Int. J. Pharm., 229, 1-21, 2001.
-
(2001)
Int. J. Pharm
, vol.229
, pp. 1-21
-
-
Brown, M.D.1
Schätzlein, A.G.2
Uchegbu, I.F.3
-
21
-
-
0032917517
-
Effect of chitosan on epithelial permeability and structure
-
Dodane, V., Khan, M.A., and Merwin, J.R., Effect of chitosan on epithelial permeability and structure, Int. J. Pharm., 182, 21-32, 1999.
-
(1999)
Int. J. Pharm
, vol.182
, pp. 21-32
-
-
Dodane, V.1
Khan, M.A.2
Merwin, J.R.3
-
22
-
-
0034823205
-
Chitosan and its derivatives in mucosal drug and vaccine delivery
-
van der Lubben, I.M., Verhoef, J.C., Borchard, G., and Junginger, H.E., Chitosan and its derivatives in mucosal drug and vaccine delivery, Eur. J. Pharm. Sci., 14, 201-207, 2001.
-
(2001)
Eur. J. Pharm. Sci
, vol.14
, pp. 201-207
-
-
Van Der Lubben, I.M.1
Verhoef, J.C.2
Borchard, G.3
Junginger, H.E.4
-
23
-
-
0035875980
-
Vitro degradation of chitosan by a commercial enzyme preparation: Effect of molecular weight and degree of deacetylation
-
Zhang, H. and Neau, S.H., In vitro degradation of chitosan by a commercial enzyme preparation: effect of molecular weight and degree of deacetylation, Biomaterials, 22, 1653-1658, 2001.
-
(2001)
Biomaterials
, vol.22
, pp. 1653-1658
-
-
Zhang, H.1
Neau, S.H.2
-
24
-
-
0035801903
-
Mechanism of cell transfection with plasmid/chi-tosan complexes
-
Ishii, T., Okahata, Y., and Sato, T., Mechanism of cell transfection with plasmid/chi-tosan complexes, Biomembranes, 1514, 51-64, 2001.
-
(2001)
Biomembranes
, vol.1514
, pp. 51-64
-
-
Ishii, T.1
Okahata, Y.2
Sato, T.3
-
25
-
-
0035839201
-
Chitosan-based nanoparticles for topical genetic immunization
-
Cui, Z. and Mumper, R.J., Chitosan-based nanoparticles for topical genetic immunization, J. Controlled Release, 75, 409-419, 2001.
-
(2001)
J. Controlled Release
, vol.75
, pp. 409-419
-
-
Cui, Z.1
Mumper, R.J.2
-
26
-
-
0032580495
-
DNA-polycation nanospheres as non-viral gene delivery vehicles
-
Leong, K.W., Mao, H.Q., Truong-Le, V.L., Roy, K., Walsh, S.M., and August, J.T., DNA-polycation nanospheres as non-viral gene delivery vehicles, J. Controlled Release, 53, 183-193, 1998.
-
(1998)
J. Controlled Release
, vol.53
, pp. 183-193
-
-
Leong, K.W.1
Mao, H.Q.2
Truong-Le, V.L.3
Roy, K.4
Walsh, S.M.5
August, J.T.6
-
27
-
-
0035937593
-
Polysaccharide colloidal particles as delivery systems for macromolecules
-
Janes, K.A., Calvo, P., and Alonso, M.J., Polysaccharide colloidal particles as delivery systems for macromolecules, Adv. Drug Deliv. Rev., 47, 83-97, 2001.
-
(2001)
Adv. Drug Deliv. Rev
, vol.47
, pp. 83-97
-
-
Janes, K.A.1
Calvo, P.2
Alonso, M.J.3
-
28
-
-
0036059090
-
Polyethyleneimine/chitosan hexamer-mediated gene transfection into intestinal epithelial cell cultured in serum-containing medium
-
Ouji, Y., Terakura, A.Y., Hayashi, Y., Maeda, I., Kawase, M., Yamato, E., Miyazaki, J., and Yagi, K., Polyethyleneimine/chitosan hexamer-mediated gene transfection into intestinal epithelial cell cultured in serum-containing medium, J. Biosci. Bioeng. 94, 81-83, 2002.
-
(2002)
J. Biosci. Bioeng
, vol.94
, pp. 81-83
-
-
Ouji, Y.1
Terakura, A.Y.2
Hayashi, Y.3
Maeda, I.4
Kawase, M.5
Yamato, E.6
Miyazaki, J.7
Yagi, K.8
-
29
-
-
0037472115
-
Chitosan-based gastrointestinal delivery systems
-
Hejazi, R. and Amiji, M., Chitosan-based gastrointestinal delivery systems, J. Controlled Release, 89, 151-165, 2003.
-
(2003)
J. Controlled Release
, vol.89
, pp. 151-165
-
-
Hejazi, R.1
Amiji, M.2
-
30
-
-
0002739717
-
Influence of chitosans with various molecular weights and degrees of deacetylation on the permeability of human intestinal epithelial cells (Caco-2)
-
R.A.A., Muzzarelli, Ed., Atec, Grottammare, Italy
-
Holme, H.K., Hagen, A., and Dornish, M., Influence of chitosans with various molecular weights and degrees of deacetylation on the permeability of human intestinal epithelial cells (Caco-2), in Chitosan Per Os From Dietary Supplement To Drug Carrier, R.A.A., Muzzarelli, Ed., Atec, Grottammare, Italy, 2000, pp. 127-136.
-
(2000)
Chitosan per Os from Dietary Supplement to Drug Carrier
, pp. 127-136
-
-
Holme, H.K.1
Hagen, A.2
Dornish, M.3
-
31
-
-
0004472732
-
Evaluation of the biological properties of soluble chitosan and chitosan microspheres
-
Carreno-Gomez, B. and Duncan, R., Evaluation of the biological properties of soluble chitosan and chitosan microspheres, Int. J. Pharm., 148, 231-240, 1997.
-
(1997)
Int. J. Pharm
, vol.148
, pp. 231-240
-
-
Carreno-Gomez, B.1
Duncan, R.2
-
32
-
-
0035478758
-
Chitosan and its derivatives as intestinal absorption enhancers
-
Verhoef, J.C., Junginger, H.E., and Thanou, M., Chitosan and its derivatives as intestinal absorption enhancers, Adv. Drug. Deliv. Rev., 50, S91-S101, 2001.
-
(2001)
Adv. Drug. Deliv. Rev
, vol.50
, pp. SS91-S101
-
-
Verhoef, J.C.1
Junginger, H.E.2
Thanou, M.3
-
33
-
-
0037015322
-
Interaction of low-molecular-weight chitosan with mimic membrane studied by electrochemical methods and surface plasmon resonance
-
Yang, F., Cui, X.Q., and Yang, X.R., Interaction of low-molecular-weight chitosan with mimic membrane studied by electrochemical methods and surface plasmon resonance, Biophys. Chem., 99, 99-106, 2002.
-
(2002)
Biophys. Chem
, vol.99
, pp. 99-106
-
-
Yang, F.1
Cui, X.Q.2
Yang, X.R.3
-
34
-
-
0037067303
-
Chitosan-induced perturbation of dipalmitoyl-sn-glycero-3-phosphocholine membrane bilayer
-
Chan, V., Mao, H.Q., and Leong, K.W., Chitosan-induced perturbation of dipalmitoyl-sn-glycero-3-phosphocholine membrane bilayer, Langmuir, 17, 3749-3756, 2001.
-
(2001)
Langmuir
, vol.17
, pp. 3749-3756
-
-
Chan, V.1
Mao, H.Q.2
Leong, K.W.3
-
35
-
-
0032114834
-
Physico-chemical characterization of chitosans varying in degree of acetylation
-
Berth, G., Dautzwnberg, H., and Peter, M.G., Physico-chemical characterization of chitosans varying in degree of acetylation, Carbohydr. Polym., 36, 205-216, 1998.
-
(1998)
Carbohydr. Polym
, vol.36
, pp. 205-216
-
-
Berth, G.1
Dautzwnberg, H.2
Peter, M.G.3
-
36
-
-
0035668731
-
Interactions of phospholipid bilayer with chitosan: Effect of molecular weight and pH
-
Fang, N., Chan, V., Mao, H.Q., and Leong, K.W., Interactions of phospholipid bilayer with chitosan: effect of molecular weight and pH, Biomacromol., 2, 1161-1168, 2001.
-
(2001)
Biomacromol
, vol.2
, pp. 1161-1168
-
-
Fang, N.1
Chan, V.2
Mao, H.Q.3
Leong, K.W.4
-
37
-
-
0034894217
-
Two types of hydrophobic aggregates in aqueous solutions of chitosan and its hydrophobic derivative
-
Philippova, O.E., Volkov, E.V., Sitnikova, N.L., and Khokhlov, A.R., Two types of hydrophobic aggregates in aqueous solutions of chitosan and its hydrophobic derivative, Biomacromolecules, 2, 483-490, 2001.
-
(2001)
Biomacromolecules
, vol.2
, pp. 483-490
-
-
Philippova, O.E.1
Volkov, E.V.2
Sitnikova, N.L.3
Khokhlov, A.R.4
-
38
-
-
0141592643
-
Self-aggregation behavior of alkylated chitosan and its effect on the release of a hydrophobic drug
-
Liu, W.G., Sun, S.J., Zhang, X., and Yao, K.D., Self-aggregation behavior of alkylated chitosan and its effect on the release of a hydrophobic drug, J. Biomater. Sci. Polym. Ed., 14, 851-859, 2003.
-
(2003)
J. Biomater. Sci. Polym. Ed
, vol.14
, pp. 851-859
-
-
Liu, W.G.1
Sun, S.J.2
Zhang, X.3
Yao, K.D.4
-
39
-
-
0038793492
-
A-Alkylated chitosan as a potential nonviral vector for gene transfection
-
Liu, W.G., Zhang, X., Sun, S.J., Sun, G.J., and Yao, K.D., A-Alkylated chitosan as a potential nonviral vector for gene transfection, Bioconjug. Chem., 14, 782-789, 2003.
-
(2003)
Bioconjug. Chem
, vol.14
, pp. 782-789
-
-
Liu, W.G.1
Zhang, X.2
Sun, S.J.3
Sun, G.J.4
Yao, K.D.5
-
40
-
-
0031801218
-
Chitosan-membrane interactions and their probable role in chitosan-mediated transfection
-
Venkatesh, S. and Smith, T.J., Chitosan-membrane interactions and their probable role in chitosan-mediated transfection, Biotechnol. Appl. Biochem., 27, 265-267, 1998.
-
(1998)
Biotechnol. Appl. Biochem
, vol.27
, pp. 265-267
-
-
Venkatesh, S.1
Smith, T.J.2
-
41
-
-
0029083378
-
Novel polymeric condensing carriers for gene delivery
-
Mumper, R.J., Wang, J., Claspell, J.M., and Rolland, A.P., Novel polymeric condensing carriers for gene delivery, Proceedings of the International Symposium of Controlled Release of Bioactive Materials, 22, 1995, pp. 178-179.
-
(1995)
Proceedings of the International Symposium of Controlled Release of Bioactive Materials
, vol.22
, pp. 178-179
-
-
Mumper, R.J.1
Wang, J.2
Claspell, J.M.3
Rolland, A.P.4
-
42
-
-
0035424424
-
Vitro gene delivery mediated by chitosan. Effect of pH, serum, and molecular mass of chitosan on the transfection efficiency
-
Sato, T., Ishii, T., and Okahata, Y., In vitro gene delivery mediated by chitosan. Effect of pH, serum, and molecular mass of chitosan on the transfection efficiency, Biomaterials, 22, 2075-2080, 2001.
-
(2001)
Biomaterials
, vol.22
, pp. 2075-2080
-
-
Sato, T.1
Ishii, T.2
Okahata, Y.3
-
43
-
-
0032990267
-
Potential of low molecular mass chitosan as a DNA delivery system: Biocompatibility, body distribution and ability to complex and protect DNA
-
Richardson, S.C.W., Kolbe, H.V.J., and Duncan, R., Potential of low molecular mass chitosan as a DNA delivery system: biocompatibility, body distribution and ability to complex and protect DNA, Int. J. Pharm., 178, 231-243, 1999.
-
(1999)
Int. J. Pharm
, vol.178
, pp. 231-243
-
-
Richardson, S.C.W.1
Kolbe, H.V.J.2
Duncan, R.3
-
44
-
-
0032484162
-
Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery
-
MacLaughlin, F.C., Mumper, R.J., Wang, J.J., Tagliaferri, J.M., Gill, I., Hinchcliffe, M., and Rolland, A.P., Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery, J. Controlled Release, 56, 259-272, 1998.
-
(1998)
J. Controlled Release
, vol.56
, pp. 259-272
-
-
Maclaughlin, F.C.1
Mumper, R.J.2
Wang, J.J.3
Tagliaferri, J.M.4
Gill, I.5
Hinchcliffe, M.6
Rolland, A.P.7
-
45
-
-
85057261798
-
Chitosan Related Compositions and Methods for Delivery of Nucleic Acids and Oligonucleotides into a Cell
-
Rolland, A. and Mumper, R.J., Chitosan Related Compositions and Methods for Delivery of Nucleic Acids and Oligonucleotides into a Cell, US Patent, 6,184,037, 2001.
-
(2001)
US Patent, 6,184,037
-
-
Rolland, A.1
Mumper, R.J.2
-
46
-
-
0034786764
-
Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethyleneimine in vitro and after lung administration in vivo
-
Koping-Hoggard, M., Tubulekas, I., Guan, H., et al., Chitosan as a nonviral gene delivery system. structure-property relationships and characteristics compared with polyethyleneimine in vitro and after lung administration in vivo, Gene Ther., 8, 1108-1121, 2001.
-
(2001)
Gene Ther
, vol.8
, pp. 1108-1121
-
-
Koping-Hoggard, M.1
Tubulekas, I.2
Guan, H.3
-
47
-
-
0038004448
-
A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethyleneimine: Effect of molecular weight on transfection efficiency and cytotoxicity
-
Fischer, D., Bieber, T., Li, Y., et al., A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethyleneimine: effect of molecular weight on transfection efficiency and cytotoxicity, Pharm. Res., 16, 1273-1279, 1999.
-
(1999)
Pharm. Res
, vol.16
, pp. 1273-1279
-
-
Fischer, D.1
Bieber, T.2
Li, Y.3
-
48
-
-
0242322948
-
Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo
-
Koping-Hoggard, M., Mel’nikova, Y.S., Varum, K.M., Lindman, B., and Artursson, P., Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo, J. Gene. Med., 5, 130-141, 2003.
-
(2003)
J. Gene. Med
, vol.5
, pp. 130-141
-
-
Koping-Hoggard, M.1
Mel’Nikova, Y.S.2
Varum, K.M.3
Lindman, B.4
Artursson, P.5
-
49
-
-
0035936972
-
Chitosan-DNA nanoparticles as gene carriers: Synthesis, characterization and transfection efficiency
-
Mao, H.Q., Roy, K., Troung-Le, V.L., Janes, K.A., Lin, K.Y., Wang, Y., August, J.T., and Leong, K.W., Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency, J. Controlled Release, 70, 399-421, 2001.
-
(2001)
J. Controlled Release
, vol.70
, pp. 399-421
-
-
Mao, H.Q.1
Roy, K.2
Troung-Le, V.L.3
Janes, K.A.4
Lin, K.Y.5
Wang, Y.6
August, J.T.7
Leong, K.W.8
-
50
-
-
0034975453
-
Mesenchymal stem cells: Building blocks for molecular medicine in the 21st century
-
Caplan, A.I. and Bruder, S.P., Mesenchymal stem cells: building blocks for molecular medicine in the 21st century, Trends Mol. Med., 7, 259-264, 2001.
-
(2001)
Trends Mol. Med
, vol.7
, pp. 259-264
-
-
Caplan, A.I.1
Bruder, S.P.2
-
51
-
-
0037340617
-
Mesenchymal stem cells, MG63 and HEK293 transfection using chitosan-DNA nanoparticles
-
Corsi, K., Chellat, F., Yahia, L., and Fernandes, J.C., Mesenchymal stem cells, MG63 and HEK293 transfection using chitosan-DNA nanoparticles, Biomaterials, 24, 1255-1264, 2003.
-
(2003)
Biomaterials
, vol.24
, pp. 1255-1264
-
-
Corsi, K.1
Chellat, F.2
Yahia, L.3
Fernandes, J.C.4
-
52
-
-
0032866489
-
The effect of regional gene therapy with bone morphogenetic protein-2-producing bone-marrow cells on the repair of segmental femoral defects in rats
-
Lieberman, J.R., Daluiski, A., Stevenson, S., Wu, L., McAllister, P., Lee, Y.P., Kabo, J.M., Finerman, G.A., Berk, A.J., and Witte, O.N., The effect of regional gene therapy with bone morphogenetic protein-2-producing bone-marrow cells on the repair of segmental femoral defects in rats, J. Bone. J. Surg. Am., 81, 905-917, 1999.
-
(1999)
J. Bone. J. Surg. Am
, vol.81
, pp. 905-917
-
-
Lieberman, J.R.1
Daluiski, A.2
Stevenson, S.3
Wu, L.4
McAllister, P.5
Lee, Y.P.6
Kabo, J.M.7
Finerman, G.A.8
Berk, A.J.9
Witte, O.N.10
-
53
-
-
0030837792
-
Class I-restricted CTL induction by mucosal immunization with naked DNA encoding measles virus haemagglutinin
-
Etchart, N., Buckland, R., Liu, M.A., Wild, T.F., and Kaiserlian, D., Class I-restricted CTL induction by mucosal immunization with naked DNA encoding measles virus haemagglutinin, J. Gen. Virol., 78, 1577-1580, 1997.
-
(1997)
J. Gen. Virol
, vol.78
, pp. 1577-1580
-
-
Etchart, N.1
Buckland, R.2
Liu, M.A.3
Wild, T.F.4
Kaiserlian, D.5
-
54
-
-
0032958073
-
Oral gene delivery with chi-tosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy
-
Roy, K., Mao, H.Q., Huang, S.K., and Leong, K.W., Oral gene delivery with chi-tosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy, Nat. Med., 5, 387-391, 1999.
-
(1999)
Nat. Med
, vol.5
, pp. 387-391
-
-
Roy, K.1
Mao, H.Q.2
Huang, S.K.3
Leong, K.W.4
-
55
-
-
0038513487
-
Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice
-
Chew, J.L., Wolfowicz, C.B., Mao, H.Q., Leong, K.W., and Chua, K.Y., Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice, Vaccine, 21, 2720-2729, 2003.
-
(2003)
Vaccine
, vol.21
, pp. 2720-2729
-
-
Chew, J.L.1
Wolfowicz, C.B.2
Mao, H.Q.3
Leong, K.W.4
Chua, K.Y.5
-
56
-
-
0035839201
-
Chitosan-based nanoparticles for topical genetic immunization
-
Cui, Z. and Mumper, R.J., Chitosan-based nanoparticles for topical genetic immunization, J. Controlled Release, 75, 409-419, 2001.
-
(2001)
J. Controlled Release
, vol.75
, pp. 409-419
-
-
Cui, Z.1
Mumper, R.J.2
-
57
-
-
0030754344
-
Optimization of formulations and conditions for the aerosol delivery of functional cationic lipid:DNA complexes
-
Eastman, S.J., Tousignant, J.D., Lukason, M.J., Murray, H., Siegel, C.S., Constantino, P., Harris, D.J., Cheng, S.H., and Scheule, R.K., Optimization of formulations and conditions for the aerosol delivery of functional cationic lipid:DNA complexes, Hum. Gene Ther., 8, 313-322, 1997.
-
(1997)
Hum. Gene Ther
, vol.8
, pp. 313-322
-
-
Eastman, S.J.1
Tousignant, J.D.2
Lukason, M.J.3
Murray, H.4
Siegel, C.S.5
Constantino, P.6
Harris, D.J.7
Cheng, S.H.8
Scheule, R.K.9
-
58
-
-
0037309687
-
Pulmonary gene delivery by chitosan-pDNA complex powder prepared by a supercritical carbon dioxide process
-
Okamoto, H., Nishida, S., Todo, H., Sakakura, Y., Iida, K., and Danjo, K., Pulmonary gene delivery by chitosan-pDNA complex powder prepared by a supercritical carbon dioxide process, J. Pharm. Sci. 92, 371-380, 2003.
-
(2003)
J. Pharm. Sci
, vol.92
, pp. 371-380
-
-
Okamoto, H.1
Nishida, S.2
Todo, H.3
Sakakura, Y.4
Iida, K.5
Danjo, K.6
-
59
-
-
0036027454
-
Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines
-
Thanou, M., Florea, B.I., Geldof, M., Junginger, H.E., and Borchard, G., Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines, Biomaterials, 23, 153-159, 2002.
-
(2002)
Biomaterials
, vol.23
, pp. 153-159
-
-
Thanou, M.1
Florea, B.I.2
Geldof, M.3
Junginger, H.E.4
Borchard, G.5
-
60
-
-
0032509928
-
Preparation of chitosan self-aggregates as a gene delivery system
-
Lee, K.Y., Kwon, I.C., Kim, Y.H., Jo, W.H., and Jeong, S.Y., Preparation of chitosan self-aggregates as a gene delivery system, J. Controlled Release, 51, 213-220, 1998.
-
(1998)
J. Controlled Release
, vol.51
, pp. 213-220
-
-
Lee, K.Y.1
Kwon, I.C.2
Kim, Y.H.3
Jo, W.H.4
Jeong, S.Y.5
-
61
-
-
0035213983
-
Structural characteristics of size-controlled self-aggregates of deoxy-cholic acid-modified chitosan and their application as a DNA delivery carrier
-
Kim, Y.H., Gihm, S.H., Park, C.R., Lee, K.Y., Kim, T.W., Kwon, I.C., Chung, H., and Jeong, S.Y., Structural characteristics of size-controlled self-aggregates of deoxy-cholic acid-modified chitosan and their application as a DNA delivery carrier, Bioconjugate Chem., 12, 932-938, 2001.
-
(2001)
Bioconjugate Chem
, vol.12
, pp. 932-938
-
-
Kim, Y.H.1
Gihm, S.H.2
Park, C.R.3
Lee, K.Y.4
Kim, T.W.5
Kwon, I.C.6
Chung, H.7
Jeong, S.Y.8
-
62
-
-
0031722107
-
Chitosan-based vector/DNA complexes for gene delivery: Biophysical characteristics and transfection ability
-
Erbacher, P., Zou, S.M., Bettinger, T., Steffan, A.M., and Remy, J.S., Chitosan-based vector/DNA complexes for gene delivery: biophysical characteristics and transfection ability, Pharm. Res., 15, 1332-1339, 1998.
-
(1998)
Pharm. Res
, vol.15
, pp. 1332-1339
-
-
Erbacher, P.1
Zou, S.M.2
Bettinger, T.3
Steffan, A.M.4
Remy, J.S.5
-
63
-
-
0037130565
-
Chitosan and its derivatives — a promising non-viral vector for gene transfection
-
Liu, W.G. and Yao, K.D., Chitosan and its derivatives — a promising non-viral vector for gene transfection, J. Controlled Release, 83, 1-11, 2002.
-
(2002)
J. Controlled Release
, vol.83
, pp. 1-11
-
-
Liu, W.G.1
Yao, K.D.2
-
64
-
-
0035813684
-
Chitosans for gene delivery
-
Borchard, G., Chitosans for gene delivery, Adv. Drug Deliv. Rev., 52, 145-150, 2001.
-
(2001)
Adv. Drug Deliv. Rev
, vol.52
, pp. 145-150
-
-
Borchard, G.1
-
65
-
-
0022517619
-
Receptor-mediated endocytosis: The intracellular journey of transferrin and its receptor
-
Dautry-Varsat, A., Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor, Biochimie, 68, 375-381, 1986.
-
(1986)
Biochimie
, vol.68
, pp. 375-381
-
-
Dautry-Varsat, A.1
-
66
-
-
0027984829
-
Receptor-mediated peptide delivery in pulmonary epithelial monolayers
-
Deshpande, D., Velasquez, D.T., Wang, L.Y., et al., Receptor-mediated peptide delivery in pulmonary epithelial monolayers, Pharm. Res., 11, 1121-1126, 1994.
-
(1994)
Pharm. Res
, vol.11
, pp. 1121-1126
-
-
Deshpande, D.1
Velasquez, D.T.2
Wang, L.Y.3
-
67
-
-
17344362958
-
Controlled gene delivery by DNA-gelatin nanospheres
-
Truong-Le, V.L., August, J.T., and Leong, K.W., Controlled gene delivery by DNA-gelatin nanospheres, Hum. Gene Ther., 9, 1709-1717, 1998.
-
(1998)
Hum. Gene Ther
, vol.9
, pp. 1709-1717
-
-
Truong-Le, V.L.1
August, J.T.2
Leong, K.W.3
-
68
-
-
0032837918
-
Gene transfer by DNA-gelatin nanospheres
-
Truong-Le, V.L., Walsh, S.M., Schweibert, E., et al., Gene transfer by DNA-gelatin nanospheres, Arch. Biochem. Biophys., 361, 47-56, 1999.
-
(1999)
Arch. Biochem. Biophys
, vol.361
, pp. 47-56
-
-
Truong-Le, V.L.1
Walsh, S.M.2
Schweibert, E.3
-
69
-
-
0345059269
-
Gene delivery mediated by cationic liposomes: From biophysical aspects to enhancement of transfection
-
de Lima, M.C., Simoes, S., Pires, P., et al., Gene delivery mediated by cationic liposomes: from biophysical aspects to enhancement of transfection, Mol. Membr. Biol., 6, 103-109, 1999.
-
(1999)
Mol. Membr. Biol
, vol.6
, pp. 103-109
-
-
De Lima, M.C.1
Simoes, S.2
Pires, P.3
-
70
-
-
0035936972
-
Chitosan-DNA nanoparticles as gene carriers: Synthesis, characterization and transfection efficiency
-
Mao, H.Q., Roy, K., Troung-Le, V.L., Janes, K.A., Lin, K.Y., Wang, Y., August, J.T., and Leong, K.W., Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency, J. Controlled Release, 70, 399-421, 2001.
-
(2001)
J. Controlled Release
, vol.70
, pp. 399-421
-
-
Mao, H.Q.1
Roy, K.2
Troung-Le, V.L.3
Janes, K.A.4
Lin, K.Y.5
Wang, Y.6
August, J.T.7
Leong, K.W.8
-
71
-
-
0034738843
-
Transfection efficiency increases by incorporating hydrophobic monomer units into polymeric gene carriers
-
Kurisawa, M., Yokoyama, M., and Okano, T., Transfection efficiency increases by incorporating hydrophobic monomer units into polymeric gene carriers, J. Controlled Release, 68, 1-8, 2000.
-
(2000)
J. Controlled Release
, vol.68
, pp. 1-8
-
-
Kurisawa, M.1
Yokoyama, M.2
Okano, T.3
-
72
-
-
0028853753
-
Preparation and characterization of DNA-lipoglutamate complexes
-
Sato, T., Kawakami, T., Shirakawa, N., and Okahata, Y., Preparation and characterization of DNA-lipoglutamate complexes, Bull. Chem. Soc. Jpn., 68, 2709-2715, 1995.
-
(1995)
Bull. Chem. Soc. Jpn
, vol.68
, pp. 2709-2715
-
-
Sato, T.1
Kawakami, T.2
Shirakawa, N.3
Okahata, Y.4
-
73
-
-
0029136052
-
DNA complexes with polycations for the delivery of genetic materials into cells
-
Kabanov, A.V. and Kabanov, V.A., DNA complexes with polycations for the delivery of genetic materials into cells, Bioconjug. Chem., 6, 7-20, 1995.
-
(1995)
Bioconjug. Chem
, vol.6
, pp. 7-20
-
-
Kabanov, A.V.1
Kabanov, V.A.2
-
74
-
-
0033357206
-
Charge inversion in DNA-amphiphile complexes: Possible application to gene therapy
-
Kuhn, P.S., Levin, Y., and Barbosa, M.C., Charge inversion in DNA-amphiphile complexes: possible application to gene therapy, Physica A, 274, 8-18, 1999.
-
(1999)
Physica A
, vol.274
, pp. 8-18
-
-
Kuhn, P.S.1
Levin, Y.2
Barbosa, M.C.3
-
75
-
-
0025043480
-
The asialoglycoprotein receptor: A model for endocytic transport receptors
-
Spiess, M., The asialoglycoprotein receptor: a model for endocytic transport receptors, Biochemistry, 29, 10009-10018, 1990.
-
(1990)
Biochemistry
, vol.29
, pp. 10009-10018
-
-
Spiess, M.1
-
76
-
-
0034601856
-
Galactosylated chitosan-graft-dextran as hepatocyte-targeting DNA carrier
-
Park, Y.K., Park, Y.H., Shin, B.A., Choi, E.S., Park, Y.R., Akaike, T., and Cho, C.S., Galactosylated chitosan-graft-dextran as hepatocyte-targeting DNA carrier, J. Controlled Release, 69, 97-108, 2000.
-
(2000)
J. Controlled Release
, vol.69
, pp. 97-108
-
-
Park, Y.K.1
Park, Y.H.2
Shin, B.A.3
Choi, E.S.4
Park, Y.R.5
Akaike, T.6
Cho, C.S.7
-
77
-
-
0035914230
-
Galactosylated chitosan-graft-poly(Ethylene glycol) as hepatocyte-tar-geting DNA carrier
-
Park, I.K., Kim, T.H., Park, Y.H., Shin, B.A., Choi, E.S., Chowdhury, E.H., Akaike, T., and Cho, C.S., Galactosylated chitosan-graft-poly(ethylene glycol) as hepatocyte-tar-geting DNA carrier, J. Controlled Release, 76, 349-362, 2001.
-
(2001)
J. Controlled Release
, vol.76
, pp. 349-362
-
-
Park, I.K.1
Kim, T.H.2
Park, Y.H.3
Shin, B.A.4
Choi, E.S.5
Chowdhury, E.H.6
Akaike, T.7
Cho, C.S.8
-
78
-
-
0037433814
-
Visualization of transfection of hepatocytes by galactosylated chitosan-graft-poly(Ethylene glycol)/DNA complexes by confocal laser scanning microscopy
-
Park, I.K., Kim, T.H., Kim, S.I., Park, Y.H., Kim, W.J., Akaike, T., and Cho, C.S., Visualization of transfection of hepatocytes by galactosylated chitosan-graft-poly(ethylene glycol)/DNA complexes by confocal laser scanning microscopy, Int. J. Pharm., 257, 103-110, 2003.
-
(2003)
Int. J. Pharm
, vol.257
, pp. 103-110
-
-
Park, I.K.1
Kim, T.H.2
Kim, S.I.3
Park, Y.H.4
Kim, W.J.5
Akaike, T.6
Cho, C.S.7
-
79
-
-
85057288548
-
Tracking the intracellular path of poly(Ethylenimine)/DNA complexes for gene delivery
-
Godbey, W.T., Wu, K.K., and Mikos, A.G., Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery, Proc. Natl. Acad. Sci. USA., 99, 7467-7471, 2002.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7467-7471
-
-
Godbey, W.T.1
Wu, K.K.2
Mikos, A.G.3
-
80
-
-
0037386523
-
Efficient active transport of gene nanocarriers to the cell nucleus
-
Suh, J., Wirtz, D., and Hanes, J., Efficient active transport of gene nanocarriers to the cell nucleus, Proc. Natl. Acad. Sci. USA, 100, 3878-3882, 2003.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3878-3882
-
-
Suh, J.1
Wirtz, D.2
Hanes, J.3
-
81
-
-
0037449515
-
Galactosylated chitosan (GC)-graft-poly(vinyl pyrrolidone) (PVP) as hepato-cyte-targeting DNA carrier preparation and physicochemical characterization of GC-graft-PVP/DNA complex
-
Park, I.K., Ihm, J.E., Park, Y.H., Choi, Y.J., Kim, S.I., Kim, W.J., Akaike, T., and Cho, C.S., Galactosylated chitosan (GC)-graft-poly(vinyl pyrrolidone) (PVP) as hepato-cyte-targeting DNA carrier preparation and physicochemical characterization of GC-graft-PVP/DNA complex, J. Controlled Release, 86, 349-359, 2003.
-
(2003)
J. Controlled Release
, vol.86
, pp. 349-359
-
-
Park, I.K.1
Ihm, J.E.2
Park, Y.H.3
Choi, Y.J.4
Kim, S.I.5
Kim, W.J.6
Akaike, T.7
Cho, C.S.8
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